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Volumn 101, Issue 8, 2011, Pages 1825-1834

Steady states and dynamics of urokinase-mediated plasmin activation in silico and in vitro

Author keywords

[No Author keywords available]

Indexed keywords

PLASMIN; UROKINASE;

EID: 80054713184     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2011.08.054     Document Type: Article
Times cited : (9)

References (52)
  • 1
    • 0029156876 scopus 로고
    • Role of the plasminogen/plasmin system in thrombosis, hemostasis, restenosis and atherosclerosis evaluation in transgenic animals
    • P. Carmeliet, and D. Collen Role of the plasminogen/plasmin system in thrombosis, hemostasis, restenosis and atherosclerosis evaluation in transgenic animals Trends Cardiovasc. Med. 5 1995 117 122
    • (1995) Trends Cardiovasc. Med. , vol.5 , pp. 117-122
    • Carmeliet, P.1    Collen, D.2
  • 2
    • 15844426333 scopus 로고    scopus 로고
    • Plasmin, fibrin degradation and angiogenesis
    • W.D. Thompson, and C.M. Stirk E.B. Smith Plasmin, fibrin degradation and angiogenesis Nat. Med. 2 1996 493
    • (1996) Nat. Med. , vol.2 , pp. 493
    • Thompson, W.D.1    Stirk, C.M.2    Smith, E.B.3
  • 3
    • 59149104284 scopus 로고    scopus 로고
    • Proteinases in cutaneous wound healing
    • M. Toriseva, and V.M. Kähäri Proteinases in cutaneous wound healing Cell. Mol. Life Sci. 66 2009 203 224
    • (2009) Cell. Mol. Life Sci. , vol.66 , pp. 203-224
    • Toriseva, M.1    Kähäri, V.M.2
  • 4
    • 77953685065 scopus 로고    scopus 로고
    • Cell-delivery therapeutics for liver regeneration
    • W. Zhang, and L. Tucker-Kellogg H. Yu Cell-delivery therapeutics for liver regeneration Adv. Drug Deliv. Rev. 62 2010 814 826
    • (2010) Adv. Drug Deliv. Rev. , vol.62 , pp. 814-826
    • Zhang, W.1    Tucker-Kellogg, L.2    Yu, H.3
  • 6
    • 0034927107 scopus 로고    scopus 로고
    • Plasmin and matrix metalloproteinases in vascular remodeling
    • H.R. Lijnen Plasmin and matrix metalloproteinases in vascular remodeling Thromb. Haemost. 86 2001 324 333 (Pubitemid 32663963)
    • (2001) Thrombosis and Haemostasis , vol.86 , Issue.1 , pp. 324-333
    • Lijnen, H.R.1
  • 7
    • 0033532205 scopus 로고    scopus 로고
    • Activation of matrix metalloproteinase-9 (MMP-9) via a converging plasmin/stromelysin-1 cascade enhances tumor cell invasion
    • N. Ramos-DeSimone, and E. Hahn-Dantona J.P. Quigley Activation of matrix metalloproteinase-9 (MMP-9) via a converging plasmin/stromelysin-1 cascade enhances tumor cell invasion J. Biol. Chem. 274 1999 13066 13076
    • (1999) J. Biol. Chem. , vol.274 , pp. 13066-13076
    • Ramos-Desimone, N.1    Hahn-Dantona, E.2    Quigley, J.P.3
  • 8
    • 49549089512 scopus 로고    scopus 로고
    • VEGF release by MMP-9 mediated heparan sulphate cleavage induces colorectal cancer angiogenesis
    • L.J. Hawinkels, and K. Zuidwijk C.F. Sier VEGF release by MMP-9 mediated heparan sulphate cleavage induces colorectal cancer angiogenesis Eur. J. Cancer 44 2008 1904 1913
    • (2008) Eur. J. Cancer , vol.44 , pp. 1904-1913
    • Hawinkels, L.J.1    Zuidwijk, K.2    Sier, C.F.3
  • 9
    • 67649752328 scopus 로고    scopus 로고
    • Plasmin-mediated proteolysis is required for hepatocyte growth factor activation during liver repair
    • K. Shanmukhappa, and U. Matte J.A. Bezerra Plasmin-mediated proteolysis is required for hepatocyte growth factor activation during liver repair J. Biol. Chem. 284 2009 12917 12923
    • (2009) J. Biol. Chem. , vol.284 , pp. 12917-12923
    • Shanmukhappa, K.1    Matte, U.2    Bezerra, J.A.3
  • 10
    • 0025215307 scopus 로고
    • Mechanism of activation of latent recombinant transforming growth factor β 1 by plasmin
    • R.M. Lyons, and L.E. Gentry H.L. Moses Mechanism of activation of latent recombinant transforming growth factor β 1 by plasmin J. Cell Biol. 110 1990 1361 1367
    • (1990) J. Cell Biol. , vol.110 , pp. 1361-1367
    • Lyons, R.M.1    Gentry, L.E.2    Moses, H.L.3
  • 11
    • 0041802737 scopus 로고    scopus 로고
    • Plasminogen activator/plasmin system: A major player in wound healing?
