메뉴 건너뛰기




Volumn 301, Issue 5, 2011, Pages

Ongoing ingestive behavior is rapidly suppressed by a preabsorptive, intestinal "bitter taste" cue

Author keywords

Chemoreceptor; Cholecystokinin; Denatonium benzoate; Food learning; Gastrointestinal

Indexed keywords

DENATONIUM BENZOATE; DEVAZEPIDE; LITHIUM CHLORIDE; SACCHARIN SODIUM; SODIUM CHLORIDE;

EID: 80155165105     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00344.2011     Document Type: Article
Times cited : (17)

References (53)
  • 1
    • 74249110599 scopus 로고    scopus 로고
    • Post-oral infusion sites that support glucose-conditioned flavor preferences in rats
    • Ackroff K, Yiin YM, Sclafani A. Post-oral infusion sites that support glucose-conditioned flavor preferences in rats. Physiol Behav 99: 402-411, 2010.
    • (2010) Physiol Behav , vol.99 , pp. 402-411
    • Ackroff, K.1    Yiin, Y.M.2    Sclafani, A.3
  • 2
    • 0032814858 scopus 로고    scopus 로고
    • Comparison of the postprandial release of peptide YY and proglucagonderived peptides in the rat
    • Anini Y, Fu-Cheng X, Cuber JC, Kervran A, Chariot J, Roz C. Comparison of the postprandial release of peptide YY and proglucagonderived peptides in the rat. Pflügers Arch 438: 299-306, 1999.
    • (1999) Pflügers Arch , vol.438 , pp. 299-306
    • Anini, Y.1    Fu-Cheng, X.2    Cuber, J.C.3    Kervran, A.4    Chariot, J.5    Roz, C.6
  • 3
    • 33847749522 scopus 로고    scopus 로고
    • Effects of cholecystokin-8s in the nucleus tractus solitaries of vagally deafferented rats
    • Baptista V, Browning KN, Travagli RA. Effects of cholecystokin-8s in the nucleus tractus solitaries of vagally deafferented rats. Am J Physiol Regul Integr Comp Physiol 292: R1092-R1100, 2007.
    • (2007) Am J Physiol Regul Integr Comp Physiol , vol.292
    • Baptista, V.1    Browning, K.N.2    Travagli, R.A.3
  • 4
    • 33845865790 scopus 로고    scopus 로고
    • Taste-signaling proteins are coexpressed in solitary intestinal epithelial cells
    • Bezençon C, le Coutre J, Damak S. Taste-signaling proteins are coexpressed in solitary intestinal epithelial cells. Chem Senses 32: 41-49, 2007.
    • (2007) Chem Senses , vol.32 , pp. 41-49
    • Bezençon, C.1    le Coutre, J.2    Damak, S.3
  • 5
    • 48249128056 scopus 로고    scopus 로고
    • Murine intestinal cells expressing Trpm5 are mostly brush cells and express markers of neuronal and inflammatory cells
    • Bezençon C, Fürholz A, Raymond F, Mansourian R, Métairon S, Le Coutre J, Damak S. Murine intestinal cells expressing Trpm5 are mostly brush cells and express markers of neuronal and inflammatory cells. J Comp Neurol 509: 514-525, 2008.
    • (2008) J Comp Neurol , vol.509 , pp. 514-525
    • Bezençon, C.1    Fürholz, A.2    Raymond, F.3    Mansourian, R.4    Métairon, S.5    le Coutre, J.6    Damak, S.7
  • 6
    • 0029941718 scopus 로고    scopus 로고
    • Type A CCK receptors mediate satiety effects of intestinal nutrients
    • Brenner LA, Ritter RC. Type A CCK receptors mediate satiety effects of intestinal nutrients. Pharmacol Biochem Behav 54: 625-631, 1996.
