Aging-related regulation of myo-inositol 1,4,5-trisphosphate signal transduction pathway in the rat striatum

Molecular Brain Research

Volumn 46, Issue 1-2, 1997, Pages 39-53

  Igwe, Orisa J ^a,b   Filla, Michael B ^a  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

^b UNIVERSITY OF MISSOURI KANSAS CITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aging; Inositol 1,4,5 trisphosphate; Inositol 1,4,5 trisphosphate 3 kinase; Inositol 1,4,5 trisphosphate 5 phosphatase; Inositol 1,4,5 trisphosphate receptor; Inositol 1,4,5 trisphosphate receptor mRNA; Phosphatidylinositide; Striatum

Indexed keywords

1 AMINO 1,3 CYCLOPENTANEDICARBOXYLIC ACID; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMINO ACID RECEPTOR STIMULATING AGENT; BRAIN PROTEIN; CALCIUM ION; CALPASTATIN; CARBACHOL; INOSITOL 1,4,5 TRISPHOSPHATE; INOSITOL 1,4,5 TRISPHOSPHATE 5 PHOSPHATASE; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; INOSITOL TRISPHOSPHATE 3 KINASE; MESSENGER RNA; METABOTROPIC RECEPTOR; MUSCARINIC AGENT; PHOSPHATIDYLINOSITIDE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE;

AGING; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BRAIN FUNCTION; BRAIN NERVE CELL; BRAIN SLICE; CONTROLLED STUDY; CORPUS STRIATUM; DRUG HYDROLYSIS; ENZYME ACTIVITY; GENETIC TRANSCRIPTION; ISOTOPE LABELING; MALE; MEMBRANE REACTOR; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; RECEPTOR DENSITY; SIGNAL TRANSDUCTION;

AGING; ANIMALS; BLOTTING, NORTHERN; CALCIUM CHANNELS; CORPUS STRIATUM; HYDROLYSIS; IMMUNOBLOTTING; INOSITOL 1,4,5-TRISPHOSPHATE; MALE; RATS; RATS, INBRED F344; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 0030911647     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(96)00269-0     Document Type: Article

References (84)

