메뉴 건너뛰기




Volumn 296, Issue 2, 2009, Pages

Deletion of hepatic Ctrl reveals its function in copper acquisition and compensatory mechanisms for copper homeostasis

Author keywords

Bile; Copper excretion; Cuproenzymes; Liver specific copper transporter 1 deletion; Urine

Indexed keywords

COPPER; COPPER ZINC SUPEROXIDE DISMUTASE; CYTOCHROME C OXIDASE; IRON; MENKES PROTEIN; MENKES PROTEIN 1; UNCLASSIFIED DRUG; ZINC; CATION TRANSPORT PROTEIN; CERULOPLASMIN; CTR1 PROTEIN, MOUSE; SUPEROXIDE DISMUTASE;

EID: 59449094867     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.90632.2008     Document Type: Article
Times cited : (79)

References (52)
  • 1
    • 38949145276 scopus 로고    scopus 로고
    • Ctr2 is partially localized to the plasma membrane and stimulates copper uptake in COS-7 cells
    • Bertinato J, Swist E, Plouffe LJ, Brooks SP, L'abbé MR. Ctr2 is partially localized to the plasma membrane and stimulates copper uptake in COS-7 cells. Biochem J 409: 731-740, 2008.
    • (2008) Biochem J , vol.409 , pp. 731-740
    • Bertinato, J.1    Swist, E.2    Plouffe, L.J.3    Brooks, S.P.4    L'abbé, M.R.5
  • 2
    • 0034845675 scopus 로고    scopus 로고
    • Brewer GJ. Zinc acetate for the treatment of Wilson's disease. Expert Opin Pharmacother 2: 1473-1477, 001.
    • Brewer GJ. Zinc acetate for the treatment of Wilson's disease. Expert Opin Pharmacother 2: 1473-1477, 001.
  • 3
    • 0034937998 scopus 로고    scopus 로고
    • Copper control as an antiangiogenic anticancer therapy: Lessons from treating Wilson's disease
    • Brewer GJ. Copper control as an antiangiogenic anticancer therapy: lessons from treating Wilson's disease. Exp Biol Med (Maywood) 226: 665-673, 2001.
    • (2001) Exp Biol Med (Maywood) , vol.226 , pp. 665-673
    • Brewer, G.J.1
  • 4
    • 0028853625 scopus 로고
    • Mammalian cytochrome-c oxidase: Characterization of enzyme and immunological detection of subunits in tissue extracts and whole cells
    • Capaldi RA, Marusich MF, Taanman JW. Mammalian cytochrome-c oxidase: characterization of enzyme and immunological detection of subunits in tissue extracts and whole cells. Methods Enzymol 260: 117-132, 1995.
    • (1995) Methods Enzymol , vol.260 , pp. 117-132
    • Capaldi, R.A.1    Marusich, M.F.2    Taanman, J.W.3
  • 5
    • 33746929896 scopus 로고    scopus 로고
    • Copper trafficking to the mitochondrion and assembly of copper metalloenzymes
    • Cobine PA, Pierrel F, Winge DR. Copper trafficking to the mitochondrion and assembly of copper metalloenzymes. Biochim Biophys Acta 1763: 759-772, 2006.
    • (2006) Biochim Biophys Acta , vol.1763 , pp. 759-772
    • Cobine, P.A.1    Pierrel, F.2    Winge, D.R.3
  • 7
    • 0028010889 scopus 로고
    • Molecular characterization of a copper transport protein in S. cerevisiae: An unexpected role for copper in iron transport
    • Dancis A, Yuan DS, Haile D, Askwith C, Eide D, Moehle C, Kaplan J, Klausner RD. Molecular characterization of a copper transport protein in S. cerevisiae: an unexpected role for copper in iron transport. Cell 76:393-402, 1994.
