Clavulanic acid increases dopamine release in neuronal cells through a mechanism involving enhanced vesicle trafficking

Neuroscience Letters

Volumn 504, Issue 2, 2011, Pages 170-175

  Kost, Gina Chun ^a   Selvaraj, Senthil ^b   Lee, Young Bok ^a   Kim, Deog Joong ^a   Ahn, Chang Ho ^a   Singh, Brij B ^b  

^a Rexahn Pharmaceuticals Inc   (United States)

^b UNIVERSITY OF NORTH DAKOTA SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

Author keywords

Clavulanic acid; Depression; Dopamine; Neurotransmitter release; Rab4 Munc18 1

Indexed keywords

CLAVULANIC ACID; DOPAMINE; MUNC18 PROTEIN; RAB PROTEIN; SNARE PROTEIN; SYNTAXIN 1;

ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL MEMBRANE; CELL MIGRATION; CELL VACUOLE; CYTOPLASM; DOPAMINE METABOLISM; DOPAMINE RELEASE; DOPAMINERGIC NERVE CELL; DRUG EFFECT; DRUG MECHANISM; HUMAN; HUMAN CELL; NERVE CELL; NEUROSECRETION; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; RAT; SYNAPSE VESICLE;

ANIMALS; ANTI-BACTERIAL AGENTS; BLOOD-BRAIN BARRIER; CELL LINE; CELL LINE, TUMOR; CELL MEMBRANE; CLAVULANIC ACID; CYTOPLASM; DOPAMINE; EXOCYTOSIS; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MUNC18 PROTEINS; NEURONS; PC12 CELLS; PROTEIN BINDING; RAB GTP-BINDING PROTEINS; RATS; SYNAPTIC VESICLES;

EID: 80053939592     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2011.09.032     Document Type: Article

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