Complex modulation of peptidolytic activity of cathepsin D by sphingolipids

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1811, Issue 12, 2011, Pages 1097-1104

  Žebrakovská, Iva ^a,b   Máša, Martin ^a   Srp, Jaroslav ^a,b   Horn, Martin ^a   Vávrová, Kateřina ^c   Mareš, Michael ^a  

^a INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

^b CHARLES UNIVERSITY   (Czech Republic)

^c Charles University in Prague Faculty of Pharmacy   (Czech Republic)

Author keywords

Activation; Cathepsin D; Enzyme regulation; Inhibition; Phospholipid; Sphingolipid

Indexed keywords

CATHEPSIN D; CERAMIDE; SPHINGOLIPID; SPHINGOSINE;

ARTICLE; CONCENTRATION (PARAMETERS); ENZYME ACTIVATION; ENZYMOLOGY; FLUORESCENCE RESONANCE ENERGY TRANSFER; FRAGMENTATION REACTION; HUMAN; INTRACELLULAR SIGNALING; MODULATION; PEPTIDOLYTIC ACTIVITY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION;

APOPTOSIS; BINDING SITES; CATHEPSIN D; CERAMIDES; FLUORESCENCE POLARIZATION; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMANS; KINETICS; NEOPLASMS; PHOSPHORYLATION; PROTEIN BINDING; PROTEOLYSIS; SIGNAL TRANSDUCTION; SPHINGOSINE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 80155161349     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2011.09.005     Document Type: Article

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