Microwave-based reaction screening: Tandem retro-Diels-Alder/Diels-Alder cycloadditions of o-quinol dimers

Journal of Organic Chemistry

Volumn 76, Issue 21, 2011, Pages 8944-8954

  Dong, Suwei ^a   Cahill, Katharine J ^b   Kang, Moon Il ^c   Colburn, Nancy H ^c   Henrich, Curtis J ^c   Wilson, Jennifer A ^c   Beutler, John A ^c   Johnson, Richard P ^b   Porco, John A ^a  

^a Boston University   (United States)

^b Univ of New Hampshire   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATOR PROTEIN-1; BIOLOGICAL EVALUATION; COMPUTATIONAL STUDIES; CYCLOADDITIONS; CYCLOADDUCTS; DIASTEREOSELECTIVE; DIELS-ALDER CYCLOADDITIONS; MICROWAVE SYSTEMS; ONCOGENIC TRANSCRIPTION; TRANSITION STATE;

CYCLOADDITION; TRANSCRIPTION FACTORS;

MICROWAVE IRRADIATION;

1 HYDROXY 1 METHYL 6 (4 METHYLPENT 3 EN 1 YL) 4 (PROPAN 2 YL) 4A,5,8,8A TETRAHYDRONAPHTHALEN 2 (1H) ONE; 1 HYDROXY 1,6,7 TRIMETHYL 4 (PROPAN 2 YL) 4A,5,8,8A TETRAHYDRONAPHTHALEN 2 (1H) ONE; 3 HYDROXY 3 METHYL 6 PHENYL 7 (PROPAN 2 YL)BICYCLO(2.2.2)OCTA 5,7 DIEN 2 ONE; 3 HYDROXY 3 METHYL 7 (2 PHENYLETHENYL) 6 (PROPAN 2 YL)BICYCLO(2.2.2)OCT 5 EN 2 ONE; 3 HYDROXY 7 (4 METHYOXY)PHENYL 3 METHYL 6 (PROPAN 2 YL)BICYCLO(2.2.2)OCT 5 EN 2 ONE; ANTINEOPLASTIC AGENT; BICYCLOOCTENONE; DIMER; DIMETHYL 7 HYDROXY 7 METHYL 8 OXO 5 (PROPAN 2 YL)BICYCLO(2.2.2)OCTA 2,5 DIENE 2,3 DICARBOXYLATE; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ARTICLE; BIOLOGICAL ACTIVITY; BIOTRANSFORMATION; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; CYCLOADDITION; DENSITY FUNCTIONAL THEORY; DIASTEREOISOMER; DIELS ALDER REACTION; MICROWAVE RADIATION; NUCLEAR MAGNETIC RESONANCE; PROTEIN ANALYSIS; PROTON TRANSPORT; SCREENING; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

CATALYSIS; CYCLIZATION; HYDROQUINONES; MICROWAVES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; STEREOISOMERISM; THERMODYNAMICS; TRANSCRIPTION FACTOR AP-1;

EID: 80055065626     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo201658y     Document Type: Article

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