-
1
-
-
2942726140
-
Statins for stroke prevention: Disappointment and hope
-
109(suppl III):III-44-III-49
-
Amarenco P, Tonkin AM. Statins for stroke prevention: disappointment and hope. Circulation. 2004;109(suppl III):III-44-III-49.
-
(2004)
Circulation
-
-
Amarenco, P.1
Tonkin, A.M.2
-
3
-
-
0032757216
-
Is cholesterol a risk factor for stroke?
-
Landau WM. Is cholesterol a risk factor for stroke? no. Arch Neurol. 1999;56:1521-1524.
-
(1999)
Arch Neurol
, vol.56
, pp. 1521-1524
-
-
Landau, W.M.1
-
4
-
-
0000240129
-
Vascular disease of the brain - epidemiologic aspects: The Framingham Study
-
Kannel WB, Dawber TR, Cohen ME, McNamara PM. Vascular disease of the brain - epidemiologic aspects: the Framingham Study. Am J Public Health. 1965;55:1355-1366.
-
(1965)
Am J Public Health
, vol.55
, pp. 1355-1366
-
-
Kannel, W.B.1
Dawber, T.R.2
Cohen, M.E.3
McNamara, P.M.4
-
5
-
-
0018891035
-
Factors related to stroke incidence in Hawaiian Japanese men: The Honolulu Heart Study
-
Kagan A, Popper JS, Rhoads GG. Factors related to stroke incidence in Hawaiian Japanese men: the Honolulu Heart Study. Stroke. 1980;11:14-21.
-
(1980)
Stroke
, vol.11
, pp. 14-21
-
-
Kagan, A.1
Popper, J.S.2
Rhoads, G.G.3
-
6
-
-
0007402474
-
Randomized trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S)
-
Scandinavian Simvastatin Survival Study Group
-
Scandinavian Simvastatin Survival Study Group. Randomized trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet. 1995;345:1274-1275.
-
(1995)
Lancet
, vol.345
, pp. 1274-1275
-
-
-
7
-
-
0342981862
-
The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels
-
for the Cholesterol and Recurrent Events Trial Investigators
-
Sacks FM, Pfeffer MA, Moye LA, Rouleau JL, Rutherford JD, Cole TG, Brown L, Warnica JW, Arnold JMO, Wun CC, Davis BR, Braunwald E, for the Cholesterol and Recurrent Events Trial Investigators. The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. N Engl J Med. 1996;335:1001-1009.
-
(1996)
N Engl J Med
, vol.335
, pp. 1001-1009
-
-
Sacks, F.M.1
Pfeffer, M.A.2
Moye, L.A.3
Rouleau, J.L.4
Rutherford, J.D.5
Cole, T.G.6
Brown, L.7
Warnica, J.W.8
Arnold, J.M.O.9
Wun, C.C.10
Davis, B.R.11
Braunwald, E.12
-
8
-
-
0032926503
-
Reduction of stroke incidence after myocardial infarction with pravastatin: The Cholesterol And Recurrent Events (CARE) study
-
for the CARE Investigators
-
Plehn JF, Davis BR, Sacks FM, Rouleau JL, Pfeffer MA, Bernstein C, Cuddy E, Moyé LA, Piller LB, Rutherford J, Simpson LM, Braunwald E, for the CARE Investigators. Reduction of stroke incidence after myocardial infarction with pravastatin: the Cholesterol And Recurrent Events (CARE) study. Circulation. 1999;99:216-223.
-
(1999)
Circulation
, vol.99
, pp. 216-223
-
-
Plehn, J.F.1
Davis, B.R.2
Sacks, F.M.3
Rouleau, J.L.4
Pfeffer, M.A.5
Bernstein, C.6
Cuddy, E.7
Moyé, L.A.8
Piller, L.B.9
Rutherford, J.10
Simpson, L.M.11
Braunwald, E.12
-
9
-
-
0032487931
-
Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels
-
The Long-term Intervention with Pravastatin in Ischemic Disease (LIPID) Study Group
-
The Long-term Intervention with Pravastatin in Ischemic Disease (LIPID) Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med. 1998;339:1349-1357.
-
(1998)
N Engl J Med
, vol.339
, pp. 1349-1357
-
-
-
10
-
-
0037132607
-
Major outcomes in moderately hypercholesterolemic, hypertensive patients randomized to pravastatin vs usual care: The Antihypertensive Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT-LLT)
-
The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group
-
The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group. Major outcomes in moderately hypercholesterolemic, hypertensive patients randomized to pravastatin vs usual care: the Antihypertensive Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT-LLT). JAMA. 2002;288:2998-3007.