1. Barritt, G.J., Intracellular free calcium and inositol polyphosphate action as potential target in the aging process, Neurobiol. Aging, 8 (1987) 359-361.
2. Batty, I.R., Nahorski, S.R. and Irvine, R.F., Rapid formation of inositol 1,3,4,5-tetrakisphosphate following muscarinic receptor stimulation of rat cerebral cortex slices, Biochem. J., 232 (1985) 211-215.
3. Berridge, M.J., Inositol trisphosphate and calcium signalling, Nature, 361 (1993) 315-325.
4. Bredt, D.S., Mourey, R.J. and Snyder, S.H., A simple, sensitive, and specific radioreceptor assay for inositol 1,4,5-trisphosphate in biological tissues, Biochem. Biophys. Res. Commun., 159 (1989) 976-982.
5. + and Cl-conductances, FEBS Lett., 217 (1987) 247-252.
6. Chomczynski, P. and Sacchi, N., Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction, Anal. Biochem., 162 (1987) 156-159.
7. Connolly, T.M., Bross, T.E. and Majerus, P.W., Isolation of a phosphomonoesterase from human platelets that specifically hydrolyzes the 5-phosphate of inositol 1,4,5-trisphosphate, J. Biol. Chem., 260 (1985) 7868-7874.
8. Croall, D.E. and DeMartino, G.N., Calcium-activated neutral protease (calpain) system: structure, function, and regulation, Physiol. Rev., 71 (1991) 813-847.
9. 2+ into hippocampal slices, J. Neurosci., 48 (1987) 1917-1924.
10. Danner, D.B. and Holbrook, N.J., Alterations in gene expression with aging. In Handbook of the Biology of Aging, 3rd edn., Academic Press, New York, NY, 1990, pp. 97-117.
11. Danoff, K.S. and Ross, C.A., The inositol trisphosphate receptor gene family: implications for normal and abnormal brain function, Prog. Neuro-Psycho. Pharmacol. Biol. Psychiatry, 18 (1994) 1-16.
12. Dean, M.N. and Beavan, M.A., Methods for the analysis of inositol phosphates, Anal. Biochem., 183 (1989) 199-209.
13. DeLeeuw, W., Slagboom, P. and Vijg, J., Quantitative comparison of mRNA levels in mammalian tissues: 28s ribosomal RNA level as an accurate internal control, Nucleic Acid Res., 17 (1989) 10137-10138.
14. 2+ activates phospholipase C, Trends Neurosci., 11 (1988) 517-520.
15. Erneux, C. and Takazawa, K., Intracellular control of inositol phosphates by their metabolising enzymes, Trends Pharmacol. Sci., 12 (1991) 174-176.
16. Ferris, C.D. and Huganir, R.L., Supattapone, S. and Snyder, S.H., Purified inositol 1,4,5-trisphosphate receptor mediates calcium influx in reconstituted lipid vesicles, Nature, 342 (1989) 87-89.
17. Fotuhi, M., Dawson, T.M., Sharp, A.M., Martin, L.J., Graybiel, A.M. and Snyder, S.H., Phosphoinositide second messenger system is enriched in striosomes: immunohistochemical demonstration of inositol 1,4,5-trisphosphate receptors and phospholipase C β and γ in primate basal ganglia, J. Neurosci., 13 (1993) 3300-3308.
18. Fulop, T. and Seres, I., Age-related changes in signal transduction, Drugs Aging, 5 (1994) 366-390.
19. 400, Nature, 342 (1989) 32-38.
20. Gibson, G.E. and Peterson, C., Calcium and the aging nervous system, Neurobiol. Aging, 8 (1987) 329-343.
21. Graybiel, A.M. and Ragsdale Jr., C.W., Biochemical anatomy of the stratum. In Chemical Neuroanatomy, Raven Press, New York, NY, 1983, pp. 427-504.
22. Harlow, E. and Lane, D., Antibody-antigen interactions. In Antibodies: A Laboratory Manual, Cold Spring Harbor Laboratory Publication, Cold Spring Harbor, NY, 1988, pp. 23-35.
23. Hartmann, H., Eckert, A. and Muller, W.E., Aging enhances the calcium sensitivity of central neurons of the mouse as an adaptive response to reduced free intracellular calcium, Neurosci. Lett., 152 (1993) 181-184.
