Targeting granzyme B to tumor cells using a yoked human chorionic gonadotropin

Cancer Chemotherapy and Pharmacology

Volumn 68, Issue 4, 2011, Pages 979-990

  Kanatani, Isao ^a   Lin, Xinjian ^a   Yuan, Xiaoqin ^a   Manorek, Gerald ^a   Shang, Xiying ^a   Cheung, Lawrence H ^b   Rosenblum, Michael G ^b   Howell, Stephen B ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Granzyme B; Human chorionic gonadotropin; Luteinizing hormone receptor; Targeted therapy

Indexed keywords

CASPASE 3; GRANZYME B; GRANZYME B YOKED HUMAN CHORIONIC GONADOTROPIN FUSION PROTEIN; HORMONOTOXIN; LUTEINIZING HORMONE RECEPTOR; SERINE PROTEINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BINDING AFFINITY; CANCER CELL; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG CYTOTOXICITY; ENZYME ACTIVITY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HORMONE RECEPTOR INTERACTION; IN VITRO STUDY; INSECT CELL; INTERNALIZATION; LEYDIG CELL; MOUSE; NONHUMAN; OVARY CANCER; PRIORITY JOURNAL; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CELL LINE; CELL LINE, TUMOR; CELLS, CULTURED; CHORIONIC GONADOTROPIN; DRUG DELIVERY SYSTEMS; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; GRANZYMES; HUMANS; MICE; MICROSCOPY, CONFOCAL; OVARIAN NEOPLASMS; PROTEIN BINDING; RECEPTORS, LH; SPODOPTERA;

EID: 80054762432     PISSN: 03445704     EISSN: 14320843     Source Type: Journal    
DOI: 10.1007/s00280-011-1573-4     Document Type: Article

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