Proximal tubules and podocytes are toxicity targets of bucillamine in a mouse model of drug-induced kidney injury

European Journal of Pharmacology

Volumn 670, Issue 1, 2011, Pages 208-215

  Fujiwara, Yoko ^a   Tsuchiya, Hiroyoshi ^a   Sakai, Nobuya ^b   Shibata, Katsushi ^b   Fujimura, Akio ^a   Koshimizu, Taka Aki ^a  

^a JICHI MEDICAL UNIVERSITY   (Japan)

^b HIMEJI DOKKYO UNIVERSITY   (Japan)

Author keywords

Animal model; Bucillamine; d Penicillamine; DNA microarray; Nephrotoxicity; NGAL (Neutrophil gelatinase associated lipocalin)

Indexed keywords

BUCILLAMINE; CYTOCHROME; CYTOCHROME P450 4A14; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; OXIDOREDUCTASE; PENICILLAMINE; PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9; SERINE PROTEINASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION PROFILING; HEMINEPHRECTOMY; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE DAMAGE; MALE; MEMBRANOUS GLOMERULONEPHRITIS; MOUSE; NEPHROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PODOCYTE; PRIORITY JOURNAL; PROTEIN URINE LEVEL; UPREGULATION;

ACUTE KIDNEY INJURY; ANIMALS; CYSTEINE; DISEASE MODELS, ANIMAL; KIDNEY TUBULES, PROXIMAL; MALE; MICE; MICE, INBRED BALB C; NEPHRECTOMY; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PODOCYTES; PROTEINURIA; TRANSCRIPTOME; UP-REGULATION;

EID: 80054725283     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.08.051     Document Type: Article

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