Lipothioureas as lipids for gene transfection: A review

Pharmaceuticals

Volumn 4, Issue 10, 2011, Pages 1381-1399

  Breton, Marie ^a   Leblond, Jeanne ^b   Tranchant, Isabelle ^c   Scherman, Daniel ^d   Bessodes, Michel ^d   Herscovici, Jean ^d   Mignet, Nathalie ^d  

^a INSTITUT GUSTAVE ROUSSY   (France)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c DIF   (France)

^d Centre National de la Recherche Scientifique   (France)

Author keywords

DNA; Gene therapy; Lipoplexes; Lipothiourea; Thiourea lipids; Transfection

Indexed keywords

DIPALMITOYLPHOSPHATIDYLCHOLINE; DNA; LIPOPLEX; LIPOSOME; LIPOTHIOUREA DERIVATIVE; MACROGOL; SMALL INTERFERING RNA; THIOUREA DERIVATIVE; UNCLASSIFIED DRUG;

COMPLEX FORMATION; DRUG DETERMINATION; DRUG DNA INTERACTION; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HYDROGEN BOND; HYDROPHILICITY; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO STUDY; INTERNALIZATION; LIGHT SCATTERING; LIPOSOMAL DELIVERY; MOLECULAR INTERACTION; MOLECULAR WEIGHT; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NONVIRAL GENE THERAPY; NUCLEAR MAGNETIC RESONANCE; PARTICLE SIZE; PHYSICAL CHEMISTRY; PROCESS OPTIMIZATION; RADIATION SCATTERING; REVIEW; STRUCTURE ACTIVITY RELATION; TRANSMISSION ELECTRON MICROSCOPY; VALIDATION PROCESS; ZETA POTENTIAL;

EID: 80055083497     PISSN: None     EISSN: 14248247     Source Type: Journal    
DOI: 10.3390/ph4101381     Document Type: Review

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