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Volumn 18, Issue 5, 2011, Pages 379-392

Characterization of STAT6 target genes in human B cells and lung epithelial cells

Author keywords

ChIP Seq; IL 4; STAT6; TSS Seq

Indexed keywords

INTERLEUKIN 4; RNA POLYMERASE II; STAT6 PROTEIN; TRANSCRIPTION FACTOR;

EID: 80054700512     PISSN: 13402838     EISSN: 17561663     Source Type: Journal    
DOI: 10.1093/dnares/dsr025     Document Type: Article
Times cited : (20)

References (53)
  • 1
    • 0029876629 scopus 로고    scopus 로고
    • Stat6 is required for mediating responses to IL-4 and for the development of Th2 cells
    • DOI 10.1016/S1074-7613(00)80439-2
    • Kaplan, M.H., Schindler, U., Smiley, S.T. and Grusby, M.J. 1996, Stat6 is required for mediating responses to IL-4 and for development of Th2 cells, Immunity, 4, 313-19. (Pubitemid 26132509)
    • (1996) Immunity , vol.4 , Issue.3 , pp. 313-319
    • Kaplan, M.H.1    Schindler, U.2    Smiley, S.T.3    Grusby, M.J.4
  • 2
    • 0029005095 scopus 로고
    • Inhibition of IL-4 receptor up-regulation on B cells by antisense oligodeoxynucleotide suppresses IL-4-induced human IgE production
    • Ikizawa, K., Kajiwara, K., Koshio, T., Matsuura, N. and Yanagihara, Y. 1995, Inhibition of IL-4 receptor up-regulation on B cells by antisense oligodeoxynucleotide suppresses IL-4-induced human IgE production, Clin. Exp. Immunol., 100, 383-89.
    • (1995) Clin. Exp. Immunol. , vol.100 , pp. 383-389
    • Ikizawa, K.1    Kajiwara, K.2    Koshio, T.3    Matsuura, N.4    Yanagihara, Y.5
  • 3
    • 0034881918 scopus 로고    scopus 로고
    • New insights into the role of cytokines in asthma
    • Renauld, J.C. 2001, New insights into the role of cytokines in asthma, J. Clin. Pathol., 54, 577-89.
    • (2001) J. Clin. Pathol. , vol.54 , pp. 577-589
    • Renauld, J.C.1
  • 4
    • 0034142166 scopus 로고    scopus 로고
    • Atopy and asthma: Genetic variants of IL-4 and IL-13 signalling
    • DOI 10.1016/S0167-5699(99)01492-9, PII S0167569999014929
    • Shirakawa, I., Deichmann, K.A., Izuhara, I., Mao, I., Adra, C.N. and Hopkin, J.M. 2000, Atopy and asthma: genetic variants of IL-4 and IL-13 signalling, Immunol. Today, 21, 60-4. (Pubitemid 30069614)
    • (2000) Immunology Today , vol.21 , Issue.2 , pp. 60-64
    • Shirakawa, T.1    Deichmann, K.A.2    Izuhara, K.3    Mao, X.-Q.4    Adra, C.N.5    Hopkin, J.M.6
  • 5
    • 53849139093 scopus 로고    scopus 로고
    • Interleukin-4, interleukin-13, signal transducer and activator of transcription factor 6, and allergic asthma
    • Kuperman, D.A. and Schleimer, R.P. 2008, Interleukin-4, interleukin-13, signal transducer and activator of transcription factor 6, and allergic asthma. Curr. Mol. Med., 8, 384-92.
    • (2008) Curr. Mol. Med. , vol.8 , pp. 384-392
    • Kuperman, D.A.1    Schleimer, R.P.2
  • 6
    • 78649516124 scopus 로고    scopus 로고
    • Functions of T cells in asthma: More than just T(H)2 cells
    • Lloyd, C.M. and Hessel, E.M. 2010, Functions of T cells in asthma: more than just T(H)2 cells, Nat. Rev., 10, 838-48.
