-
1
-
-
13344277357
-
Early neonatal death in mice homozygous for a null allele of the insulin receptor gene
-
DOI 10.1038/ng0196-106
-
Accili D, Drago J, Lee EJ, Johnson MD, Cool MH, Salvatore P, Asico LD, Jose PA, Taylor SI,Westphal H. 1996. Early neonatal death in mice homozygous for a null allele of the insulin receptor gene. Nat Genet 12:106-109 (Pubitemid 26013160)
-
(1996)
Nature Genetics
, vol.12
, Issue.1
, pp. 106-109
-
-
Accili, D.1
Drago, J.2
Lee, E.J.3
Johnson, M.D.4
Cool, M.H.5
Salvatore, P.6
Asico, L.D.7
Jose, P.A.8
Taylor, S.I.9
Westphal, H.10
-
2
-
-
0033906634
-
Structure and function of the type 1 insulin-like growth factor receptor
-
Adams TE, Epa VC, Garrett TP, Ward CW. 2000. Structure and function of the type 1 insulin-like growth factor receptor. Cell Mol Life Sci 57:1050-1093 (Pubitemid 30598754)
-
(2000)
Cellular and Molecular Life Sciences
, vol.57
, Issue.7
, pp. 1050-1093
-
-
Adams, T.E.1
Epa, V.C.2
Garrett, T.P.J.3
Ward, C.W.4
-
3
-
-
0345826131
-
The Mitogenic Action of Insulin-like Growth Factor I in Normal Human Mammary Epithelial Cells Requires the Epidermal Growth Factor Receptor Tyrosine Kinase
-
DOI 10.1074/jbc.M306156200
-
Ahmad T, Farnie G, Bundred NJ, Anderson NG. 2004. The mitogenic action of insulin-like growth factor I in normal human mammary epithelial cells requires the epidermal growth factor receptor tyrosine kinase. J Biol Chem 279:1713-1719 (Pubitemid 38084438)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.3
, pp. 1713-1719
-
-
Ahmad, T.1
Farnie, G.2
Bundred, N.J.3
Anderson, N.G.4
-
4
-
-
0028890744
-
The insulin-like growth factor i receptor: A key to tumor growth?
-
Baserga R. 1995. The insulin-like growth factor I receptor: A key to tumor growth? Cancer Res 55:249-252
-
(1995)
Cancer Res
, vol.55
, pp. 249-252
-
-
Baserga, R.1
-
5
-
-
0033920612
-
Insulin-like growth factor (IGF)-binding proteins: Interactions with IGFs and intrinsic bioactivities
-
Baxter RC. 2000. Insulin-like growth factor (IGF) binding proteins: Interactions with IGFs and intrinsic bioactivities. Am J Physiol 278:E967-E976 (Pubitemid 30439132)
-
(2000)
American Journal of Physiology - Endocrinology and Metabolism
, vol.278
, Issue.6
-
-
Baxter, R.C.1
-
6
-
-
36949021795
-
Molecular interactions in the insulin-like growth factor (IGF) axis: A surface plasmon resonance (SPR) based biosensor study
-
DOI 10.1007/s11010-007-9601-8
-
Beattie J, Phillips K, Shand JH, Szymanowska M, Flint DJ, Allan GJ. 2008. Molecular interactions in the insulin-like growth factor (IGF) axis: A surface plasmon resonance (SPR) based biosensor study. Mol Cell Biochem 307:221-236 (Pubitemid 350238664)
-
(2008)
Molecular and Cellular Biochemistry
, vol.307
, Issue.1-2
, pp. 221-236
-
-
Beattie, J.1
Phillips, K.2
Shand, J.H.3
Szymanowska, M.4
Flint, D.J.5
Allan, G.J.6
-
7
-
-
62649130113
-
IGFBP-3 and IGFBP-5 associate with the cell binding domain (CBD) of fibronectin
-
Beattie J, Kreiner M, Allan GJ, Flint DJ, Domingues D, van der Walle CF. 2009. IGFBP-3 and IGFBP-5 associate with the cell binding domain (CBD) of fibronectin. Biochem Biophys Res Commun 381:572-576
-
(2009)
Biochem Biophys Res Commun
, vol.381
, pp. 572-576
-
-
Beattie, J.1
Kreiner, M.2
Allan, G.J.3
Flint, D.J.4
Domingues, D.5
Van Der Walle, C.F.6
-
8
-
-
77954584972
-
Cross-talk between the insulin-like growth factor (IGF) axis and membrane integrins to regulate cell physiology
-
Beattie J, McIntosh L, van der Walle CF. 2010. Cross-talk between the insulin-like growth factor (IGF) axis and membrane integrins to regulate cell physiology. J Cell Physiol 224:605-611
-
(2010)
J Cell Physiol
, vol.224
, pp. 605-611
-
-
Beattie, J.1
McIntosh, L.2
Van Der Walle, C.F.3
-
9
-
-
70849120946
-
Insulin receptor isoforms and insulin receptor/insulin-like growth factor receptor hybrids in physiology and disease
-
Belfiore A, Frasca F, Pandini G, Sciacca L, Vigneri R. 2009. Insulin receptor isoforms and insulin receptor/insulin-like growth factor receptor hybrids in physiology and disease. Endocr Rev 30: 586-623
-
(2009)
Endocr Rev
, vol.30
, pp. 586-623
-
-
Belfiore, A.1
Frasca, F.2
Pandini, G.3
Sciacca, L.4
Vigneri, R.5
-
10
-
-
0027724341
-
Limited proteolysis of insulin-like growth factor binding proteiN-3 (IGFBP-3): A physiological mechanism in the regulation of IGF bioavailability
-
Binoux M, Lalou C, Lassarre C, Blat C, Hossenlopp P. 1993 Limited proteolysis of insulin-like growth factor binding proteiN-3 (IGFBP-3): A physiological mechanism in the regulation of IGF bioavailability. Adv Exp Med Biol 343:293-300 (Pubitemid 24059298)
-
(1993)
Advances in Experimental Medicine and Biology
, vol.343
, pp. 293-300
-
-
Binoux, M.1
Lalou, C.2
Lassarre, C.3
Blat, C.4
Hossenlopp, P.5
-
11
-
-
54249117292
-
Feedback mechanisms promote cooperativity for small molecule inhibitors of epidermal and insulin-like growth factor receptors
-
Buck E, Eyzaguirre A, Rosenfeld-Franklin M, Thomson S, Mulvihill M, Barr S, Brown E, OConnor M, Yao Y, Pachter J, Miglarese M, Epstein D, Iwata KK, Haley JD, Gibson NW, Ji Q-S. 2008. Feedback mechanisms promote cooperativity for small molecule inhibitors of epidermal and insulin-like growth factor receptors. Cancer Res 68:8322-8332
-
(2008)
Cancer Res
, vol.68
, pp. 8322-8332
-
-
Buck, E.1
Eyzaguirre, A.2
Rosenfeld-Franklin, M.3
Thomson, S.4
Mulvihill, M.5
Barr, S.6
Brown, E.7
Oconnor, M.8
Yao, Y.9
Pachter, J.10
Miglarese, M.11
Epstein, D.12
Iwata, K.K.13
Haley, J.D.14
Gibson, N.W.15
Ji, Q.-S.16
-
12
-
-
0038070060
-
Insulin-like growth factor binding protein proteolysis
-
DOI 10.1016/S1043-2760(03)00049-3
-
Bunn RC, Fowlkes JL. 2003. Insulin-like growth factor binding protein proteolysis. Trends Endocrinol Metab 14:176-181 (Pubitemid 36733903)
-
(2003)
Trends in Endocrinology and Metabolism
, vol.14
, Issue.4
, pp. 176-181
-
-
Bunn, R.C.1
Fowlkes, J.L.2
-
13
-
-
1942536619
-
Insulin-like growth factor binding proteiN-3 expression is associated with growth stimulation of T47D human breast cancer cells: The role of altered epidermal growth factor signaling
-
DOI 10.1210/jc.2003-030914
-
Butt AJ, Martin JL, Dickson KA, McDougall F, Firth SM, Baxter RC. 2004. Insulin-like growth factor binding proteiN-3 expression is associated with growth stimulation of T47D human breast cancer cells: The role of altered epidermal growth factor signaling. J Clin Endocrinol Metab 89:1950-1956 (Pubitemid 38507956)
