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Volumn 77, Issue 4-5, 2011, Pages 371-380

Hypomethylating drugs efficiently decrease cytosine methylation in telomeric DNA and activate telomerase without affecting telomere lengths in tobacco cells

Author keywords

Cell culture; DNA methylation; Hypomethylating agents; Nicotiana tabacum; Telomere; Zebularine

Indexed keywords

9 (2,3 DIHYDROXYPROPYL)ADENINE; 9-(2,3-DIHYDROXYPROPYL)ADENINE; ADENINE; CYTIDINE; DRUG DERIVATIVE; PLANT DNA; PYRIMIDIN 2 ONE BETA RIBOFURANOSIDE; PYRIMIDIN-2-ONE BETA-RIBOFURANOSIDE; TELOMERASE; VEGETABLE PROTEIN;

EID: 80054047834     PISSN: 01674412     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11103-011-9816-7     Document Type: Article
Times cited : (26)

References (63)
  • 1
    • 58849132900 scopus 로고    scopus 로고
    • Effective, homogeneous and transient interference with cytosine methylation in plant genomic DNA by zebularine
    • doi:10.1111/j.1365-313X.2008.03699.x
    • Baubec T, Pecinka A, Rozhon W, Mittelsten Scheid O (2009) Effective, homogeneous and transient interference with cytosine methylation in plant genomic DNA by zebularine. Plant J 57(3): 542-554. doi: 10. 1111/j. 1365-313X. 2008. 03699. x.
    • (2009) Plant J , vol.57 , Issue.3 , pp. 542-554
    • Baubec, T.1    Pecinka, A.2    Rozhon, W.3    Mittelsten Scheid, O.4
  • 2
    • 0017801980 scopus 로고
    • Isolation, characterization, and properties of a labile hydrolysis product of the antitumor nucleoside, 5-azacytidine
    • Beisler JA (1978) Isolation, characterization, and properties of a labile hydrolysis product of the antitumor nucleoside, 5-azacytidine. J Med Chem 21(2): 204-208.
    • (1978) J Med Chem , vol.21 , Issue.2 , pp. 204-208
    • Beisler, J.A.1
  • 3
    • 33846590977 scopus 로고    scopus 로고
    • Telomere length regulates the epigenetic status of mammalian telomeres and subtelomeres
    • doi:10.1038/ng1952
    • Benetti R, Garcia-Cao M, Blasco MA (2007) Telomere length regulates the epigenetic status of mammalian telomeres and subtelomeres. Nat Genet 39(2): 243-250. doi: 10. 1038/ng1952.
    • (2007) Nat Genet , vol.39 , Issue.2 , pp. 243-250
    • Benetti, R.1    Garcia-Cao, M.2    Blasco, M.A.3
  • 4
    • 0037058968 scopus 로고    scopus 로고
    • Locus-specific control of asymmetric and CpNpG methylation by the DRM and CMT3 methyltransferase genes
    • doi:10.1073/pnas.162371599
    • Cao X, Jacobsen SE (2002a) Locus-specific control of asymmetric and CpNpG methylation by the DRM and CMT3 methyltransferase genes. Proc Natl Acad Sci USA 99(Suppl 4): 16491-16498. doi: 10. 1073/pnas. 162371599.
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.SUPPL. 4 , pp. 16491-16498
    • Cao, X.1    Jacobsen, S.E.2
  • 5
    • 0037046810 scopus 로고    scopus 로고
    • Role of the Arabidopsis DRM methyltransferases in de novo DNA methylation and gene silencing
    • doi:S0960982202009259
    • Cao X, Jacobsen SE (2002b) Role of the Arabidopsis DRM methyltransferases in de novo DNA methylation and gene silencing. Curr Biol 12(13): 1138-1144. doi: S0960982202009259.
    • (2002) Curr Biol , vol.12 , Issue.13 , pp. 1138-1144
    • Cao, X.1    Jacobsen, S.E.2
  • 7
    • 67650252226 scopus 로고    scopus 로고
    • RNA-directed DNA methylation and demethylation in plants
    • doi:10.1007/s11427-009-0052-1
    • Chinnusamy V, Zhu JK (2009) RNA-directed DNA methylation and demethylation in plants. Sci China C Life Sci 52(4): 331-343. doi: 10. 1007/s11427-009-0052-1.