-
(2002)
JAMA
, vol.288
, pp. 2998-3007
-
-
-
11
-
-
0037164314
-
on behalf of the PROSPER group. Pravastatin in elderly individuals at risk of vascular disease (PROSPER): A randomized controlled trial
-
Shepherd J, Blauw GJ, Murphy MB, Bollen ELEM, Buckley BM, Cobbe SM, Ford I, Gaw A, Hyland M, Jukema JW, Kamper AM, Macfarlane PW, Meinders AE, Norrie J, Packard CJ, Perry IJ, Stott DJ, Sweeney BJ, Twomey C, Westendorp RGJ, on behalf of the PROSPER group. Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomized controlled trial. Lancet. 2002;360:1623-1630.
-
(2002)
Lancet
, vol.360
, pp. 1623-1630
-
-
Shepherd, J.1
Blauw, G.J.2
Murphy, M.B.3
Bollen, E.L.E.M.4
Buckley, B.M.5
Cobbe, S.M.6
Ford, I.7
Gaw, A.8
Hyland, M.9
Jukema, J.W.10
Kamper, A.M.11
Macfarlane, P.W.12
Meinders, A.E.13
Norrie, J.14
Packard, C.J.15
Perry, I.J.16
Stott, D.J.17
Sweeney, B.J.18
Twomey, C.19
Westendorp, R.G.J.20
more..
-
12
-
-
0032169240
-
Inflammation, pravastatin, and the risk of coronary events after myocardial infarction in patients with average cholesterol levels
-
for the Cholesterol and Recurrent Events (CARE) Investigators
-
Ridker PM, Rifai N, Pfeffer MA, Sacks FM, Moye LA, Goldman S, Flaker GC, Braunwald E, for the Cholesterol and Recurrent Events (CARE) Investigators. Inflammation, pravastatin, and the risk of coronary events after myocardial infarction in patients with average cholesterol levels. Circulation. 1998;98:839-844.
-
(1998)
Circulation
, vol.98
, pp. 839-844
-
-
Ridker, P.M.1
Rifai, N.2
Pfeffer, M.A.3
Sacks, F.M.4
Moye, L.A.5
Goldman, S.6
Flaker, G.C.7
Braunwald, E.8
-
13
-
-
0029885126
-
Endothelial dysfunction in atherosclerosis
-
Busse R, Fleming I. Endothelial dysfunction in atherosclerosis. J Vasc Res. 1996;33:181-194.
-
(1996)
J Vasc Res
, vol.33
, pp. 181-194
-
-
Busse, R.1
Fleming, I.2
-
14
-
-
0035172979
-
Hypercholesterolemia impairs endothelium-dependent relaxations in common carotid arteries of apolipoprotein E-deficient mice
-
d'Uscio LV, Smith LA, Katusic ZS. Hypercholesterolemia impairs endothelium-dependent relaxations in common carotid arteries of apolipoprotein E-deficient mice. Stroke. 2001;32:2658-2664.
-
(2001)
Stroke
, vol.32
, pp. 2658-2664
-
-
d'Uscio, L.V.1
Smith, L.A.2
Katusic, Z.S.3
-
15
-
-
0035718119
-
Mechanism of endothelial dysfunction in apolipoprotein E-deficient mice
-
d'Uscio LV, Baker TA, Mantilla CB, Smith L, Weiler D, Sieck GC, Katusic ZS. Mechanism of endothelial dysfunction in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol. 2001;21:1017-1022.
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 1017-1022
-
-
d'Uscio, L.V.1
Baker, T.A.2
Mantilla, C.B.3
Smith, L.4
Weiler, D.5
Sieck, G.C.6
Katusic, Z.S.7
-
16
-
-
0025906819
-
-
Rossitch E Jr, Alexander E 3rd, Black PM, Cooke JP. L-Arginine normalizes endothelial function in cerebral vessels from hypercholesterolemic rabbits. J Clin Invest. 1991;87:1295-1299.
-
Rossitch E Jr, Alexander E 3rd, Black PM, Cooke JP. L-Arginine normalizes endothelial function in cerebral vessels from hypercholesterolemic rabbits. J Clin Invest. 1991;87:1295-1299.
-
-
-
-
17
-
-
0042810670
-
Vascular NAD(P)H oxidases: Specific features, expression, and regulation
-
Lassegue B, Clempus RE. Vascular NAD(P)H oxidases: specific features, expression, and regulation. Am J Physiol Reg Integr Comp Physiol. 2003;285:R277-R292.
