The reductionist paradox: Are the laws of chemistry and physics sufficient for the discovery of new drugs?

Journal of Computer-Aided Molecular Design

Volumn 25, Issue 8, 2011, Pages 699-708

  Maggiora, Gerald M ^a  

^a UNIVERSITY OF ARIZONA   (United States)

Author keywords

Biological reductionism; Drugs; Emergent properties; Hierarchy

Indexed keywords

BIOLOGICAL REDUCTIONISM; DRUG; DRUG DISCOVERY RESEARCHES; DRUG RESEARCH; EMERGENT PROPERTY; HIERARCHY; INTER-RELATIONSHIPS; MULTIPLE TARGETS; PHYSICS RESEARCH; RESEARCH FOCUS;

BIOLOGICAL SYSTEMS;

BIOLOGICAL REDUCTIONISM; BIOPHYSICS; COMPUTER ANALYSIS; CONCEPTUAL FRAMEWORK; DRUG DEVELOPMENT; DRUG RESEARCH; MATHEMATICAL MODEL; MOLECULAR BIOLOGY; POLYPHARMACY; PRIORITY JOURNAL; REVIEW; SYSTEMS BIOLOGY;

EID: 80055065804     PISSN: 0920654X     EISSN: 15734951     Source Type: Journal    
DOI: 10.1007/s10822-011-9447-8     Document Type: Review

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