    • (1994) Cell , vol.76 , pp. 393-402
    • Dancis, A.1    Yuan, D.S.2    Haile, D.3    Askwith, C.4    Eide, D.5    Moehle, C.6    Kaplan, J.7    Klausner, R.D.8
  • 9
    • 2342444345 scopus 로고    scopus 로고
    • Identification of methionine-rich clusters that regulate copper-stimulated endocytosis of the human Ctr1 copper transporter
    • Guo Y, Smith K, Lee J, Thiele DJ, Petris MJ. Identification of methionine-rich clusters that regulate copper-stimulated endocytosis of the human Ctr1 copper transporter. J Biol Chem 279: 17428-17433, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 17428-17433
    • Guo, Y.1    Smith, K.2    Lee, J.3    Thiele, D.J.4    Petris, M.J.5
  • 10
    • 34547507297 scopus 로고    scopus 로고
    • Vertebrate Ctr1 coordinates morphogenesis and progenitor cell fate and regulates embryonic stem cell differentiation
    • Haremaki T, Fraser ST, Kuo YM, Baron MH, Weinstein DC. Vertebrate Ctr1 coordinates morphogenesis and progenitor cell fate and regulates embryonic stem cell differentiation. Proc Natl Acad Sci USA 104:12029 -12034, 2007.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 12029-12034
    • Haremaki, T.1    Fraser, S.T.2    Kuo, Y.M.3    Baron, M.H.4    Weinstein, D.C.5
  • 11
    • 0032875387 scopus 로고    scopus 로고
    • Targeted gene disruption reveals an essential role for ceruloplasmin in cellular iron efflux
    • Harris ZL, Durley AP, Man TK, Gitlin JD. Targeted gene disruption reveals an essential role for ceruloplasmin in cellular iron efflux. Proc Natl Acad Sci USA 96: 10812-10817, 1999.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 10812-10817
    • Harris, Z.L.1    Durley, A.P.2    Man, T.K.3    Gitlin, J.D.4
  • 12
    • 0036400025 scopus 로고    scopus 로고
    • Ceruloplasmin metabolism and function
    • Hellman NE, Gitlin JD. Ceruloplasmin metabolism and function. Annu Rev Nutr 22: 439-458, 2002.
    • (2002) Annu Rev Nutr , vol.22 , pp. 439-458
    • Hellman, N.E.1    Gitlin, J.D.2
  • 13
    • 0034122029 scopus 로고    scopus 로고
    • Ethylene captures a metal! Metal ions are involved in ethylene perception and signal transduction
    • Hirayama T, Alonso JM. Ethylene captures a metal! Metal ions are involved in ethylene perception and signal transduction. Plant Cell Physiol 41: 548-555, 2000.
    • (2000) Plant Cell Physiol , vol.41 , pp. 548-555
    • Hirayama, T.1    Alonso, J.M.2
  • 15
    • 0032980728 scopus 로고    scopus 로고
    • Transcriptional regulation of interleukin-2 gene expression is impaired by copper deficiency in Jurkat human T lymphocytes
    • Hopkins RG, Failla ML. Transcriptional regulation of interleukin-2 gene expression is impaired by copper deficiency in Jurkat human T lymphocytes. J Nutr 129: 596-601, 1999.
    • (1999) J Nutr , vol.129 , pp. 596-601
    • Hopkins, R.G.1    Failla, M.L.2
  • 16
    • 39349112330 scopus 로고    scopus 로고
    • Mechanisms for copper acquisition, distribution and regulation
    • Kim BE, Nevitt T, Thiele DJ. Mechanisms for copper acquisition, distribution and regulation. Nat Chem Biol 4: 176 -185, 2008.
    • (2008) Nat Chem Biol , vol.4 , pp. 176-185
    • Kim, B.E.1    Nevitt, T.2    Thiele, D.J.3
  • 17
    • 0033981606 scopus 로고    scopus 로고
    • Cardiovascular disease from copper deficiency-a history
    • Klevay LM. Cardiovascular disease from copper deficiency-a history. J Nutr 130: 489S-492S, 2000.