-
(2003)
Am J Physiol Reg Integr Comp Physiol
, vol.285
-
-
Lassegue, B.1
Clempus, R.E.2
-
18
-
-
0036081660
-
Effects of NADH and NADPH on superoxide levels and cerebral vascular tone
-
Didion SP, Faraci FM. Effects of NADH and NADPH on superoxide levels and cerebral vascular tone. Am J Physiol. 2002;282:H688-H695.
-
(2002)
Am J Physiol
, vol.282
-
-
Didion, S.P.1
Faraci, F.M.2
-
19
-
-
0842289183
-
Increased NADPH-oxidase activity and Nox4 expression during chronic hypertension is associated with enhanced cerebral vasodilatation to NADPH in vivo
-
Paravicini TM, Chrissobolis S, Drummond GR, Sobey CG. Increased NADPH-oxidase activity and Nox4 expression during chronic hypertension is associated with enhanced cerebral vasodilatation to NADPH in vivo. Stroke. 2004;35:584-589.
-
(2004)
Stroke
, vol.35
, pp. 584-589
-
-
Paravicini, T.M.1
Chrissobolis, S.2
Drummond, G.R.3
Sobey, C.G.4
-
20
-
-
0031440915
-
Atherosclerosis, vascular remodeling, and impairment of endothelium-dependent relaxation in genetically altered hyperlipidemic mice
-
Bonthu S, Heistad DD, Chappell DA, Lamping KG, Faraci FM. Atherosclerosis, vascular remodeling, and impairment of endothelium-dependent relaxation in genetically altered hyperlipidemic mice. Arteriolscler Thromb Vasc Biol. 1997;17:2333-2340.
-
(1997)
Arteriolscler Thromb Vasc Biol
, vol.17
, pp. 2333-2340
-
-
Bonthu, S.1
Heistad, D.D.2
Chappell, D.A.3
Lamping, K.G.4
Faraci, F.M.5
-
21
-
-
0031456565
-
17β-Estradiol prevents fatty streak formation in apolipoprotein E-deficient mice
-
Elhage R, Arnal JF, Pieraggi MT, Duverger N, Fiévet C, Faye JC, Bayard F. 17β-Estradiol prevents fatty streak formation in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol. 1997;17:2679-2684.
-
(1997)
Arterioscler Thromb Vasc Biol
, vol.17
, pp. 2679-2684
-
-
Elhage, R.1
Arnal, J.F.2
Pieraggi, M.T.3
Duverger, N.4
Fiévet, C.5
Faye, J.C.6
Bayard, F.7
-
22
-
-
12844260060
-
Impaired endothelium-dependent responses and enhanced influence of Rho-kinase in cerebral arterioles in type II diabetes
-
Didion SP, Lynch CM, Baumbach GL, Faraci FM. Impaired endothelium-dependent responses and enhanced influence of Rho-kinase in cerebral arterioles in type II diabetes. Stroke. 2005;36:342-347.
-
(2005)
Stroke
, vol.36
, pp. 342-347
-
-
Didion, S.P.1
Lynch, C.M.2
Baumbach, G.L.3
Faraci, F.M.4
-
23
-
-
0030971174
-
Effects of a novel inhibitor of guanylyl cyclase on dilator responses of mouse cerebral arterioles
-
Sobey CG, Faraci FM. Effects of a novel inhibitor of guanylyl cyclase on dilator responses of mouse cerebral arterioles. Stroke. 1997;28:837-842.
-
(1997)
Stroke
, vol.28
, pp. 837-842
-
-
Sobey, C.G.1
Faraci, F.M.2
-
24
-
-
0034129619
-
Role of endogenous nitric oxide in progression of atherosclerosis in apolipoprotein E-deficient mice
-
Kauser K, da Cunha V, Fitch R, Mallari C, Rubanyi GM. Role of endogenous nitric oxide in progression of atherosclerosis in apolipoprotein E-deficient mice. Am J Physiol. 2000;278:H1679-H1685.
-
(2000)
Am J Physiol
, vol.278
-
-
Kauser, K.1
da Cunha, V.2
Fitch, R.3
Mallari, C.4
Rubanyi, G.M.5
-
25
-
-
0031018510
-
Tetrahydrobiopterin restores endothelial function in hypercholesterolemia
-
Stroes E, Kastelein J, Cosentino F, Erkelens W, Wever R, Koomans H, Lüscher TF, Rabelink T. Tetrahydrobiopterin restores endothelial function in hypercholesterolemia. J Clin Invest. 1997;99:41-46.
