메뉴 건너뛰기




Volumn 31, Issue 183, 2011, Pages 183-185

Role of lipoic acld in health and disease;Rola kwasu liponowego w zdrowiu i chorobie

Author keywords

Antioxidative activity; Lipoic acid; Therapeutic action

Indexed keywords

ANTIOXIDANT; CHELATING AGENT; HEAVY METAL; REACTIVE OXYGEN METABOLITE; THIOCTIC ACID;

EID: 80053646670     PISSN: 14269686     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (10)

References (47)
  • 1
    • 0142107431 scopus 로고    scopus 로고
    • Lipoic acid: A multifunctional antioxidant
    • Bast A., Haenen G. R.: Lipoic acid: a multifunctional antioxidant. Biofactors, 2003;17(1-4);207-213. (Pubitemid 37267155)
    • (2003) BioFactors , vol.17 , Issue.1-4 , pp. 207-213
    • Bast, A.1    Haenen, G.R.M.M.2
  • 2
    • 0030768236 scopus 로고    scopus 로고
    • The pharmacology of the antioxidant lipoic acid
    • Biewenga G., Haenen G., Bast A.: The pharmacology of the antioxidant lipoic acid. Gen. Pharmacol., 1997;29(3);315-331.
    • (1997) Gen. Pharmacol. , vol.29 , Issue.3 , pp. 315-331
    • Biewenga, G.1    Haenen, G.2    Bast, A.3
  • 3
    • 33644664987 scopus 로고    scopus 로고
    • Lipoic acid - The drug of future?
    • Bilska A., Wlodek L.: Lipoic acid - the drug of future? Pharmacol. Rep, 2005;57(5);570-577.
    • (2005) Pharmacol. Rep , vol.57 , Issue.5 , pp. 570-577
    • Bilska, A.1    Wlodek, L.2
  • 4
    • 77953022783 scopus 로고    scopus 로고
    • Inflammation and apoptosis in aortic tissues: Amelioration with alpha-lipoic acid through phosphatidylinositol 3-kinase/Akt-dependent mechanism
    • Bitar M. S., Ayed A. K., Abdel-Halim S. M. et al.: Inflammation and apoptosis in aortic tissues: amelioration with alpha-lipoic acid through phosphatidylinositol 3-kinase/Akt-dependent mechanism. Life Sci., 2010;86(23-24);844-853.
    • (2010) Life Sci. , vol.86 , Issue.23-24 , pp. 844-853
    • Bitar, M.S.1    Ayed, A.K.2    Abdel-Halim, S.M.3
  • 5
    • 64549088894 scopus 로고    scopus 로고
    • Lipoic acid improves hypertriglyceridemia by stimulating triacylglycerol clearance and down regulating liver triacylglycerol secretion
    • Butler J. A., Hagen T. M., Moreau R.: Lipoic acid improves hypertriglyceridemia by stimulating triacylglycerol clearance and down regulating liver triacylglycerol secretion. Arch. Biochem. Biophys., 2009;485(1);63-71.
    • (2009) Arch. Biochem. Biophys. , vol.485 , Issue.1 , pp. 63-71
    • Butler, J.A.1    Hagen, T.M.2    Moreau, R.3
  • 6
    • 80053624246 scopus 로고    scopus 로고
    • Lipoic acid suppresses compound 48/80-induced anaphylaxis-like reaction
    • Choi Y. H., Chai O. H., Han E. H. et al.: Lipoic acid suppresses compound 48/80-induced anaphylaxis-like reaction. Anat. Cell Biol., 2010;43(3);317-324.
    • (2010) Anat. Cell Biol. , vol.43 , Issue.3 , pp. 317-324
    • Choi, Y.H.1    Chai, O.H.2    Han, E.H.3
  • 7
    • 33750607920 scopus 로고    scopus 로고
    • Long-term safety of α-lipoic acid (ALA) consumption: A 2-year study
    • DOI 10.1016/j.yrtph.2006.06.003, PII S0273230006001139
    • Cremer D. R., Rabeler R., Roberts A. et al.: Long-term safety of a-lipoic acid (ALA) consumption: A 2-year study. Regul. Toxicol. Pharmacol., 2006;46(3);193-201. (Pubitemid 44692904)
    • (2006) Regulatory Toxicology and Pharmacology , vol.46 , Issue.3 , pp. 193-201
    • Cremer, D.R.1    Rabeler, R.2    Roberts, A.3    Lynch, B.4
  • 9
    • 77954371707 scopus 로고    scopus 로고
    • Neutraceuticals in diabetes and metabolic syndrome
    • Davi G., Santilli R, Patrono C: Neutraceuticals in diabetes and metabolic syndrome. Cardiovasc. Ther., 2010;28(4);216-226.