    • (2000) J Nutr , vol.130
    • Klevay, L.M.1
  • 18
    • 31544454133 scopus 로고    scopus 로고
    • Copper transport protein (Ctr1) levels in mice are tissue specific and dependent on copper status
    • Kuo YM, Gybina AA, Pyatskowit JW, Gitschier J, Prohaska JR. Copper transport protein (Ctr1) levels in mice are tissue specific and dependent on copper status. J Nutr 136: 21-26, 2006.
    • (2006) J Nutr , vol.136 , pp. 21-26
    • Kuo, Y.M.1    Gybina, A.A.2    Pyatskowit, J.W.3    Gitschier, J.4    Prohaska, J.R.5
  • 19
    • 0035811069 scopus 로고    scopus 로고
    • The copper transporter CTR1 provides an essential function in mammalian embryonic development
    • Kuo YM, Zhou B, Cosco D, Gitschier J. The copper transporter CTR1 provides an essential function in mammalian embryonic development. Proc Natl Acad Sci USA 98: 6836-6841, 2001.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 6836-6841
    • Kuo, Y.M.1    Zhou, B.2    Cosco, D.3    Gitschier, J.4
  • 20
    • 33748913805 scopus 로고    scopus 로고
    • Molecular mechanisms of copper homeostasis in yeast
    • Lee J, Adle D, Kim H. Molecular mechanisms of copper homeostasis in yeast. Topics Curr Genet 14: 1-36, 2006.
    • (2006) Topics Curr Genet , vol.14 , pp. 1-36
    • Lee, J.1    Adle, D.2    Kim, H.3
  • 21
    • 0037040252 scopus 로고    scopus 로고
    • Biochemical characterization of the human copper transporter Ctr1
    • Lee J, Pena MM, Nose Y, Thiele DJ. Biochemical characterization of the human copper transporter Ctr1. J Biol Chem 277: 4380-4387, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 4380-4387
    • Lee, J.1    Pena, M.M.2    Nose, Y.3    Thiele, D.J.4
  • 22
    • 0037174814 scopus 로고    scopus 로고
    • Characterization of mouse embryonic cells deficient in the ctr1 high affinity copper transporter. Identification of a Ctr1-independent copper transport system
    • Lee J, Petris MJ, Thiele DJ. Characterization of mouse embryonic cells deficient in the ctr1 high affinity copper transporter. Identification of a Ctr1-independent copper transport system. J Biol Chem 277: 40253-40259, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 40253-40259
    • Lee, J.1    Petris, M.J.2    Thiele, D.J.3
  • 23
    • 0035811053 scopus 로고    scopus 로고
    • Essential role for mammalian copper transporter Ctr1 in copper homeostasis and embryonic development
    • Lee J, Prohaska JR, Thiele DJ. Essential role for mammalian copper transporter Ctr1 in copper homeostasis and embryonic development. Proc Natl Acad Sci USA 98: 6842-6847, 2001.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 6842-6847
    • Lee, J.1    Prohaska, J.R.2    Thiele, D.J.3
  • 24
    • 0034702881 scopus 로고    scopus 로고
    • Isolation of a murine copper transporter gene, tissue specific expression and functional complementation of a yeast copper transport mutant
    • Lee J, Prohaska JR, Dagenais SL, Glover TW, Thiele DJ. Isolation of a murine copper transporter gene, tissue specific expression and functional complementation of a yeast copper transport mutant. Gene 254: 87-96, 2000.
    • (2000) Gene , vol.254 , pp. 87-96
    • Lee, J.1    Prohaska, J.R.2    Dagenais, S.L.3    Glover, T.W.4    Thiele, D.J.5
  • 28
    • 34447510930 scopus 로고    scopus 로고
    • Function and regulation of human copper-transporting ATPases
    • Lutsenko S, Barnes NL, Bartee MY, Dmitriev OY. Function and regulation of human copper-transporting ATPases. Physiol Rev 87: 1011-1046, 2007.
