Safety evaluation of α-lipoic acid (ALA)

Regulatory Toxicology and Pharmacology

Volumn 46, Issue 1, 2006, Pages 29-41

  Cremer, D R ^a   Rabeler, R ^a   Roberts, A ^b   Lynch, B ^b  

^a EVONIK INDUSTRIES AG   (Germany)

^b Cantox Health Sciences International   (Canada)

Author keywords

lipoic acid; 4 Week study; Acute; Adverse; Ames; Clastinogenicity; Micronucleus; Mutagenicity; Safety; Subchronic; Thioctic acid; Toxicity

Indexed keywords

ALANINE AMINOTRANSFERASE; GLUTAMATE DEHYDROGENASE; LIVER ENZYME; THIOCTIC ACID;

AMES TEST; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BACTERIAL STRAIN; CLINICAL CHEMISTRY; CLONIC SEIZURE; CONTROLLED STUDY; COORDINATION DISORDER; DRUG SAFETY; DRUG SCREENING; FEMALE; GENOTOXICITY; HEMATOLOGICAL PARAMETERS; HISTOPATHOLOGY; HYPOKINESIA; LIVER; MALE; MAMMARY GLAND; MICRONUCLEUS TEST; MUTAGEN TESTING; MUTAGENIC ACTIVITY; MUTAGENICITY; NONHUMAN; ORGAN WEIGHT; PRIORITY JOURNAL; RAT; RAT STRAIN; SALMONELLA TYPHIMURIUM; SEX RATIO; STATISTICAL SIGNIFICANCE; TOXICITY TESTING; WEIGHT GAIN;

ACUTE TOXICITY TESTS; ANIMALS; ANTIOXIDANTS; BEHAVIOR, ANIMAL; BODY WEIGHT; DRUG TOXICITY; EATING; FEMALE; MALE; MICRONUCLEUS TESTS; MUTAGENICITY TESTS; NO-OBSERVED-ADVERSE-EFFECT LEVEL; RATS; RATS, WISTAR; SALMONELLA TYPHIMURIUM; THIOCTIC ACID;

ANIMALIA; BACTERIA (MICROORGANISMS); RATTUS NORVEGICUS; SALMONELLA TYPHIMURIUM;

EID: 33747884249     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2006.06.004     Document Type: Article

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