Ox-PAPC activation of PMET system increases expression of heme oxygenase-1 in human aortic endothelial cell

Journal of Lipid Research

Volumn 50, Issue 2, 2009, Pages 265-274

  Lee, Sangderk ^a   Li, Rongsong ^a   Kim, Brandon ^a   Palvolgyi, Roland ^a   H, Tiffany ^a   Yang, Qian Zhou ^a   Xu, Jason ^a   Szeto, Wan Lam ^a   Honda, Henry ^b   Berliner, Judith A ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Atherosclerosis; Endothelium; Nrf2; Oxidized 1 palmitoyl 2 arachidonyl sn glycerol 3 phosphocholine; Plasma membrane electron transport

Indexed keywords

1 PALMITOYL 2 ARACHIDONYL SN GLYCEROL 3 PHOSPHOCHOLINE; HEME OXYGENASE 1; PHOSPHORYLCHOLINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE) 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; NOX1 PROTEIN, HUMAN; NQO1 PROTEIN, HUMAN; OXIDIZED L ALPHA 1 PALMITOYL 2 ARACHIDONOYL SN GLYCERO 3 PHOSPHORYLCHOLINE; OXIDIZED-L-ALPHA-1-PALMITOYL-2-ARACHIDONOYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE; PHOSPHATIDYLCHOLINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

AORTA; ARTICLE; CELL METABOLISM; CELL STIMULATION; CONTROLLED STUDY; ELECTRON TRANSPORT; ENDOTHELIUM CELL; ENZYME INDUCTION; HUMAN; HUMAN CELL; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; BIOLOGICAL MODEL; CELL CULTURE; CELL MEMBRANE; CYTOLOGY; DRUG EFFECT; GENE EXPRESSION; GENETICS; METABOLISM;

AORTA; CELL MEMBRANE; CELLS, CULTURED; ELECTRON TRANSPORT; ENDOTHELIAL CELLS; GENE EXPRESSION; HEME OXYGENASE-1; HUMANS; MODELS, BIOLOGICAL; NAD(P)H DEHYDROGENASE (QUINONE); NADPH OXIDASE; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PHOSPHATIDYLCHOLINES;

EID: 64749110692     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M800317-JLR200     Document Type: Article

References (44)

