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Volumn 47, Issue 11, 2011, Pages 1032-1038

Apicidin, a histone deaceylase inhibitor, induces both apoptosis and autophagy in human oral squamous carcinoma cells

Author keywords

Apicidin; Apoptosis; Autophagy; Cell cycle; HDAC inhibitor; Oral cancer; Oral squamous cell carcinoma

Indexed keywords

APICIDIN; AUTOPHAGY PROTEIN 5; CYCLIN DEPENDENT KINASE INHIBITOR 1; HISTONE H3; HISTONE H4; MEMBRANE PROTEIN; PROTEIN LC3B2; UNCLASSIFIED DRUG;

EID: 80054795576     PISSN: 13688375     EISSN: 18790593     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2011.07.027     Document Type: Article
Times cited : (52)

References (37)
  • 1
    • 30844459038 scopus 로고    scopus 로고
    • Squamous cell carcinoma of the oral cavity, maxillary antrum and lip in a Zimbabwean population: A descriptive study
    • M.M. Chidzonga, and L. Mahomva Squamous cell carcinoma of the oral cavity, maxillary antrum and lip in a Zimbabwean population: a descriptive study Oral Oncol 42 2 2006 184 186
    • (2006) Oral Oncol , vol.42 , Issue.2 , pp. 184-186
    • Chidzonga, M.M.1    Mahomva, L.2
  • 3
    • 34247102349 scopus 로고    scopus 로고
    • Assessment of risk factors for oral squamous cell carcinoma in Chidambaram, southern India: A case-control study
    • DOI 10.1097/01.cej.0000228402.53106.9e, PII 0000846920070600000012
    • R. Subapriya, A. Thangavelu, B. Mathavan, C.R. Ramachandran, and S. Nagini Assessment of risk factors for oral squamous cell carcinoma in Chidambaram, Southern India: a case-control study Eur J Cancer Prev 16 3 2007 251 256 (Pubitemid 46597429)
    • (2007) European Journal of Cancer Prevention , vol.16 , Issue.3 , pp. 251-256
    • Subapriya, R.1    Thangavelu, A.2    Mathavan, B.3    Ramachandran, C.R.4    Nagini, S.5
  • 5
    • 77649185149 scopus 로고    scopus 로고
    • Aspirin induces apoptosis in YD-8 human oral squamous carcinoma cells through activation of caspases, down-regulation of Mcl-1, and inactivation of ERK-1/2 and AKT
    • I.S. Park, J.R. Jo, H. Hong, K.Y. Nam, J.B. Kim, and S.H. Hwang Aspirin induces apoptosis in YD-8 human oral squamous carcinoma cells through activation of caspases, down-regulation of Mcl-1, and inactivation of ERK-1/2 and AKT Toxicol In Vitro 24 3 2010 713 720
    • (2010) Toxicol in Vitro , vol.24 , Issue.3 , pp. 713-720
    • Park, I.S.1    Jo, J.R.2    Hong, H.3    Nam, K.Y.4    Kim, J.B.5    Hwang, S.H.6
  • 7
    • 78149376272 scopus 로고    scopus 로고
    • Anticancer effect of photodynamic therapy with hexenyl ester of 5-aminolevulinic acid in oral squamous cell carcinoma
    • Y.H. Moon, J.H. Park, S.A. Kim, J.B. Lee, S.G. Ahn, and J.H. Yoon Anticancer effect of photodynamic therapy with hexenyl ester of 5-aminolevulinic acid in oral squamous cell carcinoma Head Neck 32 9 2010 1136 1142
    • (2010) Head Neck , vol.32 , Issue.9 , pp. 1136-1142
    • Moon, Y.H.1    Park, J.H.2    Kim, S.A.3    Lee, J.B.4    Ahn, S.G.5    Yoon, J.H.6
  • 8
    • 36048958965 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: Overview and perspectives
    • DOI 10.1158/1541-7786.MCR-07-0324