-
(2004)
Journal of Clinical Endocrinology and Metabolism
, vol.89
, Issue.4
, pp. 1950-1956
-
-
Butt, A.J.1
Martin, J.L.2
Dickson, K.A.3
McDougall, F.4
Firth, S.M.5
Baxter, R.C.6
-
14
-
-
34547131835
-
A novel modulatory mechanism of transforming growth factor-β signaling through decorin and LRP-1
-
DOI 10.1074/jbc.M700243200
-
Cabello-Verrugio C, Brandan E. 2007. A novel modulatory mechanism of transforming growth factor-beta signaling through decorin and LRP-1. J Biol Chem 282:18842-18850 (Pubitemid 47100183)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.26
, pp. 18842-18850
-
-
Cabello-Verrugio, C.1
Brandan, E.2
-
15
-
-
37349131288
-
Insulin-like growth factor-I receptor, E-cadherin and αv integrin form a dynamic complex under the control of α-catenin
-
DOI 10.1002/ijc.23164
-
Canonici A, Steelant W, Rigot V, Khomitch-Baud A, Boutaghou-Cherid H, Bruyneel E, Van Roy F, Garrouste F, Pommier G, Andre F. 2008. Insulin-like growth factor-I receptor, E-cadherin and alpha v integrin form a dynamic complex under the control of alpha-catenin. Int J Cancer 122:572-582 (Pubitemid 350308948)
-
(2008)
International Journal of Cancer
, vol.122
, Issue.3
, pp. 572-582
-
-
Canonici, A.1
Steelant, W.2
Rigot, V.3
Khomitch-Baud, A.4
Boutaghou-Cherid, H.5
Bruyneel, E.6
Van Roy, F.7
Garrouste, F.8
Pommier, G.9
Andre, F.10
-
16
-
-
17944375553
-
PI3-kinase in concert with Src promotes the S-phase entry of oestradiol-stimulated MCF-7 cells
-
DOI 10.1093/emboj/20.21.6050
-
Castoria G, Migliaccio A, Bilancio A, Di Domenico M, de Falco A, Lombardi M, Fiorentino R, Varricchio L, BaroneMV, Auricchio F. 2001. PI3-kinase in concert with Src promotes the S-phase entry of oestradiol-stimulated MCF-7 cells. EMBO J 20: 6050-6059 (Pubitemid 33049280)
-
(2001)
EMBO Journal
, vol.20
, Issue.21
, pp. 6050-6059
-
-
Castoria, G.1
Migliaccio, A.2
Bilancio, A.3
Di Domenico, M.4
De Falco, A.5
Lombardi, M.6
Fiorentino, R.7
Varricchio, L.8
Barone, M.V.9
Auricchio, F.10
-
18
-
-
0038071783
-
Minireview: Integral membrane proteins that function coordinately with the insulin-like growth factor I receptor to regulate intracellular signaling
-
DOI 10.1210/en.2002-221102
-
Clemmons DR, Maile LA. 2003. Minireview: Integral membrane proteins that function coordinately with the insulin-like growth factor I receptor to regulate intracellular signaling. Endocrinology 144:1664-1670 (Pubitemid 36543301)
-
(2003)
Endocrinology
, vol.144
, Issue.5
, pp. 1664-1670
-
-
Clemmons, D.R.1
Maile, L.A.2
-
19
-
-
11244352382
-
Interaction between insulin-like growth factor-I receptor and αVβ3 integrin linked signaling pathways: Cellular responses to changes in multiple signaling inputs
-
DOI 10.1210/me.2004-0376
-
Clemmons DR, Maile LA. 2005. Interaction between insulin-like growth factor-I receptor and aVb3 integrin linked signaling pathways: Cellular responses to changes in multiple signaling inputs. Mol Endocrinol 19:1-11 (Pubitemid 40065954)
-
(2005)
Molecular Endocrinology
, vol.19
, Issue.1
, pp. 1-11
-
-
Clemmons, D.R.1
Maile, L.A.2
-
20
-
-
0027278676
-
Serum 'big insulin-like growth factor II' from patients with tumor hypoglycemia lacks normal E-domain O-linked glycosylation, a possible determinant of normal propeptide processing
-
Daughaday WH, Trivedi B, Baxter RC. 1993. Serum "big insulinlike growth factor II" from patients with tumor hypoglycemia lacks normal E-domain O-linked glycosylation, a possible determinant of normal propeptide processing. Proc Natl Acad Sci USA 90:5823-5827 (Pubitemid 23176255)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.12
, pp. 5823-5827
-
-
Daughaday, W.H.1
Trivedi, B.2
Baxter, R.C.3
-
21
-
-
0029391379
-
Role of the time factor in signaling specificity: Application to mitogenic and metabolic signaling by the insulin and insulin-like growth factor-I receptor tyrosine kinases
-
De Meyts P, Christoffersen CT, Ursø B, Wallach B, Grønskov K, Yakushiji F, Shymko RM. 1995. Role of the time factor in signaling specificity: Application to mitogenic and metabolic signaling by the insulin and insulin-like growth factor-I receptor tyrosine kinases. Metabolism 44:2-11
-
(1995)
Metabolism
, vol.44
, pp. 2-11
-
-
De Meyts, P.1
Christoffersen, C.T.2
Ursø, B.3
Wallach, B.4
Grønskov, K.5
Yakushiji, F.6
Shymko, R.M.7
-
22
-
-
30944440065
-
Differential activation of insulin receptor isoforms by insulin-like growth factors is determined by the C domain
-
DOI 10.1210/en.2005-0736
-
Denley A, Brierley GV, Carroll JM, Lindenberg A, Booker GW, Cosgrove LJ, Wallace JC, Forbes BE, Roberts CT, Jr. 2006 Differential activation of insulin receptor isoforms by insulin-like growth factors is determined by the C domain. Endocrinology 147:1029-1036 (Pubitemid 43113023)
-
(2006)
Endocrinology
, vol.147
, Issue.2
, pp. 1029-1036
-
-
Denley, A.1
Brierley, G.V.2
Carroll, J.M.3
Lindenberg, A.4
Booker, G.W.5
Cosgrove, L.J.6
Wallace, J.C.7
Forbes, B.E.8
Roberts Jr., C.T.9
-
23
-
-
0034751597
-
Insulin and IGF-1 induce different patterns of gene expression in mouse fibroblast NIH-3T3 cells: Identification by cDNA microarray analysis
-
DOI 10.1210/en.142.11.4969
-
Dupont J, Khan J, Qu BH, Metzler P, Helman L, LeRoith D. 2001 Insulin and IGF-1 induce different patterns of gene expression in mouse fibroblast NIH-3T3 cells: Identification by cDNA microarray analysis. Endocrinology 142:4969-4975 (Pubitemid 33022373)
-
(2001)
Endocrinology
, vol.142
, Issue.11
, pp. 4969-4975
-
-
Dupont, J.1
Khan, J.2
Qu, B.-H.3
Metzler, P.4
Helman, L.5
LeRoith, D.6
-
24
-
-
0346095214
-
The Insulin-like Growth Factor Axis in Cell Cycle Progression
-
DOI 10.1055/s-2004-814162
-
Dupont J, Pierre A, Froment P, Moreau C. 2003. The insulin-like growth factor axis in cell cycle progression. HormMetab Res 35: 740-750 (Pubitemid 38058178)
-
(2003)
Hormone and Metabolic Research
, vol.35
, Issue.11-12
, pp. 740-750
-
-
Dupont, J.1
Pierre, A.2
Froment, P.3
Moreau, C.4
-
25
-
-
34548856208
-
The insulin-like growth factor type 1 and insulin-like growth factor type 2/mannose-6-phosphate receptors independently regulate ERK1/2 activity in HEK293 cells