24. Hartmann, H. and Muller, W.E., Age-related changes in receptor-mediated and depolarization-induced phosphatidylinositol turnover in mouse brain, Brain Res., 622 (1992) 86-92.
25. Hilly, M., Pietri-Rouxel, F., Coquil, J.F., Guy, M. and Mauger, J.-P., Thiol reagents increase the affinity of the inositol 1,4,5-trisphosphate receptor, J. Biol. Chem., 268 (1993) 16488-16494.
26. Igwe, O.J., Regulation of substance P receptor system in rat striatum by chronic naltrexone treatment, Mol. Brain Res., 20 (1993) 40-50.
27. Igwe, O.J. and Ning, L., Inositol 1,4,5-trisphosphate arm of the phosphatidylinositide signal transduction pathway in the rat cerebellum during aging, Neurosci. Lett., 164 (1993) 167-170.
28. Jolles, J., Bothmer, J., Markerink, M. and Ravid, R., Phosphatidylinositol kinase is reduced in Alzheimer's disease, J. Neurochem., 58 (1992) 2326-2329.
29. Joseph, J.A., Gupta, M., Han, Z. and Roth, G.S., The deleterious effects of aging and kainic acid may be selective for similar striatal populations, Aging, 3 (1991) 361-371.
30. Joseph, J.A., Kowatch, M.A., Maki, T. and Roth, G.S., Selective cross-activation/inhibition of second messenger systems and the reduction of age-related deficits in the muscarinic control of dopamine release from perfused rat striata, Brain Res., 537 (1990) 40-48.
31. Joseph, J.A., Roth, G.S. and Strong, S., The striatum, a microcosm for the examination of age-related alterations in the CNS: a selected review, Rev. Biol. Res. Aging, 4 (1990) 181-191.
32. Joseph, S.K. and Ryan, S.V., Phosphorylation of the inositol trisphosphate receptor in isolated hepatocytes, J. Biol. Chem., 268 (1993) 23059-23065.
33. Kohno, A., Cinader, B. and Seeman, P., Age-related changes of beta-adrenoceptors in spleen lymphocytes and cerebral cortex of NZB/BIN mice, Immunol. Lett., 14 (1986) 75-78.
34. Kötter, R., Postsynaptic integration of glutaminergic and dopaminergic signals in the striatum, Prog. Neurobiol., 44 (1994) 164-196.
35. 4, Nature, 227 (1970) 680-685.
36. Lee, S.Y., Sims, S.S., Kim, J.W., Moon, K.H., Kim, J.H. and Rhee, S.G., Purification and properties of D-myo-inositol 1,4,5-trisphosphate 3-kinase from rat brain, J. Biol. Chem., 265 (1990) 9434-9440.
37. Lin, T.-A., Lin, T.N., He, Y.Y., Hsu, C.Y. and Sun, G.Y., Effects of focal cerebral ischemia on inositol 1,4,5-trisphosphate 3-kinase and 5-phosphatase activities in rat cortex, Biochem. Biophys. Res. Commun., 184 (1992) 871-877.
38. 2+ channel, FEBS Lett., 323 (1993) 229-232.
39. Martinez, A., Vitorica, J. and Satrustegui, J., Differential effects of age on the pathways of calcium influx into nerve terminals, Neurosci. Lett., 88 (1988) 336-342.
40. Martinez-Serrano, A., Blanco, P. and Satrystegui, J., Calcium binding to cytosol and calcium extrusion mechanisms in intact synaptosomes and their alterations with aging, J. Biol. Chem., 267 (1992) 4672-4679.
41. Manzoni, O., Prezeau, L., Rassendren, F.A., Sladeczek, F., Curry, K. and Bockaert, J., Both enatiomers of 1-aminocyclopentyl-1,3-di-carboxylate are full agonists of metabotropic glutamate receptors coupled to phospholipase C, Mol. Pharmacol., 42 (1992) 322-327.
42. McPherson, G.A., A practical computer-based approach to the analysis of radioligand and binding experiments, Comput. Programs Biomed., 17 (1983) 107-114.
43. Melloni, E. and Pontremoli, S., The calpains, Trends Neurosci., 12 (1989) 438-444.
44. Mignery, G.A., Newton, C.L., Archer, B.T. and Südhoff, T.C., Structure and expression of rat inositol 1,4,5-trisphosphate receptor, J. Biol. Chem., 265 (1990) 12679-12685.
45. 2+ leak in permeabilized A7R5 cells, Biochem. Biophys. Res. Commun., 193 (1993) 6-12.