    • (2009) Sci China C Life Sci , vol.52 , Issue.4 , pp. 331-343
    • Chinnusamy, V.1    Zhu, J.K.2
  • 8
    • 0016240205 scopus 로고
    • Biological effects of 5-azacytidine in eukaryotes
    • Cihak A (1974) Biological effects of 5-azacytidine in eukaryotes. Oncology 30(5): 405-422.
    • (1974) Oncology , vol.30 , Issue.5 , pp. 405-422
    • Cihak, A.1
  • 10
    • 0018090383 scopus 로고
    • (S)-9-(2, 3-Dihydroxypropyl)adenine: an aliphatic nucleoside analog with broad-spectrum antiviral activity
    • De Clercq E, Descamps J, De Somer P, Holy A (1978) (S)-9-(2, 3-Dihydroxypropyl)adenine: an aliphatic nucleoside analog with broad-spectrum antiviral activity. Science 200(4341): 563-565.
    • (1978) Science , vol.200 , Issue.4341 , pp. 563-565
    • de Clercq, E.1    Descamps, J.2    de Somer, P.3    Holy, A.4
  • 12
    • 50549163302 scopus 로고
    • Distribution of 5-methylcytosine in pyrimidine sequences of deoxyribonucleic acids
    • Doskocil J, Sorm F (1962) Distribution of 5-methylcytosine in pyrimidine sequences of deoxyribonucleic acids. Biochim Biophys Acta 55: 953-959.
    • (1962) Biochim Biophys Acta , vol.55 , pp. 953-959
    • Doskocil, J.1    Sorm, F.2
  • 13
    • 0034811153 scopus 로고    scopus 로고
    • Columnar packing of telomeric nucleosomes
    • doi:10.1006/bbrc.2000.4208
    • Fajkus J, Trifonov EN (2001) Columnar packing of telomeric nucleosomes. Biochem Biophys Res Commun 280(4): 961-963. doi: 10. 1006/bbrc. 2000. 4208.
    • (2001) Biochem Biophys Res Commun , vol.280 , Issue.4 , pp. 961-963
    • Fajkus, J.1    Trifonov, E.N.2
  • 14
    • 0026615280 scopus 로고
    • Changes in chromatin structure due to hypomethylation induced with 5-azacytidine or DL-ethionine
    • doi:0014-5793(92)81449-V
    • Fajkus J, Vyskot B, Bezdek M (1992) Changes in chromatin structure due to hypomethylation induced with 5-azacytidine or DL-ethionine. Febs Lett 314(1): 13-16. doi: 0014-5793(92)81449-V.
    • (1992) Febs Lett , vol.314 , Issue.1 , pp. 13-16
    • Fajkus, J.1    Vyskot, B.2    Bezdek, M.3
  • 15
    • 0029007358 scopus 로고
    • Organization of telomeric and subtelomeric chromatin in the higher plant Nicotiana tabacum
    • Fajkus J, Kovarik A, Kralovics R, Bezdek M (1995a) Organization of telomeric and subtelomeric chromatin in the higher plant Nicotiana tabacum. Mol Gen Genet 247(5): 633-638.
    • (1995) Mol Gen Genet , vol.247 , Issue.5 , pp. 633-638
    • Fajkus, J.1    Kovarik, A.2    Kralovics, R.3    Bezdek, M.4
  • 16
    • 0028928123 scopus 로고
    • The telomeric sequence is directly attached to the HRS60 subtelomeric tandem repeat in tobacco chromosomes
    • doi:0014-5793(95)00347-C
    • Fajkus J, Kralovics R, Kovarik A, Fajkusova L (1995b) The telomeric sequence is directly attached to the HRS60 subtelomeric tandem repeat in tobacco chromosomes. Febs Lett 364(1): 33-35. doi: 0014-5793(95)00347-C.
    • (1995) Febs Lett , vol.364 , Issue.1 , pp. 33-35
    • Fajkus, J.1    Kralovics, R.2    Kovarik, A.3    Fajkusova, L.4
  • 17
    • 0030581306 scopus 로고    scopus 로고
    • Telomerase activity in plant cells
    • doi:0014-5793(96)00757-0
    • Fajkus J, Kovarik A, Kralovics R (1996) Telomerase activity in plant cells. Febs Lett 391(3): 307-309. doi: 0014-5793(96)00757-0.