-
(1997)
J Clin Invest
, vol.99
, pp. 41-46
-
-
Stroes, E.1
Kastelein, J.2
Cosentino, F.3
Erkelens, W.4
Wever, R.5
Koomans, H.6
Lüscher, T.F.7
Rabelink, T.8
-
26
-
-
0032580971
-
Reduced endothelial nitric oxide synthase expression and production in human atherosclerosis
-
Oemar BS, Tschudi MR, Godoy N, Brovkovich V, Malinski T, Lüscher TF. Reduced endothelial nitric oxide synthase expression and production in human atherosclerosis. Circulation. 1998;97:2494-2498.
-
(1998)
Circulation
, vol.97
, pp. 2494-2498
-
-
Oemar, B.S.1
Tschudi, M.R.2
Godoy, N.3
Brovkovich, V.4
Malinski, T.5
Lüscher, T.F.6
-
27
-
-
0028969847
-
Nitric oxide activity in the human coronary circulation: Impact of risk factors for coronary atherosclerosis
-
Quyumi AA, Dakak N, Andrews NP, Husain S, Arora S, Gilligan DM, Panza JA, Cannon RO III. Nitric oxide activity in the human coronary circulation: impact of risk factors for coronary atherosclerosis. J Clin Invest. 1995;95:1747-1755.
-
(1995)
J Clin Invest
, vol.95
, pp. 1747-1755
-
-
Quyumi, A.A.1
Dakak, N.2
Andrews, N.P.3
Husain, S.4
Arora, S.5
Gilligan, D.M.6
Panza, J.A.7
Cannon III, R.O.8
-
28
-
-
2542508741
-
Plasma concentration of asymmetric dimethylarginine, an endogenous inhibitor of nitric oxide synthase, is elevated in monkeys with hyperhomocyst(e)inemia or hypercholesterolemia
-
Böger RH, Bode-Böger SM, Sydow K, Heistad DD, Lentz SR. Plasma concentration of asymmetric dimethylarginine, an endogenous inhibitor of nitric oxide synthase, is elevated in monkeys with hyperhomocyst(e)inemia or hypercholesterolemia. Arterioscler Thromb Vasc Biol. 2000;20:1557-1564.
-
(2000)
Arterioscler Thromb Vasc Biol
, vol.20
, pp. 1557-1564
-
-
Böger, R.H.1
Bode-Böger, S.M.2
Sydow, K.3
Heistad, D.D.4
Lentz, S.R.5
-
29
-
-
0027242030
-
Hypercholesterolemia increases endothelial superoxide anion production
-
Ohara Y, Peterson TE, Harrison DG. Hypercholesterolemia increases endothelial superoxide anion production. J Clin Invest. 1993;91:2546-2551.
-
(1993)
J Clin Invest
, vol.91
, pp. 2546-2551
-
-
Ohara, Y.1
Peterson, T.E.2
Harrison, D.G.3
-
30
-
-
0035896249
-
NAD(P)H oxidase-derived superoxide mediates hypercholesterolemia-induced leukocyte-endothelial cell adhesion
-
Stokes KY, Clanton EC, Russel JM, Ross CR, Granger DN. NAD(P)H oxidase-derived superoxide mediates hypercholesterolemia-induced leukocyte-endothelial cell adhesion. Circ Res. 2001;88:499-505.
-
(2001)
Circ Res
, vol.88
, pp. 499-505
-
-
Stokes, K.Y.1
Clanton, E.C.2
Russel, J.M.3
Ross, C.R.4
Granger, D.N.5
-
31
-
-
0033586639
-
Increased NADH-oxidase-mediated superoxide production in the early stages of atherosclerosis: Evidence for involvement of the renin-angiotensin system
-
Warnholtz A, Nickenig G, Schulz E, Macharzina R, Bräsen JH, Skatchkov M, Heitzer T, Stasch JP, Griendling KK, Harrison DG, Böhm M, Meinertz T, Münzel T. Increased NADH-oxidase-mediated superoxide production in the early stages of atherosclerosis: evidence for involvement of the renin-angiotensin system. Circulation. 1999;99:2027-2033.
-
(1999)
Circulation
, vol.99
, pp. 2027-2033
-
-
Warnholtz, A.1
Nickenig, G.2
Schulz, E.3
Macharzina, R.4
Bräsen, J.H.5
Skatchkov, M.6
Heitzer, T.7
Stasch, J.P.8
Griendling, K.K.9
Harrison, D.G.10
Böhm, M.11
Meinertz, T.12
Münzel, T.13
-
32
-
-
0029133481
-
Native low density lipoprotein increases endothelial cell nitric oxide synthase generation of superoxide anion
-
Pritcherd KA Jr, Groszek L, Smalley DM, Sessa WC, Wu M, Villalon P, Wolin MS, Stemerman MB. Native low density lipoprotein increases endothelial cell nitric oxide synthase generation of superoxide anion. Circ Res. 1995;77:510-518.
