Impulsivity and Parkinson's disease: More than just disinhibition

Journal of the Neurological Sciences

Volumn 310, Issue 1-2, 2011, Pages 202-207

  Antonelli, Francesca ^a,b   Ray, Nicola ^a,b   Strafella, Antonio P ^a,b  

^a TORONTO WESTERN HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Brain imaging; Dopamine; Impulse control disorders; Impulsivity; Parkinson's disease; Subthalamic nucleus

Indexed keywords

ARTIFICIAL NEURAL NETWORK; COGNITIVE DEFECT; DECISION MAKING; DISEASE PREDISPOSITION; HIGH RISK BEHAVIOR; HUMAN; IMPULSIVENESS; LEARNING; LIMBIC CORTEX; ORBITAL CORTEX; PARKINSON DISEASE; PATHOLOGICAL GAMBLING; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW; REWARD; SUBTHALAMIC NUCLEUS; TIME PERCEPTION; UNCERTAINTY;

EID: 80054112327     PISSN: 0022510X     EISSN: 18785883     Source Type: Journal    
DOI: 10.1016/j.jns.2011.06.006     Document Type: Article

References (94)

1. A. Bechara, H. Damasio, and A.R. Damasio Emotion, decision making and the orbitofrontal cortex Cereb Cortex 3 2000 295 307 (Pubitemid 30159296)
2. K. Harnishfeger The development of cognitive inhibition: theories, definition, and research evidence F. Dempster, C. Brainerd, Interference and inhibition in cognition. San Diego 1995 175 204
3. A.R. Aron The neural basis of inhibition in cognitive control Neuroscientist 3 2007 214 228 (Pubitemid 46801761)
4. A. Bechara Decision making, impulse control and loss of willpower to resist drugs: a neurocognitive perspective Nat Neurosci 8 2005 1458 1463 (Pubitemid 41573656)
5. M.M. Sweitzer, P.A. Allen, and K.P. Kaut Relation of individual differences in impulsivity to nonclinical emotional decision making J Int Neuropsychol Soc 14 2008 878 882
6. T.A. Hare, C.F. Camerer, and A. Rangel Self-control in decision-making involves modulation of the vmPFC valuation system Science 324 2009 646 648
7. A. Verdejo-García, and A. Bechara A somatic marker theory o addiction Neuropharmacology 56 2009 48 62
8. A.L. Krain, A.M. Wilson, R. Arbuckle, F.X. Castellanos, and M.P. Milham Distinct neural mechanisms of risk and ambiguity: a meta-analysis of decision-making Neuroimage 32 2006 477 484
9. J. Pagonabarraga, C. Garcia-Sanchez, G. Llebaria, B. Pascual-Sedano, A. Gironell, and J. Kulisevsky Controlled study of decsion-making and cognitive impairment in Parkinson's disease Mov Disord 22 2007 1430 1435 (Pubitemid 47280628)
10. M. Kobayakawa, S. Koyama, M. Mimura, and M. Kawamura Decision making in Parkinson's disease: analysis of behavioral and physiological patterns in the Iowa gambling task Mov Disord 23 2008 547 552
11. A. Bechara Risky business: emotion, decision-making, and addiction J Gambl Stud 19 2003 23 51 (Pubitemid 39012874)
12. I.H. Franken, J.W. van Strien, I. Nijs, and P. Muris Impulsivity is associated with behavioral decision-making deficits Psychiatry Res 158 2008 155 163
13. M. Brand, K. Labudda, and E. Kalbe Decision-making impairments in patients with Parkinson's disease Behav Neurol 15 2004 77 85 (Pubitemid 40202502)
14. M. Brand, K. Labudda, and H.J. Markowitsch Neuropsychological correlates of decision-making in ambiguous and risky situa tions Neural Netw 19 2006 1266 1276 (Pubitemid 44466330)
15. M. Brand, E.C. Recknor, F. Grabenhorst, and A. Bechara Decisions under ambiguity and decisions under risk: correlations with executive functions and comparisons of two different gambling tasks with implicit and explicit rules J Clin Exp Neuropsychol 29 2007 86 99 (Pubitemid 44950986)
16. G. Robert, D. Drapier, M. Verin, B. Millet, J.P. Azulay, and O. Blin Cognitive impulsivity in Parkinson's disease patients: assessment and pathophysiology Mov Disord 24 2009 2316 2327
17. T.M. Lee, C.C. Chan, S.H. Han, A.W. Leung, P.T. Fox, and J.H. Gao An event-related fMRI study on risk taking by healthy individuals of high or low impulsiveness Neurosci Lett 438 2008 138 141
