Choosing between small, likely rewards and large, unlikely rewards activates inferior and orbital prefrontal cortex

Journal of Neuroscience

Volumn 19, Issue 20, 1999, Pages 9029-9038

  Rogers, Robert D ^a   Owen, Adrian M ^b   Middleton, Hugh C ^c   Williams, Emma J ^d   Pickard, John D ^e   Sahakian, Barbara J ^f   Robbins, Trevor W ^g  

^a UK   (United Kingdom)

^b MRC COGNITION AND BRAIN SCIENCES UNIT   (United Kingdom)

^c UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^e Department of Neurosurgery ^*  (United Kingdom)

^f ADDENBROOKE S HOSPITAL   (United Kingdom)

^g UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Decision making; Executive function; Frontal lobes; H2 15O PET; Orbitolateral PFC; Orbitomedial PFC

Indexed keywords

ADULT; ARTICLE; BEHAVIOR; BRAIN BLOOD FLOW; BRAIN CORTEX LESION; CINGULATE GYRUS; COGNITION; DECISION MAKING; HUMAN; HUMAN EXPERIMENT; MALE; NERVE CELL; NORMAL HUMAN; ORBITAL CORTEX; PREFRONTAL CORTEX; PRIORITY JOURNAL; REWARD;

EID: 0033570330     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.19-20-09029.1999     Document Type: Article

References (55)

