Overexpression of KLF15 transcription factor in adipocytes of mice results in down-regulation of SCD1 protein expression in adipocytes and consequent enhancement of glucose-induced insulin secretion

Journal of Biological Chemistry

Volumn 286, Issue 43, 2011, Pages 37458-37469

  Nagare, Tomoki ^a,b   Sakaue, Hiroshi ^b,c   Matsumoto, Michihiro ^a   Cao, Yongheng ^a   Inagaki, Kenjiro ^a   Sakai, Mashito ^a   Takashima, Yasuhiro ^b   Nakamura, Kyoko ^b   Mori, Toshiyuki ^b   Okada, Yuko ^b   Matsuki, Yasushi ^d   Watanabe, Eijiro ^d   Ikeda, Kazutaka ^e,f,g   Taguchi, Ryo ^f,g,h   Kamimura, Naomi ⁱ   Ohta, Shigeo ⁱ   Hiramatsu, Ryuji ^d   Kasuga, Masato ^a,b  

^a NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^b KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF TOKUSHIMA   (Japan)

^d DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

^e KEIO UNIVERSITY   (Japan)

^f UNIVERSITY OF TOKYO   (Japan)

^g JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^h CHUBU UNIVERSITY   (Japan)

ⁱ NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; MAMMALS; NUTRITION; TRANSCRIPTION;

GLUCOSE TOLERANCE; INSULIN RESISTANCE; INSULIN SECRETION; PANCREATIC BETA CELLS; PATHOLOGICAL CONDITIONS; PROTEIN EXPRESSIONS; STEAROYL-COA DESATURASE; WHITE ADIPOSE TISSUES;

TISSUE;

ACYL COENZYME A DESATURASE 1; KRUPPEL LIKE FACTOR; KRUPPEL LIKE FACTOR 15; UNCLASSIFIED DRUG;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BROWN ADIPOSE TISSUE; CONTROLLED STUDY; DOWN REGULATION; GENE; GENE OVEREXPRESSION; INSULIN RELEASE; INSULIN RESISTANCE; KLF15 GENE; LIPID PEROXIDATION; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; WHITE ADIPOSE TISSUE;

MUS;

EID: 80054797295     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.242651     Document Type: Article

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