    • (1996) Pharmacol Biochem Behav , vol.54 , pp. 625-631
    • Brenner, L.A.1    Ritter, R.C.2
  • 9
    • 0032802624 scopus 로고    scopus 로고
    • Reduced sensitivity to the satiation effect of intestinal oleate in rats adapted to high-fat diet
    • Covasa M, Ritter RC. Reduced sensitivity to the satiation effect of intestinal oleate in rats adapted to high-fat diet. Am J Physiol Regul Integr Comp Physiol 277: R279-R285, 1999.
    • (1999) Am J Physiol Regul Integr Comp Physiol , vol.277
    • Covasa, M.1    Ritter, R.C.2
  • 10
    • 0034735740 scopus 로고    scopus 로고
    • Reduced hindbrain and enteric neuronal response to intestinal oleate in rats maintained on high-fat diet
    • Covasa M, Grahn J, Ritter RC. Reduced hindbrain and enteric neuronal response to intestinal oleate in rats maintained on high-fat diet. Auton Neurosci 84: 8-18, 2000.
    • (2000) Auton Neurosci , vol.84 , pp. 8-18
    • Covasa, M.1    Grahn, J.2    Ritter, R.C.3
  • 11
    • 0034901237 scopus 로고    scopus 로고
    • Attenuated satiation response to intestinal nutrients in rats that do not express CCK-A receptors
    • Covasa M, Ritter RC. Attenuated satiation response to intestinal nutrients in rats that do not express CCK-A receptors. Peptides 22: 1339-1348, 2001.
    • (2001) Peptides , vol.22 , pp. 1339-1348
    • Covasa, M.1    Ritter, R.C.2
  • 12
    • 78649870133 scopus 로고    scopus 로고
    • Deficits in gastrointestinal responses controlling food intake and body weight
    • Covasa M. Deficits in gastrointestinal responses controlling food intake and body weight. Am J Physiol Regul Integr Comp Physiol 299: R1423-R1439, 2010.
    • (2010) Am J Physiol Regul Integr Comp Physiol , vol.299
    • Covasa, M.1
  • 13
    • 79957859217 scopus 로고    scopus 로고
    • Impaired intestinal afferent nerve satiety signaling and vagal afferent excitability in diet induced obesity in the mouse
    • Daly DM, Park SJ, Valinsky WC, Beyak MJ. Impaired intestinal afferent nerve satiety signaling and vagal afferent excitability in diet induced obesity in the mouse. J Physiol 589: 2857-2870, 2011.
    • (2011) J Physiol , vol.589 , pp. 2857-2870
    • Daly, D.M.1    Park, S.J.2    Valinsky, W.C.3    Beyak, M.J.4
  • 14
    • 14644415512 scopus 로고    scopus 로고
    • Expression of sweet taste receptors of the T1R family in the intestinal tract and enteroendocrine cells
    • Dyer J, Salmon KS, Zibrik L, Shirazi-Beechey SP. Expression of sweet taste receptors of the T1R family in the intestinal tract and enteroendocrine cells. Biochem Soc Trans 33: 302-305, 2005.
    • (2005) Biochem Soc Trans , vol.33 , pp. 302-305
    • Dyer, J.1    Salmon, K.S.2    Zibrik, L.3    Shirazi-Beechey, S.P.4
  • 15
    • 0032476122 scopus 로고    scopus 로고
    • The role of endogenous cholecystokinin in the sensory transduction of luminal nutrient signals in the rat jejunum
    • Eastwood C, Maubach K, Kirkup AJ, Grundy D. The role of endogenous cholecystokinin in the sensory transduction of luminal nutrient signals in the rat jejunum. Neurosci Lett 254: 145-148, 1998.
    • (1998) Neurosci Lett , vol.254 , pp. 145-148
    • Eastwood, C.1    Maubach, K.2    Kirkup, A.J.3    Grundy, D.4
  • 16
    • 0026510891 scopus 로고
    • Glucagon-like peptide-I cells in the gastrointestinal tract and pancreas of rat, pig, and man
    • Eissele R, Göke R, Weichhardt U, Fehmann HC, Arnold R, Göke B. Glucagon-like peptide-I cells in the gastrointestinal tract and pancreas of rat, pig, and man. Eur J Clin Invest 22: 283-291, 1992.