-
DOI 10.1074/jbc.M703276200
-
El-Shewy HM, Lee MH, Obeid LM, Jaffa AA, Luttrell LM. 2007 The insulin-like growth factor type 1 and insulin-like growth factor type 2/mannose-6-phosphate receptors independently regulate ERK1/2 activity in HEK293 cells. J Biol Chem 282: 26150-26157 (Pubitemid 47443807)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.36
, pp. 26150-26157
-
-
El-Shewy, H.M.1
Lee, M.-H.2
Obeid, L.M.3
Jaffa, A.A.4
Luttrell, L.M.5
-
26
-
-
0034671895
-
Growth inhibition by insulin-like growth factor-binding proteiN-3 in T47D breast cancer cells requires transforming growth factor-β (TGF-β) and the type II TGF-β receptor
-
DOI 10.1074/jbc.M006964200
-
Fanayan S, Firth SM, Butt AJ, Baxter RC. 2000. Growth inhibition by insulin-like growth factor-binding proteiN-3 in T47D breast cancer cells requires transforming growth factor-beta (TGF-b) and the type II TGF-b receptor. J Biol Chem 275: 39146-39151 (Pubitemid 32058930)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.50
, pp. 39146-39151
-
-
Fanayan, S.1
Firth, S.M.2
Butt, A.J.3
Baxter, R.C.4
-
27
-
-
0036510391
-
Signaling through the Smad pathway by insulin-like growth factor-binding proteiN-3 in breast cancer cells. Relationship to transforming growth factor-β1 signaling
-
DOI 10.1074/jbc.M108038200
-
Fanayan S, Firth SM, Baxter RC. 2002. Signaling through the Smad pathway by insulin-like growth factor binding proteiN-3 in breast cancer cells: Relationship to transforming growth factorb1 signaling. J Biol Chem 277:7255-7261 (Pubitemid 34953118)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.9
, pp. 7255-7261
-
-
Fanayan, S.1
Firth, S.M.2
Baxter, R.C.3
-
28
-
-
0036905115
-
Cellular actions of the insulin-like growth factor binding proteins
-
DOI 10.1210/er.2001-0033
-
Firth SM, Baxter RC. 2002. Cellular actions of the insulin-like growth factor binding proteins. Endocr Rev 23:824-854 (Pubitemid 35454590)
-
(2002)
Endocrine Reviews
, vol.23
, Issue.6
, pp. 824-854
-
-
Firth, S.M.1
Baxter, R.C.2
-
29
-
-
77950256025
-
Transforming growth factor-b (TGFb) receptors I/II differentially regulate TGFb1 and IGF-binding proteiN-3 mitogenic effects in the human placenta
-
Forbes K, Souquet B, Garside R, Aplin JD, Westwood M. 2010 Transforming growth factor-b (TGFb) receptors I/II differentially regulate TGFb1 and IGF-binding proteiN-3 mitogenic effects in the human placenta. Endocrinology 151:1723-1731
-
(2010)
Endocrinology
, vol.151
, pp. 1723-1731
-
-
Forbes, K.1
Souquet, B.2
Garside, R.3
Aplin, J.D.4
Westwood, M.5
-
30
-
-
0032932822
-
Insulin receptor isoform A, a newly recognized, high-affinity insulin- like growth factor II receptor in fetal and cancer cells
-
Frasca F, Pandini G, Scalia P, Sciacca L, Mineo R, Costantino A, Goldfine ID, Belfiore A, Vigneri R. 1999. Insulin receptor isoform A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells. Mol Cell Biol 19: 3278-3288 (Pubitemid 29193789)
-
(1999)
Molecular and Cellular Biology
, vol.19
, Issue.5
, pp. 3278-3288
-
-
Frasca, F.1
Pandini, G.2
Scalia, P.3
Sciacca, L.4
Mineo, R.5
Costantino, A.6
Goldfine, I.D.7
Belfiore, A.8
Vigneri, R.9
-
31
-
-
77957241580
-
The proliferating role of insulin and insulin-like growth factors in cancer
-
Gallagher EJ, LeRoith D. 2010. The proliferating role of insulin and insulin-like growth factors in cancer. Trends Endocrinol Metab 21:610-618
-
(2010)
Trends Endocrinol Metab
, vol.21
, pp. 610-618
-
-
Gallagher, E.J.1
Leroith, D.2
-
32
-
-
9444287002
-
Dual effects of IGFBP-3 on endothelial cell apoptosis and survival: Involvement of the sphingolipid signaling pathways
-
DOI 10.1096/fj.04-1618fje
-
Granata R, Trovato L, Garbarino G, Taliano M, Ponti R, Sala G, Ghidoni R, Ghigo E. 2004. Dual effects of IGFBP-3 on endothelial cell apoptosis and survival: Involvement of the sphingolipid signaling pathways. FASEB J 18:1456-1458 (Pubitemid 39561613)
-
(2004)
FASEB Journal
, vol.18
, Issue.12
, pp. 1456-1458
-
-
Granata, R.1
Trovato, L.2
Garbarino, G.3
Taliano, M.4
Ponti, R.5
Sala, G.6
Ghidoni, R.7
Ghigo, E.8
-
33
-
-
46749156706
-
Acquired resistance to EGFR tyrosine kinase inhibitors in cancer cells is mediated by loss of IGF-binding proteins
-
DOI 10.1172/JC134588
-
Guix M, Faber AC,Wang SE, Olivares MG, Song Y, Qu S, Rinehart C, Seidel B, Yee D, Arteaga CL, Engelman JA. 2008. Acquired resistance to EGFR tyrosine kinase inhibitors in cancer cells is mediated by loss of IGF-binding proteins. J Clin Invest 118: 2609-2619 (Pubitemid 351949788)
-
(2008)
Journal of Clinical Investigation
, vol.118
, Issue.7
, pp. 2609-2619
-
-
Guix, M.1
Faber, A.C.2
Wang, S.E.3
Olivares, M.G.4
Song, Y.5
Qu, S.6
Rinehart, C.7
Seidel, B.8
Yee, D.9
Arteaga, C.L.10
Engelman, J.A.11
-
34
-
-
0029862845
-
Sustained signalling from the insulin receptor after stimulation with insulin analogues exhibiting increased mitogenic potency
-
Hansen BF, Danielsen GM, Drejer K, Sørensen AR, Wiberg FC, Klein HH, Lundemose AG. 1996. Sustained signalling from the insulin receptor after stimulation with insulin analogues exhibiting increased mitogenic potency. Biochem J 315: 271-279 (Pubitemid 26113562)
-
(1996)
Biochemical Journal
, vol.315
, Issue.1
, pp. 271-279
-
-
Hansen, B.F.1
Danielsen, G.M.2
Drejer, K.3
Sorensen, A.R.4
Wiberg, F.C.5
Klein, H.H.6
Lundemose, A.G.7
-
35
-
-
0036124703
-
RACK1, an insulin-like growth factor I (IGF-I) receptor-interacting protein, modulates IGF-I-dependent integrin signaling and promotes cell spreading and contact with extracellular matrix
-
DOI 10.1128/MCB.22.7.2345-2365.2002
-
Hermanto U, Zong CS, LiW,Wang LH. 2002. RACK1, an insulinlike growth factor I (IGF-I) receptor-interacting protein, modulates IGF-I-dependent integrin signaling and promotes cell spreading and contact with extracellular matrix. Mol Cell Biol 22:2345-2365 (Pubitemid 34224638)
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.7
, pp. 2345-2365
-
-
Hermanto, U.1
Zong, C.S.2
Li, W.3
Wang, L.-H.4
-
36
-
-
40849085396
-
Substrate-bound insulin-like growth factor (IGF)-I-IGF binding protein-vitronectin-stimulated breast cell migration is enhanced by coactivation of the phosphatidylinositide 3-kinase/AKT pathway by αv-integrins and the IGF-I receptor
-
DOI 10.1210/en.2007-0740
-