    • (1996) Febs Lett , vol.391 , Issue.3 , pp. 307-309
    • Fajkus, J.1    Kovarik, A.2    Kralovics, R.3
  • 18
    • 0345003923 scopus 로고    scopus 로고
    • Plant cells express telomerase activity upon transfer to callus culture, without extensively changing telomere lengths
    • Fajkus J, Fulneckova J, Hulanova M, Berkova K, Riha K, Matyasek R (1998) Plant cells express telomerase activity upon transfer to callus culture, without extensively changing telomere lengths. Mol Gen Genet 260(5): 470-474.
    • (1998) Mol Gen Genet , vol.260 , Issue.5 , pp. 470-474
    • Fajkus, J.1    Fulneckova, J.2    Hulanova, M.3    Berkova, K.4    Riha, K.5    Matyasek, R.6
  • 19
    • 0037192927 scopus 로고    scopus 로고
    • Tiptoeing to chromosome tips: facts, promises and perils of today's human telomere biology
    • doi:10.1098/rstb.2001.1053
    • Fajkus J, Simickova M, Malaska J (2002) Tiptoeing to chromosome tips: facts, promises and perils of today's human telomere biology. Philos Trans R Soc Lond B Biol Sci 357(1420): 545-562. doi: 10. 1098/rstb. 2001. 1053.
    • (2002) Philos Trans R Soc Lond B Biol Sci , vol.357 , Issue.1420 , pp. 545-562
    • Fajkus, J.1    Simickova, M.2    Malaska, J.3
  • 20
    • 79955124012 scopus 로고    scopus 로고
    • Epigenetic modifications in plants: an evolutionary perspective
    • doi:10.1016/j.pbi.2010.12.002
    • Feng S, Jacobsen SE (2011) Epigenetic modifications in plants: an evolutionary perspective. Curr Opin Plant Biol 14(2): 179-186. doi: 10. 1016/j. pbi. 2010. 12. 002.
    • (2011) Curr Opin Plant Biol , vol.14 , Issue.2 , pp. 179-186
    • Feng, S.1    Jacobsen, S.E.2
  • 21
    • 77955844757 scopus 로고    scopus 로고
    • TERRA biogenesis, turnover and implications for function
    • Feuerhahn S, Iglesias N, Panza A, Porro A, Lingner J (2010) TERRA biogenesis, turnover and implications for function. Febs Lett 584(17): 3812-3818.
    • (2010) Febs Lett , vol.584 , Issue.17 , pp. 3812-3818
    • Feuerhahn, S.1    Iglesias, N.2    Panza, A.3    Porro, A.4    Lingner, J.5
  • 22
    • 0027159975 scopus 로고
    • Isolation and identification by sequence homology of a putative cytosine methyltransferase from Arabidopsis thaliana
    • Finnegan EJ, Dennis ES (1993) Isolation and identification by sequence homology of a putative cytosine methyltransferase from Arabidopsis thaliana. Nucleic Acids Res 21(10): 2383-2388.
    • (1993) Nucleic Acids Res , vol.21 , Issue.10 , pp. 2383-2388
    • Finnegan, E.J.1    Dennis, E.S.2
  • 23
    • 0029955901 scopus 로고    scopus 로고
    • Characterization and developmental patterns of telomerase expression in plants
    • Fitzgerald MS, McKnight TD, Shippen DE (1996) Characterization and developmental patterns of telomerase expression in plants. Proc Natl Acad Sci USA 93(25): 14422-14427.
    • (1996) Proc Natl Acad Sci USA , vol.93 , Issue.25 , pp. 14422-14427
    • Fitzgerald, M.S.1    McKnight, T.D.2    Shippen, D.E.3
  • 24
    • 0032521589 scopus 로고    scopus 로고
    • Evaluation of the impact of S-adenosylhomocysteine metabolic pools on cytosine methylation of the tobacco genome
    • Fojtova M, Kovarik A, Votruba I, Holy A (1998) Evaluation of the impact of S-adenosylhomocysteine metabolic pools on cytosine methylation of the tobacco genome. Eur J Biochem 252(3): 347-352.