    • (1992) Eur J Clin Invest , vol.22 , pp. 283-291
    • Eissele, R.1    Göke, R.2    Weichhardt, U.3    Fehmann, H.C.4    Arnold, R.5    Göke, B.6
  • 17
    • 40749098019 scopus 로고    scopus 로고
    • Intragastric infusion of denatonium conditions flavor aversions and delays gastric emptying in rodents
    • Glendinning JI, Yiin YM, Ackroff K, Sclafani A. Intragastric infusion of denatonium conditions flavor aversions and delays gastric emptying in rodents. Physiol Behav 93: 757-765, 2008.
    • (2008) Physiol Behav , vol.93 , pp. 757-765
    • Glendinning, J.I.1    Yiin, Y.M.2    Ackroff, K.3    Sclafani, A.4
  • 18
    • 38149028292 scopus 로고    scopus 로고
    • Role of CCK1 and Y2 receptors in activation of hindbrain neurons induced by intragastric administration of bitter taste receptor ligands
    • Hao S, Sternini C, Raybould HE. Role of CCK1 and Y2 receptors in activation of hindbrain neurons induced by intragastric administration of bitter taste receptor ligands. Am J Physiol Regul Integr Comp Physiol 294: R33-R38, 2008.
    • (2008) Am J Physiol Regul Integr Comp Physiol , vol.294
    • Hao, S.1    Sternini, C.2    Raybould, H.E.3
  • 19
    • 64149086122 scopus 로고    scopus 로고
    • Central fos expression and conditioned flavor avoidance in rats following intragastric administration of bitter taste receptor ligands
    • Hao S, Dulake M, Espero E, Sternini C, Raybould HE, Rinaman L. Central fos expression and conditioned flavor avoidance in rats following intragastric administration of bitter taste receptor ligands. Am J Physiol Regul Integr Comp Physiol 296: R528-R536, 2009.
    • (2009) Am J Physiol Regul Integr Comp Physiol , vol.296
    • Hao, S.1    Dulake, M.2    Espero, E.3    Sternini, C.4    Raybould, H.E.5    Rinaman, L.6
  • 20
    • 77949266522 scopus 로고    scopus 로고
    • T1R3 is expressed in brush cells and ghrelin-producing cells of murine stomach
    • Hass N, Schwarzenbacher K, Breer H. T1R3 is expressed in brush cells and ghrelin-producing cells of murine stomach. Cell Tissue Res 339: 493-504, 2010.
    • (2010) Cell Tissue Res , vol.339 , pp. 493-504
    • Hass, N.1    Schwarzenbacher, K.2    Breer, H.3
  • 21
    • 27744514129 scopus 로고    scopus 로고
    • CCK and 5-HT act synergistically to suppress food intake through simultaneous activation of CCK-1 and 5-HT-3 receptors
    • Hayes MR, Covasa M. CCK and 5-HT act synergistically to suppress food intake through simultaneous activation of CCK-1 and 5-HT-3 receptors. Peptides 26: 2322-2330, 2005.
    • (2005) Peptides , vol.26 , pp. 2322-2330
    • Hayes, M.R.1    Covasa, M.2
  • 22
    • 0029908546 scopus 로고    scopus 로고
    • Taste receptor-like cells in the rat gut identified by expression of a-gustducin
    • Hofer D, Puschel B, Drenckhahn D. Taste receptor-like cells in the rat gut identified by expression of a-gustducin. Proc Natl Acad Sci USA 93: 6631-6634, 1996.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 6631-6634
    • Hofer, D.1    Puschel, B.2    Drenckhahn, D.3
  • 24
    • 0033975270 scopus 로고    scopus 로고
    • Nutrient tasting and signaling mechanisms in the gut. IV. There is more to taste than meets the tongue
    • Katz DB, Nicolelis MA, Simon SA. Nutrient tasting and signaling mechanisms in the gut. IV. There is more to taste than meets the tongue. Am J Physiol Gastrointest Liver Physiol 278: G6-G9, 2000.