46. Mundy, W., Tandon, P., Ali, S. and Tilson, H., Age-related changes in receptor-mediated phosphoinositide hydrolysis in various regions of rat brain, Life Sci., 49 (1991) PL97-PL102.
47. Munson, P.J. and Rodbard, D., LIGAND: a versatile computerized approach for the characterization of ligand binding systems, Anal. Biochem., 107 (1980) 220-239.
48. Murphy, T.H., Wright, D.D. and Baraban, J.M., Phosphoinositide turnover is associated with synaptic transmission, J. Neurochem., 59 (1992) 2336-2339.
49. Nahorski, S.R. and Potter, B.V.L., Molecular recognition of inositol polyphosphates by intracellular receptors and metabolic inhibitors, Trends Pharmacol. Sci., 10 (1989) 139-144.
50. Nalepa, I., Pintor, A., Fortuna, S., Vetulani, J. and Michalek, H., Increased responsiveness of the cerebral cortical phosphatidylinositol system to noradrenaline and carbichol in senescent rats, Neurosci. Lett., 107 (1989) 195-199.
51. 3, J. Biol. Chem., 269 (1994) 28613-28619.
52. Nishino, N., Kitamura, N., Hashimoto, T. and Tanaka, T., Phorbol ester binding sites in human brain: characterization, regional distribution, age-correlation, and alterations in Parkinson's disease, J. Mol. Neurosci., 1 (1989) 19-26.
53. Paxinos, G. and Watson, C., In The Rat Brain in Stereotaxic Coordinates, 2nd edn., Academic Press, New York, NY, 1986.
54. 3H]MK-801 binding to the NMDA receptor complex, and its modulation in human frontal cortex during development and aging, Brain Res., 588 (1992) 277-286.
55. Pizzi, M., Fallacara, C., Arrighi, V., Memo, M. and Spano, P.F., Attenuation of excitatory aminoacid toxicity by metabotropic glutamate receptor agonists and aniracetam in primary cultures of cerebellar granule cells, J. Neurochem., 61 (1993) 683-689.
56. Ross, C.A., Danoff, S.K., Schell, M.J., Snyder, S.H. and Ullrich, A., Three additional inositol 1,4,5-trisphosphate receptors. Molecular cloning and differential localization in brain and peripheral tissue, Proc. Natl. Acad. Sci. USA, 89 (1992) 4265-4269.
57. Roth, G.S., Mechanisms of altered hormone-neurotransmitter action during aging: from receptor to calcium mobilization, Annu. Rev. Geront. Geriatr., 10 (1990) 132-146.
58. Sabol, K.E., Neill, D.B., Wages, S.A., Church, W.H. and Justice, J.B., Dopamine depletion in a striatal subregion disrupts performance of a skilled motor task in the rat, Brain Res., 335 (1985) 33-43.
59. Sasaki, T., Kishi, M., Saito, M., Tanaka, T., Higuchi, N., Kominami, E., Katunuma, N. and Murachi, T., Inhibitory effect of di- and tripeptidyl aldehydes on calpains and cathepsins, J. Enzyme Inhibition, 3 (1990) 195-201.
60. Sato, R., Bock, G. and Widdows, K., In Interactions Among Cell Signalling Systems. Ciba Foundation Symposium 164, John Wiley and Sons, Chichester, NY, 1992.
61. Schoepp, D.D. and Hillman, Jr., C.C., Developmental and pharmacological characterization of quisqulate, ibotenate, and trans-1-aminocyclopentane dicarboxylic acid stimulation of phosphoinositide hydrolysis in rat cortical brain slices, Biogenic Amines, 7 (1990) 331-340.
62. Sim, S.S., Kim, J.W. and Rhee, S.G., Regulation of D-myo-inositol 1,4,5-trisphosphate 3-kinase by cAMP-dependent protein kinase and protein kinase C, J. Biol. Chem., 265 (1990) 10367-10372.
63. Simpson, P.B., Challis, R.A.J. and Nahorski, S.R., Chronic activation of muscarinic and metabotropic glutamate receptors down regulates type 1 inositol 1,4,5-trisphosphate receptor expression in cerebellar granule cells, J. Neurochem., 63 (1994) 2369-2372.
64. Smith, P.K., Krohn, R.I., Hermanson, G.T., Mallia, A.K., Gartner, F.A., Provenzano, M.D., Fujimoto, E.K., Goeke, N.M., Olson, B.J. and Klenk, D.C., Measurement of protein using bicicinchoninic acid, Anal. Biochem., 150 (1985) 76-85.