18. M. Brand, E. Kalbe, K. Labudda, E. Fujiwara, J. Kessler, and H.J. Markowitsch Decision-making impairments in patients with pathological gambling Psychiatry Res 133 2005 91 99 (Pubitemid 40215475)
19. M. Hsu, M. Bhatt, R. Adolphs, D. Tranel, and C.F. Camerer Neural systems responding to degrees of uncertainty in human decision-making Science 310 2005 1680 1683 (Pubitemid 41780790)
20. Lejuez CW, Read JP, Kahler CW, Richards JB, Ramsey SE, Stuart GL, et al. Evaluation of a behavioral measure of risk taking: the Balloon Analogue Risk Task (BART). J Exp Psychol Appl. 200;2:75-84
21. H. Rao, M. Korczykowski, J. Pluta, A. Hoang, and J.A. Detre Neural correlates of voluntary and involuntary risk taking in the human brain: an fMRI Study of the Balloon Analog Risk Task (BART) Neuroimage 42 2008 902 910
22. T. Torralva, C.M. Kipps, J.R. Hodges, L. Clark, T. Bekinschtein, and M. Roca The relationship between affective decision-making and theory of mind in the frontal variant of fronto-temporal dementia Neuropsychologia 45 2007 342 349 (Pubitemid 44828770)
23. R.D. Rogers, A.M. Owen, H.C. Middleton, E.J. Williams, J.D. Pickard, and B.J. Sahakian Choosing between small, likely rewards and large, unlikely rewards activates inferior and orbital prefrontal cortex Neurosci. 19 1999 9029 9038 (Pubitemid 30226722)
24. E.T. Rolls The orbitofrontal cortex Philos Trans R Soc Lond B Biol Sci 351 1996 1433 1443
25. R. Dias, T.W. Robbins, and A.C. Roberts Dissociation in prefrontal cortex of affective and attentional shifts Nature 380 1996 69 72 (Pubitemid 26076238)
26. M. Wittmann, and M.P. Paulus Decision making, impulsivity and time perception Trends Cogn Sci 12 2008 7 12 (Pubitemid 350300034)
27. K.N. Kirby, and M. Santiesteban Concave utility, transaction costs, and risk in measuring discounting of delayed rewards J Exp Psychol Learn Mem Cogn 29 2003 66 79 (Pubitemid 37177388)
28. D. Laibson Golden eggs and hyperbolic discounting Q. J. Econ. 112 1997 443 477
29. G. Ainslie Specious reward - behavioral theory of impulsiveness and impulse control Psychol Bull 82 1975 463 496
30. S.D. Lane, D.R. Cherek, C.J. Pietras, and O.V. Tcheremissine Measurement of delay discounting using trial by-trial consequences Behav Processes 64 2003 287 303 (Pubitemid 37324374)
31. G.J. Madden, A.M. Begotka, B.R. Raiff, and L.L. Kastern Delay discounting of real and hypothetical rewards Exp Clin Psychopharmacol 11 2003 139 145 (Pubitemid 36547229)
32. S.M. McClure, D.I. Laibson, G. Loewenstein, and J.D. Cohen Separate neural systems value immediate and delayed monetary rewards Science 306 2004 503 507 (Pubitemid 39372453)
33. S.M. McClure, K.M. Ericson, D.I. Laibson, G. Loewenstein, and J.D. Cohen Time discounting for primary rewards J Neurosci 27 2007 5796 5804 (Pubitemid 350021085)
34. S.C. Tanaka, K. Doya, G. Okada, K. Ueda, Y. Okamoto, and S. Yamawaki Prediction of immediate and future rewards differentially recruits cortico-basal ganglia loops Nat Neurosci 7 2004 887 893 (Pubitemid 38989513)
35. M.J. Frank, L.C. Seeberger, and R.C. O'Reilly By carrot or by stick: cognitive reinforcement learning in Parkinsonism Science 306 2004 1940 1943 (Pubitemid 39627859)
36. M.J. Frank, J. Samanta, A.A. Moustafa, and S.J. Sherman Hold your horses: impulsivity, deep brain stimulation, and medication in Parkinsonism Science 318 2007 1309 1312 (Pubitemid 350172897)
37. L.K. Fellows, and M.J. Farah Different underlying impairments in decision-making following ventromedial and dorsolateral frontal lobe damage in humans Cereb Cortex 15 2005 58 63 (Pubitemid 40019052)
38. J. O'Doherty, M.L. Kringelbach, E.T. Rolls, J. Hornak, and C. Andrews Abstract reward and punishment representations in the human orbitofrontal cortex Nat Neurosci 4 2001 95 102 (Pubitemid 32095532)