    • (2000) Am J Physiol Gastrointest Liver Physiol , vol.278
    • Katz, D.B.1    Nicolelis, M.A.2    Simon, S.A.3
  • 25
    • 0034668861 scopus 로고    scopus 로고
    • Glossopharyngeal nerve regeneration is essential for the complete recovery of quinine-stimulated oromotor rejection behaviors and central patterns of neuronal activity in the nucleus of the solitary tract in the rat
    • King CT, Garcea M, Spector AC. Glossopharyngeal nerve regeneration is essential for the complete recovery of quinine-stimulated oromotor rejection behaviors and central patterns of neuronal activity in the nucleus of the solitary tract in the rat. J Neurosci 20: 8426-8434, 2000.
    • (2000) J Neurosci , vol.20 , pp. 8426-8434
    • King, C.T.1    Garcea, M.2    Spector, A.C.3
  • 26
    • 70349560878 scopus 로고    scopus 로고
    • Taste signaling elements expressed in gut enteroendocrine cells regulate nutrient-responsive secretion of gut hormones
    • Kokrashvili Z, Mosinger B, Margolskee RF. Taste signaling elements expressed in gut enteroendocrine cells regulate nutrient-responsive secretion of gut hormones. Am J Clin Nutr 90: 822S-825S, 2009.
    • (2009) Am J Clin Nutr , vol.90
    • Kokrashvili, Z.1    Mosinger, B.2    Margolskee, R.F.3
  • 27
    • 0029782197 scopus 로고    scopus 로고
    • Pancreatic secretion evoked by cholecystokinin and non-cholecystokinin-dependent duodenal stimuli via vagal afferent fibres in the rat
    • Li Y, Owyang C. Pancreatic secretion evoked by cholecystokinin and non-cholecystokinin-dependent duodenal stimuli via vagal afferent fibres in the rat. J Physiol 494: 773-782, 1996.
    • (1996) J Physiol , vol.494 , pp. 773-782
    • Li, Y.1    Owyang, C.2
  • 29
    • 0020413519 scopus 로고
    • Flavor-toxicosis learning: Tests of 3 hypotheses of long delay learning
    • Lindberg MA, Beggs AL, Chezik DD, Ray D. Flavor-toxicosis learning: Tests of 3 hypotheses of long delay learning. Physiol Behav 29: 439-442, 1982.
    • (1982) Physiol Behav , vol.29 , pp. 439-442
    • Lindberg, M.A.1    Beggs, A.L.2    Chezik, D.D.3    Ray, D.4
  • 30
    • 34347236558 scopus 로고    scopus 로고
    • Sweet taste receptors in rat small intestine stimulate glucose absorption through apical GLUT2
    • Mace OJ, Affleck J, Patel N, Kellett GL. Sweet taste receptors in rat small intestine stimulate glucose absorption through apical GLUT2. J Physiol 582: 379-392, 2007.
    • (2007) J Physiol , vol.582 , pp. 379-392
    • Mace, O.J.1    Affleck, J.2    Patel, N.3    Kellett, G.L.4
  • 32
    • 0018104714 scopus 로고
    • Acquisition of learned taste aversion following bilateral subdiaphragmatic vagotomy in rats
    • Martin JR, Chenga FY, Novin D. Acquisition of learned taste aversion following bilateral subdiaphragmatic vagotomy in rats. Physiol Behav 21: 13-17, 1978.
    • (1978) Physiol Behav , vol.21 , pp. 13-17
    • Martin, J.R.1    Chenga, F.Y.2    Novin, D.3
  • 33
    • 24144448018 scopus 로고    scopus 로고
    • Concurrent conditioned taste aversion: A learning mechanism based on rapid neural versus flexible humoral processing of visceral noxious substances
    • Mediavilla C, Molina F, Puerto A. Concurrent conditioned taste aversion: A learning mechanism based on rapid neural versus flexible humoral processing of visceral noxious substances. Neurosci Biobehav Rev 29: 1107-1118, 2005.