    • M. Dokmanovic, C. Clarke, and P.A. Marks Histone deacetylase inhibitors: overview and perspectives Mol Cancer Res 5 10 2007 981 989 (Pubitemid 350080267)
    • (2007) Molecular Cancer Research , vol.5 , Issue.10 , pp. 981-989
    • Dokmanovic, M.1    Clarke, C.2    Marks, P.A.3
  • 9
    • 49349098483 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: Mechanisms of cell death and promise in combination cancer therapy
    • J.S. Carew, F.J. Giles, and S.T. Nawrocki Histone deacetylase inhibitors: mechanisms of cell death and promise in combination cancer therapy Cancer Lett 269 1 2008 7 17
    • (2008) Cancer Lett , vol.269 , Issue.1 , pp. 7-17
    • Carew, J.S.1    Giles, F.J.2    Nawrocki, S.T.3
  • 10
    • 39149114438 scopus 로고    scopus 로고
    • HDAC inhibitors: A potential new category of anti-tumor agents
    • L.N. Pan, J. Lu, and B. Huang HDAC inhibitors: a potential new category of anti-tumor agents Cell Mol Immun 4 5 2007 337 343
    • (2007) Cell Mol Immun , vol.4 , Issue.5 , pp. 337-343
    • Pan, L.N.1    Lu, J.2    Huang, B.3
  • 11
    • 25144440127 scopus 로고    scopus 로고
    • Rational development of histone deacetylase inhibitors as anticancer agents: A review
    • DOI 10.1124/mol.105.014167
    • M.R. Acharya, A. Sparreboom, J. Venitz, and W.D. Figg Rational development of histone deacetylase inhibitors as anticancer agents: a review Mol Pharmacol 68 4 2005 917 932 (Pubitemid 41345783)
    • (2005) Molecular Pharmacology , vol.68 , Issue.4 , pp. 917-932
    • Acharya, M.R.1    Sparreboom, A.2    Venitz, J.3    Figg, W.D.4
  • 12
    • 0034837064 scopus 로고    scopus 로고
    • Inhibitors of histone deacetylase as new anticancer agents
    • M. Jung Inhibitors of histone deacetylase as new anticancer agents Curr Med Chem 8 12 2001 1505 1511 (Pubitemid 32894012)
    • (2001) Current Medicinal Chemistry , vol.8 , Issue.12 , pp. 1505-1511
    • Jung, M.1
  • 13
    • 37349061341 scopus 로고    scopus 로고
    • A natural histone deacetylase inhibitor, Psammaplin A, induces cell cycle arrest and apoptosis in human endometrial cancer cells
    • DOI 10.1016/j.ygyno.2007.08.098, PII S0090825807007135
    • M.Y. Ahn, J.H. Jung, Y.J. Na, and H.S. Kim A natural histone deacetylase inhibitor, Psammaplin A, induces cell cycle arrest and apoptosis in human endometrial cancer cells Gynecol Oncol 108 1 2008 27 33 (Pubitemid 350299431)
    • (2008) Gynecologic Oncology , vol.108 , Issue.1 , pp. 27-33
    • Ahn, M.Y.1    Jung, J.H.2    Na, Y.J.3    Kim, H.S.4
  • 14
    • 77950865895 scopus 로고    scopus 로고
    • Potential role of HDAC inhibitors in cancer therapy: Insights into oral squamous cell carcinoma
    • A. Iglesias-Linares, R.M. Yañez-Vico, and M.A. González- Moles Potential role of HDAC inhibitors in cancer therapy: insights into oral squamous cell carcinoma Oral Oncol 46 5 2010 323 329
    • (2010) Oral Oncol , vol.46 , Issue.5 , pp. 323-329
    • Iglesias-Linares, A.1    Yañez-Vico, R.M.2    González-Moles, M.A.3
  • 16
    • 0034192770 scopus 로고    scopus 로고
    • Anti-malarial effect of histone deacetylation inhibitors and mammalian tumour cytodifferentiating agents
    • DOI 10.1016/S0020-7519(00)00043-6, PII S0020751900000436
