The extracts of Fructus Akebiae, a preparation containing 90% of the active ingredient hederagenin: Serotonin, norepinephrine and dopamine reuptake inhibitor

Pharmacology Biochemistry and Behavior

Volumn 100, Issue 3, 2012, Pages 431-439

  Jin, Zeng Liang ^a,c   Gao, Nana ^b   Zhou, Dan ^a   Chi, Mu Gen ^c   Yang, Xue Mei ^a   Xu, Jiang Ping ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b INSTITUTE OF MEDICINAL BIOTECHNOLOGY   (China)

^c BEIJING INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (China)

Author keywords

Antidepressant; Fructus Akebiae; Reuptake inhibitor

Indexed keywords

DESIPRAMINE; DOPAMINE; DOPAMINE TRANSPORTER; FLUOXETINE; FRUCTUS AKEBIAE EXTRACT; HEDERAGENIN; MONOAMINE; NOMIFENSINE; NORADRENALIN; NORADRENALIN TRANSPORTER; SEROTONIN; SEROTONIN TRANSPORTER; TRIPLE REUPTAKE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BRAIN MEMBRANE; CELL STRAIN HEK293; DRUG INHIBITION; DRUG PROTEIN BINDING; FRONTAL CORTEX; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IC 50; LIGAND BINDING; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SYNAPTOSOME;

ANIMALS; BIOGENIC MONOAMINES; BRAIN; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; FRONTAL LOBE; HEK293 CELLS; HUMANS; MALE; NERVE TISSUE PROTEINS; NEURONS; NEUROTRANSMITTER UPTAKE INHIBITORS; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; OLEANOLIC ACID; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; SYNAPTOSOMES; UP-REGULATION;

ANIMALIA; RATTUS;

EID: 80054936049     PISSN: 00913057     EISSN: 18735177     Source Type: Journal    
DOI: 10.1016/j.pbb.2011.10.001     Document Type: Article

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