Polynucleotide kinase and aprataxin-like forkhead-associated protein (PALF) acts as both a single-stranded DNA endonuclease and a single-stranded DNA 3′ exonuclease and can participate in DNA end joining in a biochemical system

Journal of Biological Chemistry

Volumn 286, Issue 42, 2011, Pages 36368-36377

  Li, Sicong ^a   Kanno, Shin Ichiro ^b   Watanabe, Reiko ^b   Ogiwara, Hideaki ^c   Kohno, Takashi ^c   Watanabe, Go ^a   Yasui, Akira ^b   Lieber, Michael R ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b TOHOKU UNIVERSITY   (Japan)

^c NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

APRATAXIN; ARTEMIS; BIOCHEMICAL SYSTEMS; CATALYTIC SUBUNITS; CHINESE HAMSTERS; DNA HAIRPIN; DNA LIGASES; DNA-DEPENDENT PROTEIN KINASE; ENDONUCLEASE ACTIVITIES; ENDONUCLEASES; EXONUCLEASE; EXONUCLEASE ACTIVITY; FORKHEAD-ASSOCIATED DOMAIN; IN-VIVO; JOINING PROCESS; KEY COMPONENT; NUCLEASE ACTIVITY; POLYNUCLEOTIDES; SINGLE-STRANDED DNA;

BIOCHEMISTRY; ENZYMES; JOINING; NUCLEOTIDES; PROTEINS;

DNA;

DEOXYRIBONUCLEASE; DNA LIGASE IV; DOUBLE STRANDED DNA; EXODEOXYRIBONUCLEASE; KU ANTIGEN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; POLYNUCLEOTIDE KINASE AND APRATAXIN LIKE FORKHEAD ASSOCIATED PROTEIN; SINGLE STRANDED DNA; UNCLASSIFIED DRUG; XRCC4 PROTEIN;

ARTICLE; DNA HAIRPIN; DNA STRUCTURE; ENZYME ACTIVITY; ENZYME REGULATION; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; IN VIVO STUDY; NONHOMOLOGOUS DNA END JOINING; NUCLEIC ACID STRUCTURE; PRIORITY JOURNAL; PROTEIN FUNCTION;

ANIMALS; CELL LINE; CRICETINAE; CRICETULUS; DNA HELICASES; DNA REPAIR; DNA, SINGLE-STRANDED; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; DNA-BINDING PROTEINS; EXONUCLEASES; HUMANS;

CRICETULUS GRISEUS;

EID: 80054683238     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.287797     Document Type: Article

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