1. Yla-Herttuala, S., W. Palinski, M. E. Rosenfeld, S. Parthasarathy, T. E. Carew, S. Butler, J. L. Witztum, and D. Steinberg. 1989. Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man. J. Clin. Invest. 84: 1086-1095.
2. Subbanagounder, G., N. Leitinger, D. C. Schwenke, J. W. Wong, H. Lee, C. Rizza, A. D. Watson, K. F. Faull, A. M. Fogelman, and J. A. Berliner. 2000. Determinants of bioactivity of oxidized phospholipids. Specific oxidized fatty acyl groups at the sn-2 position. Arterioscler. Thromb. Vasc. Biol. 20: 2248-2254.
3. Watson, A. D., G. Subbanagounder, D. S. Welsbie, K. F. Faull, M. Navab, M. E. Jung, A. M. Fogelman, and J. A. Berliner. 1999. Structural identification of a novel pro-inflammatory epoxyisoprostane phospholipid in mildly oxidized low density lipoprotein. J. Biol. Chem. 274: 24787-24798.
4. Gargalovic, P. S., M. Imura, B. Zhang, N. M. Gharavi, M. J. Clark, J. Pagnon, W. P. Yang, A. He, A. Truong, S. Patel, et al. 2006. Identification of inflammatory gene modules based on variations of human endothelial cell responses to oxidized lipids. Proc. Natl. Acad. Sci. USA. 103: 12741-12746.
5. Gargalovic, P. S., N. M. Gharavi, M. J. Clark, J. Pagnon, W. P. Yang, A. He, A. Truong, T. Baruch-Oren, J. A. Berliner, T. G. Kirchgessner, et al. 2006. The unfolded protein response is an important regulator of inflammatory genes in endothelial cells. Arterioscler. Thromb. Vasc. Biol. 26: 2490-2496.
6. Subbanagounder, G., J. W. Wong, H. Lee, K. F. Faull, E. Miller, J. L. Witztum, and J. A. Berliner. 2002. Epoxyisoprostane and epoxycyclopentenone phospholipids regulate monocyte chemotactic protein-1 and interleukin-8 synthesis. Formation of these oxidized phospholipids in response to interleukin-1beta. J. Biol. Chem. 277: 7271-7281.
7. Kronke, G., V. N. Bochkov, J. Huber, F. Gruber, S. Bluml, A. Furnkranz, A. Kadl, B. R. Binder, and N. Leitinger. 2003. Oxidized phospholipids induce expression of human heme oxygenase-1 involving activation of cAMP-responsive element-binding protein. J. Biol. Chem. 278: 51006-51014.
8. Jyrkkanen, H. K., E. Kansanen, M. Inkala, A. M. Kivela, H. Hurttila, S. E. Heinonen, G. Goldsteins, S. Jauhiainen, S. Tiainen, H. Makkonen, et al. 2008. Nrf2 regulates antioxidant gene expression evoked by oxidized phospholipids in endothelial cells and murine arteries in vivo. Circ. Res. 103: e1-e9.
9. Morse, D., and A. M. Choi. 2005. Heme oxygenase-1: from bench to bedside. Am. J. Respir. Crit. Care Med. 172: 660-670.
10. Gharavi, N. M., P. S. Gargalovic, I. Chang, J. A. Araujo, M. J. Clark, W. L. Szeto, A. D. Watson, A. J. Lusis, and J. A. Berliner. 2007. High-density lipoprotein modulates oxidized phospholipid signaling in human endothelial cells from proinflammatory to anti-inflammatory. Arterioscler. Thromb. Vasc. Biol. 27: 1346-1353.
11. Srisook, K., C. Kim, and Y. N. Cha. 2005. Molecular mechanisms involved in enhancing HO-1 expression: de-repression by heme and activation by Nrf2, the "one-two" punch. Antioxid. Redox Signal. 7: 1674-1687.
12. Kang, K. W., S. J. Lee, and S. G. Kim. 2005. Molecular mechanism of nrf2 activation by oxidative stress. Antioxid. Redox Signal. 7: 1664-1673.
13. Sun, Z., S. Zhang, J. Y. Chan, and D. D. Zhang. 2007. Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2. Mol. Cell. Biol. 27: 6334-6349.
14. Herst, P. M., A. S. Tan, D. J. Scarlett, and M. V. Berridge. 2004. Cell surface oxygen consumption by mitochondrial gene knockout cells. Biochim. Biophys. Acta. 1656: 79-87.
15. Herst, P. M., and M. V. Berridge. 2007. Cell surface oxygen consumption: a major contributor to cellular oxygen consumption in glycolytic cancer cell lines. Biochim. Biophys. Acta. 1767: 170-177.
16. Berridge, M. V., P. M. Herst, and A. S. Tan. 2005. Tetrazolium dyes as tools in cell biology: new insights into their cellular reduction. Biotechnol. Annu. Rev. 11: 127-152.
17. Scarlett, D. J., P. M. Herst, and M. V. Berridge. 2005. Multiple proteins with single activities or a single protein with multiple activities: the conundrum of cell surface NADH oxidoreductases. Biochim. Biophys. Acta. 1708: 108-119.
18. Herst, P. M., and M. V. Berridge. 2006. Plasma membrane electron transport: a new target for cancer drug development. Curr. Mol. Med. 6: 895-904.
19. Ying, W. 2008. NAD1/NADH and NADP1/NADPH in cellular functions and cell death: regulation and biological consequences. Antioxid. Redox Signal. 10: 179-206.
20. Morre, D. J. 2004. Quinone oxidoreductases of the plasma membrane. Methods Enzymol. 378: 179-199.
21. Sun, I. L., E. E. Sun, F. L. Crane, D. J. Morre, A. Lindgren, and H. Low. 1992. Requirement for coenzyme Q in plasma membrane electron transport. Proc. Natl. Acad. Sci. USA. 89: 11126-11130.
22. Morre, D. J., and D. M. Morre. 2006. Aging-related cell surface ECTO-NOX protein, arNOX, a preventive target to reduce atherogenic risk in the elderly. Rejuvenation Res. 9: 231-236.