Hollier BG, Kricker JA, Van Lonkhuyzen DR, Leavesley DI, Upton Z. 2008. Substrate-bound insulin-like growth factor (IGF)-IIGF binding protein-Vn-stimulated breast cell migration is enhanced by coactivation of the phosphatidylinositide 3-Kinase/ AKT pathway by alphav-integrins and the IGF-I receptor. Endocrinology 149:1075-1090 (Pubitemid 351397938)
-
(2008)
Endocrinology
, vol.149
, Issue.3
, pp. 1075-1090
-
-
Hollier, B.G.1
Kricker, J.A.2
Van Lonkhuyzen, D.R.3
Leavesley, D.I.4
Upton, Z.5
-
37
-
-
0242526800
-
1 requires LRP-1
-
DOI 10.1096/fj.03-0256com
-
Huang SS, Ling TY, Tseng WF, Huang YH, Tang FM, Leal SM, Huang JS. 2003. Cellular growth inhibition by IGFBP-3 and TGF-beta1 requires LRP-1. FASEB J 17:2068-2081 (Pubitemid 37392451)
-
(2003)
FASEB Journal
, vol.17
, Issue.14
, pp. 2068-2081
-
-
Huang, S.S.1
Ling, T.-Y.2
Tseng, W.-F.3
Huang, Y.-H.4
Tang, F.-M.5
Leal, S.M.6
Huang, J.S.7
-
38
-
-
9444297067
-
Identification of insulin receptor substrate proteins as key molecules for the TβR-V/LRP-1-mediated growth inhibitory signaling cascade in epithelial and myeloid cells
-
DOI 10.1096/fj.04-1872fje
-
Huang SS, Leal SM, Chen CL, Liu IH, Huang JS. 2004 Identification of insulin receptor substrate proteins as key molecules for the TbetaR-V/LRP-1-mediated growth inhibitory signaling cascade in epithelial and myeloid cells. FASEB J 18: 1719-1721 (Pubitemid 39561662)
-
(2004)
FASEB Journal
, vol.18
, Issue.14
, pp. 1719-1721
-
-
Shuan, S.H.1
Leal, S.M.2
Chen, C.-L.3
Liu, I.-H.4
Jung, S.H.5
-
39
-
-
0030458110
-
Regulation of insulin-like growth factor I receptor expression by the pure antiestrogen ICI 182780
-
Huynh H, Nickerson T, Pollak M, Yang X. 1996. Regulation of insulin-like growth factor I receptor expression by the pure antiestrogen ICI 182780. Clin Cancer Res 2:2037-2042 (Pubitemid 27006637)
-
(1996)
Clinical Cancer Research
, vol.2
, Issue.12
, pp. 2037-2042
-
-
Huynh, H.1
Nickerson, T.2
Pollak, M.3
Yang, X.4
-
40
-
-
3042751482
-
Insulin-like growth factor binding proteiN-3 antagonizes the effects of retinoids in myeloid leukemia cells
-
DOI 10.1182/blood-2003-07-2203
-
Ikezoe T, Tanosaki S, Krug U, Liu B, Cohen P, Taguchi H, Koeffler HP. 2004. Insulin-like growth factor binding proteiN-3 antagonizes the effects of retinoids in myeloid leukemia cells. Blood 104:237-242 (Pubitemid 38879863)
-
(2004)
Blood
, vol.104
, Issue.1
, pp. 237-242
-
-
Ikezoe, T.1
Tanosaki, S.2
Krug, U.3
Liu, B.4
Cohen, P.5
Taguchi, H.6
Koeffler, H.P.7
-
41
-
-
77956939368
-
Identification of a novel cell death receptor mediating IGFBP-3-induced anti-tumor effects in breast and prostate cancer
-
Ingermann AR, Yang YF, Han J, Mikami A, Garza AE, Mohanraj L, Fan L, Idowu M, Ware JL, Kim HS, Lee DY, Oh Y. 2010 Identification of a novel cell death receptor mediating IGFBP-3-induced anti-tumor effects in breast and prostate cancer. J Biol Chem 285:30233-30246
-
(2010)
J Biol Chem
, vol.285
, pp. 30233-30246
-
-
Ingermann, A.R.1
Yang, Y.F.2
Han, J.3
Mikami, A.4
Garza, A.E.5
Mohanraj, L.6
Fan, L.7
Idowu, M.8
Ware, J.L.9
Kim, H.S.10
Lee, D.Y.11
Oh, Y.12
-
42
-
-
0034674065
-
Estrogen receptor a rapidly activates the IGF-1 receptor pathway
-
DOI 10.1074/jbc.M910345199
-
Kahlert S, Nuedling S, van Eickels M, Vetter H, Meyer R, Grohe C. 2000. Estrogen Receptor a Rapidly Activates the IGF-1 Receptor Pathway. J Biol Chem 275:18447-18453 (Pubitemid 30414803)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.24
, pp. 18447-18453
-
-
Kahlert, S.1
Nuedling, S.2
Van Eickels, M.3
Vetter, H.4
Meyer, R.5
Grohe, C.6
-
43
-
-
0027955344
-
Essential role of tyrosine residues 1131, 1135, and 1136 of the insulin-like growth factor-I (IGF-I) receptor in IGF-I action
-
Kato H, Faria TN, Stannard B, Roberts CT, Jr, LeRoith D. 1994 Essential role of tyrosine residues 1131, 1135, and 1136 of the insulin-like growth factor-I (IGF-I) receptor in IGF-I action. Mol Endocrinol 8:40-50
-
(1994)
Mol Endocrinol
, vol.8
, pp. 40-50
-
-
Kato, H.1
Faria, T.N.2
Stannard, B.3
Roberts Jr., C.T.4
Leroith, D.5
-
44
-
-
70350719504
-
Insulin-like growth factor binding proteiN-3 mediates vascular repair by enhancing nitric oxide generation
-
Kielczewski JL, Jarajapu YP,McFarland EL, Cai J, Afzal A, Li Calzi S, Chang KH, Lydic T, Shaw LC, Busik J, Hughes J, Cardounel AJ, Wilson K, Lyons TJ, Boulton ME, Mames RN, Chan-Ling T, Grant MB. 2009. Insulin-like growth factor binding proteiN-3 mediates vascular repair by enhancing nitric oxide generation. Circ Res 105:897-905
-
(2009)
Circ Res
, vol.105
, pp. 897-905
-
-
Kielczewski, J.L.1
Jarajapu Ypmcfarland, E.L.2
Cai, J.3
Afzal, A.4
Li Calzi, S.5
Chang, K.H.6
Lydic, T.7
Shaw, L.C.8
Busik, J.9
Hughes, J.10
Cardounel, A.J.11
Wilson, K.12
Lyons, T.J.13
Boulton, M.E.14
Mames, R.N.15
Chan-Ling, T.16
Grant, M.B.17
-
45
-
-
0027157576
-
Insulin receptor autophosphorylation. II. Determination of autophosphorylation sites by chemical sequence analysis and identification of the juxtamembrane sites
-
Kohanski RA. 1993. Insulin receptor autophosphorylation. II. Determination of autophosphorylation sites by chemical sequence analysis and identification of the juxtamembrane sites. Biochemistry 32:5773-5780 (Pubitemid 23175678)
-
(1993)
Biochemistry
, vol.32
, Issue.22
, pp. 5773-5780
-
-
Kohanski, R.A.1
-
48
-
-
36549015742
-
Insulin receptor structure and its implications for the IGF-1 receptor
-
DOI 10.1016/j.sbi.2007.07.007, PII S0959440X07001066, Catalysis and Regulation /Protein
-
Lawrence MC, McKern NM, Ward CW. 2007. Insulin receptor structure and its implications for the IGF-1 receptor. Curr Opin Struct Biol 17:699-705 (Pubitemid 350180400)
-
(2007)
Current Opinion in Structural Biology
, vol.17
, Issue.6
, pp. 699-705
-
-
Lawrence, M.C.1
McKern, N.M.2
Ward, C.W.3
-
49
-
-
0030744864
-
The type V transforming growth factor β receptor is the putative insulin-like growth factor-binding protein 3 receptor
-
DOI 10.1074/jbc.272.33.20572
-
Leal SM, Liu Q, Huang SS, Huang JS. 1997. The type V transforming growth factor beta receptor is the putative insulinlike growth factor-binding protein 3 receptor. J Biol Chem 272: 20572-20576 (Pubitemid 27355615)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.33
, pp. 20572-20576
-
-
Leal, S.M.1
Liu, Q.2
Huang, S.S.3
Huang, J.S.4
