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Volumn 141, Issue 5, 2011, Pages 1887-1896.e2

Loss of interleukin-10 or transforming growth factor β signaling in the human colon initiates a T-helper 1 response via distinct pathways

Author keywords

Crohn's Disease; Human Tissue Samples; Inflammasome; Inflammation; Mucosa Resident Cells

Indexed keywords

CASPASE INHIBITOR; GAMMA INTERFERON; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 18; RECOMBINANT INTERLEUKIN 18; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; YVAD FMK; ZVAD;

EID: 80054875951     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2011.08.002     Document Type: Article
Times cited : (23)

References (33)
  • 1
    • 42549143615 scopus 로고    scopus 로고
    • Blockade of transforming growth factor beta upregulates T-box transcription factor T-bet, and increases T helper cell type 1 cytokine and matrix metalloproteinase-3 production in the human gut mucosa
    • DOI 10.1136/gut.2007.130922
    • Di Sabatino A, Pickard KM, Rampton D, et al. Blockade of transforming growth factor beta upregulates T-box transcription factor T-bet, and increases T helper cell type 1 cytokine and matrix metalloproteinase-3 production in the human gut mucosa. Gut 2008;57:605-612. (Pubitemid 351579972)
    • (2008) Gut , vol.57 , Issue.5 , pp. 605-612
    • Di, S.A.1    Pickard, K.M.2    Rampton, D.3    Kruidenier, L.4    Rovedatti, L.5    Leakey, N.A.B.6    Corazza, G.R.7    Monteleone, G.8    MacDonald, T.T.9
  • 2
    • 40549113336 scopus 로고    scopus 로고
    • Mucosal IL-10 and TGF-beta play crucial roles in preventing LPS-driven, IFN-gamma-mediated epithelial damage in human colon explants
    • DOI 10.1172/JCI32140
    • Jarry A, Bossard C, Bou-Hanna C, et al. Mucosal IL-10 and TGFbeta play crucial roles in preventing LPS-driven, IFN-gamma-mediated epithelial damage in human colon explants. J Clin Invest 2008;118:1132-1142. (Pubitemid 351364620)
    • (2008) Journal of Clinical Investigation , vol.118 , Issue.3 , pp. 1132-1142
    • Jarry, A.1    Bossard, C.2    Bou-Hanna, C.3    Masson, D.4    Espaze, E.5    Denis, M.G.6    Laboisse, C.L.7
  • 3
    • 33847381116 scopus 로고    scopus 로고
    • The fundamental basis of inflammatory bowel disease
    • DOI 10.1172/JCI30587
    • Strober W, Fuss I, Mannon P. The fundamental basis of inflammatory bowel disease. J Clin Invest 2007;117:514-521. (Pubitemid 46348505)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.3 , pp. 514-521
    • Strober, W.1    Fuss, I.2    Mannon, P.3
  • 5
    • 65549131489 scopus 로고    scopus 로고
    • Defective IL-10 production in severe phenotypes of Crohn's disease
    • Correa I, Veny M, Esteller M, et al. Defective IL-10 production in severe phenotypes of Crohn's disease. J Leukoc Biol 2009;85:896-903.
    • (2009) J Leukoc Biol , vol.85 , pp. 896-903
    • Correa, I.1    Veny, M.2    Esteller, M.3
  • 6
    • 65249115914 scopus 로고    scopus 로고
    • A Crohn's disease-associated NOD2 mutation suppresses transcription of human IL10 by inhibiting activity of the nuclear ribonucleoprotein hnRNP-A1
    • Noguchi E, Homma Y, Kang X, et al. A Crohn's disease-associated NOD2 mutation suppresses transcription of human IL10 by inhibiting activity of the nuclear ribonucleoprotein hnRNP-A1. Nat Immunol 2009;10:471-479.
    • (2009) Nat Immunol , vol.10 , pp. 471-479
    • Noguchi, E.1    Homma, Y.2    Kang, X.3
  • 7
    • 70949087383 scopus 로고    scopus 로고
    • Inflammatory bowel disease and mutations affecting the interleukin-10 receptor
    • Glocker EO, Kotlarz D, Boztug K, et al. Inflammatory bowel disease and mutations affecting the interleukin-10 receptor. N Engl J Med 2009;361:2033-2045.
    • (2009) N Engl J Med , vol.361 , pp. 2033-2045
    • Glocker, E.O.1    Kotlarz, D.2    Boztug, K.3
  • 8
    • 0037313578 scopus 로고    scopus 로고
    • Interleukin-12 and the regulation of innate resistance and adaptive immunity
    • DOI 10.1038/nri1001
    • Trinchieri G. Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat Rev Immunol 2003;3:133-146. (Pubitemid 37328691)
    • (2003) Nature Reviews Immunology , vol.3 , Issue.2 , pp. 133-146
    • Trinchieri, G.1
  • 9
    • 2542457495 scopus 로고    scopus 로고