    • (2010) Cardiovasc. Ther. , vol.28 , Issue.4 , pp. 216-226
    • Davi, G.1    Santilli, R.2    Patrono, C.3
  • 10
    • 77955392823 scopus 로고    scopus 로고
    • Ibuprofen and lipoic acid diamide as co-drug with neuroprotective activity: Pharmacological properties and effects in beta-amyloid (1-40) infused Alzheimer's disease rat model
    • Di Stefano A., Sozio P., Cerasa L. S. et al.: Ibuprofen and lipoic acid diamide as co-drug with neuroprotective activity: pharmacological properties and effects in beta-amyloid (1-40) infused Alzheimer's disease rat model. Int. J. Immunopathol., 2010;23(2);589-599.
    • (2010) Int. J. Immunopathol. , vol.23 , Issue.2 , pp. 589-599
    • Di Stefano, A.1    Sozio, P.2    Cerasa, L.S.3
  • 11
    • 77953455188 scopus 로고    scopus 로고
    • Structural, chemical and biological aspects of antioxidants for strategies against metal and metaloid exposure
    • Flora S. J.: Structural, chemical and biological aspects of antioxidants for strategies against metal and metaloid exposure. Oxid. Med. Cell Longev., 2009;2(4);191-206.
    • (2009) Oxid. Med. Cell Longev. , vol.2 , Issue.4 , pp. 191-206
    • Flora, S.J.1
  • 12
    • 74349096419 scopus 로고    scopus 로고
    • Antioxidant properties of an endogenous thiol: Alpha-lipoic acid used in the prevention of cardiovascular diseases
    • Ghibu S., Richard C., Vergely C. et al.: Antioxidant properties of an endogenous thiol: alpha-lipoic acid used in the prevention of cardiovascular diseases. J. Cardiovasc. Pharmacol., 2009;54(3);391-398.
    • (2009) J. Cardiovasc. Pharmacol. , vol.54 , Issue.3 , pp. 391-398
    • Ghibu, S.1    Richard, C.2    Vergely, C.3
  • 13
    • 64649102599 scopus 로고    scopus 로고
    • Prophylaxis with alpha-lipoic acid against lipopolysaccharide-induced brain injury in rats
    • Goraca A., Aslanowicz-Antkowiak K.: Prophylaxis with alpha-lipoic acid against lipopolysaccharide-induced brain injury in rats. Arch. Immunol. Ther. Exp. (Warsz), 2009;57(2);141-146.
    • (2009) Arch. Immunol. Ther. Exp. (Warsz) , vol.57 , Issue.2 , pp. 141-146
    • Goraca, A.1    Aslanowicz-Antkowiak, K.2
  • 14
    • 46849096052 scopus 로고    scopus 로고
    • Beneficial effect of α-lipoic acid on lipopolysaccharide-induced oxidative stress in bronchoalveolar lavage fluid
    • Gora̧ca A., Skibska B.: Beneficial effect of alpha-lipoic acid on lipopolysaccharide-induced oxidative stress in bronchoalveolar lavage fluid. J. Physiol. Pharmacol., 2008;59(2);379-386. (Pubitemid 351955759)
    • (2008) Journal of Physiology and Pharmacology , vol.59 , Issue.2 , pp. 379-386
    • Goraca, A.1    Skibska, B.2
  • 15
    • 75149165328 scopus 로고    scopus 로고
    • Alpha-lipoic acid improves vascular endothelial function in patients with type 2 diabetes: A placebocontrolled randomized trial
    • Heinisch B. B., Francesconi M., Mittermayer F. et al.: Alpha-lipoic acid improves vascular endothelial function in patients with type 2 diabetes: a placebocontrolled randomized trial. Eur. J. Clin. Invest., 2010;40(2);148-154.
    • (2010) Eur. J. Clin. Invest. , vol.40 , Issue.2 , pp. 148-154
    • Heinisch, B.B.1    Francesconi, M.2    Mittermayer, F.3
  • 16
    • 77952174536 scopus 로고    scopus 로고
    • Protective effects of irbesartan and alpha lipoic acid in STZ-induced diabetic nephropathy in rats
    • Kanter M., Sen S., Donmez S. et al.: Protective effects of irbesartan and alpha lipoic acid in STZ-induced diabetic nephropathy in rats. Ren. Fail., 2010;32(4);498-505.