    • (1998) Eur J Biochem , vol.252 , Issue.3 , pp. 347-352
    • Fojtova, M.1    Kovarik, A.2    Votruba, I.3    Holy, A.4
  • 25
    • 0036841989 scopus 로고    scopus 로고
    • Recovery of tobacco cells from cadmium stress is accompanied by DNA repair and increased telomerase activity
    • Fojtova M, Fulneckova J, Fajkus J, Kovarik A (2002) Recovery of tobacco cells from cadmium stress is accompanied by DNA repair and increased telomerase activity. J Exp Bot 53(378): 2151-2158.
    • (2002) J Exp Bot , vol.53 , Issue.378 , pp. 2151-2158
    • Fojtova, M.1    Fulneckova, J.2    Fajkus, J.3    Kovarik, A.4
  • 26
    • 79952985249 scopus 로고    scopus 로고
    • Inhibition of SAH-hydrolase activity during seed germination leads to deregulation of flowering genes and altered flower morphology in tobacco
    • doi:10.1007/s00438-011-0601-8
    • Fulnecek J, Matyasek R, Votruba I, Holy A, Krizova K, Kovarik A (2011) Inhibition of SAH-hydrolase activity during seed germination leads to deregulation of flowering genes and altered flower morphology in tobacco. Mol Genet Genomics 285(3): 225-236. doi: 10. 1007/s00438-011-0601-8.
    • (2011) Mol Genet Genomics , vol.285 , Issue.3 , pp. 225-236
    • Fulnecek, J.1    Matyasek, R.2    Votruba, I.3    Holy, A.4    Krizova, K.5    Kovarik, A.6
  • 27
    • 0343986332 scopus 로고    scopus 로고
    • Inhibition of plant telomerase by telomere-binding proteins from nuclei of telomerase-negative tissues
    • doi:S0014-5793(00)01178-9
    • Fulneckova J, Fajkus J (2000) Inhibition of plant telomerase by telomere-binding proteins from nuclei of telomerase-negative tissues. Febs Lett 467(2-3): 305-310. doi: S0014-5793(00)01178-9.
    • (2000) Febs Lett , vol.467 , Issue.2-3 , pp. 305-310
    • Fulneckova, J.1    Fajkus, J.2
  • 28
    • 0347988045 scopus 로고    scopus 로고
    • Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases
    • doi:10.1038/ng1278
    • Garcia-Cao M, O'Sullivan R, Peters AH, Jenuwein T, Blasco MA (2004) Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases. Nat Genet 36(1): 94-99. doi: 10. 1038/ng1278.
    • (2004) Nat Genet , vol.36 , Issue.1 , pp. 94-99
    • Garcia-Cao, M.1    O'Sullivan, R.2    Peters, A.H.3    Jenuwein, T.4    Blasco, M.A.5
  • 29
    • 73249144150 scopus 로고    scopus 로고
    • DNA methylation in early development
    • doi:10.1002/mrd.21118
    • Geiman TM, Muegge K (2010) DNA methylation in early development. Mol Reprod Dev 77(2): 105-113. doi: 10. 1002/mrd. 21118.
    • (2010) Mol Reprod Dev , vol.77 , Issue.2 , pp. 105-113
    • Geiman, T.M.1    Muegge, K.2
  • 30
    • 34547799171 scopus 로고    scopus 로고
    • DNA methyltransferases as targets for cancer therapy
    • doi:10.1358/dot.2007.43.6.1062666
    • Ghoshal K, Bai S (2007) DNA methyltransferases as targets for cancer therapy. Drugs Today (Barc) 43(6): 395-422. doi: 10. 1358/dot. 2007. 43. 6. 1062666.
    • (2007) Drugs Today (Barc) , vol.43 , Issue.6 , pp. 395-422
    • Ghoshal, K.1    Bai, S.2
  • 31
    • 0035355340 scopus 로고    scopus 로고
    • Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes
    • doi:10.1093/emboj/20.11.2619
    • Gonzalez-Suarez E, Samper E, Ramirez A, Flores JM, Martin-Caballero J, Jorcano JL, Blasco MA (2001) Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes. EMBO J 20(11): 2619-2630. doi: 10. 1093/emboj/20. 11. 2619.
