Statins inhibit iNOS-mediated microbicidal potential of activated monocyte-derived dendritic cells by an IFN-β-dependent mechanism

European Journal of Immunology

Volumn 41, Issue 11, 2011, Pages 3330-3339

  Domínguez, Pilar M ^a   López Bravo, María ^a   Kalinke, Ulrich ^b   Ardavín, Carlos ^a  

^a CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

^b INSTITUTE OF INFECTION IMMUNOLOGY   (Germany)

Author keywords

Inflammatory DCs; INOS; Monocytes; Statins; Type I IFN

Indexed keywords

ALPHA BETA INTERFERON RECEPTOR; BETA INTERFERON; HEME OXYGENASE 1; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERFERON REGULATORY FACTOR 1; MEVINOLIN; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBACTERIAL ACTIVITY; ARTICLE; AUTOCRINE EFFECT; CELL ACTIVATION; CELL DIFFERENTIATION; CELL PROTECTION; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; DRUG EFFECT; ENZYME ACTIVATION; ENZYME INHIBITION; FEMALE; IMMUNOBIOLOGY; IN VIVO STUDY; LISTERIOSIS; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALS; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL SEPARATION; DENDRITIC CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; INTERFERON-BETA; LISTERIOSIS; LOVASTATIN; MICE; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; MONOCYTES; NITRIC OXIDE SYNTHASE TYPE II; POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 80054900348     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201141674     Document Type: Article

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