    • (2010) Nat. Rev. , vol.10 , pp. 838-848
    • Lloyd, C.M.1    Hessel, E.M.2
  • 7
    • 40049092917 scopus 로고    scopus 로고
    • Treatment strategies for allergy and asthma
    • DOI 10.1038/nri2262, PII NRI2262
    • Holgate, S.T. and Polosa, R. 2008, Treatment strategies for allergy and asthma, Nat. Rev., 8, 218-30. (Pubitemid 351323290)
    • (2008) Nature Reviews Immunology , vol.8 , Issue.3 , pp. 218-230
    • Holgate, S.T.1    Polosa, R.2
  • 8
  • 9
    • 0035313367 scopus 로고    scopus 로고
    • STAT6 mediates eotaxin-1 expression in IL-4 or TNF-α-induced fibroblasts
    • Hoeck, J. and Woisetschlager, M. 2001, STAT6 mediates eotaxin-1 expression in IL-4 or TNF-alpha-induced fibroblasts, J. Immunol., 166, 4507-15. (Pubitemid 32233735)
    • (2001) Journal of Immunology , vol.166 , Issue.7 , pp. 4507-4515
    • Hoeck, J.1    Woisetschlager, M.2
  • 10
    • 0032756132 scopus 로고    scopus 로고
    • Activation of eotaxin gene transcription by NF-kappa B and STAT6 in human airway epithelial cells
    • Matsukura, S., Stellato, C., Plitt, J.R., et al. 1999, Activation of eotaxin gene transcription by NF-kappa B and STAT6 in human airway epithelial cells, J. Immunol., 163, 6876-83.
    • (1999) J. Immunol. , vol.163 , pp. 6876-6883
    • Matsukura, S.1    Stellato, C.2    Plitt, J.R.3
  • 11
    • 0033563258 scopus 로고    scopus 로고
    • IL-4 induces mucin gene expression and goblet cell metaplasia in vitro and in vivo
    • Dabbagh, K., Takeyama, K., Lee, H.M., Ueki, I.F., Lausier, J.A. and Nadel, J.A. 1999, IL-4 induces mucin gene expression and goblet cell metaplasia in vitro and in vivo, J. Immunol., 162, 6233-7. (Pubitemid 29314987)
    • (1999) Journal of Immunology , vol.162 , Issue.10 , pp. 6233-6237
    • Dabbagh, K.1    Takeyama, K.2    Lee, H.-M.3    Ueki, I.F.4    Lausier, J.A.5    Nadel, J.A.6
  • 12
    • 0033564686 scopus 로고    scopus 로고
    • Differences between IL-4- and IL-4 receptor α-deficient mice in chronic Leishmaniasis reveal a protective role for IL-13 receptor signaling
    • Mohrs, M., Ledermann, B., Kohler, G., Dorfmuller, A., Gessner, A. and Brombacher, F. 1999, Differences between IL-4-and IL-4 receptor alpha-deficient mice in chronic leishmaniasis reveal a protective role for IL-13 receptor signaling, J. Immunol., 162, 7302-8. (Pubitemid 29277704)
    • (1999) Journal of Immunology , vol.162 , Issue.12 , pp. 7302-7308
    • Mohrs, M.1    Ledermann, B.2    Kohler, G.3    Dorfmuller, A.4    Gessner, A.5    Brombacher, F.6
  • 14
    • 0034832208 scopus 로고    scopus 로고
    • Biological and clinical significance of the JAK-STAT pathway; lessons from knockout mice
    • Igaz, P., Toth, S. and Falus, A. 2001, Biological and clinical significance of the JAK-STAT pathway; lessons from knockout mice, Inflamm. Res., 50, 435-41. (Pubitemid 32889442)