1. Barbas H (1988) Anatomic organization of basoventral and mediodorsal visual recipient prefrontal regions in the rhesus monkey. J Comp Neurol 276:313-342.
2. Barbas H, Pandya DN (1989) Architecture and intrinsic connections of the prefrontal cortex in the rhesus monkey. J Comp Neurol 286:353-375.
3. Bechara A, Damasio AR, Damasio H, Anderson SW (1994) Insensitivity to future consequences following damage to human prefrontal cortex. Cognition 50:7-15.
4. Bechara A, Tranel D, Damasio H, Damasio AR (1996) Failure to respond autonomically to anticipated future outcomes following damage to prefrontal cortex. Cereb Cortex 6:215-225.
5. Bechara A, Damasio H, Tranel D, Damasio AR (1997) Deciding advantageously before knowing the advantageous strategy. Science 275:1293-1295.
6. Bechara A, Damasio H, Tranel D, Andersen SW (1998) Dissociation of working memory from decision-making within human prefrontal cortex. J Neurosci 18:428-437.
7. Bechara A, Damasio H, Damasio AR, Lee GP (1999) Different contri-butions of the human amygdala and ventromedial prefrontal cortex to decision-making. J Neurosci 19:5473-5481.
8. Berman KF, Randolph C, Gold J, Goldberg TE, Coppola R, Ostrem JL, Carson RE, Herscovitch P, Weinberger DR (1995) Physiological activation of a cortical network of the Wisconsin Card Sorting Test: a positron emission tomography study. Neuropsychologia 33:1027-1046.
9. Carmichael ST, Price JL (1994) Architectonic subdivision of the orbital and medial prefrontal cortex in the macaque monkey. J Comp Neurol 346:366-402.
10. Carmichael ST, Price JL (1995a) Limbic connections of the orbital cortex and medial prefrontal cortex in macaque monkeys. J Comp Neurol 363:615-641.
11. Carmichael ST, Price JL (1995b) Sensory and premotor connections of the orbital and medial prefrontal cortex of macaque monkeys. J Comp Neurol 363:642-664.
12. Courtney SM, Ungerleider LG, Keil K, Haxby JV (1997) Transient and sustained activity in a distributed neural system for human working memory. Nature 386:608-611.
13. Damasio AR (1994) Descartes' error. New York: Grosset/Putnam.
14. Damasio AR (1996a) The somatic marker hypothesis and the possible functions of the prefrontal cortex. Philos Trans R Soc Lond B Biol Sci 351:1413-1420.
15. Damasio H (1996b) Human neuroanatomy relevant to decision-making. In: Neurobiology of decision-making (Damasio AR, ed), pp 1-12. Berlin: Springer.
16. Damasio AR, Tranel D, Damasio H (1990) Individuals with sociopathic behavior caused by frontal damage fail to respond autonomically to social stimuli. Behav Brain Res 4:81-94.
17. Dias R, Robbins TW, Roberts AC (1996) Disassociation in prefrontal cortex of affective and attentional shifts. Nature 380:69-72.
18. DiChiara G, Imperato A (1988) Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proc Natl Acad Sci USA 85:5274-5278.
19. Elliott R, Friston KJ, Dolan RJ (1999) Dissociable neural response associated with reward, punishment and risk-taking. NeuroReport 9:S355.
20. Eslinger PJ, Damasio AR (1985) Severe disturbance of higher cognition after bilateral frontal lobe ablation: patient EVR. Neurology 35:1731-1741.
21. Friston KJ, Holmes AP, Worsley KJ, Poline J-B, Frith CD, Frackowiak RSJ (1995) Statistical parametric maps in functional imaging: a general approach. Hum Brain Mapp 2:189-210.
22. Goldman-Rakic PS (1987) Circuitry of primate prefrontal cortex and regulation of behaviour by representational knowledge. In: Handbook of physiology, Vol 5 (Plum F, Mountcastle VB, eds), pp 373-417. Bethesda, MD: American Physiological Society.
23. Goldman-Rakic PS (1994) The issue of memory in the study of prefrontal functions. In: Motor and cognitive functions of the prefrontal cortex (Thierry AM, Glowinski J, Goldman-Rakic PS, Christen Y, eds), pp 112-122. Berlin: Springer.
24. Goldman-Rakic PS (1996) The prefrontal landscape: implications of functional architecture for understanding human mentation and the central executive. Philos Trans R Soc Lond B Biol Sci 351:1445-1453.
25. Haber SN, Kunisho K, Mizobuchi M, Lynd-Balta E (1995) The orbital and medial prefrontal circuit through the primate basal ganglia. J Neurosci 15:4851-4867.
26. Howell DC (1987) Statistical methods for psychology, Ed 2. Boston: Duxbury.
27. Iversen SD, Mishkin M (1970) Perseverative interference in monkeys following selective lesions of the inferior prefrontal convexity. Exp Brain Res 11:376-386.
28. Jones EG, Powell TPS (1970) An anatomical study of converging sensory pathways within the cerebral cortex of the monkey. Brain 93:793-820.