-
(1995)
Circ Res
, vol.77
, pp. 510-518
-
-
Pritcherd Jr, K.A.1
Groszek, L.2
Smalley, D.M.3
Sessa, W.C.4
Wu, M.5
Villalon, P.6
Wolin, M.S.7
Stemerman, M.B.8
-
33
-
-
0033781454
-
Modulation of protein kinase activity and gene expression by reactive oxygen species and their role in vascular physiology and pathophysiology
-
Griendling KK, Sorescu D, Lassegue B, Ushio-Fukai M. Modulation of protein kinase activity and gene expression by reactive oxygen species and their role in vascular physiology and pathophysiology. Arterioscler Thromb Vasc Biol. 2000;20:2175-2183.
-
(2000)
Arterioscler Thromb Vasc Biol
, vol.20
, pp. 2175-2183
-
-
Griendling, K.K.1
Sorescu, D.2
Lassegue, B.3
Ushio-Fukai, M.4
-
34
-
-
0345599152
-
Cerebral vascular effects of reactive oxygen species: Recent evidence for a role of NADPH-oxidase
-
Paravicini TM, Sobey CG. Cerebral vascular effects of reactive oxygen species: recent evidence for a role of NADPH-oxidase. Clin Exp Pharmacol Physiol. 2003;30:855-859.
-
(2003)
Clin Exp Pharmacol Physiol
, vol.30
, pp. 855-859
-
-
Paravicini, T.M.1
Sobey, C.G.2
-
35
-
-
8844227341
-
Angiotensin II impairs neurovascular coupling in neocortex through NADPH oxidase-derived radicals
-
Kazama K, Anrather J, Zhou P, Girouard H, Frys K, Milner TA, Iadecola C. Angiotensin II impairs neurovascular coupling in neocortex through NADPH oxidase-derived radicals. Circ Res. 2004;95:1019-1026.
-
(2004)
Circ Res
, vol.95
, pp. 1019-1026
-
-
Kazama, K.1
Anrather, J.2
Zhou, P.3
Girouard, H.4
Frys, K.5
Milner, T.A.6
Iadecola, C.7
-
36
-
-
5344253239
-
Exogenous NADPH increases cerebral blood flow through NADPH oxidase-dependent and -independent mechanisms
-
Park L, Anrather J, Zhou P, Frys K, Wang G, Iadecola C. Exogenous NADPH increases cerebral blood flow through NADPH oxidase-dependent and -independent mechanisms. Arterioscler Thromb Vasc Biol. 2004;24:1860-1865.
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 1860-1865
-
-
Park, L.1
Anrather, J.2
Zhou, P.3
Frys, K.4
Wang, G.5
Iadecola, C.6
-
38
-
-
0032523806
-
Vascular expression of extracellular superoxide dismutase in atherosclerosis
-
Fukai T, Galis ZS, Meng XP, Parthasarathy S, Harrison DG. Vascular expression of extracellular superoxide dismutase in atherosclerosis. J Clin Invest. 1998;101:2101-2111.
-
(1998)
J Clin Invest
, vol.101
, pp. 2101-2111
-
-
Fukai, T.1
Galis, Z.S.2
Meng, X.P.3
Parthasarathy, S.4
Harrison, D.G.5
-
39
-
-
0033646551
-
Decreased sensitivity to nitric oxide in the aorta of severely hypercholesterolemic apolipoprotein E-deficient mice
-
Yaghoubi M, Oliver-Krasinski J, Cayatte AJ, Cohen RA. Decreased sensitivity to nitric oxide in the aorta of severely hypercholesterolemic apolipoprotein E-deficient mice. J Cardiovasc Pharmacol. 2000;36:751-757.
-
(2000)
J Cardiovasc Pharmacol
, vol.36
, pp. 751-757
-
-
Yaghoubi, M.1
Oliver-Krasinski, J.2
Cayatte, A.J.3
Cohen, R.A.4
-
40
-
-
0034745246
-
Mechanisms that produce nitric oxide-mediated relaxation of cerebral arteries during atherosclerosis
-
Didion SP, Heistad DD, Faraci FM. Mechanisms that produce nitric oxide-mediated relaxation of cerebral arteries during atherosclerosis. Stroke. 2001;32:761-766.
-
(2001)
Stroke
, vol.32
, pp. 761-766
-
-
Didion, S.P.1
Heistad, D.D.2
Faraci, F.M.3
|