In vitro and in vivo modulation of ABCG2 by functionalized aurones and structurally related analogs

Biochemical Pharmacology

Volumn 82, Issue 11, 2011, Pages 1562-1571

  Sim, Hong May ^a   Wu, Chung Pu ^b   Ambudkar, Suresh V ^b   Go, Mei Lin ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

ABC transporter; ABCG2; Functionalized aurones; Multidrug resistance; Reversing agents

Indexed keywords

ADENOSINE TRIPHOSPHATASE; AURONE DERIVATIVE; BREAST CANCER RESISTANCE PROTEIN; FLAVONOID; IODINE 125; IODOARYLAZIDOPRAZOSIN; MITOXANTRONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; CELL VIABILITY; CHEMICAL STRUCTURE; CONTROLLED STUDY; CYTOMETRY; CYTOTOXICITY; DOWN REGULATION; DRUG EFFICACY; ENZYME SUBSTRATE COMPLEX; FEMALE; HUMAN; HUMAN CELL; IC 50; MODULATION; MOUSE; NONHUMAN; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; TUMOR XENOGRAFT; WESTERN BLOTTING;

ANIMALS; ANTINEOPLASTIC AGENTS; ATP-BINDING CASSETTE TRANSPORTERS; BENZOFURANS; CELL SURVIVAL; CHALCONES; CHLOROPHYLL; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; FEMALE; FLAVONES; INDANS; MICE; MICE, INBRED BALB C; MICE, NUDE; MITOXANTRONE; NEOPLASM TRANSPLANTATION; TRANSPLANTATION, HETEROLOGOUS;

EID: 80255122738     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2011.08.002     Document Type: Article

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