    • K.T. Andrews, A. Walduck, M.J. Kelso, D.P. Fairlie, A. Saul, and P.G. Parsons Anti-malarial effect of histone deacetylation inhibitors and mammalian tumour cytodifferentiating agents Int J Parasitol 30 6 2000 761 768 (Pubitemid 30336456)
    • (2000) International Journal for Parasitology , vol.30 , Issue.6 , pp. 761-768
    • Andrews, K.T.1    Walduck, A.2    Kelso, M.J.3    Fairlie, D.P.4    Saul, A.5    Parsons, P.G.6
  • 17
    • 0034326799 scopus 로고    scopus 로고
    • Apicidin, a histone deacetylase inhibitor, inhibits proliferation of tumor cells via induction of p21WAF1/Cip1 and gelsolin
    • J.W. Han, S.H. Ahn, S.H. Park, S.Y. Wang, G.U. Bae, and D.W. Seo Apicidin, a histone deacetylase inhibitor, inhibits proliferation of tumor cells via induction of p21WAF1/Cip1 and gelsolin Cancer Res 60 21 2000 6068 6074
    • (2000) Cancer Res , vol.60 , Issue.21 , pp. 6068-6074
    • Han, J.W.1    Ahn, S.H.2    Park, S.H.3    Wang, S.Y.4    Bae, G.U.5    Seo, D.W.6
  • 18
    • 33847796188 scopus 로고    scopus 로고
    • Apicidin, a novel histone deacetylase inhibitor, has profound anti-growth activity in human endometrial and ovarian cancer cells
    • T. Ueda, N. Takai, M. Nishida, K. Nasu, and H. Narahara Apicidin, a novel histone deacetylase inhibitor, has profound anti-growth activity in human endometrial and ovarian cancer cells Int J Mol Med 19 2 2000 301 308
    • (2000) Int J Mol Med , vol.19 , Issue.2 , pp. 301-308
    • Ueda, T.1    Takai, N.2    Nishida, M.3    Nasu, K.4    Narahara, H.5
  • 19
    • 40949162039 scopus 로고    scopus 로고
    • Modulation of cell cycles and apoptosis by apicidin in estrogen receptor (ER)-positive and -negative human breast cancer cells
    • J.Y. Im, H. Park, K.W. Kang, W.S. Choi, and H.S. Kim Modulation of cell cycles and apoptosis by apicidin in estrogen receptor (ER)-positive and -negative human breast cancer cells Chem Biol Interact 172 3 2008 235 244
    • (2008) Chem Biol Interact , vol.172 , Issue.3 , pp. 235-244
    • Im, J.Y.1    Park, H.2    Kang, K.W.3    Choi, W.S.4    Kim, H.S.5
  • 20
    • 78751556979 scopus 로고    scopus 로고
    • Autophagy as a therapeutic target in cancer
    • N. Chen, and V. Karantza Autophagy as a therapeutic target in cancer Cancer Biol Ther 11 2 2011 157 168
    • (2011) Cancer Biol Ther , vol.11 , Issue.2 , pp. 157-168
    • Chen, N.1    Karantza, V.2
  • 21
    • 69949106925 scopus 로고    scopus 로고
    • The double-edged sword of autophagy modulation in cancer
    • W. Eileen, and S.D. Robert The double-edged sword of autophagy modulation in cancer Clin Cancer Res 15 17 2009 5308 5316
    • (2009) Clin Cancer Res , vol.15 , Issue.17 , pp. 5308-5316
    • Eileen, W.1    Robert, S.D.2
  • 22
    • 27744460985 scopus 로고    scopus 로고
    • Characterization of newly established oral cancer cell lines derived from six squamous cell carcinoma and two mucoepidermoid carcinoma cells
    • E.J. Lee, J. Kim, S.A. Lee, E.J. Kim, Y.C. Chun, and M.H. Ryu Characterization of newly established oral cancer cell lines derived from six squamous cell carcinoma and two mucoepidermoid carcinoma cells Exp Mol Med 37 5 2005 379 390 (Pubitemid 41597251)
    • (2005) Experimental and Molecular Medicine , vol.37 , Issue.5 , pp. 379-390