    • (2001) EMBO J , vol.20 , Issue.11 , pp. 2619-2630
    • Gonzalez-Suarez, E.1    Samper, E.2    Ramirez, A.3    Flores, J.M.4    Martin-Caballero, J.5    Jorcano, J.L.6    Blasco, M.A.7
  • 32
    • 33645702660 scopus 로고    scopus 로고
    • DNA methyltransferases control telomere length and telomere recombination in mammalian cells
    • doi:10.1038/ncb1386
    • Gonzalo S, Jaco I, Fraga MF, Chen T, Li E, Esteller M, Blasco MA (2006) DNA methyltransferases control telomere length and telomere recombination in mammalian cells. Nat Cell Biol 8(4): 416-424. doi: 10. 1038/ncb1386.
    • (2006) Nat Cell Biol , vol.8 , Issue.4 , pp. 416-424
    • Gonzalo, S.1    Jaco, I.2    Fraga, M.F.3    Chen, T.4    Li, E.5    Esteller, M.6    Blasco, M.A.7
  • 33
    • 0022402513 scopus 로고
    • Identification of a specific telomere terminal transferase activity in Tetrahymena extracts
    • doi:0092-8674(85)90170-9
    • Greider CW, Blackburn EH (1985) Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell 43(2 Pt 1): 405-413. doi: 0092-8674(85)90170-9.
    • (1985) Cell , vol.43 , Issue.1-2 , pp. 405-413
    • Greider, C.W.1    Blackburn, E.H.2
  • 34
    • 0023663881 scopus 로고
    • The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity
    • doi:0092-8674(87)90576-9
    • Greider CW, Blackburn EH (1987) The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity. Cell 51(6): 887-898. doi: 0092-8674(87)90576-9.
    • (1987) Cell , vol.51 , Issue.6 , pp. 887-898
    • Greider, C.W.1    Blackburn, E.H.2
  • 35
    • 0019875880 scopus 로고
    • Methylation of CpG sequences in eukaryotic DNA
    • doi:0014-5793(81)80055-5
    • Gruenbaum Y, Stein R, Cedar H, Razin A (1981) Methylation of CpG sequences in eukaryotic DNA. Febs Lett 124(1): 67-71. doi: 0014-5793(81)80055-5.
    • (1981) Febs Lett , vol.124 , Issue.1 , pp. 67-71
    • Gruenbaum, Y.1    Stein, R.2    Cedar, H.3    Razin, A.4
  • 36
    • 0035810735 scopus 로고    scopus 로고
    • High-performance liquid chromatographic determination of deoxycytidine monophosphate and methyldeoxycytidine monophosphate for DNA demethylation monitoring: experimental design and artificial neural networks optimisation
    • Havlis J, Madden JE, Revilla AL, Havel J (2001) High-performance liquid chromatographic determination of deoxycytidine monophosphate and methyldeoxycytidine monophosphate for DNA demethylation monitoring: experimental design and artificial neural networks optimisation. J Chromatogr B Biomed Sci Appl 755(1-2): 185-194.
    • (2001) J Chromatogr B Biomed Sci Appl , vol.755 , Issue.1-2 , pp. 185-194
    • Havlis, J.1    Madden, J.E.2    Revilla, A.L.3    Havel, J.4
  • 37
    • 0031832432 scopus 로고    scopus 로고
    • A DNA methyltransferase homolog with a chromodomain exists in multiple polymorphic forms in Arabidopsis
    • Henikoff S, Comai L (1998) A DNA methyltransferase homolog with a chromodomain exists in multiple polymorphic forms in Arabidopsis. Genetics 149(1): 307-318.
    • (1998) Genetics , vol.149 , Issue.1 , pp. 307-318
    • Henikoff, S.1    Comai, L.2
  • 38
    • 0037148326 scopus 로고    scopus 로고
    • Clinical utility of telomerase in cancer
    • doi:10.1038/sj.onc.1205070
    • Hiyama E, Hiyama K (2002) Clinical utility of telomerase in cancer. Oncogene 21(4): 643-649. doi: 10. 1038/sj. onc. 1205070.
    • (2002) Oncogene , vol.21 , Issue.4 , pp. 643-649
    • Hiyama, E.1    Hiyama, K.2
  • 39
    • 0016637535 scopus 로고
    • Aliphatic analogues of nucleosides, nucleotides and oligonucleotides
    • Holy A (1975) Aliphatic analogues of nucleosides, nucleotides and oligonucleotides. Collect Czech Chem Commun 40: 187-214.
