Enhanced production of human recombinant proteins from CHO cells grown to high densities in macroporous microcarriers

Molecular Biotechnology

Volumn 49, Issue 3, 2011, Pages 263-276

  Tharmalingam, T ^a   Sunley, K ^a   Spearman, M ^a   Butler, M ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Beta interferon; CHO; Cytopore; Microcarrier; Tissue plasminogen activator

Indexed keywords

BETA-INTERFERON; CHO; CYTOPORE; MICROCARRIERS; TISSUE PLASMINOGEN ACTIVATOR;

BIOSYNTHESIS; CELL GROWTH; CELLS; PRODUCTIVITY; PROTEINS; TISSUE;

CELL CULTURE;

ALTEPLASE; RECOMBINANT BETA INTERFERON;

ANIMAL CELL; ARTICLE; CELL DENSITY; CELL GROWTH; CHO CELL; CONTROLLED STUDY; FEMALE; IMMUNOASSAY; MICROCARRIER CULTURE; NONHUMAN; POROSITY; PROTEIN SECRETION; PROTEIN SYNTHESIS; SUSPENSION CELL CULTURE;

ANIMALS; BIOTECHNOLOGY; CELL COUNT; CELL PROLIFERATION; CHO CELLS; CRICETINAE; CRICETULUS; GENTIAN VIOLET; GLUCOSE; HUMANS; INTERFERON-BETA; LACTIC ACID; MICROSCOPY, CONFOCAL; MICROSPHERES; POROSITY; RECOMBINANT PROTEINS; REPRODUCIBILITY OF RESULTS; TISSUE PLASMINOGEN ACTIVATOR;

CRICETULUS GRISEUS;

EID: 80054975034     PISSN: 10736085     EISSN: 15590305     Source Type: Journal    
DOI: 10.1007/s12033-011-9401-y     Document Type: Article

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