Influence of polymer adjuvants on the ultrasound-mediated transfection of cells in culture

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 72, Issue 3, 2009, Pages 567-573

  Mehier Humbert, Sophie ^a,b   Bettinger, Thierry ^b   Yan, Feng ^b   Guy, Richard ^a,c  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b Bracco Suisse SA   (Switzerland)

^c University of Bath   (United Kingdom)

Author keywords

Cell viability; Membrane fluidization; Polymer adjuvants; Sonoporation; Transfection; Ultrasound contrast agents

Indexed keywords

DNA; ECHO CONTRAST MEDIUM; GREEN FLUORESCENT PROTEIN; MACROGOL; MACROGOL 4000; PHOSPHOLIPID; POLOXAMER; POLYMER;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL MEMBRANE; CELL SUSPENSION; CELL VIABILITY; CONTROLLED STUDY; CULTURE MEDIUM; DNA TRANSFECTION; DRUG DELIVERY SYSTEM; FLUIDIZATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; NONHUMAN; PHYSICAL CHEMISTRY; RAT; ULTRASOUND;

ADJUVANTS, PHARMACEUTIC; ANIMALS; CELL LINE; CELL SURVIVAL; CELLS; GREEN FLUORESCENT PROTEINS; HUMANS; POLYMERS; RATS; TRANSFECTION; TUMOR CELLS, CULTURED; ULTRASONICS;

EID: 67449110720     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2009.02.012     Document Type: Article

References (43)