    • Lee, E.J.1    Kim, J.2    Lee, S.A.3    Kim, E.-J.4    Chun, Y.-C.5    Ryu, M.H.6    Yook, J.-I.7
  • 23
    • 77958609008 scopus 로고    scopus 로고
    • Autophagy inhibition enhances sulforaphane-induced apoptosis in human breast cancer cells
    • S. Kanematsu, N. Uehara, H. Miki, K. Yoshizawa, A. Kawanaka, and T. Yuri Autophagy inhibition enhances sulforaphane-induced apoptosis in human breast cancer cells Anticancer Res 30 9 2010 3381 3390
    • (2010) Anticancer Res , vol.30 , Issue.9 , pp. 3381-3390
    • Kanematsu, S.1    Uehara, N.2    Miki, H.3    Yoshizawa, K.4    Kawanaka, A.5    Yuri, T.6
  • 24
    • 67651170387 scopus 로고    scopus 로고
    • Apicidin induces apoptosis via cytochrome C-mediated intrinsic pathway in human ovarian cancer cells
    • M.Y. Ahn, Y.J. Na, J.W. Lee, B.M. Lee, and H.S. Kim Apicidin induces apoptosis via cytochrome C-mediated intrinsic pathway in human ovarian cancer cells Biomol Ther 17 1 2009 17 24
    • (2009) Biomol Ther , vol.17 , Issue.1 , pp. 17-24
    • Ahn, M.Y.1    Na, Y.J.2    Lee, J.W.3    Lee, B.M.4    Kim, H.S.5
  • 25
    • 77955581767 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: Advancing therapeutic strategies in hematological and solid malignancies
    • L. Ellis, and R. Pili Histone deacetylase inhibitors: advancing therapeutic strategies in hematological and solid malignancies Pharmaceuticals (Basel) 3 8 2010 2411 2469
    • (2010) Pharmaceuticals (Basel) , vol.3 , Issue.8 , pp. 2411-2469
    • Ellis, L.1    Pili, R.2
  • 26
    • 62549116922 scopus 로고    scopus 로고
    • Mechanism of apicidin-induced cell cycle arrest and apoptosis in Ishikawa human endometrial cancer cells
    • M.Y. Ahn, J.W. Lee, Y.J. Na, W.S. Choi, B.M. Lee, and K.W. Kang Mechanism of apicidin-induced cell cycle arrest and apoptosis in Ishikawa human endometrial cancer cells Chem Biol Interact 179 2-3 2009 169 177
    • (2009) Chem Biol Interact , vol.179 , Issue.23 , pp. 169-177
    • Ahn, M.Y.1    Lee, J.W.2    Na, Y.J.3    Choi, W.S.4    Lee, B.M.5    Kang, K.W.6
  • 27
    • 77956404377 scopus 로고    scopus 로고
    • Eaten alive: A history of macro-autophagy
    • Z. Yang, and D.J. Klionsky Eaten alive: a history of macro-autophagy Nat Cell Biol 12 9 2010 814 822
    • (2010) Nat Cell Biol , vol.12 , Issue.9 , pp. 814-822
    • Yang, Z.1    Klionsky, D.J.2
  • 29
    • 67449127083 scopus 로고    scopus 로고
    • Cytotoxicity mediated by histone deacetylase inhibitors in cancer cells: Mechanisms and potential clinical implications
    • D.S. Schrump Cytotoxicity mediated by histone deacetylase inhibitors in cancer cells: mechanisms and potential clinical implications Clin Cancer Res 15 12 2009 3947 3957
    • (2009) Clin Cancer Res , vol.15 , Issue.12 , pp. 3947-3957
    • Schrump, D.S.1
  • 30
    • 79952270884 scopus 로고    scopus 로고
    • HDACs link the DNA damage response, processing of double-strand breaks and autophagy
    • T. Robert, F. Vanoli, I. Chiolo, G. Shubassi, K.A. Bernstein, and R. Rothstein HDACs link the DNA damage response, processing of double-strand breaks and autophagy Nature 471 7336 2011 74 79
    • (2011) Nature , vol.471 , Issue.7336 , pp. 74-79
    • Robert, T.1    Vanoli, F.2    Chiolo, I.3    Shubassi, G.4    Bernstein, K.A.5    Rothstein, R.6
