Iron insufficiency compromises motor neurons and their mitochondrial function in Irp2-null mice

PLoS ONE

Volumn 6, Issue 10, 2011, Pages

  Jeong, Suh Young ^a   Crooks, Daniel R ^a   Wilson Ollivierre, Hayden ^a   Ghosh, Manik C ^a   Sougrat, Rachid ^b   Lee, Jaekwon ^c   Cooperman, Sharon ^a   Mitchell, James B ^d   Beaumont, Carole ^e   Rouault, Tracey A ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Saudi Arabia)

^c UNIVERSITY OF NEBRASKA LINCOLN   (United States)

^d NATIONAL CANCER INSTITUTE   (United States)

^e CENTRE DE RECHERCHE BIOMÉDICALE BICHAT BEAUJON CRB3   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD71 ANTIGEN; FERRITIN; IRON; IRON REGULATORY PROTEIN 1; IRON REGULATORY PROTEIN 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE); AMINE OXIDE; APOFERRITIN; BIOLOGICAL MARKER; TEMPOL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL FUNCTION; CELL LYSATE; CONTROLLED STUDY; DNA MODIFICATION; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; HOMEOSTASIS; IMMUNOHISTOCHEMISTRY; IRON DEFICIENCY; IRON STORAGE; LUMBAR SPINAL CORD; MITOCHONDRION; MOTONEURON; MOUSE; NERVE CELL DEGENERATION; NERVE FIBER DEGENERATION; NEUROPATHY; NONHUMAN; PROTEIN SYNTHESIS; ANIMAL; ATROPHY; BIOSYNTHESIS; BRAIN; DRUG EFFECT; GENE DELETION; GENETICS; METABOLISM; NERVE FIBER; OXIDATIVE STRESS; PATHOLOGY; SPIN LABELING; SPINAL CORD;

MUS;

ANIMALS; APOFERRITINS; ATROPHY; AXONS; BIOLOGICAL MARKERS; BRAIN; CYCLIC N-OXIDES; GENE DELETION; HOMEOSTASIS; IRON; IRON REGULATORY PROTEIN 1; IRON REGULATORY PROTEIN 2; MICE; MITOCHONDRIA; MOTOR NEURONS; OXIDATIVE STRESS; SPIN LABELS; SPINAL CORD;

EID: 80053902000     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0025404     Document Type: Article

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