Hyperforin changes the zinc-storage capacities of brain cells

Neuropharmacology

Volumn 61, Issue 8, 2011, Pages 1321-1326

  Gibon, Julien ^a,e   Richaud, Pierre ^b,c,d   Bouron, Alexandre ^a,e  

^a CEA GRENOBLE   (France)

^b DIF   (France)

^c CNRS   (France)

^d AIX MARSEILLE UNIVERSITY   (France)

^e UNIV GRENOBLE ALPES   (France)

Author keywords

Calcium; Calcium channels; Calcium stores; Hyperforin; Mice; Neurones; Zinc

Indexed keywords

CALCIUM ION; HYPERFORIN; IONOMYCIN; METALLOTHIONEIN I; METALLOTHIONEIN II; METALLOTHIONEIN III; SULFUR; THYMIDINE DIPHOSPHATE; ZINC ION;

ADULT ANIMAL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN MITOCHONDRION; BRAIN NERVE CELL; CALCIUM MOBILIZATION; CONTROLLED STUDY; GENE EXPRESSION; IN VITRO STUDY; IN VIVO STUDY; LONG TERM EXPOSURE; MALE; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; ZINC METABOLISM; ZINC MOBILIZATION; ZINC STORAGE;

2,2'-DIPYRIDYL; ANIMALS; BRAIN; CALCIUM; CELLS, CULTURED; CHELATING AGENTS; DISULFIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHYLENEDIAMINES; GENE EXPRESSION REGULATION; IONOMYCIN; MALE; MATRIX METALLOPROTEINASES; MICE; MICE, INBRED C57BL; MITOCHONDRIA; NEURONS; OXIDANTS; PHLOROGLUCINOL; SULFUR; TERPENES; TIME FACTORS; ZINC;

EID: 80053613335     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2011.08.002     Document Type: Article

References (39)

