Paxillin enables attachment-independent tyrosine phosphorylation of focal adhesion kinase and transformation by RAS

Journal of Biological Chemistry

Volumn 286, Issue 44, 2011, Pages 37932-37944

  Wade, Ramon ^a,b   Brimer, Nicole ^a   Lyons, Charles ^a   Vande Pol, Scott ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b NovelMed Therapeutics Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTER PROTEINS; CARBOXYL-TERMINAL; CELL ATTACHMENTS; CELL MIGRATION; COLONY FORMATION; DOCKING SITES; EXTRACELLULAR MATRICES; FOCAL ADHESION KINASE; LIM DOMAIN; MULTIPLE DOCKING; ONCOGENIC TRANSFORMATION; PAXILLIN; TYROSINE PHOSPHORYLATION;

ADHESION; AMINO ACIDS; ANCHORAGES (FOUNDATIONS); CELL CULTURE; CELL PROLIFERATION; CELLS; DOCKING; ENZYMES; SIGNAL TRANSDUCTION;

PHOSPHORYLATION;

ADAPTOR PROTEIN; DOCKING PROTEIN; FOCAL ADHESION KINASE; GIT1 PROTEIN; HIC5 PROTEIN; LD4 PROTEIN; LD5 PROTEIN; LIM PROTEIN; PAXILLIN; TUBULIN; TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CELL ADHESION; CELL MIGRATION; CELL PROLIFERATION; COLONY FORMATION; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; FIBROBLAST; MALIGNANT TRANSFORMATION; ONCOGENE RAS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ACTINS; ANIMALS; CELL ADHESION; CELL PROLIFERATION; CYTOSKELETAL PROTEINS; CYTOSKELETON; DNA-BINDING PROTEINS; ENZYME ACTIVATION; FIBROBLASTS; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIM DOMAIN PROTEINS; MICE; MUTATION; PAXILLIN; PHOSPHORYLATION; RAS PROTEINS; SIGNAL TRANSDUCTION; TYROSINE;

EID: 80055066706     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.294504     Document Type: Article

References (46)

