Mercury inhibits the L170C mutant of aquaporin Z by making waters clog the water channel

Biophysical Chemistry

Volumn 160, Issue 1, 2012, Pages 69-74

  Zhang, Yubo ^a   Cui, Yubao ^a   Chen, L Y ^a  

^a UNIVERSITY OF TEXAS AT SAN ANTONIO   (United States)

Author keywords

Aquaporin inhibition; Molecular dynamics; Osmotic permeation

Indexed keywords

AQUAPORIN; AQUAPORIN Z; CYSTEINE; MERCURY; MUTANT PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CHANNEL GATING; CHEMICAL BINDING; CHEMICAL INTERACTION; COMPUTER MODEL; CONCENTRATION RESPONSE; CONFORMATIONAL TRANSITION; COVALENT BOND; ESCHERICHIA COLI; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STRUCTURE; WATER PERMEABILITY; WATER TRANSPORT;

AQUAPORINS; CYSTEINE; ESCHERICHIA COLI PROTEINS; MERCURY; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MUTANT PROTEINS; WATER;

ESCHERICHIA COLI;

EID: 80455122834     PISSN: 03014622     EISSN: 18734200     Source Type: Journal    
DOI: 10.1016/j.bpc.2011.07.006     Document Type: Article

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