Heat shock protein 60 protects skeletal tissue against glucocorticoid-induced bone mass loss by regulating osteoblast survival

Bone

Volumn 49, Issue 5, 2011, Pages 1080-1089

  Wang, Feng Sheng ^a,b   Wu, Re Wen ^a   Ko, Jih Yang ^a   Tai, Ming Hong ^c   Ke, Huei Ching ^a   Yeh, Da Wei ^a   Wu, Shin Long ^a   Chen, Ming Wen ^a  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^b CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^c NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; Bone loss; Glucocorticoid; Heat shock protein 60; Osteoblast

Indexed keywords

ADENOVIRUS VECTOR; ANTISENSE OLIGONUCLEOTIDE; CASPASE 3; COLLAGEN TYPE 1; CYTOCHROME C; DEXAMETHASONE; HEAT SHOCK PROTEIN 60; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN BAX; PROTEIN KINASE B;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BONE DENSITY; BONE FRAGILITY; BONE MASS; BONE STRENGTH; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG INDUCED DISEASE; ENZYME ACTIVATION; MALE; METAPHYSIS; NONHUMAN; OSTEOBLAST; OSTEOLYSIS; PROTECTION; PROTEIN CLEAVAGE; PROTEIN SECRETION; PROTEOMICS; RAT; SIGNAL TRANSDUCTION; TRABECULAR BONE; VIRAL GENE DELIVERY SYSTEM;

ABSORPTIOMETRY, PHOTON; ANIMALS; BONE AND BONES; BONE DENSITY; CHAPERONIN 60; DNA PRIMERS; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; GLUCOCORTICOIDS; MASS SPECTROMETRY; OSTEOBLASTS; OSTEOPOROSIS; PROTEOMICS; RATS; REAL-TIME POLYMERASE CHAIN REACTION; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TOMOGRAPHY, X-RAY COMPUTED;

EID: 80054845543     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2011.08.006     Document Type: Article

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