Paxillin nuclear-cytoplasmic localization is regulated by phosphorylation of the LD4 motif: Evidence that nuclear paxillin promotes cell proliferation

Biochemical Journal

Volumn 418, Issue 1, 2009, Pages 173-184

  Dong, Jing Ming ^a   Lau, Lei Shong ^a   Ng, Yuen Wai ^a   Lim, Louis ^b   Manser, Ed ^a  

^a INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Cell proliferation; GRK interacting ARFGAP (GIT1); H19; Nuclear cytoplasm shuttle; Paxillin

Indexed keywords

ADHESION KINASE; ADHESION PROTEINS; ADP-RIBOSYLATION FACTORS; CELL SURFACE RECEPTORS; COMPLEX COMPONENTS; CYTOPLASMIC LOCALIZATION; DNA SYNTHESIS; EXCHANGE FACTORS; G-PROTEIN COUPLED RECEPTORS; GRK-INTERACTING ARFGAP (GIT1); GTPASE-ACTIVATING PROTEIN; H19; IN-CELL; LIM DOMAIN; NUCLEAR EXPORT; NUCLEAR EXPORT SIGNALS; NUCLEAR-CYTOPLASM SHUTTLE; OVER-EXPRESSION; P-21 ACTIVATED KINASE; PAXILLIN; REAL-TIME PCR;

CELL ADHESION; CELL PROLIFERATION; CHEMICAL ACTIVATION; LADDER NETWORKS; NUCLEIC ACIDS; PERSONAL COMPUTERS; PHOSPHORYLATION; PROTEINS; SIGNAL TRANSDUCTION;

ADHESION;

ADENOSINE DIPHOSPHATE RIBOSYLATION FACTOR; CELL SURFACE RECEPTOR; DNA; FOCAL ADHESION KINASE; FOCAL ADHESION KINASE 1; G PROTEIN COUPLED RECEPTOR KINASE; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; HYDROGEN PEROXIDE INDUCIBLE PROTEIN 5; LIM KINASE; P21 ACTIVATED KINASE 1; PAXILLIN; RNA H19; SERINE; THYROID HORMONE RECEPTOR INTERACTING 6 PROTEIN; UNCLASSIFIED DRUG; ZYXIN; LEPTOMYCIN B; UNSATURATED FATTY ACID;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CELL MOTILITY; CELL NUCLEUS; CELL PROLIFERATION; CELL STRAIN 3T3; CELL STRAIN COS7; CONTROLLED STUDY; CYTOPLASM; DNA SYNTHESIS; FOCAL ADHESION; GENE LOCUS; GENE OVEREXPRESSION; HELA CELL; HUMAN CELL; NONHUMAN; NUCLEAR EXPORT SIGNAL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; ACTIVE TRANSPORT; ANIMAL; CELL LINE; CERCOPITHECUS; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; PHOSPHORYLATION;

ACTIVE TRANSPORT, CELL NUCLEUS; AMINO ACID MOTIFS; ANIMALS; CELL LINE; CELL NUCLEUS; CELL PROLIFERATION; CERCOPITHECUS AETHIOPS; CYTOPLASM; FATTY ACIDS, UNSATURATED; FOCAL ADHESIONS; GENE EXPRESSION REGULATION; HUMANS; PAXILLIN; PHOSPHORYLATION;

EID: 59849115232     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20080170     Document Type: Article

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