-
50
-
-
0033305004
-
Enhancement of insulin-like growth factor signaling in human breast cancer: Estrogen regulation of insulin receptor substrate-1 expression in vitro and in vivo
-
Lee AV, Jackson JG, Gooch JL, Hilsenbeck SG, Coronado-Heinsohn E, Osborne CK, Yee D. 1999. Enhancement of insulin-like growth factor signaling in human breast cancer: Estrogen regulation of insulin receptor substrate-1 expression in vitro and in vivo. Mol Endocrinol 13:787-796 (Pubitemid 30645331)
-
(1999)
Molecular Endocrinology
, vol.13
, Issue.5
, pp. 787-796
-
-
Lee, A.V.1
Jackson, J.G.2
Gooch, J.L.3
Hilsenbeck, S.G.4
Coronado-Heinsohn, E.5
Osborne, C.K.6
Yee, D.7
-
51
-
-
20444461570
-
Rapid apoptosis induction by IGFBP-3 involves an insulin-like growth factor-independent nucleomitochondrial translocation of RXRα/Nur77
-
DOI 10.1074/jbc.M412757200
-
Lee KW, Ma L, Yan X, Liu B, Zhang XK, Cohen P. 2005. Rapid apoptosis induction by IGFBP-3 involves an insulin-like growth factor-independent nucleomitochondrial translocation of RXRalpha/Nur77. J Biol Chem 280:16942-16948 (Pubitemid 41389154)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.17
, pp. 16942-16948
-
-
Lee, K.-W.1
Ma, L.2
Yan, X.3
Liu, B.4
Zhang, X.-K.5
Cohen, P.6
-
52
-
-
33646355723
-
-/- mice
-
DOI 10.1093/jb/mvj039
-
Lee SH, Takahashi M, Honke K, Miyoshi E, OsumiD, Sakiyama H, Ekuni A, Wang X, Inoue S, Gu J, Kadomatsu K, Taniguchi N. 2006. Loss of core fucosylation of low-density lipoprotein receptor-related protein-1 impairs its function, leading to the upregulation of serum levels of insulin-like growth factorbinding protein 3 in Fut8-/-mice. J Biochem 139:391-398 (Pubitemid 43667103)
-
(2006)
Journal of Biochemistry
, vol.139
, Issue.3
, pp. 391-398
-
-
Lee, S.H.1
Takahashi, M.2
Honke, K.3
Miyoshi, E.4
Osumi, D.5
Sakiyama, H.6
Ekuni, A.7
Wang, X.8
Inoue, S.9
Gu, J.10
Kadomatsu, K.11
Taniguchi, N.12
-
53
-
-
34548069891
-
Contribution of the orphan nuclear receptor Nur77 to the apoptotic action of IGFBP-3
-
DOI 10.1093/carcin/bgm088
-
Lee KW, Cobb LJ, Paharkova-Vatchkova V, Liu B, Milbrandt J, Cohen P. 2007. Contribution of the orphan nuclear receptor Nur77 to the apoptotic action of IGFBP-3. Carcinogenesis 28: 1653-1658 (Pubitemid 47289026)
-
(2007)
Carcinogenesis
, vol.28
, Issue.8
, pp. 1653-1658
-
-
Lee, K.-W.1
Cobb, L.J.2
Paharkova-Vatchkova, V.3
Liu, B.4
Milbrandt, J.5
Cohen, P.6
-
54
-
-
79955959814
-
Insulin-like growth factor-binding proteiN-3 (IGFBP-3) blocks the effects of asthma by negatively regulating NF-kappaB signaling through IGFBP-3R-mediated activation of caspases
-
Lee YC, Jogie-Brahim S, Lee DY, Han J, Harada A, Murphy LJ, Oh Y. 2011. Insulin-like growth factor-binding proteiN-3 (IGFBP-3) blocks the effects of asthma by negatively regulating NF-kappaB signaling through IGFBP-3R-mediated activation of caspases. J Biol Chem 286:17898-17909
-
(2011)
J Biol Chem
, vol.286
, pp. 17898-17909
-
-
Lee, Y.C.1
Jogie-Brahim, S.2
Lee, D.Y.3
Han, J.4
Harada, A.5
Murphy, L.J.6
Oh, Y.7
-
55
-
-
50349092250
-
LDL receptor-related protein 1: Unique tissue-specific functions revealed by selective gene knockout studies
-
Lillis AP, Van Duyn LB, Murphy-Ullrich JE, Strickland DK. 2008 LDL receptor-related protein 1: Unique tissue-specific functions revealed by selective gene knockout studies. Physiol Rev 88: 887-918
-
(2008)
Physiol Rev
, vol.88
, pp. 887-918
-
-
Lillis, A.P.1
Van Duyn, L.B.2
Murphy-Ullrich, J.E.3
Strickland, D.K.4
-
56
-
-
0027496895
-
Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)
-
DOI 10.1016/0092-8674(93)90679-K
-
Liu JP, Baker J, Perkins AS, Robertson EJ, Efstratiadis A. 1993 Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r). Cell 75: 59-72 (Pubitemid 23306021)
-
(1993)
Cell
, vol.75
, Issue.1
, pp. 59-72
-
-
Liu, J.-P.1
Baker, J.2
Perkins, A.S.3
Robertson, E.J.4
Efstratiadis, A.5
-
57
-
-
0034721879
-
Direct functional interactions between insulinlike growth factor-binding proteiN-3 and retinoid X receptoralpha regulate transcriptional signaling and apoptosis
-
Liu B, Lee HY, Weinzimer SA, Powell DR, Clifford JL, Kurie JM, Cohen P. 2000. Direct functional interactions between insulinlike growth factor-binding proteiN-3 and retinoid X receptoralpha regulate transcriptional signaling and apoptosis. J Biol Chem 275:33607-33613
-
(2000)
J Biol Chem
, vol.275
, pp. 33607-33613
-
-
Liu, B.1
Lee, H.Y.2
Weinzimer, S.A.3
Powell, D.R.4
Clifford, J.L.5
Kurie, J.M.6
Cohen, P.7
-
58
-
-
0036826862
-
The αVβ3 integrin regulates insulin-like growth factor I (IGF-I) receptor phosphorylation by altering the rate of recruitment of the Src-homology 2-containing phosphotyrosine phosphatase-2 to the activated IGF-I receptor
-
DOI 10.1210/en.2002-220395
-
Maile LA, Clemmons DR. 2002. The alphaVbeta3 integrin regulates insulin-like growth factor I (IGF-I) receptor phosphorylation by altering the rate of recruitment of the Src-homology 2-containing phosphotyrosine phosphatase-2 to the activated IGF-I receptor. Endocrinology 143:4259-4264 (Pubitemid 35239556)
-
(2002)
Endocrinology
, vol.143
, Issue.11
, pp. 4259-4264
-
-
Maile, L.A.1
Clemmons, D.R.2
-
59
-
-
79951861980
-
Plasma distribution and signaling activities of IGF-II precursors
-
Marks AG, Carroll JM, Purnell JQ, Roberts CT, Jr. 2011. Plasma distribution and signaling activities of IGF-II precursors. Endocrinology 152:922-930
-
(2011)
Endocrinology
, vol.152
, pp. 922-930
-
-
Marks, A.G.1
Carroll, J.M.2
Purnell, J.Q.3
Roberts Jr., C.T.4
-
60
-
-
0034526749
-
A role for Akt in mediating the estrogenic functions of epidermal growth factor and insulin-like growth factor I
-
DOI 10.1210/en.141.12.4503
-
Martin MB, Franke TF, Stoica GE, Chambon P, Katzenellenbogen BS, Stoica BA, McLemore MS, Olivo SE, Stoica A. 2000. A role for Akt in mediating the estrogenic functions of epidermal growth factor and insulin-like growth factor I. Endocrinology 141:4503-4511 (Pubitemid 32055127)
-
(2000)
Endocrinology
, vol.141
, Issue.12
, pp. 4503-4511
-
-
Martin, M.B.1
Franke, T.F.2
Stoica, G.E.3
Chambon, P.4
Katzenellenbogen, B.S.5
Stoica, B.A.6
McLemore, M.S.7
Olivo, S.E.8
Stoica, A.9
-
61
-
-
0037474298
-
Insulin-like growth factor-binding proteiN-3 potentiates epidermal growth factor action in MCF-10A mammary epithelial cells. Involvement of p44/42 and p38 mitogen-activated protein kinases