23. Morre, D. M., F. Guo, and D. J. Morre. 2003. An aging-related cell surface NADH oxidase (arNOX) generates superoxide and is inhibited by coenzyme Q. Mol. Cell. Biochem. 254: 101-109.
24. Rodriguez-Alonso, J., R. Montanez, L. Rodriguez-Caso, and M. A. Medina. 2008. Homocysteine is a potent modulator of plasma membrane electron transport systems. J. Bioenerg. Biomembr. 40: 45-51.
25. Jung, M. E., J. A. Berliner, D. Angst, D. Yue, L. Koroniak, A. D. Watson, and R. Li. 2005. Total synthesis of the epoxy isoprostane phospholipids PEIPC and PECPC. Org. Lett. 7: 3933-3935.
26. Liao, F., J. A. Berliner, M. Mehrabian, M. Navab, L. L. Demer, A. J. Lusis, and A. M. Fogelman. 1991. Minimally modified low density lipoprotein is biologically active in vivo in mice. J. Clin. Invest. 87: 2253-2257.
27. Navab, M., G. P. Hough, L. W. Stevenson, D. C. Drinkwater, H. Laks, and A. M. Fogelman. 1988. Monocyte migration into the subendothelial space of a coculture of adult human aortic endothelial and smooth muscle cells. J. Clin. Invest. 82: 1853-1863.
28. Zimman, A., K. P. Mouillesseaux, T. Le, N. M. Gharavi, A. Ryvkin, T. G. Graeber, T. T. Chen, A. D. Watson, and J. A. Berliner. 2007. Vascular endothelial growth factor receptor 2 plays a role in the activation of aortic endothelial cells by oxidized phospholipids. Arterioscler. Thromb. Vasc. Biol. 27: 332-338.
29. Li, R., W. Chen, R. Yanes, S. Lee, and J. A. Berliner. 2007. OKL38 is an oxidative stress response gene stimulated by oxidized phospholipids. J. Lipid Res. 48: 709-715.
30. Gharavi, N. M., N. A. Baker, K. P. Mouillesseaux, W. Yeung, H. M. Honda, X. Hsieh, M. Yeh, E. J. Smart, and J. A. Berliner. 2006. Role of endothelial nitric oxide synthase in the regulation of SREBP activation by oxidized phospholipids. Circ. Res. 98: 768-776.
31. Dikalov, S., K. K. Griendling, and D. G. Harrison. 2007. Measurement of reactive oxygen species in cardiovascular studies. Hypertension. 49: 717-727.
32. Chakraborty, S., and V. Massey. 2002. Reaction of reduced flavins and flavoproteins with diphenyliodonium chloride. J. Biol. Chem. 277: 41507-41516.
33. Asher, G., O. Dym, P. Tsvetkov, J. Adler, and Y. Shaul. 2006. The crystal structure of NAD(P)H quinone oxidoreductase 1 in complex with its potent inhibitor dicoumarol. Biochemistry. 45: 6372-6378.
34. Forthoffer, N., C. Gomez-Diaz, R. I. Bello, M. I. Buron, S. F. Martin, J. C. Rodriguez-Aguilera, P. Navas, and J. M. Villalba. 2002. A novel plasma membrane quinone reductase and NAD(P)H:quinone oxidoreductase 1 are upregulated by serum withdrawal in human promyelocytic HL-60 cells. J. Bioenerg. Biomembr. 34: 209-219.
35. Rouhanizadeh, M., J. Hwang, R. E. Clempus, L. Marcu, B. Lassegue, A. Sevanian, and T. K. Hsiai. 2005. Oxidized-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine induces vascular endothelial superoxide production: implication of NADPH oxidase. Free Radic. Biol. Med. 39: 1512-1522.
36. Yeh, M., N. M. Gharavi, J. Choi, X. Hsieh, E. Reed, K. P. Mouillesseaux, A. L. Cole, S. T. Reddy, and J. A. Berliner. 2004. Oxidized phospholipids increase interleukin 8 (IL-8) synthesis by activation of the c-src/signal transducers and activators of transcription (STAT)3 pathway. J. Biol. Chem. 279: 30175-30181.
37. Kronke, G., A. Kadl, E. Ikonomu, S. Bluml, A. Furnkranz, I. J. Sarembock, V. N. Bochkov, M. Exner, B. R. Binder, and N. Leitinger. 2007. Expression of heme oxygenase-1 in human vascular cells is regulated by peroxisome proliferator-activated receptors. Arterioscler. Thromb. Vasc. Biol. 27: 1276-1282.
38. Leitinger, N. 2003. Oxidized phospholipids as modulators of inflammation in atherosclerosis. Curr. Opin. Lipidol. 14: 421-430.
39. Yeh, M., A. L. Cole, J. Choi, Y. Liu, D. Tulchinsky, J. H. Qiao, M. C. Fishbein, A. N. Dooley, T. Hovnanian, K. Mouilleseaux, et al. 2004. Role for sterol regulatory element-binding protein in activation of endothelial cells by phospholipid oxidation products. Circ. Res. 95: 780-788.
40. Hazen, S. L. 2008. Oxidized phospholipids as endogenous pattern recognition ligands in innate immunity. J. Biol. Chem. 283: 15527-15531.
41. Greenberg, M. E., X. M. Li, B. G. Gugiu, X. Gu, J. Qin, R. G. Salomon, and S. L. Hazen. 2008. The lipid whisker model of the structure of oxidized cell membranes. J. Biol. Chem. 283: 2385-2396.
42. Jain, S., M. Thomas, G. P. Kumar, and M. Laloraya. 1993. Programmed lipid peroxidation of biomembranes generating kinked phospholipids permitting local molecular mobility: a peroxidative theory of fluidity management. Biochem. Biophys. Res. Commun. 195: 574-580.
43. Kim, S. M., T. Yamamoto, Y. Todokoro, Y. Takayama, T. Fujiwara, J. S. Park, and H. Akutsu. 2006. Phospholipid-dependent regulation of cytochrome c3-mediated electron transport across membranes. Biophys. J. 90: 506-513.
44. Dhanasekaran, M., and J. Ren. 2005. The emerging role of coenzyme Q-10 in aging, neurodegeneration, cardiovascular disease, cancer and diabetes mellitus. Curr Neurovasc Res. 2: 447-459.