    • (2001) Inflammation Research , vol.50 , Issue.9 , pp. 435-441
    • Igaz, P.1    Toth, S.2    Falus, A.3
  • 15
    • 33744546660 scopus 로고    scopus 로고
    • Signaling mechanisms, interaction partners, and target genes of STAT6
    • DOI 10.1016/j.cytogfr.2006.01.004, PII S1359610106000025
    • Hebenstreit, D., Wirnsberger, G., Horejs-Hoeck, J. and Duschl, A. 2006, Signaling mechanisms, interaction partners, and target genes of STAT6, Cytok. Growth Factor Rev., 17, 173-88. (Pubitemid 43816893)
    • (2006) Cytokine and Growth Factor Reviews , vol.17 , Issue.3 , pp. 173-188
    • Hebenstreit, D.1    Wirnsberger, G.2    Horejs-Hoeck, J.3    Duschl, A.4
  • 16
    • 0032535293 scopus 로고    scopus 로고
    • Stat6 inhibits human interleukin-4 promoter activity in T cells
    • Georas, S.N., Cumberland, J.E., Burke, T.F., Chen, R., Schindler, U. and Casolaro, V. 1998, Stat6 inhibits human interleukin-4 promoter activity in T cells, Blood, 92, 4529-38. (Pubitemid 29005853)
    • (1998) Blood , vol.92 , Issue.12 , pp. 4529-4538
    • Georas, S.N.1    Cumberland, J.E.2    Burke, T.F.3    Chen, R.4    Schindler, U.5    Casolaro, V.6
  • 17
    • 0037442218 scopus 로고    scopus 로고
    • The Th2 cell cytokines IL-4 and IL-13 regulate found in inflammatory zone 1/resistin-like molecule α gene expression by a STAT6 and CCAAT/enhancer-binding protein-dependent mechanism
    • Stutz, A.M., Pickart, L.A., Trifilieff, A., Baumruker, T., Prieschl-Strassmayr, E. and Woisetschlager, M. 2003, The Th2 cell cytokines IL-4 and IL-13 regulate found in inflammatory zone 1/resistin-like molecule alpha gene expression by a STAT6 and CCAAT/enhancerbinding protein-dependent mechanism, J. Immunol., 170, 1789-96. (Pubitemid 36197394)
    • (2003) Journal of Immunology , vol.170 , Issue.4 , pp. 1789-1796
    • Stutz, A.M.1    Pickart, L.A.2    Trifilieff, A.3    Baumruker, T.4    Prieschl-Strassmayr, E.5
  • 19
    • 33846523494 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling-1 is an IL-4-inducible gene in macrophages and feedback inhibits IL-4 signaling
    • DOI 10.1038/sj.gene.6364352, PII 6364352
    • Dickensheets, H., Vazquez, N., Sheikh, F., et al. 2007, Suppressor of cytokine signaling-1 is an IL-4-inducible gene in macrophages and feedback inhibits IL-4 signaling, Genes Immun., 8, 21-7. (Pubitemid 46158099)
    • (2007) Genes and Immunity , vol.8 , Issue.1 , pp. 21-27
    • Dickensheets, H.1    Vazquez, N.2    Sheikh, F.3    Gingras, S.4    Murray, P.J.5    Ryan, J.J.6    Donnelly, R.P.7
  • 22
    • 77953881949 scopus 로고    scopus 로고
    • Genome-wide profiling of interleukin-4 and STAT6 transcription factor regulation of human Th2 cell programming
    • Elo, L.L., Jarvenpaa, H., Tuomela, S., et al. 2010, Genome-wide profiling of interleukin-4 and STAT6 transcription factor regulation of human Th2 cell programming, Immunity, 32, 852-62.