    • Inflammatory caspases: Linking an intracellular innate immune system to autoinflammatory diseases
    • DOI 10.1016/j.cell.2004.05.004, PII S0092867404004908
    • Martinon F, Tschopp J. Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases. Cell 2004;117:561-574. (Pubitemid 38692523)
    • (2004) Cell , vol.117 , Issue.5 , pp. 561-574
    • Martinon, F.1    Tschopp, J.2
  • 10
  • 11
    • 0030995575 scopus 로고    scopus 로고
    • Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells
    • DOI 10.1016/S0016-5085(97)70128-8
    • Monteleone G, Biancone L, Marasco R, et al. Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells. Gastroenterology 1997;112:1169-1178. (Pubitemid 27157528)
    • (1997) Gastroenterology , vol.112 , Issue.4 , pp. 1169-1178
    • Monteleone, G.1    Biancone, L.2    Marasco, R.3    Morrone, G.4    Marasco, O.5    Luzza, F.6    Pallone, F.7
  • 15
    • 0036842274 scopus 로고    scopus 로고
    • Flow cytometric detection of intracellular IL-12 release: In vitro effect of widely used immunosuppressants
    • DOI 10.1016/S1567-5769(02)00208-4, PII S1567576902002084
    • Tsiavou A, Degiannis D, Hatziagelaki E, et al. Flow cytometric detection of intracellular IL-12 release: in vitro effect of widely used immunosuppressants. Int Immunopharmacol 2002;2:1713-1720. (Pubitemid 35284609)
    • (2002) International Immunopharmacology , vol.2 , Issue.12 , pp. 1713-1720
    • Tsiavou, A.1    Degiannis, D.2    Hatziagelaki, E.3    Koniavitou, K.4    Raptis, S.5
  • 17
    • 0032983336 scopus 로고    scopus 로고
    • Interleukin-18 binding protein: A novel modulator of the Th1 cytokine response
    • DOI 10.1016/S1074-7613(00)80013-8
    • Novick D, Kim SH, Fantuzzi G, et al. Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response. Immunity 1999;10:127-136. (Pubitemid 29077390)
    • (1999) Immunity , vol.10 , Issue.1 , pp. 127-136
    • Novick, D.1    Kim, S.-H.2    Fantuzzi, G.3    Reznikov, L.L.4    Dinarello, C.A.5    Rubinstein, M.6
  • 19
    • 0034924028 scopus 로고    scopus 로고
    • Loss of transforming growth factor beta signalling in the intestine contributes to tissue injury in inflammatory bowel disease
    • DOI 10.1136/gut.49.2.190
    • Hahm KB, Im YH, Parks TW, et al. Loss of transforming growth factor beta signalling in the intestine contributes to tissue injury in inflammatory bowel disease. Gut 2001;49:190-198. (Pubitemid 32675110)
    • (2001) Gut , vol.49 , Issue.2 , pp. 190-198
    • Hahm, K.-B.1    Im, Y.-H.2    Parks, T.W.3    Park, S.-H.4    Markowitz, S.5    Jung, H.-Y.6    Green, J.7    Kim, S.-J.8
  • 21
    • 0031253731 scopus 로고    scopus 로고
    • TGF-beta Production Regulates the Development of the 2,4,6- Trinitrophenol-Conjugated Keyhole Limpet Hemocyanin-Induced Colonic Inflammation in IL-2-Deficient Mice
    • Ludviksson BR, Ehrhardt RO, Strober W. TGF-beta production regulates the development of the 2,4,6-trinitrophenol-conjugated keyhole limpet hemocyanin-induced colonic inflammation in IL-2-deficient mice. J Immunol 1997;159:3622-3628. (Pubitemid 127482122)
    • (1997) Journal of Immunology , vol.159 , Issue.7 , pp. 3622-3628
    • Ludviksson, B.R.1    Ehrhardt, R.O.2    Strober, W.3
  • 22
    • 0037080032 scopus 로고    scopus 로고
    • The interrelated roles of TGF-beta and IL-10 in the regulation of experimental colitis
    • Fuss IJ, Boirivant M, Lacy B, et al. The interrelated roles of TGF-beta and IL-10 in the regulation of experimental colitis. J Immunol 2002;168:900-908. (Pubitemid 34049594)
    • (2002) Journal of Immunology , vol.168 , Issue.2 , pp. 900-908
    • Fuss, I.J.1    Boirivant, M.2    Lacy, B.3    Strober, W.4
  • 23
    • 0034600789 scopus 로고    scopus 로고
    • Treatment of experimental (trinitrobenzene sulfonic acid) colitis by intranasal administration of transforming growth factor (TGF)-beta1 plasmid:TGF-beta1-mediated suppression of T helper cell type 1 response occurs by interleukin (IL)-10 induction and IL-12 receptor beta2 chain downregulation
    • DOI 10.1084/jem.192.1.41
    • Kitani A, Fuss IJ, Nakamura K, et al. Treatment of experimental (Trinitrobenzene sulfonic acid) colitis by intranasal administration of transforming growth factor (TGF)-beta1 plasmid: TGF-beta1- mediated suppression of T helper cell type 1 response occurs by interleukin (IL)-10 induction and IL-12 receptor beta2 chain downregulation. J Exp Med 2000;192:41-52. (Pubitemid 30470805)