    • DOI 10.1046/j.1524-475X.2003.11402.x
    • W.Y. Li, and S.S. Chong T.L. Tuan Plasminogen activator/plasmin system: a major player in wound healing? Wound Repair Regen. 11 2003 239 247 (Pubitemid 36897519)
    • (2003) Wound Repair and Regeneration , vol.11 , Issue.4 , pp. 239-247
    • Li, W.-Y.1    Chong, S.S.N.2    Huang, E.Y.3    Tuan, T.-L.4
  • 12
    • 0025089051 scopus 로고
    • 2-macroglobulin, and antithrombin III in the pressure of heparin
    • DOI 10.1016/0049-3848(90)90406-3
    • P.K. Anonick, B. Wolf, and S.L. Gonias Regulation of plasmin, miniplasmin, and streptokinase-plasmin complex by α2-antiplasmin, α2-macroglobulin, and antithrombin III in the presence of heparin Thromb. Res. 59 1990 449 462 (Pubitemid 20330326)
    • (1990) Thrombosis Research , vol.59 , Issue.3 , pp. 449-462
    • Anonick, P.K.1    Wolf, B.B.2    Gonias, S.L.3
  • 13
    • 34250350056 scopus 로고    scopus 로고
    • Modeling of the role of a Bax-activation switch in the mitochondrial apoptosis decision
    • DOI 10.1529/biophysj.106.099606
    • C. Chen, and J. Cui P. Shen Modeling of the role of a Bax-activation switch in the mitochondrial apoptosis decision Biophys. J. 92 2007 4304 4315 (Pubitemid 46910545)
    • (2007) Biophysical Journal , vol.92 , Issue.12 , pp. 4304-4315
    • Chen, C.1    Cui, J.2    Lu, H.3    Wang, R.4    Zhang, S.5    Shen, P.6
  • 14
    • 44849128902 scopus 로고    scopus 로고
    • Two independent positive feedbacks and bistability in the Bcl-2 apoptotic switch
    • J. Cui, and C. Chen P. Shen Two independent positive feedbacks and bistability in the Bcl-2 apoptotic switch PLoS ONE 3 2008 e1469
    • (2008) PLoS ONE , vol.3 , pp. 1469
    • Cui, J.1    Chen, C.2    Shen, P.3
  • 16
    • 4344667310 scopus 로고    scopus 로고
    • The blood coagulation cascade
    • DOI 10.1097/01.moh.0000130308.37353.d4
    • M. Schenone, B.C. Furie, and B. Furie The blood coagulation cascade Curr. Opin. Hematol. 11 2004 272 277 (Pubitemid 39120956)
    • (2004) Current Opinion in Hematology , vol.11 , Issue.4 , pp. 272-277
    • Schenone, M.1    Furie, B.C.2    Furie, B.3
  • 17
    • 33645085024 scopus 로고    scopus 로고
    • New analysis technique for multistability detection
    • D. Angeli New analysis technique for multistability detection Syst. Biol. (Stevenage) 153 2006 61 69
    • (2006) Syst. Biol. (Stevenage) , vol.153 , pp. 61-69
    • Angeli, D.1
  • 18
    • 0033555859 scopus 로고    scopus 로고
    • Emergent properties of networks of biological signaling pathways
    • U.S. Bhalla, and R. Iyengar Emergent properties of networks of biological signaling pathways Science 283 1999 381 387
    • (1999) Science , vol.283 , pp. 381-387
    • Bhalla, U.S.1    Iyengar, R.2
  • 20
    • 0842288229 scopus 로고    scopus 로고
    • Signaling switches and bistability arising from multisite phosphorylation in protein kinase cascades
    • DOI 10.1083/jcb.200308060
    • N.I. Markevich, J.B. Hoek, and B.N. Kholodenko Signaling switches and bistability arising from multisite phosphorylation in protein kinase cascades J. Cell Biol. 164 2004 353 359 (Pubitemid 38174763)
    • (2004) Journal of Cell Biology , vol.164 , Issue.3 , pp. 353-359
    • Markevich, N.I.1    Hoek, J.B.2    Kholodenko, B.N.3
  • 21
    • 0035822634 scopus 로고    scopus 로고
    • Bistability in the JNK cascade
    • DOI 10.1016/S0960-9822(01)00330-X
    • C.P. Bagowski, and J.E. Ferrell Jr. Bistability in the JNK cascade Curr. Biol. 11 2001 1176 1182 (Pubitemid 32722570)
    • (2001) Current Biology , vol.11 , Issue.15 , pp. 1176-1182