29. Jones B, Mishkin M (1972) Limbic lesions and the problem of stimulusreinforcement associations. Exp Neurology 36:362-377.
30. Kawashima R, Satoh K, Itoh H, Ono S, Furumoto S, Gotoh R, Koyama M, Yoshioka S, Takahashi T, Takahashi K, Yanagisawa T, Fukuda H (1996) Functional anatomy of GO/NO-GO discrimination and response selection-a PET study in man. Brain Res 728:79-89.
31. KonishiS,NakajimaK,UchidaI, SekiharaK,Miyashita Y (1998) No-go dominant brain activity in human inferior prefrontal cortex revealed by functional magnetic resonance imaging. Eur J Neurosci 10:1209-1213.
32. KoobGF, Bloom FE (1988) Cellular and molecular mechanisms of drug dependence. Science 242:715-723.
33. Krams M, Rushworth M FS, Deiber M P, Frackowiak RSJ, Passingham RE (1998) The preparation, execution and suppression of copied movements in the human brain. Exp Brain Res 120:386-398.
34. Linnoila M, Virkkunen M, Stein M, Nuptial A, Ripon R, Goodwill FK (1983) Low cerebrospinal fluid 5-hydroxyindoleacetic acid differentiates impulsive from nonimpulsive violent behavior. Life Sci 33:2609-2614.
35. Milner B (1964) Some effects of frontal lobectomy in man. In: The frontal granular cortex and behavior (Warren JM, Akert K, eds). New York: McGraw-Hill.
36. Morecroft RJ, Geula C, Mesulam M-M (1992) Cytoarchitecture and neural afferents of orbitofrontal cortex in the brain of the monkey. J Comp Neural 323:341-358.
37. Nelson HE (1982) National adult reading test (NART) test manual. Windsor: NFER-Nelson.
38. Nobre AC, Coull JT, CD Frith (1999) Orbitofrontal cortex is activated during breaches of expectation in tasks of visual attention. Nat Neurosci 2:11-12.
39. Owen AM, Evans AC, Petrides M (1996) Evidence for a two-stage model of spatial working memory within the lateral frontal cortex: a positron emission tomography study. Cereb Cortex 6:31-38.
40. Petrides M (1994) Frontal lobes and working memory: evidence from investigations of the effects of cortical excision in human primates. In: Handbook of neuropsychology, Vol 9 (Boiler F, Grafman J, eds), pp 59-82. Elsevier: Amsterdam.
41. Petrides M (1995) Functional organisation of the human frontal cortex for mnemonic processing. Ann NY Acad Sci 76:85-96.
42. Petrides M (1996) Specialized systems for the processing of mnemonic information within the primate frontal cortex. Philos Trans R Soc B Biol Sci 351:1455-1461.
43. Rahman S, Sahakian BJ, Hodges JR, Rogers RD, Robbins TW (1999) Specific cognitive deficits in mild frontal variant frontotemporal dementia. Brain 122:1469-1493.
44. Roberts AC, Robbins TW, Weiskrantz L (1996) Executive and cognitive functions of the prefrontal cortex. Philos Trans R Soc Lond B Biol Sci 351:1387-1527.
45. Rogers RD, Everitt BJ, Baldacchino A, Blackmore AJ, Swainson R, London M, Deakin JWF, Sahakian BJ, Robbins TW (1999) Dissociating deficits in the decision-making cognition of chronic amphetamine abusers, opiate abusers, patients with focal damage to prefrontal cortex, and tryptophan-depleted normal volunteers: evidence for monoaminergic mechanisms. Neuropsychopharmacology 20:322-329.
46. Rolls ET, Hornak J, Wade D, McGrath J (1994) Emotion-related learning in patients with social and emotional changes associated with frontal lobe damage. J Neurol Neurosurg Psychiatry 57:1518-1524.
47. Rolls ET (1996) The orbitofrontal cortex. Philos Trans R Soc Lond B Biol Sci 351:1433-1444.
48. Saver JL, Damasio AR (1991) Preserved access and processing of social knowledge in a patient with acquired sociopathy due to ventromedial frontal damage. Neuropsychologia 29:1241-1249.
49. 15O regional cerebral blood flow threedimensional imaging technique. J Cen:b Blood Flow Metab 13:617-629.
50. Smith EE, Jonides J, Koeppe RA (1996) Dissociating verbal and spatial and working memory using PET. Cereb Cotex 6:11-20.
51. Stuss DT, Benson DF (1986) The frontal lobi-s. New York: Raven.
52. Thierry AM, Blanc G, Sobel A, Stinus L, Glow inski J (1973) Dopamine terminals in the rat cortex. Science 182:499-501.
53. Vogt BA, Finch DM, Oison CR (1992) Functional heterogeneity in cingulate cortex: the anterior executive and posterior evaluative regions. Cereb Cortex 2:435-443.
54. Wise RA, Rompre PP (1989) Brain dopamine and reward. Annu Rev Psychol 40:191-225.
55. Worsley KJ, Marrett S, Neelin P, Vandal AC, Friston KJ, Evans AC (1996) A unified statistical approach for determining significant signals in images of cerebral activation. Hum Brair Mapp 4:58-73.