    • (2007) Physiol Rev , vol.87 , pp. 1011-1046
    • Lutsenko, S.1    Barnes, N.L.2    Bartee, M.Y.3    Dmitriev, O.Y.4
  • 29
    • 0035965212 scopus 로고    scopus 로고
    • Copper transport and metabolism are normal in aceruloplasminemic mice
    • Meyer LA, Durley AP, Prohaska JR, Harris ZL. Copper transport and metabolism are normal in aceruloplasminemic mice. J Biol Chem 276: 36857-36861, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 36857-36861
    • Meyer, L.A.1    Durley, A.P.2    Prohaska, J.R.3    Harris, Z.L.4
  • 30
    • 0027368497 scopus 로고
    • Spectrophotometric assay of superoxide dismutase activity based on the activated autoxidation of a tetracyclic catechol
    • Nebot C, Moutet M, Huet P, Xu JZ, Yadan JC, Chaudiere J. Spectrophotometric assay of superoxide dismutase activity based on the activated autoxidation of a tetracyclic catechol. Anal Biochem 214: 442-451, 1993.
    • (1993) Anal Biochem , vol.214 , pp. 442-451
    • Nebot, C.1    Moutet, M.2    Huet, P.3    Xu, J.Z.4    Yadan, J.C.5    Chaudiere, J.6
  • 31
    • 33747849534 scopus 로고    scopus 로고
    • Ctr1 drives intestinal copper absorption and is essential for growth, iron metabolism, and neonatal cardiac function
    • Nose Y, Kim BE, Thiele DJ. Ctr1 drives intestinal copper absorption and is essential for growth, iron metabolism, and neonatal cardiac function. Cell Metab 4: 235-244, 2006.
    • (2006) Cell Metab , vol.4 , pp. 235-244
    • Nose, Y.1    Kim, B.E.2    Thiele, D.J.3
  • 32
    • 0021722482 scopus 로고
    • Reevaluation of assay methods and establishment of kit for superoxide dismutase activity
    • Oyanagui Y. Reevaluation of assay methods and establishment of kit for superoxide dismutase activity. Anal Biochem 142: 290 -296, 1984.
    • (1984) Anal Biochem , vol.142 , pp. 290-296
    • Oyanagui, Y.1
  • 34
    • 0038439210 scopus 로고    scopus 로고
    • Copper-stimulated endocytosis and degradation of the human copper transporter, hCtr1
    • Petris MJ, Smith K, Lee J, Thiele DJ. Copper-stimulated endocytosis and degradation of the human copper transporter, hCtr1. J Biol Chem 278: 9639-9646, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 9639-9646
    • Petris, M.J.1    Smith, K.2    Lee, J.3    Thiele, D.J.4
  • 35
    • 0030968487 scopus 로고    scopus 로고
    • Effect of copper on nitric oxide synthase and guanylyl cyclase activity in the rat isolated aorta
    • Plane F, Wigmore S, Angelini GD, Jeremy JY. Effect of copper on nitric oxide synthase and guanylyl cyclase activity in the rat isolated aorta. Br J Pharmacol 121: 345-350, 1997.
    • (1997) Br J Pharmacol , vol.121 , pp. 345-350
    • Plane, F.1    Wigmore, S.2    Angelini, G.D.3    Jeremy, J.Y.4
  • 36
    • 0034059141 scopus 로고    scopus 로고
    • DNA excision in liver by an albumin-Cretransgene occurs progressively with age
    • Postic C, Magnuson MA. DNA excision in liver by an albumin-Cretransgene occurs progressively with age. Genesis 26: 149 -150, 2000.
    • (2000) Genesis , vol.26 , pp. 149-150
    • Postic, C.1    Magnuson, M.A.2
  • 38
    • 0034235274 scopus 로고    scopus 로고
    • Long-term functional consequences of malnutrition during brain development: Copper
    • Prohaska JR. Long-term functional consequences of malnutrition during brain development: copper. Nutrition 16: 502-504, 2000.