    • (2010) Immunity , vol.32 , pp. 852-862
    • Elo, L.L.1    Jarvenpaa, H.2    Tuomela, S.3
  • 23
    • 34250159524 scopus 로고    scopus 로고
    • Genome-wide mapping of in vivo protein-DNA interactions
    • DOI 10.1126/science.1141319
    • Johnson, D.S., Mortazavi, A., Myers, R.M. and Wold, B. 2007, Genome-wide mapping of in vivo protein-DNA interactions, Science, 316, 1497-502. (Pubitemid 46906620)
    • (2007) Science , vol.316 , Issue.5830 , pp. 1497-1502
    • Johnson, D.S.1    Mortazavi, A.2    Myers, R.M.3    Wold, B.4
  • 26
    • 57149096220 scopus 로고    scopus 로고
    • Genome-wide relationship between histone H3 lysine 4 mono-and tri-methylation and transcription factor binding
    • Robertson, A.G., Bilenky, M., Tam, A., et al. 2008, Genome-wide relationship between histone H3 lysine 4 mono-and tri-methylation and transcription factor binding, Genome Res., 18, 1906-17.
    • (2008) Genome Res. , vol.18 , pp. 1906-1917
    • Robertson, A.G.1    Bilenky, M.2    Tam, A.3
  • 28
    • 65549105550 scopus 로고    scopus 로고
    • Massive transcriptional start site analysis of human genes in hypoxia cells
    • Tsuchihara, K., Suzuki, Y., Wakaguri, H., et al. 2009, Massive transcriptional start site analysis of human genes in hypoxia cells, Nucleic Acids Res., 37, 2249-63.
    • (2009) Nucleic Acids Res. , vol.37 , pp. 2249-2263
    • Tsuchihara, K.1    Suzuki, Y.2    Wakaguri, H.3
  • 29
    • 77955953730 scopus 로고    scopus 로고
    • Characterization of transcription start sites of putative non-coding RNAs by multifaceted use of massively paralleled sequencer
    • Sathira, N., Yamashita, R., Tanimoto, K., et al. 2010, Characterization of transcription start sites of putative non-coding RNAs by multifaceted use of massively paralleled sequencer, DNA Res., 17, 169-83.
    • (2010) DNA Res. , vol.17 , pp. 169-183
    • Sathira, N.1    Yamashita, R.2    Tanimoto, K.3
  • 30
    • 0037977720 scopus 로고    scopus 로고
    • Construction of a fulllength enriched and a 5'-end enriched cDNA library using the oligo-capping method
    • Suzuki, Y. and Sugano, S. 2003, Construction of a fulllength enriched and a 5'-end enriched cDNA library using the oligo-capping method, Methods Mol. Biol., 221, 73-91.
    • (2003) Methods Mol. Biol. , vol.221 , pp. 73-91
    • Suzuki, Y.1    Sugano, S.2
  • 31
    • 24644519490 scopus 로고    scopus 로고
    • The transcriptional landscape of the mammalian genome
    • Carninci, P., Kasukawa, T., Katayama, S., et al. 2005, The transcriptional landscape of the mammalian genome, Science, 309, 1559-63.
    • (2005) Science , vol.309 , pp. 1559-1563
    • Carninci, P.1    Kasukawa, T.2    Katayama, S.3
  • 34
    • 67849122320 scopus 로고    scopus 로고
    • MEME SUITE: Tools for motif discovery and searching
    • Bailey, T.L., Boden, M., Buske, F.A., et al. 2009, MEME SUITE: tools for motif discovery and searching, Nucleic Acids Res., 37, W202-8.
    • (2009) Nucleic Acids Res. , vol.37
    • Bailey, T.L.1    Boden, M.2    Buske, F.A.3
  • 35
    • 0029001660 scopus 로고
    • Components of a Stat recognition code: Evidence for two layers of molecular selectivity
    • Schindler, U., Wu, P., Rothe, M., Brasseur, M. and McKnight, S.L. 1995, Components of a Stat recognition code: evidence for two layers of molecular selectivity, Immunity, 2, 689-97.
    • (1995) Immunity , vol.2 , pp. 689-697
    • Schindler, U.1    Wu, P.2    Rothe, M.3    Brasseur, M.4    McKnight, S.L.5
  • 36
    • 0035794217 scopus 로고    scopus 로고
    • DNA binding specificity of different STAT proteins. Comparison of in vitro specificity with natural target sites
    • Ehret, G.B., Reichenbach, P., Schindler, U., et al. 2001, DNA binding specificity of different STAT proteins. Comparison of in vitro specificity with natural target sites, J. Biol. Chem., 276, 6675-88.
