Bisphosphonates activate nucleotide receptors signaling and induce the expression of Hsp90 in osteoblast-like cell lines

Bone

Volumn 39, Issue 4, 2006, Pages 739-753

  Romanello, Milena ^a   Bivi, Nicoletta ^a   Pines, Alex ^a   Deganuto, Marta ^a   Quadrifoglio, Franco ^a   Moro, Luigi ^b,c   Tell, Gianluca ^a  

^a UNIVERSITY OF UDINE   (Italy)

^b UNIVERSITY OF TRIESTE   (Italy)

^c Center for the Study of Metabolic Bone Diseases   (Italy)

Author keywords

ATP release; Bisphosphonates; Hsp90; Osteoblasts; P2 receptors

Indexed keywords

ADENOSINE TRIPHOSPHATE; BISPHOSPHONIC ACID DERIVATIVE; HEAT SHOCK PROTEIN 90; MITOGEN ACTIVATED PROTEIN KINASE; PURINE P2Y RECEPTOR; PURINE P2Y1 RECEPTOR; PURINE P2Y2 RECEPTOR; RISEDRONIC ACID;

ARTICLE; BONE ATROPHY; BONE GROWTH; CELL CULTURE; CELL PROLIFERATION; CELL STIMULATION; CONTROLLED STUDY; DRUG ACTIVITY; ENZYME ACTIVATION; ENZYME RELEASE; HUMAN; HUMAN CELL; MECHANICAL STRESS; MITOGENESIS; OSTEOBLAST; OSTEOPOROSIS; PROTEIN ANALYSIS; PROTEOMICS; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION;

ADENOSINE TRIPHOSPHATE; ALENDRONATE; APYRASE; BLOTTING, WESTERN; CELL LINE; CELL LINE, TUMOR; CELL SURVIVAL; DIPHOSPHONATES; ETIDRONIC ACID; HSP90 HEAT-SHOCK PROTEINS; HUMANS; MASS SPECTROMETRY; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MODELS, BIOLOGICAL; OSTEOBLASTS; RECEPTORS, PURINERGIC P2; SIGNAL TRANSDUCTION; SURAMIN;

EID: 33748343164     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2006.03.011     Document Type: Article

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