    • (2000) Nutrition , vol.16 , pp. 502-504
    • Prohaska, J.R.1
  • 39
    • 0035450413 scopus 로고    scopus 로고
    • Lower copper, zinc-superoxide dismutase protein but not mRNA in organs of copper-deficient rats
    • Prohaska JR, Brokate B. Lower copper, zinc-superoxide dismutase protein but not mRNA in organs of copper-deficient rats. Arch Biochem Biophys 393: 170-176, 2001.
    • (2001) Arch Biochem Biophys , vol.393 , pp. 170-176
    • Prohaska, J.R.1    Brokate, B.2
  • 40
    • 0019796074 scopus 로고
    • Copper deficiency suppresses the immune response of mice
    • Prohaska JR, Lukasewycz OA. Copper deficiency suppresses the immune response of mice. Science 213: 559 -561, 1981.
    • (1981) Science , vol.213 , pp. 559-561
    • Prohaska, J.R.1    Lukasewycz, O.A.2
  • 41
    • 0025551226 scopus 로고
    • Effects of copper deficiency on the immune system
    • Prohaska JR, Lukasewycz OA. Effects of copper deficiency on the immune system. Adv Exp Med Biol 262: 123-143, 1990.
    • (1990) Adv Exp Med Biol , vol.262 , pp. 123-143
    • Prohaska, J.R.1    Lukasewycz, O.A.2
  • 43
    • 0031711780 scopus 로고    scopus 로고
    • Physiologic concentrations of zinc affect the kinetics of copper uptake and transport in the human intestinal cell model, Caco-2
    • Reeves PG, Briske-Anderson M, Johnson L. Physiologic concentrations of zinc affect the kinetics of copper uptake and transport in the human intestinal cell model, Caco-2. J Nutr 128: 1794-1801, 1998.
    • (1998) J Nutr , vol.128 , pp. 1794-1801
    • Reeves, P.G.1    Briske-Anderson, M.2    Johnson, L.3
  • 44
    • 0025729544 scopus 로고
    • Mechanisms of copper incorporation during the biosynthesis of human ceruloplasmin
    • Sato M, Gitlin JD. Mechanisms of copper incorporation during the biosynthesis of human ceruloplasmin. J Biol Chem 266: 5128 -5134, 1991.
    • (1991) J Biol Chem , vol.266 , pp. 5128-5134
    • Sato, M.1    Gitlin, J.D.2
  • 45
    • 33749534285 scopus 로고    scopus 로고
    • Role of the Menkes copper-transporting ATPase in NMDA receptor-mediated neuronal toxicity
    • Schlief ML, West T, Craig AM, Holtzman DM, Gitlin JD. Role of the Menkes copper-transporting ATPase in NMDA receptor-mediated neuronal toxicity. Proc Natl Acad Sci USA 103: 14919-14924, 2006.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 14919-14924
    • Schlief, M.L.1    West, T.2    Craig, A.M.3    Holtzman, D.M.4    Gitlin, J.D.5
  • 47
    • 0034951707 scopus 로고    scopus 로고
    • Cytochrome c oxidase deficiency
    • Shoubridge EA. Cytochrome c oxidase deficiency. Am J Med Genet 106: 46-52, 2001.
    • (2001) Am J Med Genet , vol.106 , pp. 46-52
    • Shoubridge, E.A.1
  • 48
    • 0038241789 scopus 로고    scopus 로고
    • Hepatic copper metabolism: Insights from genetic disease
    • Tao TY, Gitlin JD. Hepatic copper metabolism: insights from genetic disease. Hepatology 37: 1241-1247, 2003.
    • (2003) Hepatology , vol.37 , pp. 1241-1247
    • Tao, T.Y.1    Gitlin, J.D.2
  • 52
    • 0030844529 scopus 로고    scopus 로고
    • hCTR1: A human gene for copper uptake identified by complementation in yeast
    • Zhou B, Gitschier J. hCTR1: a human gene for copper uptake identified by complementation in yeast. Proc Natl Acad Sci USA 94: 7481-7486, 1997.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 7481-7486
    • Zhou, B.1    Gitschier, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.