Genomic profiling in Down syndrome acute lymphoblastic leukemia identifies histone gene deletions associated with altered methylation profiles

Leukemia

Volumn 25, Issue 10, 2011, Pages 1555-1563

  Loudin, M G ^a   Wang, J ^b   Eastwood Leung, H C ^a   Gurusiddappa, S ^a   Meyer, J ^b   Condos, G ^b   Morrison, D ^b   Tsimelzon, A ^a   Devidas, M ^c   Heerema, N A ^d   Carroll, A J ^e   Plon, S E ^a   Hunger, S P ^f   Basso, G ^g   Pession, A ^h   Bhojwani, D ⁱ   Carroll, W L ^b   Rabin, K R ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^d OHIO STATE UNIVERSITY   (United States)

^e UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^f UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^g UNIVERSITY HOSPITAL OF PADOVA   (Italy)

^h UNIVERSITY OF BOLOGNA   (Italy)

ⁱ ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

acute lymphoblastic leukemia; CRLF2; Down syndrome; histone; JAK2

Indexed keywords

HISTONE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; COPY NUMBER VARIATION; DOWN SYNDROME; GENE CLUSTER; GENE DELETION; GENE EXPRESSION PROFILING; GENE LOCUS; GENE MUTATION; GENE OVEREXPRESSION; GENETIC HETEROGENEITY; HETEROZYGOSITY LOSS; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; METHYLATION; PRIORITY JOURNAL; PROMOTER REGION; SIGNAL TRANSDUCTION;

EID: 80054047151     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2011.128     Document Type: Article

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