    • (1975) Collect Czech Chem Commun , vol.40 , pp. 187-214
    • Holy, A.1
  • 40
    • 0019852904 scopus 로고
    • Embryotoxicity of 9-(S)-(2, 3-dihydroxypropyl)adenine
    • doi:10.1002/tera.1420240304
    • Jelinek R, Holy A, Votruba I (1981) Embryotoxicity of 9-(S)-(2, 3-dihydroxypropyl)adenine. Teratology 24(3): 267-275. doi: 10. 1002/tera. 1420240304.
    • (1981) Teratology , vol.24 , Issue.3 , pp. 267-275
    • Jelinek, R.1    Holy, A.2    Votruba, I.3
  • 41
    • 41149104371 scopus 로고    scopus 로고
    • Dyskerin is a component of the Arabidopsis telomerase RNP required for telomere maintenance
    • doi:MCB.01490-07
    • Kannan K, Nelson AD, Shippen DE (2008) Dyskerin is a component of the Arabidopsis telomerase RNP required for telomere maintenance. Mol Cell Biol 28(7): 2332-2341. doi: MCB. 01490-07.
    • (2008) Mol Cell Biol , vol.28 , Issue.7 , pp. 2332-2341
    • Kannan, K.1    Nelson, A.D.2    Shippen, D.E.3
  • 42
    • 0022519219 scopus 로고
    • Synthesis of pyrimidin-2-one nucleosides as acid-stable inhibitors of cytidine deaminase
    • Kim CH, Marquez VE, Mao DT, Haines DR, McCormack JJ (1986) Synthesis of pyrimidin-2-one nucleosides as acid-stable inhibitors of cytidine deaminase. J Med Chem 29(8): 1374-1380.
    • (1986) J Med Chem , vol.29 , Issue.8 , pp. 1374-1380
    • Kim, C.H.1    Marquez, V.E.2    Mao, D.T.3    Haines, D.R.4    McCormack, J.J.5
  • 44
    • 0036945115 scopus 로고    scopus 로고
    • Hypomethylation of CNG targets induced with dihydroxypropyladenine is rapidly reversed in the course of mitotic cell division in tobacco
    • doi:10.1007/s00122-002-1152-5
    • Koukalova B, Votruba I, Fojtova M, Holy A, Kovarik A (2002) Hypomethylation of CNG targets induced with dihydroxypropyladenine is rapidly reversed in the course of mitotic cell division in tobacco. Theor Appl Genet 105(6-7): 1097-1098. doi: 10. 1007/s00122-002-1152-5.
    • (2002) Theor Appl Genet , vol.105 , Issue.6-7 , pp. 1097-1098
    • Koukalova, B.1    Votruba, I.2    Fojtova, M.3    Holy, A.4    Kovarik, A.5
  • 45
    • 0028063069 scopus 로고
    • Sequence-specific hypomethylation of the tobacco genome induced with dihydroxypropyladenine, ethionine and 5-azacytidine
    • Kovarik A, Koukalova B, Holy A, Bezdek M (1994) Sequence-specific hypomethylation of the tobacco genome induced with dihydroxypropyladenine, ethionine and 5-azacytidine. Febs Lett 353(3): 309-311.
    • (1994) Febs Lett , vol.353 , Issue.3 , pp. 309-311
    • Kovarik, A.1    Koukalova, B.2    Holy, A.3    Bezdek, M.4
  • 47
    • 55749107116 scopus 로고    scopus 로고
    • Telomerase activity in head and neck cancer
    • Kunicka Z, Mucha I, Fajkus J (2008) Telomerase activity in head and neck cancer. Anticancer Res 28(5B): 3125-3129.
    • (2008) Anticancer Res , vol.28 , Issue.5 B , pp. 3125-3129
    • Kunicka, Z.1    Mucha, I.2    Fajkus, J.3
  • 48
    • 77957794732 scopus 로고    scopus 로고
    • Tobacco GTBP1, a homolog of human heterogeneous nuclear ribonucleoprotein, protects telomeres from aberrant homologous recombination
    • doi:tpc.110.076778
    • Lee YW, Kim WT (2010) Tobacco GTBP1, a homolog of human heterogeneous nuclear ribonucleoprotein, protects telomeres from aberrant homologous recombination. Plant Cell 22(8): 2781-2795. doi: tpc. 110. 076778.
