Group X secreted phospholipase A 2 proenzyme is matured by a furin-like proprotein convertase and releases arachidonic acid inside of human HEK293 cells

Journal of Biological Chemistry

Volumn 286, Issue 42, 2011, Pages 36509-36521

  Jemel, Ikram ^a   Ii, Hiromi ^b   Oslund, Rob C ^b   Payré, Christine ^a   Dabert Gay, Anne Sophie ^a   Douguet, Dominique ^a   Chargui, Khaoula ^a   Scarzello, Sabine ^a   Gelb, Michael H ^b   Lambeau, Gérard ^a  

^a INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONIC ACIDS; CONVERTASES; ENZYMATIC ACTIVITIES; HEK293 CELLS; HYDROLYZING ACTIVITY; PHOSPHATIDYLCHOLINE; PHOSPHOLIPASE A; PHOSPHOLIPASES; PROPEPTIDES; PROTEASE INHIBITOR; TRANSFECTED CELLS;

AMINO ACIDS; ENZYME ACTIVITY; ENZYME INHIBITION; MAMMALS; PLANTS (BOTANY); UNSATURATED FATTY ACIDS;

CELLS;

ARACHIDONIC ACID; FURIN LIKE PROPROTEIN CONVERTASE; GROUP X SECRETED PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 INHIBITOR; PROTEINASE INHIBITOR; SECRETORY PHOSPHOLIPASE A2; SERINE PROTEINASE; UNCLASSIFIED DRUG;

ARTICLE; CELL SECRETION; CELL STRAIN HEK293; CELL TRANSPORT; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME METABOLISM; HUMAN; HUMAN CELL; MATURATION; PRIORITY JOURNAL;

AMINO ACID MOTIFS; ANIMALS; ARACHIDONIC ACID; ENZYME PRECURSORS; GROUP X PHOSPHOLIPASES A2; HEK293 CELLS; HUMANS; MICE; MUTATION; PROPROTEIN CONVERTASES; PROTEASE INHIBITORS;

MAMMALIA;

EID: 80054698604     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.268540     Document Type: Article

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