65. Spanakis, E., Problems related to the interpretation of autoradiographic data on gene expression using common constitutive transcripts as control, Nucleic Acids Res., 16 (1993) 3809-3819.
66. Stadtman, E.R., Protein oxidation and aging, Science, 257 (1992) 1220-1224.
67. Stokes, C.E., Gillon, K.R. and Hawthorne, J.N., Free and total lipid myo-inositol concentrations decrease with age in human brains, Biochim. Biophys. Acta, 753 (1983) 136-138.
68. Strosznajder, J., Samochocki, M., Wikiel, H. and Malecki, A., Aging modulates calcium-dependent phosphatidylinositol degradation by cerebral cortex synaptic plasma membrane phospholipases, Mol. Chem. Neuropathol., 21 (1994) 95-107.
69. Sugawa, M., Alterations of inositol phosphate turnover in striatum of aged rats, Eur. J. Pharmacol., 247 (1993) 39-44.
70. Supattapone, S., Worley, P.F., Baraban, J.M. and Snyder, S.H., Solubilization, purification and characterization of inositol trisphosphate receptor, J. Biol. Chem., 263 (1988) 1530-1534.
71. Surichamorn, W., Abdallah, E.A.M. and El-Fakahany, E.E., Aging does not alter brain muscarinic receptor mediated phosphoinositide hydrolysis and its inhibition by phorbol esters, tetrodotoxin and receptor desensitization, J. Pharmacol. Exp. Ther., 251 (1989) 543-549.
72. Towbin H., Staehelin, T. and Bordon, J., Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedures and applications, Proc. Natl. Acad. Sci. USA, 76 (1989) 4350-4354.
73. Undie, A.S., Wang, H.-Y. and Friedman, E., Decreased phospholipase C-β immunoreactivity, phosphoinositide metabolism, and protein kinase C activation in senescent F-344 rat brain, Neurobiol. Aging, 16 (1995) 19-28.
74. Verhage, M., McMahon, H.T., Ghijsen, W.E., Boomsma, F., Scholten, G., Wiegant, V.M. and Nichols, D.G., Differential release of amino acids neuropeptides, and catecholamines from isolated nerve terminals, Neuron, 6 (1991) 517-524.
75. Wang, K.K.W, and Yuen, P.-W., Calpain inhibition: an overview of its therapeutic potential, Trend Pharmacol. Sci., 15 (1994) 412-419.
76. 2+-dependent neutral protease, Arch. Biochem. Biophys., 260 (1988) 696-704.
77. 3H]inositol 1,4,5-trisphosphate binding in Huntington's disease, J. Neurochem., 56 (1990) 1417-1422.
78. Weiss, S., Pin, J.P., Sebben, M., Kemp, D.E., Sladeczek, F., Gabrion, J. and Bockaert, J., Synaptogenesis of cultured striatal neurons in serum-free medium: a morphological and biochemical study, Proc. Natl. Acad. Sci. USA, 83 (1986) 2238-2242.
79. Wojcikiewicz, R.J.H., Type I, II and III inositol 1,4,5-trisphosphate receptors are unequally susceptible to down regulation and are expressed in markedly different proportions in different cell types, J. Biol. Chem., 270 (1995) 11678-11683.
80. Wojcikiewicz, R.J.H., Furuichi, S., Nakade, S., Mikoshiba, K. and Nahorski, S.R., Muscarinic receptor activation down-regulates the type 1 inositol 1,4,5-trisphosphate receptor by accelerating its degradation, J. Biol. Chem., 269 (1994) 7963-7969.
81. Wojcikiewicz, R.J.H. and Nahorski, S.R., Modulation of signalling initiated by phosphoinositidase C-linked receptors, J. Exp. Biol., 184 (1993) 145-159.
82. Wreggett, K.A. and Irvine, R.F., A rapid separation method for inositol phosphates and their isomers, Biochem. J., 245 (1987) 655-660.
83. 3H]inositol 1,4,5-trisphosphate binding in Alzheimer's disease, Neurosci. Lett., 94 (1988) 198-202.
84. 2 receptor mRNA-containing neurons: a quantitative nonradioactive in situ hybridization study, J. Neurosci., 15 (1995) 1735-1740.