    • (2000) Journal of Experimental Medicine , vol.192 , Issue.1 , pp. 41-52
    • Kitani, A.1    Fuss, I.J.2    Nakamura, K.3    Schwartz, O.M.4    Usui, T.5    Strober, W.6
  • 24
    • 3943094621 scopus 로고    scopus 로고
    • Lymphocytes endowed with colon-selective homing and engineered to produce TGF-beta1 prevent the development of dinitrobenzene sulphonic acid colitis
    • DOI 10.1097/00042737-200312000-00002
    • Castagliuolo I, Brun P, Tormen D, et al. Lymphocytes endowed with colon-selective homing and engineered to produce TGF-beta1 prevent the development of dinitrobenzene sulphonic acid colitis. Eur J Gastroenterol Hepatol 2003;15:1257-1265. (Pubitemid 39049667)
    • (2003) European Journal of Gastroenterology and Hepatology , vol.15 , Issue.12 , pp. 1257-1265
    • Castagliuolo, I.1    Brun, P.2    Tormen, D.3    Palu, G.4
  • 25
    • 0028861975 scopus 로고
    • Antibodies to interleukin 12 abrogate established experimental colitis in mice
    • Neurath MF, Fuss I, Kelsall BL, et al. Antibodies to interleukin 12 abrogate established experimental colitis in mice. J Exp Med 1995;182:1281-1290.
    • (1995) J Exp Med , vol.182 , pp. 1281-1290
    • Neurath, M.F.1    Fuss, I.2    Kelsall, B.L.3
  • 26
    • 0032698471 scopus 로고    scopus 로고
    • IL-12-induced IFN-gamma is dependent on caspase-1 processing of the IL-18 precursor
    • Fantuzzi G, Reed DA, Dinarello CA. IL-12-induced IFN-gamma is dependent on caspase-1 processing of the IL-18 precursor. J Clin Invest 1999;104:761-767. (Pubitemid 29536361)
    • (1999) Journal of Clinical Investigation , vol.104 , Issue.6 , pp. 761-767
    • Fantuzzi, G.1    Reed, D.A.2    Dinarello, C.A.3
  • 27
    • 0034668049 scopus 로고    scopus 로고
    • Rapid recruitment of neutrophils containing prestored IL-12 during microbial infection
    • Bliss SK, Butcher BA, Denkers EY. Rapid recruitment of neutrophils containing prestored IL-12 during microbial infection. J Immunol 2000;165:4515-4521.
    • (2000) J Immunol , vol.165 , pp. 4515-4521
    • Bliss, S.K.1    Butcher, B.A.2    Denkers, E.Y.3
  • 28
    • 0034698826 scopus 로고    scopus 로고
    • Preformed membraneassociated stores of interleukin (IL)-12 are a previously unrecognized source of bioactive IL-12 that is mobilized within minutes of contact with an intracellular parasite
    • Quinones M, Ahuja SK, Melby PC, et al. Preformed membraneassociated stores of interleukin (IL)-12 are a previously unrecognized source of bioactive IL-12 that is mobilized within minutes of contact with an intracellular parasite. J Exp Med 2000;192:507-516.
    • (2000) J Exp Med , vol.192 , pp. 507-516
    • Quinones, M.1    Ahuja, S.K.2    Melby, P.C.3
  • 30
    • 0031921472 scopus 로고    scopus 로고
    • Expression of interleukin 1beta and interleukin 1beta converting enzyme by intestinal macrophages in health and inflammatory bowel disease
    • McAlindon ME, Hawkey CJ, Mahida YR. Expression of interleukin 1 beta and interleukin 1 beta converting enzyme by intestinal macrophages in health and inflammatory bowel disease. Gut 1998; 42:214-219. (Pubitemid 28212176)
    • (1998) Gut , vol.42 , Issue.2 , pp. 214-219
    • McAlindon, M.E.1    Hawkey, C.J.2    Mahida, Y.R.3
  • 32
    • 0141886175 scopus 로고    scopus 로고
    • IFN-gamma-independent effects of IL-12 during intestinal nematode infection
    • Helmby H, Grencis RK. IFN-gamma-independent effects of IL-12 during intestinal nematode infection. J Immunol 2003;171:3691-3696. (Pubitemid 37254573)
    • (2003) Journal of Immunology , vol.171 , Issue.7 , pp. 3691-3696
    • Helmby, H.1    Grencis, R.K.2
  • 33
    • 0028670487 scopus 로고
    • Interferon gamma-independent effects of interleukin 12 administered during acute or established infection due to Leishmania major
    • Wang ZE, Zheng, Corry DB, et al. Interferon gamma-independent effects of interleukin 12 administered during acute or established infection due to Leishmania major. Proc Natl Acad Sci U S A 1994;91:12932-12936.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 12932-12936
    • Wang, Z.E.1    Zheng2    Corry, D.B.3


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