  • 31
    • 57149105528 scopus 로고    scopus 로고
    • SAHA induces caspase-independent, autophagic cell death of endometrial stromal sarcoma cells by influencing the mTOR pathway
    • A. Hrzenjak, M.L. Kremser, B. Strohmeier, F. Moinfar, K. Zatloukal, and H. Denk SAHA induces caspase-independent, autophagic cell death of endometrial stromal sarcoma cells by influencing the mTOR pathway J Pathol 216 4 2008 495 504
    • (2008) J Pathol , vol.216 , Issue.4 , pp. 495-504
    • Hrzenjak, A.1    Kremser, M.L.2    Strohmeier, B.3    Moinfar, F.4    Zatloukal, K.5    Denk, H.6
  • 32
    • 58149390639 scopus 로고    scopus 로고
    • Induction of autophagy in malignant rhabdoid tumor cells by the histone deacetylase inhibitor FK228 through AIF translocation
    • M. Watanabe, S. Adachi, H. Matsubara, T. Imai, Y. Yui, and Y. Mizushima Induction of autophagy in malignant rhabdoid tumor cells by the histone deacetylase inhibitor FK228 through AIF translocation Int J Cancer 124 1 2009 55 67
    • (2009) Int J Cancer , vol.124 , Issue.1 , pp. 55-67
    • Watanabe, M.1    Adachi, S.2    Matsubara, H.3    Imai, T.4    Yui, Y.5    Mizushima, Y.6
  • 33
    • 79956014819 scopus 로고    scopus 로고
    • Induction of lysosomal dilatation, arrested autophagy, and cell death by chloroquine in cultured ARPE-19 cells
    • Y.H. Yoon, K.S. Cho, J.J. Hwang, S.J. Lee, J.A. Choi, and J.Y. Koh Induction of lysosomal dilatation, arrested autophagy, and cell death by chloroquine in cultured ARPE-19 cells Invest Ophthalmol Vis Sci 51 11 2010 6030 6037
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , Issue.11 , pp. 6030-6037
    • Yoon, Y.H.1    Cho, K.S.2    Hwang, J.J.3    Lee, S.J.4    Choi, J.A.5    Koh, J.Y.6
  • 34
    • 34548188741 scopus 로고    scopus 로고
    • Self-eating and self-killing: Crosstalk between autophagy and apoptosis
    • DOI 10.1038/nrm2239, PII NRM2239
    • M.C. Maiuri, E. Zalckvar, A. Kimchi, and G. Kroemer Self-eating and self-killing: crosstalk between autophagy and apoptosis Nat Rev Mol Cell Biol 8 9 2007 741 752 (Pubitemid 47312826)
    • (2007) Nature Reviews Molecular Cell Biology , vol.8 , Issue.9 , pp. 741-752
    • Maiuri, M.C.1    Zalckvar, E.2    Kimchi, A.3    Kroemer, G.4
  • 35
    • 34347394714 scopus 로고    scopus 로고
    • Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHAto overcome Bcr-Abl-mediated drug resistance
    • DOI 10.1182/blood-2006-10-050260
    • J.S. Carew, S.T. Nawrocki, C.N. Kahue, H. Zhang, C. Yang, and L. Chung Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl-mediated drug resistance Blood 110 1 2007 313 322 (Pubitemid 47026849)
    • (2007) Blood , vol.110 , Issue.1 , pp. 313-322
    • Carew, J.S.1    Nawrocki, S.T.2    Kahue, C.N.3    Zhang, H.4    Yang, C.5    Chung, L.6    Houghton, J.A.7    Huang, P.8    Giles, F.J.9    Cleveland, J.L.10
  • 36
    • 77952766891 scopus 로고    scopus 로고
    • Autophagy: Assays and artifacts
    • S. Barth, D. Glick, and K.F. Macleod Autophagy: assays and artifacts J Pathol 221 2 2010 117 124
    • (2010) J Pathol , vol.221 , Issue.2 , pp. 117-124
    • Barth, S.1    Glick, D.2    MacLeod, K.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.