    • (2010) Plant Cell , vol.22 , Issue.8 , pp. 2781-2795
    • Lee, Y.W.1    Kim, W.T.2
  • 49
    • 23444436522 scopus 로고
    • Evidence for cytosine methylation of non-symmetrical sequences in transgenic Petunia hybrida
    • Meyer P, Niedenhof I, ten Lohuis M (1994) Evidence for cytosine methylation of non-symmetrical sequences in transgenic Petunia hybrida. EMBO J 13(9): 2084-2088.
    • (1994) EMBO J , vol.13 , Issue.9 , pp. 2084-2088
    • Meyer, P.1    Niedenhof, I.2    Ten Lohuis, M.3
  • 50
    • 0026568783 scopus 로고
    • Tobacco BY-2 cell line as the "HeLa" cell in the cell biology of higher plants
    • Nagata T, Nemoto Y, Hasezawa S (1992) Tobacco BY-2 cell line as the "HeLa" cell in the cell biology of higher plants. Int Rev Cytol 112: 1-30.
    • (1992) Int Rev Cytol , vol.112 , pp. 1-30
    • Nagata, T.1    Nemoto, Y.2    Hasezawa, S.3
  • 51
    • 62549122535 scopus 로고    scopus 로고
    • Telomerase activity is associated with an increase in DNA methylation at the proximal subtelomere and a reduction in telomeric transcription
    • doi:10.1093/nar/gkn1030
    • Ng LJ, Cropley JE, Pickett HA, Reddel RR, Suter CM (2009) Telomerase activity is associated with an increase in DNA methylation at the proximal subtelomere and a reduction in telomeric transcription. Nucleic Acids Res 37(4): 1152-1159. doi: 10. 1093/nar/gkn1030.
    • (2009) Nucleic Acids Res , vol.37 , Issue.4 , pp. 1152-1159
    • Ng, L.J.1    Cropley, J.E.2    Pickett, H.A.3    Reddel, R.R.4    Suter, C.M.5
  • 52
    • 0037154972 scopus 로고    scopus 로고
    • Epigenetic codes for heterochromatin formation and silencing: rounding up the usual suspects
    • doi:S009286740200644X
    • Richards EJ, Elgin SC (2002) Epigenetic codes for heterochromatin formation and silencing: rounding up the usual suspects. Cell 108(4): 489-500. doi: S009286740200644X.
    • (2002) Cell , vol.108 , Issue.4 , pp. 489-500
    • Richards, E.J.1    Elgin, S.C.2
  • 53
    • 0032191281 scopus 로고    scopus 로고
    • Developmental control of telomere lengths and telomerase activity in plants
    • Riha K, Fajkus J, Siroky J, Vyskot B (1998) Developmental control of telomere lengths and telomerase activity in plants. Plant Cell 10(10): 1691-1698.
    • (1998) Plant Cell , vol.10 , Issue.10 , pp. 1691-1698
    • Riha, K.1    Fajkus, J.2    Siroky, J.3    Vyskot, B.4
  • 54
    • 40949100959 scopus 로고    scopus 로고
    • Role of alternative telomere lengthening unmasked in telomerase knock-out mutant plants
    • doi:10.1007/s11103-008-9295-7
    • Ruckova E, Friml J, Prochazkova Schrumpfova P, Fajkus J (2008) Role of alternative telomere lengthening unmasked in telomerase knock-out mutant plants. Plant Mol Biol 66(6): 637-646. doi: 10. 1007/s11103-008-9295-7.
    • (2008) Plant Mol Biol , vol.66 , Issue.6 , pp. 637-646
    • Ruckova, E.1    Friml, J.2    Prochazkova Schrumpfova, P.3    Fajkus, J.4
  • 55
    • 79952994513 scopus 로고
    • S-adenosyl-L-homcysteine hydrolase from Nicotiana tabacum L.: isolation and properties
    • Šebestová L, Votruba I, Holy A (1984) S-adenosyl-L-homcysteine hydrolase from Nicotiana tabacum L.: isolation and properties. Collect Czech Chem Commun 49: 1543-1551.