    • (2005) Neurosci Biobehav Rev , vol.29 , pp. 1107-1118
    • Mediavilla, C.1    Molina, F.2    Puerto, A.3
  • 34
    • 0020130661 scopus 로고
    • Cholecystokinin suppresses food intake by inhibiting gastric emptying
    • Moran TH, McHugh PR. Cholecystokinin suppresses food intake by inhibiting gastric emptying. Am J Physiol Regul Integr Comp Physiol 242: R491-R497, 1982.
    • (1982) Am J Physiol Regul Integr Comp Physiol , vol.242
    • Moran, T.H.1    McHugh, P.R.2
  • 36
    • 0028338447 scopus 로고
    • Integration of postprandial function in the proximal gastrointestinal tract: Role of CCK and sensory pathways
    • Raybould HE, Lloyd KCK. Integration of postprandial function in the proximal gastrointestinal tract: Role of CCK and sensory pathways. Ann NY Acad Sci 713: 143-156, 1994.
    • (1994) Ann NY Acad Sci , vol.713 , pp. 143-156
    • Raybould, H.E.1    Lloyd, K.C.K.2
  • 37
    • 0014088807 scopus 로고
    • Small intestinal glucose transport: Proximal-distal kinetic gradients
    • Rider AK, Schedl HP, Nokes G, Shining S. Small intestinal glucose transport: Proximal-distal kinetic gradients. J Gen Physiol 50: 1173-1182, 1967.
    • (1967) J Gen Physiol , vol.50 , pp. 1173-1182
    • Rider, A.K.1    Schedl, H.P.2    Nokes, G.3    Shining, S.4
  • 38
    • 0017076882 scopus 로고
    • Bait shyness: Avoidance of the taste without escape from the illness in rats
    • Rusiniak KW, Garcia J, Hankins WG. Bait shyness: Avoidance of the taste without escape from the illness in rats. J Comp Physiol Psychol 90: 460-467, 1976.
    • (1976) J Comp Physiol Psychol , vol.90 , pp. 460-467
    • Rusiniak, K.W.1    Garcia, J.2    Hankins, W.G.3
  • 39
    • 0018777422 scopus 로고
    • Contribution of naso-oral and post-ingestional factors in taste-averson learning in the rat
    • Schneider K, Wothe K. Contribution of naso-oral and post-ingestional factors in taste-averson learning in the rat. Behav Neural Bio 25: 30-38, 1979.
    • (1979) Behav Neural Bio , vol.25 , pp. 30-38
    • Schneider, K.1    Wothe, K.2
  • 40
    • 0037308812 scopus 로고    scopus 로고
    • Selective effects of vagal deafferentation and celiac-superior mesenteric ganglionectomy on the reinforcing and satiating action of intestinal nutrients
    • Sclafani A, Ackroff K, Schwartz GJ. Selective effects of vagal deafferentation and celiac-superior mesenteric ganglionectomy on the reinforcing and satiating action of intestinal nutrients. Physiol Behav 78: 285-294, 2003.
    • (2003) Physiol Behav , vol.78 , pp. 285-294
    • Sclafani, A.1    Ackroff, K.2    Schwartz, G.J.3
  • 42
    • 0029655821 scopus 로고    scopus 로고
    • The direct and indirect controls of meal size
    • Smith GP. The direct and indirect controls of meal size. Neurosci Biobehav Rev 20: 41-46, 1996.
    • (1996) Neurosci Biobehav Rev , vol.20 , pp. 41-46
    • Smith, G.P.1
  • 43
    • 0036522960 scopus 로고    scopus 로고
    • Rats fail to discriminate quinine from denatonium: Implications for the neural coding of bitter-tasting compounds
    • Spector AC, Kopka SL. Rats fail to discriminate quinine from denatonium: Implications for the neural coding of bitter-tasting compounds. J Neurosci 22: 1937-1941, 2002.
