Igf-I variants which bind poorly to IGF-binding proteins show more potent and prolonged hypoglycaemic action than native IGF-I in pigs and marmoset monkeys

Journal of Endocrinology

Volumn 155, Issue 2, 1997, Pages 377-386

  Tomas, F M ^a   Walton, P E ^a,c   Dunshea, F R ^b   Ballard, F J ^a  

^a Div of Hlth Sciences and Nutrition   (Australia)

^b VIC INSTITUTE OF ANIMAL SCIENCE   (Australia)

^c Diagnostic Systems Laboratories Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; RECOMBINANT SOMATOMEDIN C; SOMATOMEDIN BINDING PROTEIN; SOMATOMEDIN C; SOMATOMEDIN C DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DOSE RESPONSE; DRUG POTENCY; HYPOGLYCEMIA; INTRAVENOUS DRUG ADMINISTRATION; MALE; MONKEY; NONHUMAN; PRIORITY JOURNAL; SWINE;

AMINO ACIDS; ANALYSIS OF VARIANCE; ANIMALS; AREA UNDER CURVE; BLOOD GLUCOSE; CALLITHRIX; DOSE-RESPONSE RELATIONSHIP, DRUG; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS; INSULIN-LIKE GROWTH FACTOR I; MALE; PEPTIDE FRAGMENTS; PROTEIN BINDING; RECOMBINANT PROTEINS; SWINE; TIME FACTORS;

EID: 0030659122     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.0.1550377     Document Type: Article

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