-
DOI 10.1074/jbc.M210739200
-
Martin JL, Weenink SM, Baxter RC. 2003. Insulin-like growth factor-binding proteiN-3 potentiates epidermal growth factor action in MCF-10A mammary epithelial cells. Involvement of p44/42 and p38 mitogen-activated protein kinases. J Biol Chem 278:2969-2976 (Pubitemid 36801203)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.5
, pp. 2969-2976
-
-
Martin, J.L.1
Weenink, S.M.2
Baxter, R.C.3
-
62
-
-
70350018274
-
Potentiation of growth factor signaling by insulin-like growth factor-binding proteiN-3 in breast epithelial cells requires sphingosine kinase activity
-
Martin JL, Lin MZ,McGowan EM, Baxter RC. 2009. Potentiation of growth factor signaling by insulin-like growth factor-binding proteiN-3 in breast epithelial cells requires sphingosine kinase activity. J Biol Chem 284:25542-25552
-
(2009)
J Biol Chem
, vol.284
, pp. 25542-25552
-
-
Martin, J.L.1
Lin Mzmcgowan, E.M.2
Baxter, R.C.3
-
63
-
-
0037663541
-
Estrogen receptor-α regulates the degradation of insulin receptor substrates 1 and 2 in breast cancer cells
-
DOI 10.1038/sj.onc.1206436
-
Morelli C, Garofalo C, Bartucci M, Surmacz E. 2003. Estrogen receptor-[alpha] regulates the degradation of insulin receptor substrates 1 and 2 in breast cancer cells. Oncogene 22: 4007-4016 (Pubitemid 36819641)
-
(2003)
Oncogene
, vol.22
, Issue.26
, pp. 4007-4016
-
-
Morelli, C.1
Garofalo, C.2
Bartucci, M.3
Surmacz, E.4
-
64
-
-
33750571170
-
Heterodimerization of insulin-like growth factor receptor/epidermal growth factor receptor and induction of survivin expression counteract the antitumor action of erlotinib
-
DOI 10.1158/0008-5472.CAN-06-1684
-
Morgillo F, Woo JK, Kim ES, Hong WK, Lee H-Y. 2006 Heterodimerization of insulin-like growth factor receptor/ epidermal growth factor receptor and induction of survivin expression counteract the antitumor action of Erlotinib. Cancer Res 66:10100-10111 (Pubitemid 44672064)
-
(2006)
Cancer Research
, vol.66
, Issue.20
, pp. 10100-10111
-
-
Morgillo, F.1
Woo, J.K.2
Kim, E.S.3
Hong, W.K.4
Lee, H.-Y.5
-
65
-
-
0035090634
-
Limited redundancy of survival signals from the type 1 insulin-like growth factor receptor
-
DOI 10.1210/en.142.3.1073
-
Navarro M, Baserga R. 2001. Limited redundancy of survival signals from the type 1 insulin-like growth factor receptor. Endocrinology 142:1073-1081 (Pubitemid 32202816)
-
(2001)
Endocrinology
, vol.142
, Issue.3
, pp. 1073-1081
-
-
Navarro, M.1
Baserga, R.2
-
66
-
-
0029946896
-
Involution of the lactating mammary gland is inhibited by the IGF system in a transgenic mouse model
-
Neuenschwander S, Schwartz A, Wood TL, Roberts CJ, Henninghausen L, LeRoith D. 1996. Involution of the lactating mammary gland is inhibited by the IGF system in a transgenic mouse model. J Clin Invest 97:2225-2232 (Pubitemid 26165711)
-
(1996)
Journal of Clinical Investigation
, vol.97
, Issue.10
, pp. 2225-2232
-
-
Neuenschwander, S.1
Schwartz, A.2
Wood, T.L.3
Roberts Jr., C.T.4
Henninghausen, L.5
LeRoith, D.6
-
67
-
-
0031028245
-
Identification of domains of the insulin-like growth factor I receptor that are required for protection from apoptosis
-
OConnor R, Kauffmann-Zeh A, Liu Y, Lehar S, Evan GI, Baserga R, Blattler WA. 1997. Identification of domains of the insulinlike growth factor I receptor that are required for protection from apoptosis. Mol Cell Biol 17:427-435 (Pubitemid 26425632)
-
(1997)
Molecular and Cellular Biology
, vol.17
, Issue.1
, pp. 427-435
-
-
O'Connor, R.1
Kauffmann-Zeh, A.2
Liu, Y.3
Lehar, S.4
Evan, G.I.5
Baserga, R.6
Blattler, W.A.7
-
68
-
-
0142180099
-
Differential Gene Expression Induced by Insulin and Insulin-like Growth Factor-II through the Insulin Receptor Isoform A
-
DOI 10.1074/jbc.M304980200
-
Pandini G, Medico E, Conte E, Sciacca L, Vigneri R, Belfiore A. 2003. Differential gene expression induced by insulin and insulin-like growth factor-II through the insulin receptor isoform A. J Biol Chem 278:42178-42189 (Pubitemid 37310484)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.43
, pp. 42178-42189
-
-
Pandini, G.1
Medico, E.2
Conte, E.3
Sciacca, L.4
Vigneri, R.5
Belfiore, A.6
-
69
-
-
2442444905
-
The Role of the Acid-Labile Subunit in Regulating Insulin-Like Growth Factor Transport across Human Umbilical Vein Endothelial Cell Monolayers
-
DOI 10.1210/jc.2003-031880
-
Payet LD, Firth SM, Baxter RC. 2004. The role of the acid-labile subunit in regulating insulin-like growth factor transport across human umbilical vein endothelial cell monolayers. J Clin Endocrinol Metab 89:2382-2389 (Pubitemid 38619879)
-
(2004)
Journal of Clinical Endocrinology and Metabolism
, vol.89
, Issue.5
, pp. 2382-2389
-
-
Payet, L.D.1
Firth, S.M.2
Baxter, R.C.3
-
70
-
-
0032827420
-
Multiple signaling pathways of the insulin-like growth factor 1 receptor in protection from apoptosis
-
Peruzzi F, Prisco M, Dews M, Salomoni P, Grassilli E, Romano G, Calabretta B, Baserga R. 1999. Multiple signaling pathways of the insulin-like growth factor 1 receptor in protection from apoptosis. Mol Cell Biol 19:7203-7215 (Pubitemid 29441900)
-
(1999)
Molecular and Cellular Biology
, vol.19
, Issue.10
, pp. 7203-7215
-
-
Peruzzi, F.1
Prisco, M.2
Dews, M.3
Salomoni, P.4
Grassilli, E.5
Romano, G.6
Calabretta, B.7
Baserga, R.8
-
71
-
-
33847321518
-
The EGF receptor interacts with the type 1 IGF receptor and regulates its stability
-
DOI 10.1016/j.bbrc.2007.02.012, PII S0006291X07002823
-
Riedemann J, Takiguchi M, Sohail M, Macaulay VM. 2007. The EGF receptor interacts with the type 1 IGF receptor and regulates its stability. Biochem Biophys Res Commun 355: 707-714 (Pubitemid 46330209)
-
(2007)
Biochemical and Biophysical Research Communications
, vol.355
, Issue.3
, pp. 707-714
-
-
Riedemann, J.1
Takiguchi, M.2
Sohail, M.3
Macaulay, V.M.4
-
72
-
-
0029980569
-
Correlation of insulin-like growth factor-binding proteiN-3 messenger RNA with protein expression in primary breast cancer tissues: Detection of higher levels in tumors with poor prognostic features
-
DOI 10.1093/jnci/88.9.601
-