    • (1984) Collect Czech Chem Commun , vol.49 , pp. 1543-1551
    • Šebestová, L.1    Votruba, I.2    Holy, A.3
  • 56
    • 77955845914 scopus 로고    scopus 로고
    • Telomeres and telomerase in normal and cancer stem cells
    • doi:10.1016/j.febslet.2010.05.026
    • Shay JW, Wright WE (2010) Telomeres and telomerase in normal and cancer stem cells. Febs Lett 584(17): 3819-3825. doi: 10. 1016/j. febslet. 2010. 05. 026.
    • (2010) Febs Lett , vol.584 , Issue.17 , pp. 3819-3825
    • Shay, J.W.1    Wright, W.E.2
  • 57
    • 34848903233 scopus 로고    scopus 로고
    • Role of histone and DNA methylation in gene regulation
    • doi:10.1016/j.pbi.2007.06.008
    • Vaillant I, Paszkowski J (2007) Role of histone and DNA methylation in gene regulation. Curr Opin Plant Biol 10(5): 528-533. doi: 10. 1016/j. pbi. 2007. 06. 008.
    • (2007) Curr Opin Plant Biol , vol.10 , Issue.5 , pp. 528-533
    • Vaillant, I.1    Paszkowski, J.2
  • 59
    • 0021111539 scopus 로고
    • Cloning of the MspI modification enzyme. The site of modification and its effects on cleavage by MspI and HpaII
    • Walder RY, Langtimm CJ, Chatterjee R, Walder JA (1983) Cloning of the MspI modification enzyme. The site of modification and its effects on cleavage by MspI and HpaII. J Biol Chem 258(2): 1235-1241.
    • (1983) J Biol Chem , vol.258 , Issue.2 , pp. 1235-1241
    • Walder, R.Y.1    Langtimm, C.J.2    Chatterjee, R.3    Walder, J.A.4
  • 60
    • 0020663387 scopus 로고
    • Effect of several antiviral agents on human lymphocyte functions and marrow progenitor cell proliferation
    • Wingard JR, Hess AD, Stuart RK, Saral R, Burns WH (1983) Effect of several antiviral agents on human lymphocyte functions and marrow progenitor cell proliferation. Antimicrob Agents Chemother 23(4): 593-597.
    • (1983) Antimicrob Agents Chemother , vol.23 , Issue.4 , pp. 593-597
    • Wingard, J.R.1    Hess, A.D.2    Stuart, R.K.3    Saral, R.4    Burns, W.H.5
  • 61
    • 21644450310 scopus 로고    scopus 로고
    • Perturbation of NgTRF1 expression induces apoptosis-like cell death in tobacco BY-2 cells and implicates NgTRF1 in the control of telomere length and stability
    • doi:10.1105/tpc.104.026278
    • Yang SW, Kim SK, Kim WT (2004) Perturbation of NgTRF1 expression induces apoptosis-like cell death in tobacco BY-2 cells and implicates NgTRF1 in the control of telomere length and stability. Plant Cell 16(12): 3370-3385. doi: 10. 1105/tpc. 104. 026278.
    • (2004) Plant Cell , vol.16 , Issue.12 , pp. 3370-3385
    • Yang, S.W.1    Kim, S.K.2    Kim, W.T.3
  • 62
    • 10644256532 scopus 로고    scopus 로고
    • Zebularine: a new drug for epigenetic therapy
    • doi:10.1042/BST0320910
    • Yoo CB, Cheng JC, Jones PA (2004) Zebularine: a new drug for epigenetic therapy. Biochem Soc Trans 32(Pt 6): 910-912. doi: 10. 1042/BST0320910.
    • (2004) Biochem Soc Trans , vol.32 , Issue.Pt 6 , pp. 910-912
    • Yoo, C.B.1    Cheng, J.C.2    Jones, P.A.3
  • 63
    • 76549102018 scopus 로고    scopus 로고
    • DNA cytosine methylation in plant development
    • doi:10.1016/S1673-8527(09)60020-5
    • Zhang M, Kimatu JN, Xu K, Liu B (2010) DNA cytosine methylation in plant development. J Genet Genomics 37(1): 1-12. doi: 10. 1016/S1673-8527(09)60020-5.
    • (2010) J Genet Genomics , vol.37 , Issue.1 , pp. 1-12
    • Zhang, M.1    Kimatu, J.N.2    Xu, K.3    Liu, B.4


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