Astragalus polysaccharides enhance the humoral and cellular immune responses of hepatitis B surface antigen vaccination through inhibiting the expression of transforming growth factor β and the frequency of regulatory T cells

FEMS Immunology and Medical Microbiology

Volumn 63, Issue 2, 2011, Pages 228-235

  Du, Xiaogang ^b   Chen, Xiaobing ^a   Zhao, Bing ^a   Lv, Yao ^a   Zhang, Huaiyu ^a   Liu, Hanmei ^a   Chen, Zhiyu ^a   Chen, Yanger ^a   Zeng, Xianyin ^a  

^a SICHUAN AGRICULTURAL UNIVERSITY   (China)

^b TUFTS UNIVERSITY   (United States)

Author keywords

Adjuvant; Astragalus polysaccharides; Hepatitis B vaccine; Immune response; TGF ; TLR 4; Treg

Indexed keywords

ASTRAGALUS POLYSACCHARIDE; BETA ACTIN; CELL PROTEIN; FAS ANTIGEN; FAS LIGAND; GAMMA INTERFERON; HEPATITIS B SURFACE ANTIGEN; HERBACEOUS AGENT; IMMUNOMODULATING AGENT; INTERLEUKIN 2; INTERLEUKIN 4; PROTEIN GRAB; RECOMBINANT HEPATITIS B VACCINE; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ANTIGEN ANTIBODY REACTION; ARTICLE; ASTRALAGUS MEMBRANACEUS; CD4+ CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CHINESE HERB; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXIC T LYMPHOCYTE; DOWN REGULATION; FEMALE; GENE EXPRESSION; HUMORAL IMMUNITY; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; UPREGULATION;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ASTRAGALUS MEMBRANACEUS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; FEMALE; GENE EXPRESSION PROFILING; HEPATITIS B ANTIBODIES; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VACCINES; INTERFERON-GAMMA; MICE; POLYSACCHARIDES; T-LYMPHOCYTES, CYTOTOXIC; T-LYMPHOCYTES, REGULATORY; TRANSFORMING GROWTH FACTORS;

EID: 80053900310     PISSN: 09288244     EISSN: 1574695X     Source Type: Journal    
DOI: 10.1111/j.1574-695X.2011.00845.x     Document Type: Article

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