Rocha RL, Hilsenbeck SG, Jackson JG, Lee AV, Figueroa JA, Yee D. 1996. Correlation of insulin-like growth factor-binding proteiN-3 messenger RNAwith protein expression in primary breast cancer tissues: Detection of higher levels in tumors with poor prognostic features. J Natl Cancer Inst 88:601-606 (Pubitemid 26137582)
-
(1996)
Journal of the National Cancer Institute
, vol.88
, Issue.9
, pp. 601-606
-
-
Rocha, R.L.1
Hilsenbeck, S.G.2
Jackson, J.G.3
Lee, A.V.4
Figueroa, J.A.5
Yee, D.6
-
73
-
-
0034698096
-
Transactivation of the EGF receptor mediates IGF-1-stimulated Shc phosphorylation and ERK1/2 activation in COS-7 cells
-
DOI 10.1074/jbc.M002915200
-
Roudabush FL, Pierce KL, Maudsley S, Khan KD, Luttrell LM. 2000. Transactivation of the EGF receptor mediates IGF-1-stimulated shc phosphorylation and ERK1/2 activation in COS-7 cells. J Biol Chem 275:22583-22589 (Pubitemid 30621851)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.29
, pp. 22583-22589
-
-
Roudabush, F.L.1
Pierce, K.L.2
Maudsley, S.3
Khan, K.D.4
Luttrell, L.M.5
-
74
-
-
24944587144
-
Insulin-like growth factor binding protein-2 binding to extracellular matrix plays a critical role in neuroblastoma cell proliferation, migration, and invasion
-
DOI 10.1210/en.2005-0467
-
Russo VC, Schutt BS, Andaloro E, Ymer SI, Hoeflich A, Ranke MB, Bach LA, Werther GA. 2005. Insulin-like growth factor binding protein-2 binding to extracellular matrix plays a critical role in neuroblastoma cell proliferation, migration, and invasion. Endocrinology 146:4445-4455 (Pubitemid 41324043)
-
(2005)
Endocrinology
, vol.146
, Issue.10
, pp. 4445-4455
-
-
Russo, V.C.1
Schutt, B.S.2
Andaloro, E.3
Ymer, S.I.4
Hoeflich, A.5
Ranke, M.B.6
Bach, L.A.7
Werther, G.A.8
-
75
-
-
69949177417
-
The direct binding of insulin-like growth factor-1 (IGF-1) to integrin alphaVbeta3 is involved in IGF-1 signaling
-
Saegusa J, Yamaji S, Ieguchi K,Wu C-Y, Lam KS, Liu F-T, Takada YK, Takada Y. 2009. The direct binding of insulin-like growth factor-1 (IGF-1) to integrin alphaVbeta3 is involved in IGF-1 signaling. J Biol Chem 284:24106-24114
-
(2009)
J Biol Chem
, vol.284
, pp. 24106-24114
-
-
Saegusa, J.1
Yamaji, S.2
Ieguchi Kwu, C.-Y.3
Lam, K.S.4
Liu, F.-T.5
Takada, Y.K.6
Takada, Y.7
-
76
-
-
33846874575
-
The role of the IGF system in cancer growth and metastasis: Overview and recent insights
-
DOI 10.1210/er.2006-0001
-
Samani AA, Yakar S, LeRoithD, Brody P. 2007. The role of the IGF system in cancer growth and metastasis: Overview and recent insights. Endocr Rev 28:20-47 (Pubitemid 46220849)
-
(2007)
Endocrine Reviews
, vol.28
, Issue.1
, pp. 20-47
-
-
Samani, A.A.1
Yakar, S.2
LeRoith, D.3
Brodt, P.4
-
77
-
-
34548391901
-
Molecular basis of the interaction between IGFBP-3 and retinoid X receptor: Role in modulation of RAR-signaling
-
DOI 10.1016/j.abb.2007.06.013, PII S0003986107003037
-
Schedlich LJ, Graham LD, OHan MK,Muthukaruppan A, Yan X, Firth SM, Baxter RC. 2007. Molecular basis of the interaction between IGFBP-3 and retinoid X receptor: Role in modulation of RAR-signaling. Arch Biochem Biophys 465:359-369 (Pubitemid 47362000)
-
(2007)
Archives of Biochemistry and Biophysics
, vol.465
, Issue.2
, pp. 359-369
-
-
Schedlich, L.J.1
Graham, L.D.2
O'Han, M.K.3
Muthukaruppan, A.4
Yan, X.5
Firth, S.M.6
Baxter, R.C.7
-
78
-
-
34948886604
-
Insulin-like growth factor binding protein-5 interacts with the vitamin D receptor and modulates the vitamin D response in osteoblasts
-
DOI 10.1210/me.2006-0558
-
Schedlich LJ, Muthukaruppan A, OHan MK, Baxter RC. 2007 Insulin-like growth factor binding protein-5 interacts with the vitamin D receptor and modulates the vitamin D response in osteoblasts. Mol Endocrinol 21:2378-2390 (Pubitemid 47529352)
-
(2007)
Molecular Endocrinology
, vol.21
, Issue.10
, pp. 2378-2390
-
-
Schedlich, L.J.1
Muthukaruppan, A.2
O'Han, M.K.3
Baxter, R.C.4
-
79
-
-
2542582263
-
The role of the M6P/IGF-II receptor in cancer: Tumor suppression or garbage disposal?
-
DOI 10.1055/s-2004-814477
-
Scott CD, Firth SM. 2004. The role of the M6P/IGF-II receptor in cancer: Tumor suppression or garbage disposal? Horm Metab Res 36:261-271 (Pubitemid 38703784)
-
(2004)
Hormone and Metabolic Research
, vol.36
, Issue.5
, pp. 261-271
-
-
Scott, C.D.1
Firth, S.M.2
-
80
-
-
64949122409
-
Insulin-like growth factor-binding proteiN-3 in breast cancer: Analysis with tissue microarray
-
Sheen-Chen SM, Zhang H, Huang CC, Tang RP. 2009. Insulin-like growth factor-binding proteiN-3 in breast cancer: Analysis with tissue microarray. Anticancer Res 29:1131-1135
-
(2009)
Anticancer Res
, vol.29
, pp. 1131-1135
-
-
Sheen-Chen, S.M.1
Zhang, H.2
Huang, C.C.3
Tang, R.P.4
-
81
-
-
33748367666
-
Structural basis for the inhibition of insulin-like growth factors by insulin-like growth factor-binding proteins
-
DOI 10.1073/pnas.0605652103
-
Sitar T, Popowicz GM, Siwanowicz I, Huber R, Holak TA. 2006 Structural basis for the inhibition of insulin-like growth factors by insulin-like growth factor-binding proteins. Proc Natl Acad Sci USA 103:13028-13033 (Pubitemid 44338911)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.35
, pp. 13028-13033
-
-
Sitar, T.1
Popowicz, G.M.2
Siwanowicz, I.3
Huber, R.4
Holak, T.A.5
-
82
-
-
0036137605
-
Linkage of rapid estrogen action to MAPK activation by ERα-Shc association and Shc pathway activation
-
DOI 10.1210/me.16.1.116
-
Song RXD,McPherson RA, Adam L, Bao Y, Shupnik M, Kumar R, Santen RJ. 2002. Linkage of rapid estrogen action to MAPK activation by ERa-Shc association and Shc pathway activation. Mol Endocrinol 16:116-127 (Pubitemid 34044502)
-
(2002)
Molecular Endocrinology
, vol.16
, Issue.1
, pp. 116-127
-
-
Song, R.X.-D.1
McPherson, R.A.2
Adam, L.3
Bao, Y.4
Shupnik, M.5
Kumar, R.6
Santen, R.J.7
-
83
-
-
0025131648
-
Receptors for insulin and insulin-like growth factor-I can form hybrid dimers
-
Soos MA, Whittaker J, Lammers R, Ullrich A, Siddle K. 1990 Receptors for insulin and insulin-like growth factor-I can form hybrid dimers. Characterisation of hybrid receptors in transfected cells. Biochem J 270:383-390
-
(1990)
Characterisation of Hybrid Receptors in Transfected Cells. Biochem J
, vol.270
, pp. 383-390
-
-
Soos, M.A.1
Whittaker, J.2
Lammers, R.3
Ullrich, A.4
Siddle, K.5
-
84
-
-
0036231180
-
Requirement for IGF-I in epidermal growth factor-mediated cell cycle progression of mammary epithelial cells
