Corticotropin releasing factor-1 receptor antagonism alters the biochemical, but not behavioral effects of repeated interleukin-1β administration

Neuropharmacology

Volumn 62, Issue 1, 2012, Pages 313-321

  Wilhelm, Clare J ^a,b   Murphy Crews, Aaron ^c   Menasco, Daniel J ^a   Huckans, Marilyn S ^a,b   Loftis, Jennifer M ^a,b,c  

^a PORTLAND VA MEDICAL CENTER   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c REED COLLEGE   (United States)

Author keywords

Corticotropin releasing factor; Cytokines; Forced swim test; Interleukin 1beta; p38 MAPK; Sickness behavior; Weight regulation

Indexed keywords

4 (3 PENTYLAMINO) 2,7 DIMETHYL 8 (2 METHYL 4 METHOXYPHENYL)PYRAZOLO [1,5 A]PYRIMIDINE; CORTICOTROPIN RELEASING FACTOR ANTAGONIST; CORTICOTROPIN RELEASING FACTOR RECEPTOR 1; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE P38; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BODY WEIGHT; BRAIN REGION; BRAIN TISSUE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FORCED SWIMMING TEST; HIPPOCAMPUS; HYPOTHALAMUS; ILLNESS BEHAVIOR; IMMOBILIZATION; IMMUNE SYSTEM; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT;

ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; BODY WEIGHT; BRAIN; CORTICOTROPIN-RELEASING HORMONE; CYTOKINES; DRUG ADMINISTRATION SCHEDULE; GENE EXPRESSION REGULATION; HUMANS; IMMOBILITY RESPONSE, TONIC; INTERLEUKIN-1BETA; MALE; MOVEMENT; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PYRAZOLES; PYRIMIDINES; RATS; RATS, WISTAR; STATISTICS AS TOPIC; SWIMMING; TIME FACTORS;

EID: 80054092765     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2011.07.040     Document Type: Conference Paper

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