    • (2010) Ren. Fail. , vol.32 , Issue.4 , pp. 498-505
    • Kanter, M.1    Sen, S.2    Donmez, S.3
  • 17
    • 0036431462 scopus 로고    scopus 로고
    • Inhibition of LPS-induced nitric oxide and TNF-α production by α-lipoic acid in rat Kupffer cells and in RAW 264.7 murine macrophages
    • DOI 10.1046/j.1440-1711.2002.01124.x
    • Kiemer A. K., Muller C., Vollmar A. M.: Inhibition of LPS-induced nitric oxide and TNF-alpha production by alpha-lipoic acid in rat Kupffer cells and in RAW 264.7 murine macrophages. Immunol. Cell Biol., 2002;80(6);550-557. (Pubitemid 35335018)
    • (2002) Immunology and Cell Biology , vol.80 , Issue.6 , pp. 550-557
    • Kiemer, A.K.1    Muller, C.2    Vollmar, A.M.3
  • 20
    • 78650694937 scopus 로고    scopus 로고
    • Effects of alpha-lipoic acid on body weight in obese subjects
    • 1-8
    • Koh E. H., Lee W. J., Lee S. A. et al.: Effects of alpha-lipoic acid on body weight in obese subjects. Am. J. Med., 2011;124(1);85.e 1-8.
    • (2011) Am. J. Med. , vol.124 , Issue.1
    • Koh, E.H.1    Lee, W.J.2    Lee, S.A.3
  • 21
    • 19744372144 scopus 로고    scopus 로고
    • Alpha-lipoic acid increases insulin sensitivity by activating AMPK in skeletal muscle
    • Lee W. J., Song K. H., Koh E. H. et al.: Alpha-lipoic acid increases insulin sensitivity by activating AMPK in skeletal muscle. Biochem. Biophys. Res. Commun., 2005;8;332(3);885-891.
    • (2005) Biochem. Biophys. Res. Commun. , vol.8-332 , Issue.3 , pp. 885-891
    • Lee, W.J.1    Song, K.H.2    Koh, E.H.3
  • 22
    • 68049134264 scopus 로고    scopus 로고
    • Molecular mechanisms of lipoic acid modulation of T-type calcium channels in pain pathway
    • Lee W. Y., Orestes P., Latham J. et al.: Molecular mechanisms of lipoic acid modulation of T-type calcium channels in pain pathway. J. Neurosci., 2009;29(30);9500-9509.
    • (2009) J. Neurosci. , vol.29 , Issue.30 , pp. 9500-9509
    • Lee, W.Y.1    Orestes, P.2    Latham, J.3
  • 23
    • 51449084024 scopus 로고    scopus 로고
    • Lipoic acid as an anti-inflammatory and neuroprotective treatment for Alzheimer's disease
    • Maczurek A., Hager K., Kenklies M. et al.: Lipoic acid as an anti-inflammatory and neuroprotective treatment for Alzheimer's disease. Adv. Drug Delivery Rev., 2008;60(13-14);1463-1470.
    • (2008) Adv. Drug Delivery Rev. , vol.60 , Issue.13-14 , pp. 1463-1470
    • Maczurek, A.1    Hager, K.2    Kenklies, M.3
  • 24
    • 33845977178 scopus 로고    scopus 로고
    • Lipoic acid: Characteristics and therapeutic applications
    • Malinska D., Winiarska K.: Lipoic acid: characteristics and therapeutic applications. Post Hig. Med. Dosw., 2005;59;535-543.
    • (2005) Post Hig. Med. Dosw. , vol.59 , pp. 535-543
    • Malinska, D.1    Winiarska, K.2
  • 25
    • 77951943315 scopus 로고    scopus 로고
    • Alpha lipoic acid: A new treatment for neuropathic pain in patients with diabetes
    • Mijnhout G. S., Alkhalaf A., Kleefstra N. et al.: Alpha lipoic acid: a new treatment for neuropathic pain in patients with diabetes. Neth. J. Med., 2010;68(4);158-162.