-
DOI 10.1210/en.143.5.1872
-
Stull MA, Richert MM, Loladze AV,Wood TL. 2002. Requirement for IGF-I in epidermal growth factor-mediated cell cycle progression of mammary epithelial cells. Endocrinology 143: 1872-1879 (Pubitemid 34415903)
-
(2002)
Endocrinology
, vol.143
, Issue.5
, pp. 1872-1879
-
-
Stull, M.A.1
Richert, M.M.2
Loladze, A.V.3
Wood, T.L.4
-
85
-
-
0033305195
-
Prolonged activation of ERK2 by epidermal growth factor and other growth factors requires a functional insulin-like growth factor 1 receptor
-
Swantek JL, Baserga R. 1999. Prolonged activation of ERK2 by epidermal growth factor and other growth factors requires a functional insulin-like growth factor 1 receptor. Endocrinology 140:3163-3169 (Pubitemid 30650632)
-
(1999)
Endocrinology
, vol.140
, Issue.7
, pp. 3163-3169
-
-
Swantek, J.L.1
Baserga, R.2
-
86
-
-
0141731299
-
Insulin-like growth factor-1 induces adhesion and migration in human multiple myeloma cells via activation of β1-integrin and phosphatidylinositol 3′-kinase/AKT signaling
-
Tai Y-T, Podar K, Catley L, Tseng Y-H, Akiyama M, Shringarpure R, Burger R, Hideshima T, Chauhan D, Mitsiades N, Richardson P, Munshi NC, Kahn CR, Mitsiades C, Anderson KC. 2003. Insulin-like growth factor-1 induces adhesion and migration in human multiple myeloma cells via activation of beta1-integrin and phosphatidylinositol 3-kinase/AKT signaling. Cancer Res 63:5850-5858 (Pubitemid 37187484)
-
(2003)
Cancer Research
, vol.63
, Issue.18
, pp. 5850-5858
-
-
Tai, Y.-T.1
Podar, K.2
Catley, L.3
Tseng, Y.-H.4
Akiyama, M.5
Shringarpure, R.6
Burger, R.7
Hideshima, T.8
Chauhan, D.9
Mitsiades, N.10
Richardson, P.11
Munshi, N.C.12
Kahn, C.R.13
Mitsiades, C.14
Anderson, K.C.15
-
87
-
-
79953303497
-
A systems view of epithelial-mesenchymal transition signaling states
-
Thomson S, Petti F, Sujka-Kwok I, Mercado P, Bean J, Monaghan M, Seymour SL, Argast GM, Epstein DM, Haley JD. 2011 A systems view of epithelial- mesenchymal transition signaling states. Clin Exp Metastasis 28:137-155
-
(2011)
Clin Exp Metastasis
, vol.28
, pp. 137-155
-
-
Thomson, S.1
Petti, F.2
Sujka-Kwok, I.3
Mercado, P.4
Bean, J.5
Monaghan, M.6
Seymour, S.L.7
Argast, G.M.8
Epstein, D.M.9
Haley, J.D.10
-
88
-
-
0030659122
-
Igf-I variants which bind poorly to IGF-binding proteins show more potent and prolonged hypoglycaemic action than native IGF-I in pigs and marmoset monkeys
-
DOI 10.1677/joe.0.1550377
-
Tomas FM, Walton PE, Dunshea FR, Ballard FJ. 1997. IGF-I variants which bind poorly to IGF-binding proteins show more potent and prolonged hypoglycaemic action than native IGF-I in pigs and marmoset monkeys. J Endocrinol 155:377-386 (Pubitemid 27475833)
-
(1997)
Journal of Endocrinology
, vol.155
, Issue.2
, pp. 377-386
-
-
Tomas, F.M.1
Walton, P.E.2
Dunshea, F.R.3
Ballard, F.J.4
-
89
-
-
77949741721
-
Toward a comprehensive neurobiology of IGF-I
-
Torres-Aleman I. 2010. Toward a comprehensive neurobiology of IGF-I. Dev Neurobiol 70:384-396
-
(2010)
Dev Neurobiol
, vol.70
, pp. 384-396
-
-
Torres-Aleman, I.1
-
90
-
-
0032723877
-
Differences in signaling properties of the cytoplasmic domains of the insulin receptor and insulinlike growth factor receptor in 3T3-L1 adipocytes
-
Urso B, Cope DL, Kalloo-Hosein HE, Hayward AC, Whitehead JP, ORahilly S, Siddle K. 1999. Differences in signaling properties of the cytoplasmic domains of the insulin receptor and insulinlike growth factor receptor in 3T3-L1 adipocytes. J Biol Chem 274:30864-30873
-
(1999)
J Biol Chem
, vol.274
, pp. 30864-30873
-
-
Urso, B.1
Cope, D.L.2
Kalloo-Hosein, H.E.3
Hayward, A.C.4
Whitehead, J.P.5
Orahilly, S.6
Siddle, K.7
-
91
-
-
0028902772
-
Induction of autocrine epidermal growth factor receptor ligands in human keratinocytes by insulin/ insulin-like growth factor-1
-
Vardy DA, Kari C, Lazarus GS, Jensen PJ, Zilberstein A, Plowman GD, Rodeck U. 1995. Induction of autocrine epidermal growth factor receptor ligands in human keratinocytes by insulin/ insulin-like growth factor-1. J Cell Physiol 163:257-265
-
(1995)
J Cell Physiol
, vol.163
, pp. 257-265
-
-
Vardy, D.A.1
Kari, C.2
Lazarus, G.S.3
Jensen, P.J.4
Zilberstein, A.5
Plowman, G.D.6
Rodeck, U.7
-
92
-
-
0035970567
-
Roads to survival: Insulin-like growth factor-1 signaling pathways in cardiac muscle
-
Wang PH. 2001. Roads to survival: Insulin-like growth factor-1 signaling pathways in cardiac muscle. Circ Res 88:552-554 (Pubitemid 32275789)
-
(2001)
Circulation Research
, vol.88
, Issue.6
, pp. 552-554
-
-
Wang, P.H.1
-
93
-
-
4143092587
-
Sphingosine 1-phosphate cross-activates the Smad signaling cascade and mimics transforming growth factor-β-induced cell responses
-
DOI 10.1074/jbc.M312091200
-
Xin C, Ren S, Kleuser B, Shabahang S, Eberhardt W, Radeke H, Schafer-Korting M, Pfeilschifter J, Huwiler A. 2004. Sphingosine 1-phosphate cross-activates the Smad signaling cascade and mimics transforming growth factor-beta-induced cell responses. J Biol Chem 279:35255-35262 (Pubitemid 39100522)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.34
, pp. 35255-35262
-
-
Xin, C.1
Ren, S.2
Kleuser, B.3
Shabahang, S.4
Eberhardt, W.5
Radeke, H.6
Schafer-Korting, M.7
Pfeilschifter, J.8
Huwiler, A.9
-
94
-
-
11144234526
-
Role of N- and C-terminal residues of insulin-like growth factor (IGF)-binding proteiN-3 in regulating IGF complex formation and receptor activation
-
DOI 10.1074/jbc.M409345200
-
Yan X, Forbes BE, McNeil KA, Baxter RC, Firth SM. 2004. Role of N-and C-terminal residues of insulin-like growth factor (IGF)-binding proteiN-3 in regulating IGF complex formation and receptor activation. J Biol Chem 279:53232-53240 (Pubitemid 40051826)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.51
, pp. 53232-53240
-
-
Yan, X.1
Forbes, B.E.2
McNeil, K.A.3
Baxter, R.C.4
Firth, S.M.5
-
95
-
-
70350277706
-
Activity of human pregnancy insulin-like growth factor binding proteiN-3: Determination by reconstituting recombinant complexes
-
Yan X, Payet LD, Baxter RC, Firth SM. 2009. Activity of human pregnancy insulin-like growth factor binding proteiN-3: Determination by reconstituting recombinant complexes. Endocrinology 150:4968-4976
-
(2009)
Endocrinology
, vol.150
, pp. 4968-4976
-
-
Yan, X.1
Payet, L.D.2
Baxter, R.C.3
Firth, S.M.4
|