Total synthesis of the ubiquitin-activating enzyme inhibitor (+)-panepophenanthrin

Angewandte Chemie - International Edition

Volumn 42, Issue 33, 2003, Pages 3913-3917

  Lei, Xiaoguang ^a   Johnson, Richard P ^b   Porco Jr , John A ^a  

^a USA   (United States)

^b University of New Hampshire   (United States)

Author keywords

Cycloaddition; Epoxyquinoids; Natural products; Total synthesis

Indexed keywords

BIOSYNTHESIS; DIMERIZATION;

EPOXYQUINOLS;

ENZYMES;

ENZYME INHIBITOR; EPOXIDE; EPOXYQUINOID; NATURAL PRODUCT; PANEPOPHENANTHRIN; PHENANTHRENE DERIVATIVE; PROTEASOME; UBIQUITIN; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; CHEMISTRY; CYCLOADDITION; DIELS ALDER REACTION; DIMERIZATION; ENANTIOSELECTIVITY; ENZYME ACTIVITY; ENZYME INHIBITION; EPOXIDATION; NONHUMAN; STEREOCHEMISTRY; STEREOISOMERISM; SYNTHESIS; UPREGULATION;

ENZYME INHIBITORS; EPOXY COMPOUNDS; PHENANTHRENES; STEREOISOMERISM; UBIQUITIN-ACTIVATING ENZYMES; UP-REGULATION;

EID: 0041317053     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200351862     Document Type: Article

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