    • Bagowski, C.P.1    Ferrell Jr., J.E.2
  • 23
    • 34347381069 scopus 로고    scopus 로고
    • Irreversible cell-cycle transitions are due to systems-level feedback
    • DOI 10.1038/ncb0707-724, PII NCB0707-724
    • B. Novak, and J.J. Tyson A. Csikasz-Nagy Irreversible cell-cycle transitions are due to systems-level feedback Nat. Cell Biol. 9 2007 724 728 (Pubitemid 47019454)
    • (2007) Nature Cell Biology , vol.9 , Issue.7 , pp. 724-728
    • Novak, B.1    Tyson, J.J.2    Gyorffy, B.3    Csikasz-Nagy, A.4
  • 24
    • 34547836607 scopus 로고    scopus 로고
    • Steady state and (bi-) stability evaluation of simple protease signalling networks
    • DOI 10.1016/j.biosystems.2007.01.003, PII S0303264707000184
    • T. Eissing, and S. Waldherr E. Bullinger Steady state and (bi-) stability evaluation of simple protease signalling networks Biosystems 90 2007 591 601 (Pubitemid 350026175)
    • (2007) BioSystems , vol.90 , Issue.3 , pp. 591-601
    • Eissing, T.1    Waldherr, S.2    Allgower, F.3    Scheurich, P.4    Bullinger, E.5
  • 25
    • 33947304756 scopus 로고    scopus 로고
    • Substrate Competition as a Source of Ultrasensitivity in the Inactivation of Wee1
    • DOI 10.1016/j.cell.2007.01.039, PII S0092867407002024
    • S.Y. Kim, and J.E. Ferrell Jr. Substrate competition as a source of ultrasensitivity in the inactivation of Wee1 Cell 128 2007 1133 1145 (Pubitemid 46437260)
    • (2007) Cell , vol.128 , Issue.6 , pp. 1133-1145
    • Kim, S.Y.1    Ferrell Jr., J.E.2
  • 26
    • 33947426526 scopus 로고    scopus 로고
    • The CASBAH: A searchable database of caspase substrates
    • DOI 10.1038/sj.cdd.4402103, PII 4402103
    • A.U. Lüthi, and S.J. Martin The CASBAH: a searchable database of caspase substrates Cell Death Differ. 14 2007 641 650 (Pubitemid 46444502)
    • (2007) Cell Death and Differentiation , vol.14 , Issue.4 , pp. 641-650
    • Luthi, A.U.1    Martin, S.J.2
  • 28
    • 35348866243 scopus 로고    scopus 로고
    • Robustness analysis identifies the plausible model of the Bcl-2 apoptotic switch
    • DOI 10.1016/j.febslet.2007.09.063, PII S0014579307010484
    • C. Chen, and J. Cui P. Shen Robustness analysis identifies the plausible model of the Bcl-2 apoptotic switch FEBS Lett. 581 2007 5143 5150 (Pubitemid 47576101)
    • (2007) FEBS Letters , vol.581 , Issue.26 , pp. 5143-5150
    • Chen, C.1    Cui, J.2    Zhang, W.3    Shen, P.4
  • 30
    • 0023153577 scopus 로고
    • Activation of plasminogen by single-chain urokinase or by two-chain urokinase: A demonstration that single-chain urokinase has a low catalytic activity (pro-urokinase)
    • R. Pannell, and V. Gurewich Activation of plasminogen by single-chain urokinase or by two-chain urokinase - a demonstration that single-chain urokinase has a low catalytic activity (pro-urokinase) Blood 69 1987 22 26 (Pubitemid 17007070)
    • (1987) Blood , vol.69 , Issue.1 , pp. 22-26
    • Pannell, R.1    Gurewich, V.2
  • 31
    • 0023199478 scopus 로고
    • Plasminogen activation by single-chain urokinase in functional isolation. Kinetic study
    • V. Ellis, M.F. Scully, and V.V. Kakkar Plasminogen activation by single-chain urokinase in functional isolation. A kinetic study J. Biol. Chem. 262 1987 14998 15003 (Pubitemid 17160171)
    • (1987) Journal of Biological Chemistry , vol.262 , Issue.31 , pp. 14998-15003
    • Ellis, V.1    Scully, M.F.2    Kakkar, V.V.3
  • 32
    • 0021082363 scopus 로고
    • The effects of fibrinogen and its cleavage products on the kinetics of plasminogen activation by urokinase and subsequent plasmin activity