    • (2010) Neth. J. Med. , vol.68 , Issue.4 , pp. 158-162
    • Mijnhout, G.S.1    Alkhalaf, A.2    Kleefstra, N.3
  • 26
    • 0029764551 scopus 로고    scopus 로고
    • Alpha-lipoic acid: Antioxidant potency against lipid peroxidation of neural tissues in vitro and implications for diabetic neuropathy
    • DOI 10.1016/0891-5849(96)00172-4
    • Nickander K. K., McPhee B. R., Low P. A. et al.: Alpha-lipoic acid: antioxidant potency against lipid peroxidation of neural tissues in vitro and implications for diabetic neuropathy. Free Radic. Biol. Med., 1996;21(5);631-639. (Pubitemid 26331093)
    • (1996) Free Radical Biology and Medicine , vol.21 , Issue.5 , pp. 631-639
    • Nickander, K.K.1    McPhee, B.R.2    Low, P.A.3    Tritschler, H.4
  • 27
    • 79951681009 scopus 로고    scopus 로고
    • α-Lipoic acid has anti-inflammatory and anti-oxidative properties: An experimental study in rats with carrageenan-induced acute and cotton pellet-induced chronic inflammations
    • Odabasoglu F., Halici Z., Aygun H. et al.: α-Lipoic acid has anti-inflammatory and anti-oxidative properties: an experimental study in rats with carrageenan-induced acute and cotton pellet-induced chronic inflammations. Br. J. Nutr., 2011;105(1);31-43.
    • (2011) Br. J. Nutr. , vol.105 , Issue.1 , pp. 31-43
    • Odabasoglu, F.1    Halici, Z.2    Aygun, H.3
  • 28
    • 0029909010 scopus 로고    scopus 로고
    • Neuroprotection by the metabolic antioxidant alpha-lipoic acid
    • Packer L., Tritschler H. J., Wessel K.: Neuroprotection by the metabolic antioxidant alpha-lipoic acid. Free Radic. Biol. Med., 1997;22(1-2);359-378.
    • (1997) Free Radic. Biol. Med. , vol.22 , Issue.1-2 , pp. 359-378
    • Packer, L.1    Tritschler, H.J.2    Wessel, K.3
  • 30
    • 0034773628 scopus 로고    scopus 로고
    • Molecular aspects of lipoic acid in the prevention of diabetes complications
    • DOI 10.1016/S0899-9007(01)00658-X, PII S089990070100658X
    • Packer L., Kraemer K., Rimbach G.: Molecular aspects of lipoic acid in the prevention of diabetes complications. Nutrition, 2001;17(10);888-895. (Pubitemid 33001657)
    • (2001) Nutrition , vol.17 , Issue.10 , pp. 888-895
    • Packer, L.1    Kraemer, K.2    Rimbach, G.3
  • 31
    • 77954560215 scopus 로고    scopus 로고
    • Complementary therapy in diabetic patients with chronic complications; a pilot study
    • Palacka P., Kucharska J., Murin J. et al.: Complementary therapy in diabetic patients with chronic complications; a pilot study. Brat. Lek. Listy, 2010;111(4);205-211.
    • (2010) Brat. Lek. Listy , vol.111 , Issue.4 , pp. 205-211
    • Palacka, P.1    Kucharska, J.2    Murin, J.3
  • 32
    • 68949215058 scopus 로고    scopus 로고
    • The comparison of alpha-lipoic acid, melatonin, vitamin C and trolox effectiveness in decreasing DNA stand brakes and increasing plasma antioxidant power
    • Piechota A., Gora̧ca A.: The comparison of alpha-lipoic acid, melatonin, vitamin C and trolox effectiveness in decreasing DNA stand brakes and increasing plasma antioxidant power. Pol. Merk. Lek., 2009;27(157);19-21.
    • (2009) Pol. Merk. Lek. , vol.27 , Issue.157 , pp. 19-21
    • Piechota, A.1    Gora̧ca, A.2
  • 33
    • 79959929057 scopus 로고    scopus 로고
    • Lipoic acid inhibits leptin secretion and Sp1 activity in adipocytes
    • doi:10.1002/mnfr.201000534 w druku
    • Prieto-Hontoria P. L., Pérez-Matute P., Femández-Galilea M. et al.: Lipoic acid inhibits leptin secretion and Sp1 activity in adipocytes. Mol. Nutr. Food Res., 2011, doi:10.1002/mnfr.201000534 [w druku].
    • (2011) Mol. Nutr. Food Res.
    • Prieto-Hontoria, P.L.1    Pérez-Matute, P.2    Femández-Galilea, M.3
  • 34
    • 0002908647 scopus 로고
    • Crystalline a-lipoic acid; a catalytic agent associated with pyruvate dehydrogenase
    • Reed L. J., De Busk B. G., Gansalusic I. C. et al.: Crystalline a-lipoic acid; a catalytic agent associated with pyruvate dehydrogenase. Science, 1951;114(2952);93-94.
