Mechanism of apicidin-induced cell cycle arrest and apoptosis in Ishikawa human endometrial cancer cells

Chemico-Biological Interactions

Volumn 179, Issue 2-3, 2009, Pages 169-177

  Ahn, Mee Young ^a   Lee, Jaewon ^a   Na, Yong Jin ^b   Choi, Wahn Soo ^c   Lee, Byung Mu ^d   Kang, Keon Wook ^e   Kim, Hyung Sik ^a  

^a Pusan National University   (South Korea)

^b Pusan National University School of Medicine   (South Korea)

^c Konkuk University   (South Korea)

^d Sungkyunkwan University   (South Korea)

^e Chosun University   (South Korea)

Author keywords

Apicidin; Apoptosis; Caspase activity; cytochrome c release; Histone deacetylase (HDAC) inhibitor; Ishikawa cells

Indexed keywords

APICIDIN; CASPASE 3; CYCLIN A; CYCLIN B1; CYCLIN D1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN E; CYTOCHROME C; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL POPULATION; CELL PROLIFERATION; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENDOMETRIUM CANCER; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; NICK END LABELING; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN SECRETION; UPREGULATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CELL CYCLE; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASES; CYCLINS; CYTOCHROMES C; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; ENDOMETRIAL NEOPLASMS; FEMALE; G1 PHASE; GENE EXPRESSION REGULATION, NEOPLASTIC; HISTONES; HUMANS; PEPTIDES, CYCLIC; PROTO-ONCOGENE PROTEINS C-BCL-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR CELLS, CULTURED;

EID: 62549116922     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2008.11.011     Document Type: Article

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