    • (2002) J Neurosci , vol.22 , pp. 1937-1941
    • Spector, A.C.1    Kopka, S.L.2
  • 44
    • 79960687712 scopus 로고    scopus 로고
    • The functional involvement of gut-expressed sweet taste receptors in glucose-stimulated secretion of glucagon-like peptide-1 (GLP-1) and peptide YY (PYY)
    • Steinert RE, Gerspach AC, Gutmann H, Asarian L, Drewe J, Beglinger C. The functional involvement of gut-expressed sweet taste receptors in glucose-stimulated secretion of glucagon-like peptide-1 (GLP-1) and peptide YY (PYY). Clin Nutr 30: 524-532, 2011.
    • (2011) Clin Nutr , vol.30 , pp. 524-532
    • Steinert, R.E.1    Gerspach, A.C.2    Gutmann, H.3    Asarian, L.4    Drewe, J.5    Beglinger, C.6
  • 45
    • 33847078811 scopus 로고    scopus 로고
    • Taste receptors in the gastrointestinal tract. IV Functional implications of bitter taste receptors in gastrointestinal chemosensing
    • Sternini C. Taste receptors in the gastrointestinal tract. IV Functional implications of bitter taste receptors in gastrointestinal chemosensing. Am J Physiol Gastrointest Liver Physiol 292: G457-G461, 2007.
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.292
    • Sternini, C.1
  • 48
    • 33846069854 scopus 로고    scopus 로고
    • Comparison of nutritive and nonnutritive stimuli in intestinal and oral conditioned taste aversion paradigms
    • Tracy AL, Davidson TL. Comparison of nutritive and nonnutritive stimuli in intestinal and oral conditioned taste aversion paradigms. Behav Neurosci 120: 1268-1278, 2006.
    • (2006) Behav Neurosci , vol.120 , pp. 1268-1278
    • Tracy, A.L.1    Davidson, T.L.2
  • 50
    • 0037133261 scopus 로고    scopus 로고
    • Expression of bitter taste receptors of the T2R family in the gastrointestinal tract and enteroendocrine STC-1 cells
    • Wu SV, Rozengurt N, Yang M, Young SH, Sinnett-Smith J, Rozengurt E. Expression of bitter taste receptors of the T2R family in the gastrointestinal tract and enteroendocrine STC-1 cells. Proc Natl Acad Sci USA 99: 2392-2397, 2002.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 2392-2397
    • Wu, S.V.1    Rozengurt, N.2    Yang, M.3    Young, S.H.4    Sinnett-Smith, J.5    Rozengurt, E.6
  • 51
    • 0015705065 scopus 로고
    • Effects of glucose on feeding in relation to routes of entry
    • Yin TH, Tsai CT. Effects of glucose on feeding in relation to routes of entry. J Comp Physiol Psychol 85: 258-264, 1973.
    • (1973) J Comp Physiol Psychol , vol.85 , pp. 258-264
    • Yin, T.H.1    Tsai, C.T.2
  • 52
    • 79951725107 scopus 로고    scopus 로고
    • Comparative expression of hexose transporters (SGLT1, GLUT1, GLUT2, and GLUT5) throughout the mouse gastrointestinal tract
    • Yoshikawa T, Inoue R, Matsumoto M, Yajima T, Ushida K, Iwanaga T. Comparative expression of hexose transporters (SGLT1, GLUT1, GLUT2, and GLUT5) throughout the mouse gastrointestinal tract. Histochem Cell Biol 135: 183-94, 2011.
    • (2011) Histochem Cell Biol , vol.135 , pp. 183-194
    • Yoshikawa, T.1    Inoue, R.2    Matsumoto, M.3    Yajima, T.4    Ushida, K.5    Iwanaga, T.6
  • 53
    • 34547615157 scopus 로고    scopus 로고
    • Learned flavor preferences induced by intragastric administration of rewarding nutrients: Role of capsaicinsensitive vagal afferent fibers
    • Zafra MA, Molina F, Puerto A. Learned flavor preferences induced by intragastric administration of rewarding nutrients: Role of capsaicinsensitive vagal afferent fibers. Am J Physiol Regul Integr Comp Physiol 293: R635-R641, 2007.
    • (2007) Am J Physiol Regul Integr Comp Physiol , vol.293
    • Zafra, M.A.1    Molina, F.2    Puerto, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.