Bioactivities of crude caffeine: Antioxidant activity, cyclooxygenase-2 inhibition, and enhanced glucose uptake

Food Chemistry

Volumn 131, Issue 2, 2012, Pages 564-568

  Chu, Yi Fang ^a   Chen, Yumin ^a   Brown, Peter H ^a   Lyle, Barbara J ^a   Black, Richard M ^a   Cheng, Irene H ^b   Ou, Boxin ^c   Prior, Ronald L ^c  

^a Kraft Foods Global Inc   (United States)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c Brunswick Laboratories   (United States)

Author keywords

Anti hyperglycaemic; Anti inflammatory; Antioxidant; Blood glucose; Coffee; Crude caffeine; Oxidative stress

Indexed keywords

ANTI-HYPERGLYCAEMIC; ANTI-INFLAMMATORIES; ANTIOXIDANT; BLOOD GLUCOSE; CRUDE CAFFEINE;

GLUCOSE;

COFFEE;

ACETYLSALICYLIC ACID; ANTIOXIDANT; CAFFEINE; CRUDE CAFFEINE; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; UNCLASSIFIED DRUG;

ADIPOCYTE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DETERMINATION; DRUG POTENCY; DRUG SYNTHESIS; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; HYDROPHILICITY; IC 50; LIPOPHILICITY; MUSCLE CELL; SKELETAL MUSCLE;

EID: 80054948732     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2011.09.024     Document Type: Article

References (37)