    • M.A. Lucas, and D.L. Straight P.A. McKee The effects of fibrinogen and its cleavage products on the kinetics of plasminogen activation by urokinase and subsequent plasmin activity J. Biol. Chem. 258 1983 12171 12177 (Pubitemid 14230006)
    • (1983) Journal of Biological Chemistry , vol.258 , Issue.20 , pp. 12171-12177
    • Lucas, M.A.1    Straight, D.L.2    Fretto, L.J.3    McKee, P.A.4
  • 33
    • 0024368891 scopus 로고
    • The mechanism of plasminogen activation and fibrin dissolution by single chain urokinase-type plasminogen activator in a plasma milieu in vitro
    • H.R. Lijnen, and B. Van Hoef D. Collen The mechanism of plasminogen activation and fibrin dissolution by single chain urokinase-type plasminogen activator in a plasma milieu in vitro Blood 73 1989 1864 1872 (Pubitemid 19145118)
    • (1989) Blood , vol.73 , Issue.7 , pp. 1864-1872
    • Lijnen, H.R.1    Van Hoef, B.2    De Cock, F.3    Collen, D.4
  • 34
    • 84857114473 scopus 로고    scopus 로고
    • Mechanisms generating ultrasensitivity, bistability, and oscillations in signal transduction
    • S. Choi, Humana Press Totowa, NJ
    • N. Blüthgen, and S. Legewie B. Kholodenko Mechanisms generating ultrasensitivity, bistability, and oscillations in signal transduction S. Choi, Introduction to Systems Biology 2007 Humana Press Totowa, NJ 282 299
    • (2007) Introduction to Systems Biology , pp. 282-299
    • Blüthgen, N.1    Legewie, S.2    Kholodenko, B.3
  • 35
    • 0036532226 scopus 로고    scopus 로고
    • Self-perpetuating states in signal transduction: Positive feedback, double-negative feedback and bistability
    • DOI 10.1016/S0955-0674(02)00314-9
    • J.E. Ferrell Jr. Self-perpetuating states in signal transduction: positive feedback, double-negative feedback and bistability Curr. Opin. Cell Biol. 14 2002 140 148 (Pubitemid 34219501)
    • (2002) Current Opinion in Cell Biology , vol.14 , Issue.2 , pp. 140-148
    • Ferrell Jr., J.E.1
  • 36
    • 0019003787 scopus 로고
    • Rat liver phosphofructokinase: Kinetic activity under near-physiological conditions
    • G.D. Reinhart, and H.A. Lardy Rat liver phosphofructokinase: kinetic activity under near-physiological conditions Biochemistry 19 1980 1477 1484
    • (1980) Biochemistry , vol.19 , pp. 1477-1484
    • Reinhart, G.D.1    Lardy, H.A.2
  • 37
    • 77955296886 scopus 로고
    • Human plasminogen and plasmin
    • J.N. Abelson, M.I. Simon, Academic Press New York
    • K.C. Robbins, and L. Summaria Human plasminogen and plasmin J.N. Abelson, M.I. Simon, Methods in Enzymology 1970 Academic Press New York 184 199
    • (1970) Methods in Enzymology , pp. 184-199
    • Robbins, K.C.1    Summaria, L.2
  • 38
    • 0020045861 scopus 로고
    • Interaction of plasminogen activators and inhibitors with plasminogen and fibrin
    • H.R. Lijnen, and D. Collen Interaction of plasminogen activators and inhibitors with plasminogen and fibrin Semin. Thromb. Hemost. 8 1982 2 10 (Pubitemid 12148543)
    • (1982) Seminars in Thrombosis and Hemostasis , vol.8 , Issue.1 , pp. 2-10
    • Lijnen, H.R.1    Collen, D.2
  • 39
    • 0015351412 scopus 로고
    • Metabolism of plasminogen in healthy subjects: Effect of tranexamic acid
    • D. Collen, and G. Tytgat P. Wallén Metabolism of plasminogen in healthy subjects: effect of tranexamic acid J. Clin. Invest. 51 1972 1310 1318
    • (1972) J. Clin. Invest. , vol.51 , pp. 1310-1318
    • Collen, D.1    Tytgat, G.2    Wallén, P.3
  • 41
    • 0018750084 scopus 로고
    • The demonstration of urokinase antigen in whole blood
    • DOI 10.1016/0049-3848(79)90002-1
