Cimetidine enhances immune response of HBV DNA vaccination via impairment of the regulatory function of regulatory T cells

Biochemical and Biophysical Research Communications

Volumn 372, Issue 3, 2008, Pages 491-496

  Wang, Junpeng ^a   Su, Baowei ^a   Ding, Zheng ^a   Du, Xiaogang ^a   Wang, Bin ^a  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

Author keywords

Adjuvant; Cell mediated immunity; Cimetidine; DTH; HBV DNA vaccine; In vivo cytotoxic; Regulatory T cell

Indexed keywords

CIMETIDINE; DNA VACCINE; GAMMA INTERFERON; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B VACCINE; IMMUNOGLOBULIN A2; IMMUNOGLOBULIN G1; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 4; TRANSFORMING GROWTH FACTOR BETA;

ADJUVANT THERAPY; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN SPECIFICITY; ARTICLE; CD4+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; DNA IMMUNIZATION; DOWN REGULATION; DRUG MECHANISM; DRUG POTENCY; DRUG POTENTIATION; FEMALE; HUMORAL IMMUNITY; IMMUNOGENICITY; LYMPHOCYTE FUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODY FORMATION; CIMETIDINE; CYTOTOXICITY, IMMUNOLOGIC; FEMALE; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VACCINES; HISTAMINE H2 ANTAGONISTS; IMMUNITY, CELLULAR; INTERFERON TYPE II; INTERLEUKIN-12; INTERLEUKIN-4; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; T-LYMPHOCYTES, HELPER-INDUCER; T-LYMPHOCYTES, REGULATORY; VACCINATION; VACCINES, DNA;

ANIMALIA; HEPATITIS B VIRUS;

EID: 44749089175     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.04.191     Document Type: Article

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