1. Newman C.M., Lawrie A., Brisken A.F., and Cumberland D.C. Ultrasound gene therapy: on the road from concept to reality. Echocardiography 18 4 (2001) 339-347
2. Miller D.L., Pislaru S.V., and Greenleaf Sonoporation J.E. Mechanical DNA delivery by ultrasonic cavitation. Somat. Cell. Mol. Genet. 27 1-6 (2002) 115-134 Nov
3. Tachibana K. Emerging technologies in therapeutic ultrasound: thermal ablation to gene delivery. Hum. Cell. 17 1 (2004) 7-15 Mar
4. Pitt W.G., Husseini G.A., and Staples B.J. Ultrasonic drug delivery - a general review. Expert. Opin. Drug Deliv. 1 1 (2004) 37-56
5. Newman C.M., and Bettinger T. Gene therapy progress and prospects: ultrasound for gene transfer. Gene Ther. 14 6 (2007) 465-475 Mar
6. Mehier-Humbert S., Bettinger T., Yan F., and Guy R.H. Ultrasound-mediated gene delivery: kinetics of plasmid internalization and gene expression. J Control Release 104 1 (2005) 203-211 May 5
7. Mehier-Humbert S., Bettinger T., Yan F., and Guy R.H. Plasma membrane poration induced by ultrasound exposure: implication for drug delivery. J Control Release 104 1 (2005) 213-222 May 5
8. Mehier-Humbert S., Yan F., Frinking P., Schneider M., Guy R.H., and Bettinger T. Ultrasound-mediated gene delivery: influence of contrast agent on transfection. Bioconjug. Chem. 18 3 (2007) 652-662 May-Jun
9. Batrakova E.V., Li S., Vinogradov S.V., Alakhov V.Y., Miller D.W., and Kabanov A.V. Mechanism of Pluronic effect on P-glycoprotein efflux system in blood-brain barrier: contributions of energy depletion and membrane fluidization. J. Pharmacol. Exp. Ther. 299 2 (2001) 483-493 Nov
10. Saha P., and Kou J.H. Effect of solubilizing excipients on permeation of poorly water-soluble compounds across Caco-2 cell monolayers. Eur. J. Pharm. Biopharm. 50 3 (2000) 403-411 Nov
11. Koob A.O., and Borgens R.B. Polyethylene glycol treatment after traumatic brain injury reduces beta-amyloid precursor protein accumulation in degenerating axons. J. Neurosci. Res. 83 8 (2006) 1558-1563
12. Shi R., and Borgens R.B. Anatomical repair of nerve membranes in crushed mammalian spinal cord with polyethylene glycol. J. Neurocytol. 29 9 (2000) 633-643 Sep
13. Stefanovich P., Ezzell R.M., Sheehan S.J., Tompkins R.G., Yarmush M.L., and Toner M. Effects of hypothermia on the function, membrane integrity, and cytoskeletal structure of hepatocytes. Cryobiology 32 4 (1995) 389-403
14. Regev R., Katzir H., Yeheskely-Hayon D., and Eytan G.D. Modulation of P-glycoprotein-mediated multidrug resistance by acceleration of passive drug permeation across the plasma membrane. FEBS J. 274 23 (2007) 6204-6214
15. Batrakova E.V., Vinogradov S.V., Robinson S.M., Niehoff M.L., WA B., and AV K. Polypeptide point modifications with fatty acid and amphiphilic block copolymers for enhanced brain delivery. Bioconjug. Chem. 16 4 (2005) 793-802
16. Kabanov A., Zhu J., and Alakhov V. Pluronic block copolymers for gene delivery. Adv. Genet. 53 (2005) 231-261
17. Klebe R.J., Hanson D.P., Harriss J.V., and Bentley K.L. Uptake by cells of nucleic acids promoted by compounds sharing the pleiotropic effects of poly(ethylene glycol). Teratog. Carcinog. Mutagen. 6 3 (1986) 245-250
18. Melik-Nubarov N.S., Pomaz O.O., Dorodnych T.Y., Badun G.A., Ksenofontov A.L., Schemchukova O.B., et al. Interaction of tumor and normal blood cells with ethylene oxide and propylene oxide block copolymers. FEBS Lett. 446 1 (1999) 194-198
19. Kaps M., Schaffer P., Beller K.D., Seidel G., Bliesath H., and Diletti E. Characteristics of transcranial Doppler signal enhancement using a phospholipid-containing echocontrast agent. Stroke 28 5 (1997) 1006-1008
20. Chen Y.C., Liang H.D., Zhang Q.P., Blomley M.J., and Lu Q.L. Pluronic block copolymers: novel functions in ultrasound-mediated gene transfer and against cell damage. Ultrasound Med. Biol. 32 1 (2006) 131-137
21. Batrakova E.V., Li S., Alakhov V.Y., Miller D.W., and Kabanov A.V. Optimal structure requirements for Pluronic block copolymers in modifying P-glycoprotein drug efflux transporter activity in bovine brain microvessel endothelial cells. J. Pharmacol. Exp. Ther. 304 2 (2003) 845-854
22. Baron G.S., and Caughey B. Effect of glycosylphosphatidylinositol anchor-dependent and -independent prion protein association with model raft membranes on conversion to the protease-resistant isoform. J. Biol. Chem. 278 17 (2003) 14883-14892
23. Murad K.L., Mahany K.L., Brugnara C., Kuypers F.A., Eaton J.W., and Scott M.D. Structural and functional consequences of antigenic modulation of red blood cells with methoxypoly(ethylene glycol). Blood 93 6 (1999) 2121-2127
24. 2+independent alpha-amylase of Geobacillus thermoleovorans by surfactants. Lett. Appl. Microbiol. 36 4 (2003) 191-196
25. Lemieux P., Guerin N., Paradis G., Proulx R., Chistyakova L., Kabanov A., et al. A combination of poloxamers increases gene expression of plasmid DNA in skeletal muscle. Gene Ther. 7 11 (2000) 986-991
26. S. Humbert, Mechanistic investigation of microbubble-mediated sonoporation for intracellular gene delivery, Dissertation, Faculté des Sciences de l'Université de Genève, 2005.
27. Han L.M., Guo J., Zhang L.J., Wang Q.S., and Fang X.L. Pharmacokinetics and biodistribution of polymeric micelles of paclitaxel with Pluronic P123. Acta Pharmacol. Sin. 27 6 (2006) 747-753
28. M. Ash, I. Ash, Handbook of Pharmaceutical Additives, Synapse Information Resources Inc. ed., 2002.
29. Ohno H., Shimidzu N., Tsuchida E., Sasakawa S., and Honda K. Fluorescence polarization study on the increase of membrane fluidity of human erythrocyte ghosts induced by synthetic water-soluble polymers. Biochim. Biophys. Acta 649 2 (1981) 221-228
30. Kuo J.H. Effect of Pluronic-block copolymers on the reduction of serum-mediated inhibition of gene transfer of polyethyleneimine-DNA complexes. Biotechnol. Appl. Biochem. 37 Pt 3 (2003) 267-271
31. Kabanov A.V., Lemieux P., Vinogradov S., and Alakhov V. Pluronic block copolymers: novel functional molecules for gene therapy. Adv. Drug Deliv. Rev. 54 2 (2002) 223-233
32. Lee R.C., River L.P., Pan F.S., Ji L., and Wollmann R.L. Surfactant-induced sealing of electropermeabilized skeletal muscle membranes in vivo. Proc. Natl. Acad. Sci. USA 89 10 (1992) 4524-4528
33. Lee R.C., Canaday D.J., and Hammer S.M. Transient and stable ionic permeabilization of isolated skeletal muscle cells after electrical shock. J. Burn Care Rehabil. 14 5 (1993) 528-540
34. Kabanov A., Batrakova E., and Alakhov V. Pluronic block copolymers as novel polymer therapeutics for drug and gene delivery. J. Control Release 82 (2002) 189-212
35. Lopes J.R., and Watson L. Investigation of self-assembly and micelle polarity for a wide range of ethylene oxide-propylene oxide-ethylene oxide block copolymers in water. Langmuir 14 (1998) 750-756
36. Budker V.G., Slattum P.M., Monahan S.D., and Wolff J.A. Entrapment and condensation of DNA in neutral reverse micelles. Biophys. J. 82 3 (2002) 1570-1579
37. Kakizawa Y., and Kataoka K. Block copolymer micelles for delivery of gene and related compounds. Adv. Drug Deliv. Rev. 54 2 (2002) 203-222
38. Shi W.T., Forsberg F., Tornes A., Ostensen J., and Goldberg B.B. Destruction of contrast microbubbles and the association with inertial cavitation. Ultrasound Med. Biol. 26 6 (2000) 1009-1019
39. Ross P.C., and Hui S.W. Polyethylene glycol enhances lipoplex-cell association and lipofection. Biochim. Biophys. Acta 1421 2 (1999) 273-283
40. MacDonald R.I. Membrane fusion due to dehydration by polyethylene glycol, dextran, or sucrose. Biochemistry 24 15 (1985) 4058-4066
41. Herrmann A., Arnold K., Pratsch L., and Lassmann G. Influence of polyethylene glycol on the structure of the erythrocyte membrane: an ESR study. Biomed.Biochim. Acta 42 9 (1983) 1151-1155
42. Yang Q., Guo Y., Li L., and Hui S.W. Effects of lipid headgroup and packing stress on poly(ethylene glycol)-induced phospholipid vesicle aggregation and fusion. Biophys. J. 73 1 (1997) 277-282
43. Lesage D., Cao A., Briane D., Lievre N., Coudert R., Raphael M., et al. Evaluation and optimization of DNA delivery into gliosarcoma 9L cells by a cholesterol-based cationic liposome. Biochim. Biophys. Acta 1564 2 (2002) 393-402