1. Zimerman, B., Volberg, T., and Geiger, B. (2004) Cell Motil. Cytoskeleton 58, 143-159
2. Hehlgans, S., Haase, M., and Cordes, N. (2007) Biochim. Biophys. Acta 1775, 163-180
3. Deakin, N. O., and Turner, C. E. (2008) J. Cell Sci. 121, 2435-2444
4. Webb, D. J., Brown, C. M., and Horwitz, A. F. (2003) Curr. Opin. Cell Biol. 15, 614-620
5. Webb, D. J., Donais, K., Whitmore, L. A., Thomas, S. M., Turner, C. E., Parsons, J. T., and Horwitz, A. F. (2004) Nat. Cell Biol. 6, 154-161
6. Brown, M. C., and Turner, C. E. (2004) Physiol. Rev. 84, 1315-1339
7. Vallés, A. M., Beuvin, M., and Boyer, B. (2004) J. Biol. Chem. 279, 44490-44496
8. Nikolopoulos, S. N., and Turner, C. E. (2000) J. Cell Biol. 151, 1435-1448
9. Nikolopoulos, S. N., and Turner, C. E. (2001) J. Biol. Chem. 276, 23499-23505
10. Turner, C. E., Brown, M. C., Perrotta, J. A., Riedy, M. C., Nikolopoulos, S. N., McDonald, A. R., Bagrodia, S., Thomas, S., and Leventhal, P. S. (1999) J. Cell Biol. 145, 851-863
11. Wade, R., and Vande Pol, S. (2006) Biochem. J. 393, 565-573
12. Tong, X., and Howley, P. M. (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 4412-4417
13. Vande Pol, S. B., Brown, M. C., and Turner, C. E. (1998) Oncogene 16, 43-52
14. Wade, R., Brimer, N., and Vande Pol, S. (2008) J. Virol. 82, 5962-5966
15. Brown, M. C., Perrotta, J. A., and Turner, C. E. (1996) J. Cell. Biol. 135, 1109-1123
16. Shen, Y., Schneider, G., Cloutier, J. F., Veillette, A., and Schaller, M. D. (1998) J. Biol. Chem. 273, 6474-6481
17. Côté, J. F., Turner, C. E., and Tremblay, M. L. (1999) J. Biol. Chem. 274, 20550-20560
18. Jamieson, J. S., Tumbarello, D. A., Hallé, M., Brown, M. C., Tremblay, M. L., and Turner, C. E. (2005) J. Cell Sci. 118, 5835-5847
19. Shibanuma, M., Mashimo, J., Kuroki, T., and Nose, K. (1994) J. Biol. Chem. 269, 26767-26774
20. Tumbarello, D. A., and Turner, C. E. (2007) J. Cell. Physiol. 211, 736 -747
21. Dong, J. M., Lau, L. S., Ng, Y. W., Lim, L., and Manser, E. (2009) Biochem. J. 418, 173-184
22. Heitzer, M. D., and DeFranco, D. B. (2006) Cancer Res. 66, 7326-7333
23. Ili, D., Furuta, Y., Kanazawa, S., Takeda, N., Sobue, K., Nakatsuji, N., Nomura, S., Fujimoto, J., Okada, M., and Yamamoto, T. (1995) Nature 377, 539-544
24. Parsons, J. T. (2003) J. Cell Sci. 116, 1409-1416
25. Mitra, S. K., Hanson, D. A., and Schlaepfer, D. D. (2005) Nat. Rev. Mol. Cell Biol. 6, 56-68
26. Hanks, S. K., Ryzhova, L., Shin, N. Y., and Brábek, J. (2003) Front. Biosci. 8, d982-d996
27. Wade, R., Bohl, J., and Vande Pol, S. (2002) Oncogene 21, 96-107
28. Hagel, M., George, E. L., Kim, A., Tamimi, R., Opitz, S. L., Turner, C. E., Imamoto, A., and Thomas, S. M. (2002) Mol. Cell. Biol. 22, 901-915
29. Bohl, J., Das, K., Dasgupta, B., and Vande Pol, S. B. (2000) Virology 271, 163-170
30. Tumbarello, D. A., Brown, M. C., Hetey, S. E., and Turner, C. E. (2005) J. Cell Sci. 118, 4849-4863
31. Renshaw, M. W., Price, L. S., and Schwartz, M. A. (1999) J. Cell Biol. 147, 611-618
32. Zhang, Z. M., Simmerman, J. A., Guibao, C. D., and Zheng, J. J. (2008) J. Biol. Chem. 283, 18685-18693
33. McLean, G. W., Carragher, N. O., Avizienyte, E., Evans, J., Brunton, V. G., and Frame, M. C. (2005) Nat. Rev Cancer 5, 505-515
34. Siesser, P. M., and Hanks, S. K. (2006) Clin. Cancer Res. 12, 3233-3237
35. MacPherson, I., and Montagnier, L. (1964) Virology 23, 291-294
36. Stoker, M., O'Neill, C., Berryman, S., and Waxman, V. (1968) Int. J. Cancer 3, 683-693
37. Shin, S. I., Freedman, V. H., Risser, R., and Pollack, R. (1975) Proc. Natl. Acad. Sci. 72, 4435-4439
38. Freedman, V. H., and Shin, S. I. (1974) Cell 3, 355-359
39. Malumbres, M., and Barbacid, M. (2003) Nat. Rev. Cancer 3, 459-465
40. Avraamides, C., Bromberg, M. E., Gaughan, J. P., Thomas, S. M., Tsygankov, A. Y., and Panetti, T. S. (2007) Am. J. Physiol. Heart Circ. Physiol. 293, H193-H203
41. Nishiya, N., Tachibana, K., Shibanuma, M., Mashimo, J. I., and Nose, K. (2001) Mol. Cell. Biol. 21, 5332-5345
42. Fujimoto, N., Yeh, S., Kang, H. Y., Inui, S., Chang, H. C., Mizokami, A., and Chang, C. (1999) J. Biol. Chem. 274, 8316-8321
43. Shibanuma, M., Kim-Kaneyama, J. R., Sato, S., and Nose, K. (2004) J. Cell. Biochem. 91, 633-645
44. Drori, S., Girnun, G. D., Tou, L., Szwaya, J. D., Mueller, E., Xia, K., Shivdasani, R. A., and Spiegelman, B. M. (2005) Genes Dev. 19, 362-375
45. Wang, H., Song, K., Sponseller, T. L., and Danielpour, D. (2005) J. Biol. Chem. 280, 5154-5162
46. Wang, H., Song, K., Krebs, T. L., Yang, J., and Danielpour, D. (2008) Oncogene 27, 6791-6805