    • (2001) J. Biol. Chem. , vol.276 , pp. 6675-6688
    • Ehret, G.B.1    Reichenbach, P.2    Schindler, U.3
  • 37
    • 0022370476 scopus 로고
    • The B cell surface molecule B1 is functionally linked with B cell activation and differentiation
    • Tedder, T.F., Boyd, A.W., Freedman, A.S., Nadler, L.M. and Schlossman, S.F. 1985, The B cell surface molecule B1 is functionally linked with B cell activation and differentiation, J. Immunol., 135, 973-9. (Pubitemid 16242785)
    • (1985) Journal of Immunology , vol.135 , Issue.2 , pp. 973-979
    • Tedder, T.F.1    Boyd, A.W.2    Freedman, A.S.3
  • 38
    • 0022510242 scopus 로고
    • Antibodies reactive with the B1 molecule inhibit cell cycle progression but not activation of human B lymphocytes
    • Tedder, T.F., Forsgren, A., Boyd, A.W., Nadler, L.M. and Schlossman, S.F. 1986, Antibodies reactive with the B1 molecule inhibit cell cycle progression but not activation of human B lymphocytes, Eur. J. Immunol., 16, 881-7. (Pubitemid 16053982)
    • (1986) European Journal of Immunology , vol.16 , Issue.8 , pp. 881-887
    • Tedder, T.F.1    Forsgren, A.2    Boyd, A.W.3
  • 39
    • 0642312825 scopus 로고    scopus 로고
    • Rituximab (monoclonal anti-CD20 antibody): Mechanisms of action and resistance
    • Smith, M.R. 2003, Rituximab (monoclonal anti-CD20 antibody): mechanisms of action and resistance, Oncogene, 22, 7359-68.
    • (2003) Oncogene , vol.22 , pp. 7359-7368
    • Smith, M.R.1
  • 40
    • 34548221347 scopus 로고    scopus 로고
    • Mechanisms of killing by anti-CD20 monoclonal antibodies
    • DOI 10.1016/j.molimm.2007.06.151, PII S0161589007002623, XIth European meeting on Complement in Human Disease
    • Glennie, M.J., French, R.R., Cragg, M.S. and Taylor, R.P. 2007, Mechanisms of killing by anti-CD20 monoclonal antibodies, Mol. Immunol., 44, 3823-37. (Pubitemid 47332625)
    • (2007) Molecular Immunology , vol.44 , Issue.16 , pp. 3823-3837
    • Glennie, M.J.1    French, R.R.2    Cragg, M.S.3    Taylor, R.P.4
  • 42
    • 33644694711 scopus 로고    scopus 로고
    • The multiple function of Grb2 associated binder (Gab) adaptor/scaffolding protein in immune cell signaling
    • DOI 10.1016/j.imlet.2005.11.017, PII S0165247805003627, Signal and Signaling Processing in the Immune System
    • Sarmay, G., Angyal, A., Kertesz, A., Maus, M. and Medgyesi, D. 2006, The multiple function of Grb2 associated binder (Gab) adaptor/scaffolding protein in immune cell signaling, Immunol. Lett., 104, 76-82. (Pubitemid 43330712)
    • (2006) Immunology Letters , vol.104 , Issue.1-2 , pp. 76-82
    • Sarmay, G.1    Angyal, A.2    Kertesz, A.3    Maus, M.4    Medgyesi, D.5
  • 45
    • 38549094621 scopus 로고    scopus 로고
    • DBTSS: Database of transcription start sites, progress report 2008
    • DOI 10.1093/nar/gkm901
    • Wakaguri, H., Yamashita, R., Suzuki, Y., Sugano, S. and Nakai, K. 2008, DBTSS: database of transcription start sites, progress report 2008. Nucleic Acids Res., 36, D97-101. (Pubitemid 351149703)
    • (2008) Nucleic Acids Research , vol.36 , Issue.SUPPL. 1