    • M. Shakespeare, and P. Wolf The demonstration of urokinase antigen in whole blood Thromb. Res. 14 1979 825 835 (Pubitemid 9209745)
    • (1979) Thrombosis Research , vol.14 , Issue.6 , pp. 825-835
    • Shakespeare, M.1    Wolf, P.2
  • 42
    • 0025255847 scopus 로고
    • The concentration of tissue plasminogen activator and urokinase in plasma and tissues of patients with ovarian and uterine tumors
    • DOI 10.1016/0049-3848(90)90207-S
    • K. Saito, and M. Nagashima A. Takada The concentration of tissue plasminogen activator and urokinase in plasma and tissues of patients with ovarian and uterine tumors Thromb. Res. 58 1990 355 366 (Pubitemid 20146928)
    • (1990) Thrombosis Research , vol.58 , Issue.4 , pp. 355-366
    • Saito, K.1    Nagashima, M.2    Iwata, M.3    Hamada, H.4    Sumiyoshi, K.5    Takada, Y.6    Takada, A.7
  • 43
    • 0023689428 scopus 로고
    • Increased plasma levels of urokinase-type plasminogen activator with endometrial and cervical cancer
    • H. Koelbl, and J.C. Kirchheimer B.R. Binder Increased plasma levels of urokinase-type plasminogen activator with endometrial and cervical cancer Obstet. Gynecol. 72 1988 252 256
    • (1988) Obstet. Gynecol. , vol.72 , pp. 252-256
    • Koelbl, H.1    Kirchheimer, J.C.2    Binder, B.R.3
  • 44
    • 0036199864 scopus 로고    scopus 로고
    • Selected parameters of fibrinolysis system in patients with dermatitis herpetiformis
    • A. Wankiewicz, and I. Iwan-Zietek Z. Gwieździński Selected parameters of fibrinolysis system in patients with dermatitis herpetiformis Med. Sci. Monit. 8 2002 CR189 CR192
    • (2002) Med. Sci. Monit. , vol.8
    • Wankiewicz, A.1    Iwan-Zietek, I.2    Gwieździński, Z.3
  • 45
    • 33646124974 scopus 로고    scopus 로고
    • Bistability in apoptosis: Roles of bax, bcl-2, and mitochondrial permeability transition pores
    • E.Z. Bagci, and Y. Vodovotz I. Bahar Bistability in apoptosis: roles of bax, bcl-2, and mitochondrial permeability transition pores Biophys. J. 90 2006 1546 1559
    • (2006) Biophys. J. , vol.90 , pp. 1546-1559
    • Bagci, E.Z.1    Vodovotz, Y.2    Bahar, I.3
  • 46
    • 33845537389 scopus 로고    scopus 로고
    • The history of the angiogenic switch concept
    • DOI 10.1038/sj.leu.2404402, PII 2404402
    • D. Ribatti, and B. Nico A. Vacca The history of the angiogenic switch concept Leukemia 21 2007 44 52 (Pubitemid 44921833)
    • (2007) Leukemia , vol.21 , Issue.1 , pp. 44-52
    • Ribatti, D.1    Nico, B.2    Crivellato, E.3    Roccaro, A.M.4    Vacca, A.5
  • 48
  • 51
    • 0025810460 scopus 로고
    • Half-life of single-chain urokinase-type plasminogen activator (scu-PA) and two-chain urokinase-type plasminogen activator (tcu-PA) in patients with acute myocardial infarction
    • M. Köhler, and S. Sen K. Hollemeyer Half-life of single-chain urokinase-type plasminogen activator (scu-PA) and two-chain urokinase-type plasminogen activator (tcu-PA) in patients with acute myocardial infarction Thromb. Res. 62 1991 75 81
    • (1991) Thromb. Res. , vol.62 , pp. 75-81
    • Köhler, M.1    Sen, S.2    Hollemeyer, K.3
  • 52
    • 33749370199 scopus 로고    scopus 로고
    • Mathematical modeling identifies inhibitors of apoptosis as mediators of positive feedback and bistability
    • S. Legewie, N. Blüthgen, and H. Herzel Mathematical modeling identifies inhibitors of apoptosis as mediators of positive feedback and bistability PLOS Comput. Biol. 2 2006 e120
    • (2006) PLOS Comput. Biol. , vol.2 , pp. 120
    • Legewie, S.1    Blüthgen, N.2    Herzel, H.3


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