Fluvastatin modulates renal water reabsorption in vivo through increased AQP2 availability at the apical plasma membrane of collecting duct cells

Pflugers Archiv European Journal of Physiology

Volumn 462, Issue 5, 2011, Pages 753-766

  Procino, Giuseppe ^a   Barbieri, Claudia ^a   Carmosino, Monica ^a   Tamma, Grazia ^a   Milano, Serena ^a   De Benedictis, Leonarda ^c   Mola, Maria Grazia ^a   Lazo Fernandez, Yoskaly ^d   Valenti, Giovanna ^a,b   Svelto, Maria ^a,b  

^a UNIVERSITY OF BARI   (Italy)

^b Centro di Eccellenza di Genomica in Campo Biomedico ed Agrario (CEGBA)   (Italy)

^c UNIVERSITY OF BARI MEDICAL SCHOOL   (Italy)

^d NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

Aquaporins; Diabetes insipidus; Diuresis; Epithelial transport; Kidney; Nephrogenic diabetes insipidus; Statins; Vasopressin

Indexed keywords

AQUAPORIN 2; CERIVASTATIN; FLUINDOSTATIN; MEVINOLIN; RAB PROTEIN; RHO FACTOR; ROSUVASTATIN; VASOPRESSIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APICAL MEMBRANE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; IN VITRO STUDY; IN VIVO STUDY; KIDNEY COLLECTING TUBULE; KIDNEY TUBULE ABSORPTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PRENYLATION; PROTEIN TRANSPORT; SINGLE DRUG DOSE; WATER ABSORPTION;

ANIMALS; AQUAPORIN 2; CELL MEMBRANE; DIABETES INSIPIDUS, NEPHROGENIC; FATTY ACIDS, MONOUNSATURATED; INDOLES; KIDNEY TUBULES, COLLECTING; MALE; MICE; MICE, INBRED C57BL; PRENYLATION; RAB GTP-BINDING PROTEINS; RHO-ASSOCIATED KINASES;

EID: 80054726669     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-011-1007-5     Document Type: Article

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