Restoration of hepatic glycogen deposition reduces hyperglycaemia, hyperphagia and gluconeogenic enzymes in a streptozotocin-induced model of diabetes in rats

Diabetologia

Volumn 54, Issue 10, 2011, Pages 2639-2648

  Ros, S ^a,b,c,d   Garcia Rocha M ^a,b   Calbo J ^a,b   Guinovart, J J ^a,b,c  

^a INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c UNIVERSITY OF BARCELONA   (Spain)

^d IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

Diabetes; Food intake; Gluconeogenesis; Glucose homoeostasis; Glycogen; Hyperglycaemia; Liver; Liver glycogen synthase; Metabolism

Indexed keywords

BETA GALACTOSIDASE; FRUCTOSE BISPHOSPHATASE; GLUCOKINASE; GLUCOSE; GLUCOSE 6 PHOSPHATE; GLUCOSE TRANSPORTER 2; GLYCOGEN SYNTHASE; INSULIN; LACTIC ACID; LEPTIN; MESSENGER RNA; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PHOSPHOPROTEIN PHOSPHATASE 1; PYRUVATE CARBOXYLASE; TRIACYLGLYCEROL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL CULTURE; CELL ISOLATION; CONTROLLED STUDY; DIABETES MELLITUS; ENZYME ACTIVITY; FOOD INTAKE; GENE EXPRESSION; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; GLYCOGEN LIVER LEVEL; GLYCOGEN METABOLISM; HYPERGLYCEMIA; HYPERPHAGIA; IMMUNOREACTIVITY; LIVER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STREPTOZOCIN DIABETES;

ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; EATING; FRUCTOSE-BISPHOSPHATASE; GLUCONEOGENESIS; GLUCOSE-6-PHOSPHATASE; GLYCOGEN SYNTHASE; HEPATOCYTES; HYPERGLYCEMIA; IMMUNOBLOTTING; INSULIN; LIVER; LIVER GLYCOGEN; MALE; PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP); RATS; RATS, WISTAR;

EID: 80054121137     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-011-2238-x     Document Type: Article

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