39. M.J. Frank Hold your horses: a dynamic computational role for the subthalamic nucleus in decision making Neural Netw 19 2006 1120 1136 (Pubitemid 44466333)
40. D.G. Beiser, and J.C. Houk Model of cortical-basal ganglionic processing: encoding the serial order of sensory events J Neurophysiol 79 1998 3168 3188 (Pubitemid 28317043)
41. J. Brown, D. Bullock, and S. Grossberg How the basal ganglia use parallel excitatory and inhibitory learning pathways to selectively respond to unexpected rewarding cues J Neurosci 19 1999 10502 10511 (Pubitemid 30228056)
42. J.W. Brown, D. Bullock, and S. Grossberg How laminar frontal cortex and basal ganglia circuits interact to control planned and reactive saccades Neural Netw 17 2004 May 471 510 (Pubitemid 38510335)
43. M.J. Frank, B. Loughry, and R.C. O'Reilly Interactions between frontal cortex and basal ganglia in working memory: a computational model Cogn Affect Behav Neurosci 1 2001 137 160 (Pubitemid 38392490)
44. M.J. Frank, and R.C. O'Reilly A mechanistic account of striatal dopamine function in human cognition: psychopharmacological studies with cabergoline and haloperidol Behav Neurosci 120 2006 497 517 (Pubitemid 44050530)
45. M. Pessiglione, B. Seymour, G. Flandin, R.J. Dolan, and C.D. Frith Dopamine-dependent prediction errors underpin reward-seeking behaviour in humans Nature 442 2006 1042 1045 (Pubitemid 44330261)
46. A.E. Goudriaan, J. Oosterlaan, E. De Beurs, and W. Van Den Brink The role of self-reported impulsivity and reward sensitivity versus neurocognitive measures of disinhibition and decision-making in the prediction of relapse in pathological gamblers Psychol Med 38 2008 41 50 (Pubitemid 350275203)
47. A.J. Lawrence, J. Luty, N.A. Bogdan, B.J. Sahakian, and L. Clark Impulsivity and response inhibition in alcohol dependence and problem gambling Psychopharmacology (Berl). 207 2009 163 172
48. P.N. Dannon, N. Shoenfeld, O. Rosenberg, S. Kertzman, and M. Kotler Pathological gambling: an impulse control disorder? Measurement of impulsivity using neurocognitive tests Isr Med Assoc J 12 2010 243 248
49. E. Congdon, J.A. Mumford, J.R. Cohen, A. Galvan, A.R. Aron, and G. Xue Engagement of large-scale networks is related to individual differences in inhibitory control Neuroimage 53 2010 653 663
50. A.R. Aron, and R.A. Poldrack Cortical and subcortical contributions to stop signal response inhibition: role of the subthalamic nucleus J Neurosci 26 2006 2424 2433 (Pubitemid 44699002)
51. C.S. Li, P. Yan, R. Sinha, and T.W. Lee Subcortical processes of motor response inhibition during a stop signal task Neuroimage 41 2008 1352 1363
52. A.R. Aron From reactive to proactive and selective control: developing a richer model for stopping inappropriate responses Biol Psychiatry 2010 Oct 5 [Epub ahead of print]
53. M. Vink, R.S. Kahn, M. Raemaekers, M. van den Heuvel, M. Boersma, and N.F. Ramsey Function of striatum beyond inhibition and execution of motor responses Hum Brain Mapp 25 2005 Jul 336 344 (Pubitemid 40911344)
54. N. Ray, and A.P. Strafella Dopamine, reward, and frontostriatal circuitry in impulse control disorders in Parkinson's disease: insights from functional imaging Clin EEG Neurosci 41 2010 87 93
55. D. Weintraub, J. Koester, M.N. Potenza, A.D. Siderowf, M. Stacy, and V. Voon Impulse control disorders in Parkinson disease: a cross-sectional study of 3090 patients Arch Neurol 67 2010 589 595
56. M. Poletti, D. Frosini, C. Lucetti, P. Del Dotto, R. Ceravolo, and U. Bonuccelli Decision making in de novo Parkinson's disease Mov Disord 25 2010 1432 1436
57. N. Ibarretxe-Bilbao, C. Junque, E. Tolosa, M.J. Marti, F. Valldeoriola, and N. Bargallo Neuroanatomical correlates of impaired decision-making and facial emotion recognition in early Parkinson's disease Eur J Neurosci 30 2009 1162 1171