1. J.M.A. Araújo, and D. Sandi Extraction of coffee diterpenes and coffee oil using supercritical carbon dioxide Food Chemistry 101 3 2007 1087 1094
2. H. Chen Cellular inflammatory responses: Novel insights for obesity and insulin resistance Pharmacological Research 53 6 2006 469 477 (Pubitemid 43767552)
3. Y.-F. Chu, Y. Chen, R.M. Black, P.H. Brown, B.J. Lyle, and R.H. Liu Type 2 diabetes-related bioactivities of coffee: Assessment of antioxidant activity, NF-κB inhibition, and stimulation of glucose uptake Food Chemistry 124 3 2011 914 920
4. Y.F. Chu, P.H. Brown, B.J. Lyle, Y. Chen, R.M. Black, and C.E. Williams Roasted coffees high in lipophilic antioxidants and chlorogenic acid lactones are more neuroprotective than green coffee Journal of Agricultural and Food Chemistry 57 2009 9801 9808
5. N. D'Amelio, L. Fontanive, F. Uggeri, F. Suggi-Liverani, and L. Navarini NMR Reinvestigation of the caffeine-chlorogenate complex in aqueous solution and in coffee brews Food Biophysics 4 4 2009 321 330
6. M. Daglia, A. Papetti, C. Gregotti, F. Berte, and G. Gazzani In vitro antioxidant and ex vivo protective activities of green and roasted coffee Journal of Agricultural and Food Chemistry 48 5 2000 1449 1454 (Pubitemid 30331471)
7. A.B.A. De Azevedo, T.G. Kieckbush, A.K. Tashima, R.S. Mohamed, P. Mazzafera, and S.A.B.V.d. Melo Extraction of green coffee oil using supercritical carbon dioxide The Journal of Supercritical Fluids 44 2 2008 186 192
8. 2 extraction and purification of compounds with antioxidant activity Journal of Agricultural and Food Chemistry 54 7 2006 2441 2469
9. A. Farah, T. de Paulis, L.C. Trugo, and P.R. Martin Effect of roasting on the formation of chlorogenic acid lactones in coffee Journal of Agricultural and Food Chemistry 53 5 2005 1505 1513 (Pubitemid 40322144)
10. B.L. Fiebich, K. Lieb, M. uuml, ll, B. Aicher, J. van Ryn, and M. Pairet Effects of caffeine and paracetamol alone or in combination with acetylsalicylic acid on prostaglandin E2 synthesis in rat microglial cells Neuropharmacology 39 11 2000 2205 2213 (Pubitemid 30645644)
11. J.A. Gomez-Ruiz, D.S. Leake, and J.M. Ames In vitro antioxidant activity of coffee compounds and their metabolites Journal of Agricultural and Food Chemistry 55 17 2007 6962 6969 (Pubitemid 47338933)
12. T.E. Graham, J.W. Helge, D.A. MacLean, B. Kiens, and E.A. Richter Caffeine ingestion does not alter carbohydrate or fat metabolism in human skeletal muscle during exercise The Journal of Physiology 529 3 2000 837 847 (Pubitemid 32051082)
13. J. Helmersson, B. Vessby, A. Larsson, and S. Basu Association of type 2 diabetes with cyclooxygenase-mediated inflammation and oxidative stress in an elderly population Circulation 109 14 2004 1729 1734 (Pubitemid 38500674)
14. D. Huang, B. Ou, M. Hampsch-Woodill, J.A. Flanagan, and E.K. Deemer Development and validation of oxygen radical absorbance capacity assay for lipophilic antioxidants using randomly methylated beta-cyclodextrin as the solubility enhancer Journal of Agricultural and Food Chemistry 50 7 2002 1815 1821 (Pubitemid 34259972)
15. D. Huang, B. Ou, and R.L. Prior The chemistry behind antioxidant capacity assays Journal of Agricultural and Food Chemistry 53 6 2005 1841 1856 (Pubitemid 40403051)
16. K. Kempf, C. Herder, I. Erlund, H. Kolb, S. Martin, and M. Carstensen Effects of coffee consumption on subclinical inflammation and other risk factors for type 2 diabetes: A clinical trial American Journal of Clinical Nutrition 91 4 2010 950 957
17. K. Kempf, W. Rathmann, and C. Herder Impaired glucose regulation and type 2 diabetes in children and adolescents Diabetes - Metabolism Research and Reviews 24 6 2008 427 437
18. C. Lee Antioxidant ability of caffeine and its metabolites based on the study of oxygen radical absorbing capacity and inhibition of LDL peroxidation Clinica Chimica Acta 295 1-2 2000 141 154 (Pubitemid 30184805)
19. J.-C. Lee, J.K. Kundu, D.-M. Hwang, H.-K. Na, and Y.-J. Surh Humulone inhibits phorbol ester-induced COX-2 expression in mouse skin by blocking activation of NF-kB and AP-1: IkB kinase and c-Jun-N-terminal kinase as respective potential upstream targets Carcinogenesis 28 7 2007 1491 1498 (Pubitemid 47243539)
20. S. Lee, R. Hudson, K. Kilpatrick, T.E. Graham, and R. Ross Caffeine ingestion is associated with reductions in glucose uptake independent of obesity and type 2 diabetes before and after exercise training Diabetes Care 28 3 2005 566 572 (Pubitemid 40315314)
21. Y. Li, J. Kim, J. Li, F. Liu, X. Liu, and K. Himmeldirk Natural anti-diabetic compound 1,2,3,4,6-penta-O-galloyl-d-glucopyranose binds to insulin receptor and activates insulin-mediated glucose transport signaling pathway Biochemical and Biophysical Research Communications 336 2 2005 430 437 (Pubitemid 41267248)
22. R.J.F. Manders, B. Pennings, C.P.G. Beckers, T.I. Aipassa, and L.J.C. van Loon Prevalence of daily hyperglycemia in obese type 2 diabetic men compared with that in lean and obese normoglycemic men: Effect of consumption of a sucrose-containing beverage American Journal of Clinical Nutrition 90 3 2009 511 518
23. N.C. Michael Chlorogenic acids and other cinnamates - nature, occurrence and dietary burden Journal of the Science of Food and Agriculture 79 3 1999 362 372
24. D.P. Moreira, M.C. Monteiro, M. Ribeiro-Alves, C.M. Donangelo, and L.C. Trugo Contribution of chlorogenic acids to the iron-reducing activity of coffee beverages Journal of Agricultural and Food Chemistry 53 5 2005 1399 1402 (Pubitemid 40326269)
25. V.S. Muthusamy, S. Anand, K.N. Sangeetha, S. Sujatha, B. Arun, and B.S. Lakshmi Tannins present in Cichorium intybus enhance glucose uptake and inhibit adipogenesis in 3T3-L1 adipocytes through PTP1B inhibition Chemico-Biological Interactions 174 1 2008 69 78
26. H. Nakabayashi, T. Hashimoto, H. Ashida, S. Nishiumi, and K. Kanazawa Inhibitory effects of caffeine and its metabolites on intracellular lipid accumulation in murine 3T3-L1 adipocytes BioFactors 34 4 2008 293 302
27. B. Ou, M. Hampsch-Woodill, and R.L. Prior Development and validation of an improved oxygen radical absorbance capacity assay using fluorescein as the fluorescent probe Journal of Agricultural and Food Chemistry 49 10 2001 4619 4626 (Pubitemid 32988695)
28. A.G. Schauss, X. Wu, R.L. Prior, B. Ou, D. Huang, and J. Owens Antioxidant capacity and other bioactivities of the freeze-dried amazonian palm berry, Euterpe oleraceae Mart. (Acai) Journal of Agricultural and Food Chemistry 54 22 2006 8604 8610 (Pubitemid 44747672)
29. X. Shi, N.S. Dalal, and A.C. Jain Antioxidant behaviour of caffeine: Efficient scavenging of hydroxyl radicals Food and Chemical Toxicology 29 1 1991 1 6
30. S.E. Shoelson, J. Lee, and A.B. Goldfine Inflammation and insulin resistance Journal of Clinical Investigation 116 7 2006 1793 1801 (Pubitemid 44033299)
31. V.L. Singleton, and J.A. Rossi Jr. Colourimetry of total phenolics with phosphomolybdic-phosphotungstic acid reagents American Journal of Enology and Viticulture 16 3 1965 144 158
32. A. Svilaas, A.K. Sakhi, L.F. Andersen, T. Svilaas, E.C. Strom, and D.R. Jacobs Intakes of antioxidants in coffee, wine, and vegetables are correlated with plasma carotenoids in humans Journal of Nutrition 134 3 2004 562 567 (Pubitemid 38298496)
33. F.S.L. Thong, W. Derave, B. Kiens, T.E. Graham, B. UrsÃ, and F.P. Wojtaszewski Jr. Caffeine-induced impairment of insulin action but not insulin signaling in human skeletal muscle is reduced by exercise Diabetes 51 3 2002 583 590 (Pubitemid 34760163)
34. J.R. Vane, Y.S. Bakhle, and R.M. Botting Cyclooxygenases 1 and 2 Annual Review of Pharmacology and Toxicology 38 1 1998 97 120 (Pubitemid 28231490)
35. S.S.M. Waldhauser, and T.W. Baumann Compartmentation of caffeine and related purine alkaloids depends exclusively on the physical chemistry of their vacuolar complex formation with chlorogenic acids Phytochemistry 42 4 1996 985 996 (Pubitemid 27068429)
36. K.E. Wellen, and G.S. Hotamisligil Inflammation, stress, and diabetes Journal of Clinical Investigation 115 5 2005 1111 1119 (Pubitemid 40629025)
37. X. Wu, G.R. Beecher, J.M. Holden, D.B. Haytowitz, S.E. Gebhardt, and R.L. Prior Lipophilic and hydrophilic antioxidant capacities of common foods in the United States Journal of Agricultural and Food Chemistry 52 12 2004 4026 4037