Identification of a natural compound by cell-based screening that enhances interferon regulatory factor-1 activity and causes tumor suppression

Molecular Cancer Therapeutics

Volumn 10, Issue 10, 2011, Pages 1774-1783

  Gao, Jinbo ^a   Wang, Yujun ^b   Xing, Quanhua ^b   Yan, Jin ^b   Senthil, Maheswari ^c   Akmal, Yasir ^b   Kowolik, Claudia M ^b   Kang, Julia ^b   Lu, David M ^b   Zhao, Ming ^d   Lin, Zhixiu ^d   Cheng, Christopher H K ^d   Yip, M L Richard ^b   Yim, John H ^b  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^c LOMA LINDA UNIVERSITY   (United States)

^d CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; BAICALEIN; CYCLIN D1; GENISTEIN; INTERFERON REGULATORY FACTOR 1; PUMA PROTEIN; SHORT HAIRPIN RNA;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER INHIBITION; CELL ASSAY; CONTROLLED STUDY; DRUG SCREENING; DRUG TOXICITY; FEMALE; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; MODULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; REPORTER GENE; TRANSGENIC MOUSE; TUMOR GROWTH;

ANIMALS; CELL GROWTH PROCESSES; CELL LINE, TUMOR; DISEASE MODELS, ANIMAL; FEMALE; FLAVANONES; HUMANS; INTERFERON REGULATORY FACTOR-1; MICE; MICE, SCID; NEOPLASMS; RANDOM ALLOCATION; TRANSCRIPTION FACTORS; TRANSFECTION; UP-REGULATION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 80053931866     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-11-0304     Document Type: Article

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