    • (1951) Science , vol.114 , Issue.2952 , pp. 93-94
    • Reed, L.J.1    De Busk, B.G.2    Gansalusic, I.C.3
  • 35
    • 0031605517 scopus 로고    scopus 로고
    • From lipoic acid to multi-enzyme complex
    • Reed L. J.: From lipoic acid to multi-enzyme complex. Protein Sci., 1998;7(1);220-224.
    • (1998) Protein Sci. , vol.7 , Issue.1 , pp. 220-224
    • Reed, L.J.1
  • 38
    • 0029984062 scopus 로고    scopus 로고
    • Antioxidant and redox regulation of gene transcription
    • Sen C. K., Packer L.: Antioxidant and redox regulation of gene transcription. FASEB J., 1996;10(7);709-720. (Pubitemid 26172817)
    • (1996) FASEB Journal , vol.10 , Issue.7 , pp. 709-720
    • Sen, C.K.1    Packer, L.2
  • 39
    • 69949104384 scopus 로고    scopus 로고
    • Alpha-lipoic acid as a dietary supplement: Molecular mechanisms and therapeutic potential
    • Shay K. P., Moreau R. F., Smith E. J. et al.: Alpha-lipoic acid as a dietary supplement: Molecular mechanisms and therapeutic potential. Biochim. Biophys. Acta, 2009;1790(10);1149-1160.
    • (2009) Biochim. Biophys. Acta , vol.1790 , Issue.10 , pp. 1149-1160
    • Shay, K.P.1    Moreau, R.F.2    Smith, E.J.3
  • 40
    • 54949103935 scopus 로고    scopus 로고
    • Alpha-lipoic acid supplementation and diabetes
    • Singh U., Jialal I.: Alpha-lipoic acid supplementation and diabetes. Nutr. Rev., 2008;66(11);646-657.
    • (2008) Nutr. Rev. , vol.66 , Issue.11 , pp. 646-657
    • Singh, U.1    Jialal, I.2
  • 41
    • 0030840042 scopus 로고    scopus 로고
    • Differential effects of lipoic acid stereoisomers on glucose metabolism in insulin-resistant skeletal muscle
    • 1
    • Streeper R. S., Henriksen E. J., Jacob S. et al.: Differential effects of lipoic acid stereoisomers on glucose metabolism in insulin-resistant skeletal muscle. Am. J. Physiol., 1997;273(1 Pt 1);E185-E191.
    • (1997) Am. J. Physiol. , vol.273 , Issue.1 PART
    • Streeper, R.S.1    Henriksen, E.J.2    Jacob, S.3
  • 44
    • 0027297705 scopus 로고
    • Antioxidant activities of dihydrolipoic acid and its structural homologues
    • Suzuki Y. J., Tsuchiya M., Packer L.: Antioxidant activities of dihydrolipoic acid and its structural homologues. Free Radic. Res. Commun., 1993;18(2);115-122. (Pubitemid 23173513)
    • (1993) Free Radical Research Communications , vol.18 , Issue.2 , pp. 115-122
    • Suzuki, Y.J.1    Tsuchiya, M.2    Packer, L.3
  • 45
    • 77953203617 scopus 로고    scopus 로고
    • Pathomechanism of diabetic neuropathy: Background of the pathogenesis-oriented therapy
    • Winkler G., Kempler P.: Pathomechanism of diabetic neuropathy: background of the pathogenesis-oriented therapy. Orv. Hetil., 2010;151(24);971-981.
    • (2010) Orv. Hetil. , vol.151 , Issue.24 , pp. 971-981
    • Winkler, G.1    Kempler, P.2
  • 46
    • 77957983169 scopus 로고    scopus 로고
    • Alzheimer Disease: The pros and cons of pharmaceutical, nutritional, botanical, and stimulatory therapies, with a discussion of treatment strategies from the perspective of patients and practitioners
    • Wollen K. A.: Alzheimer Disease: The pros and cons of pharmaceutical, nutritional, botanical, and stimulatory therapies, with a discussion of treatment strategies from the perspective of patients and practitioners. Altera Med. Rev., 2010;15(3);223-244.
    • (2010) Altera Med. Rev. , vol.15 , Issue.3 , pp. 223-244
    • Wollen, K.A.1
  • 47
    • 0242661909 scopus 로고    scopus 로고
    • Alpha-lipoic acid and cardiovascular disease
    • Wollin S. D., Jones P. J.: Alpha-lipoic acid and cardiovascular disease. J. Nutr., 2003;133(11);3327-3330.
    • (2003) J. Nutr. , vol.133 , Issue.11 , pp. 3327-3330
    • Wollin, S.D.1    Jones, P.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.