    • Wakaguri, H.1    Yamashita, R.2    Suzuki, Y.3    Sugano, S.4    Nakai, K.5
  • 46
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin Modifications and Their Function
    • DOI 10.1016/j.cell.2007.02.005, PII S0092867407001845
    • Kouzarides, T. 2007, Chromatin modifications and their function, Cell, 128, 693-705. (Pubitemid 46273577)
    • (2007) Cell , vol.128 , Issue.4 , pp. 693-705
    • Kouzarides, T.1
  • 47
    • 0029960055 scopus 로고    scopus 로고
    • TRANSFAC: A database on transcription factors and their DNA binding sites
    • DOI 10.1093/nar/24.1.238
    • Wingender, E., Dietze, P., Karas, H. and Knuppel, R. 1996, TRANSFAC: a database on transcription factors and their DNA binding sites, Nucleic Acids Res., 24, 238-41. (Pubitemid 26085775)
    • (1996) Nucleic Acids Research , vol.24 , Issue.1 , pp. 238-241
    • Wingender, E.1    Dietze, P.2    Karas, H.3    Knuppel, R.4
  • 49
    • 33745809637 scopus 로고    scopus 로고
    • Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF
    • DOI 10.1038/nature04802, PII NATURE04802
    • Li, H., Ilin, S., Wang, W., et al. 2006, Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF, Nature, 442, 91-5. (Pubitemid 44064215)
    • (2006) Nature , vol.442 , Issue.7098 , pp. 91-95
    • Li, H.1    Ilin, S.2    Wang, W.3    Duncan, E.M.4    Wysocka, J.5    Allis, C.D.6    Patel, D.J.7
  • 50
    • 33749035033 scopus 로고    scopus 로고
    • CCR6 and CCL20: Partners in intestinal immunity and lymphorganogenesis
    • DOI 10.1196/annals.1326.036, Inflammatory Bowel Disease: Genetics, Barrier Function, Immunologic Mechanisms, and Microbial Pathways
    • Williams, I.R. 2006, CCR6 and CCL20: partners in intestinal immunity and lymphorganogenesis, Ann. N. Y. Acad. Sci., 1072, 52-61. (Pubitemid 44448443)
    • (2006) Annals of the New York Academy of Sciences , vol.1072 , pp. 52-61
    • Williams, I.R.1
  • 51
    • 1542328956 scopus 로고    scopus 로고
    • A mitochondrial protein, Bit1, mediates apoptosis regulated by integrins and Groucho/TLE corepressors
    • DOI 10.1016/S0092-8674(04)00204-1, PII S0092867404002041
    • Jan, Y., Matter, M., Pai, J.T., et al. 2004, A mitochondrial protein, Bit1, mediates apoptosis regulated by integrins and Groucho/TLE corepressors, Cell, 116, 751-62. (Pubitemid 38326732)
    • (2004) Cell , vol.116 , Issue.5 , pp. 751-762
    • Jan, Y.1    Matter, M.2    Pai, J.-T.3    Chen, Y.-L.4    Pilch, J.5    Komatsu, M.6    Ong, E.7    Fukuda, M.8    Ruoslahti, E.9
  • 53
    • 0025753904 scopus 로고
    • Molecular cloning of cDNA and a chromosomal gene encoding GPEL-BP, a nuclear protein which binds to granulocyte colony-stimulating factor promoter element 1
    • Nishizawa, M., Wakabayashi-Ito, N. and Nagata, S. 1991, Molecular cloning of cDNA and a chromosomal gene encoding GPEL-BP, a nuclear protein which binds to granulocyte colony-stimulating factor promoter element 1, FEBS Lett., 282, 95-7.
    • (1991) FEBS Lett. , vol.282 , pp. 95-7
    • Nishizawa, M.1    Wakabayashi-Ito, N.2    Nagata, S.3


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