Nifedipine synergizes with calcium in activating the calcium sensing receptor, suppressing the expression of thymidylate synthase and survivin and promoting sensitivity to fluorouracil in human colon carcinoma cells

Molecular Carcinogenesis

Volumn 50, Issue 12, 2011, Pages 922-930

  Liu, Guangming ^a   Hu, Xin ^a   Premkumar, Louis ^a   Chakrabarty, Subhas ^a  

^a SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Calcium sensing receptor; Drug sensitivity; Human colon carcinoma cells; Nifedipine

Indexed keywords

CALCIUM; CALCIUM SENSING RECEPTOR; FLUOROURACIL; NIFEDIPINE; SMALL INTERFERING RNA; SURVIVIN; THYMIDYLATE SYNTHASE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; COLON CARCINOMA; CONTROLLED STUDY; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG POTENTIATION; DRUG SENSITIVITY; DRUG TARGETING; HUMAN; HUMAN CELL; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANTIMETABOLITES, ANTINEOPLASTIC; CALCIUM; CELL LINE, TUMOR; CELL PROLIFERATION; COLONIC NEOPLASMS; DRUG SYNERGISM; FLUOROURACIL; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; GTP-BINDING PROTEINS; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; NIFEDIPINE; RECEPTORS, CALCIUM-SENSING; RNA INTERFERENCE; RNA, SMALL INTERFERING; THYMIDYLATE SYNTHASE;

EID: 80155180739     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.20752     Document Type: Article

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