58. M. Delazer, H. Sinz, L. Zamarian, H. Stockner, K. Seppi, and G.K. Wenning Decision making under risk and under ambiguity in Parkinson's disease Neuropsychologia 47 2009 1901 1908
59. V. Czernecki, B. Pillon, J.L. Houeto, J.B. Pochon, R. Levy, and B. Dubois Motivation, reward, and Parkinson's disease: influence of dopatherapy Neuropsychologia 40 2002 2257 2267 (Pubitemid 35303365)
60. F. Euteneuer, F. Schaefer, R. Stuermer, W. Boucsein, L. Timmermann, and M.T. Barbe Dissociation of decision-making under ambiguity and decision-making under risk in patients with Parkinson's disease: a neuropsychological and psychophysiological study Neuropsychologia 47 2009 2882 2890
61. M. Poletti, P. Cavedini, and U. Bonuccelli Iowa gambling task in Parkinson's disease J Clin Exp Neuropsychol 6 2010 1 15
62. R.M. Spencer, and R.B. Ivry Comparison of patients with Parkinson's disease or cerebellar lesions in the production of periodic movements involving event-based or emergent timing Brain Cogn 58 2005 84 93 (Pubitemid 40692881)
63. M.A. Pastor, M. Jahanshahi, J. Artieda, and J.A. Obeso Performance of repetitive wrist movements in Parkinson's disease Brain 115 1992 875 891
64. C. Malapani, B. Rakitin, R. Levy, W.H. Meck, B. Deweer, and B. Dubois Coupled temporal memories in Parkinson's disease: a dopamine-related dysfunction J Cogn Neurosci 10 1998 316 331 (Pubitemid 28247945)
65. G. Koch, L. Brusa, C. Caltagirone, M. Oliveri, A. Peppe, and P. Tiraboschi Subthalamic deep brain stimulation improves time perception in Parkinson's disease Neuroreport 29 15 2004 1071 1073 (Pubitemid 38591265)
66. M. Rossi, E.R. Gerschcovich, D. de Achaval, S. Perez-Loret, D. Cerquetti, and A. Cammarota Decision making in Parkinson's disease patients with and without pathological gambling Eur J Neurol 1 17 2010 97 102
67. C.R. Housden, S.S. O'Sullivan, E.M. Joyce, A.J. Lees, and J.P. Roiser Intact reward learning but elevated delay discounting in Parkinson's disease patients with impulsive-compulsive spectrum behaviours Neuropsychopharmacology 35 11 2010 2155 2164
68. D. Frosini, I. Pesaresi, M. Cosottini, G. Belmonte, C. Rossi, and L. Dell'Osso Parkinson's disease and pathological gambling: results from a functional MRI study Mov Disord 25 2010 2449 2453
69. H. Rao, E. Mamikonyan, J.A. Detre, A. Siderowf, M. Stern, and M. Potenza Decreased ventral striatal activity with impulse control disorders in Parkinson's disease Mov Disord 25 2011 1660 1669
70. T.D. Steeves, J. Miyasaki, M. Zurowski, A.E. Lang, G. Pellecchia, and T. Van Eimeren Increased striatal dopamine release in Parkinsonian patients with pathological gambling: a [11C] raclopride PET study Brain 132 2009 1376 1385
71. R. Cilia, J.H. Ko, S.S. Cho, T. van Eimeren, G. Marotta, and G. Pellecchia Reduced dopamine transporter density in the ventral striatum of patients with Parkinson's disease and pathological gambling Neurobiol Dis 39 2010 98 104
72. N.D. Volkow, G.J. Wang, F. Telang, J.S. Fowler, J. Logan, and A.R. Childress Cocaine cues and dopamine in dorsal striatum: mechanism of craving in cocaine addiction J Neurosci 26 2006 6583 6588 (Pubitemid 44318339)
73. N.D. Volkow, J.S. Fowler, G.J. Wang, J.M. Swanson, and F. Telang Dopamine in drug abuse and addiction: results of imaging studies and treatment implications Arch Neurol 64 2007 1575 1579 (Pubitemid 350106758)
74. T. van Eimeren, G. Pellecchia, R. Cilia, B. Ballanger, T.D. Steeves, and S. Houle Drug-induced deactivation of inhibitory networks predicts pathological gambling in PD Neurology 75 2010 1711 1716
75. A. Djamshidian, A. Jha, S. O'Sullivan, L. Silveira-Moriyama, C. Jacobson, and P. Brown Risk and learning in impulsive and non-impulsive patients with Parkinson's Disease Mov Disord 25 2010 2203 2210
76. T. van Eimeren, B. Ballanger, G. Pellecchia, J.M. Miyasaki, A.E. Lang, and A.P. Strafella Dopamine agonists diminish value sensitivity of the orbitofrontal cortex: a trigger for pathological gambling in Parkinson's disease? Neuropsychopharmacology 34 2009 2758 2766
77. V. Voon, M. Pessiglione, C. Brezing, C. Gallea, H.H. Fernandez, and R.J. Dolan Mechanisms underlying dopamine-mediated reward bias in compulsive behaviors Neuron 65 2010 135 142
78. A. Pine, T. Shiner, B. Seymour, and R.J. Dolan Dopamine, time, and impulsivity in humans J Neurosci 30 2010 8888 8896
79. J.R. St Onge, and S.B. Floresco Dopaminergic modulation of risk-based decision making Neuropsychopharmacology 34 2009 681 697
80. F. Antonelli, N. Ray, and A.P. Strafella Imaging cognitive and behavioural symptoms in Parkinson's disease Expert Rev Neurothe 10 2010 1827 1838
81. H.M. Smeding, A.E. Goudriaan, E.M. Foncke, P.R. Schuurman, J.D. Speelman, and B. Schmand Pathological gambling after bilateral subthalamic nucleus stimulation in Parkinson disease J Neurol Neurosurg Psychiatry 78 2007 517 519 (Pubitemid 46662902)
82. G. Oyama, Y. Shimo, S. Natori, M. Nakajima, H. Ishii, and H. Arai Acute effects of bilateral subthalamic stimulation on decision-making in Parkinson's disease Parkinsonism Relat Disord 17 2011 189 193
83. V. Czernecki, B. Pillon, J.L. Houeto, M.L. Welter, V. Mesnage, and Y. Agid Does bilateral stimulation of the subthalamic nucleus aggravate apathy in Parkinson's disease? J Neurol Neurosurg Psychiatry 76 2005 775 779 (Pubitemid 40805805)
84. M.C. Rodriguez-Oroz, J. Lopez-Azcarte, D. Garcia-Garcia, M. Alegre, J. Toledo, and M. Valencia Involvement of the subthalamic nucleus in impulse control disorders associated with Parkinson's disease Brain 134 2011 34 49
85. S. Gauggel, M. Rieger, and T.A. Feghoff Inhibition of ongoing responses in patients with Parkinson's disease J Neurol Neurosurg Psychiatry 75 2004 539 544 (Pubitemid 38406648)
86. A.L. Benabid, S. Chabardes, J. Mitrofanis, and P. Pollak Deep brain stimulation of the subthalamic nucleus for the treatment of Parkinson's disease Lancet Neurol 8 2009 67 81
87. M. Jahanshahi, C.M. Ardouin, R.G. Brown, J.C. Rothwell, J. Obeso, and A. Albanese The impact of deep brain stimulation on executive function in Parkinson's disease Brain 123 2000 1142 1154 (Pubitemid 30312106)
88. T. Hershey, F.J. Revilla, A. Wernle, P.S. Gibson, J.L. Dowling, and J.S. Perlmutter Stimulation of STN impairs aspects of cognitive control in PD Neurology 62 2004 1110 1114 (Pubitemid 38456504)
89. K. Witt, U. Pulkowski, J. Herzog, D. Lorenz, W. Hamel, and G. Deuschl Deep brain stimulation of the subthalamic nucleus improves cognitive flexibility but impairs response inhibition in Parkinson disease Arch Neurol 6 2004 697 700 (Pubitemid 38637686)
90. M.C. Campbell, M. Karimi, P.M. Weaver, J. Wu, D.C. Perantie, and N.A. Golchin Neural correlates of STN DBS-induced cognitive variability in Parkinson disease Neuropsychologia 46 2008 3162 3169
91. B. Ballanger, T. van Eimeren, E. Moro, A.M. Lozano, C. Hamani, and P. Boulinguez Stimulation of the subthalamic nucleus and impulsivity: release your horses Ann Neurol 66 2009 817 824
92. N.J. Ray, N. Jenkinson, J. Brittain, P. Holland, C. Joint, and D. Nandi The role of the subthalamic nucleus in response inhibition: evidence from deep brain stimulation for Parkinson's disease Neuropsychologia 47 2009 Nov 2828 2834
93. S.A. Wylie, K.R. Ridderinkhof, W.J. Elias, R.C. Frysinger, T.R. Bashore, and K.E. Downs Subthalamic nucleus stimulation influences expression and suppression of impulsive behaviour in Parkinson's disease Brain 133 2010 3611 3624
94. T. Hershey, M.C. Campbell, T.O. Videen, H.M. Lugar, P.M. Weaver, and J. Hartlein Mapping Go-No-Go performance within the subthalamic nucleus region Brain 133 2010 3625 3634