1. E. Aizenman, A.K. Stout, K.A. Hartnett, K.E. Dineley, B. McLaughlin, and I.J. Reynolds Induction of neuronal apoptosis by thiol oxidation: putative role of intracellular zinc release J. Neurochem. 75 2000 1878 1888
2. A. Bouron, S. Boisseau, M. De Waard, and L. Peris Differential down-regulation of voltage-gated calcium channel currents by glutamate and BDNF in embryonic cortical neurons Eur. J. Neurosci. 24 2006 699 708 (Pubitemid 44232516)
3. J.T. Brosnan, and M.E. Brosnan The sulfur-containing amino acids: an overview J. Nutr. 136 2006 1636S 1640S (Pubitemid 43765374)
4. S. Chatterjee, V. Filippov, P. Lishko, O. Maximyuk, M. Noldner, and O. Krishtal Hyperforin attenuates various ionic conductance mechanisms in the isolated hippocampal neurons of rat Life Sci. 65 1999 2395 2405 (Pubitemid 29531042)
5. S.S. Chatterjee, S.K. Bhattacharya, M. Wonnemann, A. Singer, and W.E. Muller Hyperforin as a possible antidepressant component of hypericum extracts Life Sci. 63 1998 499 510 (Pubitemid 28367402)
6. G. Di Carlo, F. Borrelli, E. Ernst, and A.A. Izzo St John's wort: prozac from the plant kingdom Trends Pharmacol. Sci. 22 2001 292 297 (Pubitemid 32523912)
7. K.R. Gee, Z.L. Zhou, D. Ton-That, S.L. Sensi, and J.H. Weiss Measuring zinc in living cells. A new generation of sensitive and selective fluorescent probes Cell Calcium 31 2002 245 251 (Pubitemid 34778060)
8. J. Gibon, P. Tu, V. Frazzini, S.L. Sensi, and A. Bouron The thiol-modifying agent N-ethylmaleimide elevates the cytosolic concentration of free Zn(2+) but not of Ca(2+) in murine cortical neurons Cell Calcium 48 2010 37 43
9. T.N. Griffith, L. Varela-Nallar, M.C. Dinamarca, and N.C. Inestrosa Neurobiological effects of hyperforin and its potential in Alzheimer's disease therapy Curr. Med. Chem. 17 2010 391 406
10. S.T. Kaehler, C. Sinner, S.S. Chatterjee, and A. Philippu Hyperforin enhances the extracellular concentrations of catecholamines, serotonin and glutamate in the rat locus coeruleus Neurosci. Lett. 262 1999 199 202 (Pubitemid 29136804)
11. A.R. Kay Detecting and minimizing zinc contamination in physiological solutions BMC Physiol. 4 2004 4
12. E. Koch, and S.S. Chatterjee Hyperforin stimulates intracellular calcium mobilisation and enhances extracellular acidification in DDT1-MF2 smooth muscle cells Pharmacopsychiatry 34 Suppl. 1 2001 S70 S73
13. L.A. Komarnisky, R.J. Christopherson, and T.K. Basu Sulfur: its clinical and toxicologic aspects Nutrition 19 2003 54 61 (Pubitemid 36044487)
14. B.J. Komoroski, S. Zhang, H. Cai, J.M. Hutzler, R. Frye, T.S. Tracy, S.C. Strom, T. Lehmann, C.Y. Ang, Y.Y. Cui, and R. Venkataramanan Induction and inhibition of cytochromes P450 by the St. John's wort constituent hyperforin in human hepatocyte cultures Drug Metab. Dispos. 32 2004 512 518 (Pubitemid 38535029)
15. B. Kraus, H. Wolff, E.F. Elstner, and J. Heilmann Hyperforin is a modulator of inducible nitric oxide synthase and phagocytosis in microglia and macrophages Naunyn Schmiedebergs Arch. Pharmacol. 381 2010 541 553
16. V. Kumar, A. Mdzinarishvili, C. Kiewert, T. Abbruscato, U. Bickel, C.J. van der Schyf, and J. Klein NMDA receptor-antagonistic properties of hyperforin, a constituent of St. John's wort J. Pharmacol. Sci. 102 2006 47 54 (Pubitemid 44440966)
17. K. Leuner, V. Kazanski, M. Muller, K. Essin, B. Henke, M. Gollasch, C. Harteneck, and W.E. Muller Hyperforin - a key constituent of St. John's wort specifically activates TRPC6 channels FASEB J. 21 2007 4101 4111 (Pubitemid 350232367)
18. K. Linde, G. Ramirez, C.D. Mulrow, A. Pauls, W. Weidenhammer, and D. Melchart St John's wort for depression - an overview and meta-analysis of randomised clinical trials BMJ 313 1996 253 258 (Pubitemid 26254730)
19. J.Y. Liu, Z. Liu, D.M. Wang, M.M. Li, S.X. Wang, R. Wang, J.P. Chen, Y.F. Wang, and D.P. Yang Induction of apoptosis in K562 cells by dicyclohexylammonium salt of hyperforin through a mitochondrial-related pathway Chem. Biol. Interact. 2011
20. W. Maret Zinc coordination environments in proteins determine zinc functions J. Trace Elem. Med. Biol. 19 2005 7 12 (Pubitemid 41258175)
21. W. Maret Molecular aspects of human cellular zinc homeostasis: redox control of zinc potentials and zinc signals Biometals 22 2009 149 157
22. W. Maret, and Y. Li Coordination dynamics of zinc in proteins Chem. Rev. 109 2009 4682 4707
23. M.A. Medina, B. Martinez-Poveda, M.I. Amores-Sanchez, and A.R. Quesada Hyperforin: more than an antidepressant bioactive compound? Life Sci. 79 2006 105 111 (Pubitemid 43737058)
24. L.B. Moore, B. Goodwin, S.A. Jones, G.B. Wisely, C.J. Serabjit-Singh, T.M. Willson, J.L. Collins, and S.A. Kliewer St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor Proc. Natl. Acad. Sci. U. S. A. 97 2000 7500 7502 (Pubitemid 30431492)
25. M. Muller, K. Essin, K. Hill, H. Beschmann, S. Rubant, C.M. Schempp, M. Gollasch, W.H. Boehncke, C. Harteneck, W.E. Muller, and K. Leuner Specific TRPC6 channel activation, a novel approach to stimulate keratinocyte differentiation J. Biol. Chem. 283 2008 33942 33954
26. W.E. Muller Current St John's wort research from mode of action to clinical efficacy Pharmacol. Res. 47 2003 101 109 (Pubitemid 36263444)
27. P. Nathan The experimental and clinical pharmacology of St John's wort (Hypericum perforatum L.) Mol. Psychiatry 4 1999 333 338 (Pubitemid 29440572)
28. M. Penkowa Metallothioneins are multipurpose neuroprotectants during brain pathology FEBS J. 273 2006 1857 1870
29. E. Rousselet, P. Richaud, T. Douki, J.G. Chantegrel, A. Favier, A. Bouron, and J.M. Moulis A zinc-resistant human epithelial cell line is impaired in cadmium and manganese import Toxicol. Appl. Pharmacol. 230 2008 312 319
30. C.M. Schempp, K. Pelz, A. Wittmer, E. Schopf, and J.C. Simon Antibacterial activity of hyperforin from St John's wort, against multiresistant Staphylococcus aureus and gram-positive bacteria Lancet 353 1999 2129 (Pubitemid 29278489)
31. C.M. Schempp, V. Kirkin, B. Simon-Haarhaus, A. Kersten, J. Kiss, C.C. Termeer, B. Gilb, T. Kaufmann, C. Borner, J.P. Sleeman, and J.C. Simon Inhibition of tumour cell growth by hyperforin, a novel anticancer drug from St. John's wort that acts by induction of apoptosis Oncogene 21 2002 1242 1250 (Pubitemid 34185241)
32. S.L. Sensi, D. Ton-That, P.G. Sullivan, E.A. Jonas, K.R. Gee, L.K. Kaczmarek, and J.H. Weiss Modulation of mitochondrial function by endogenous Zn2+ pools Proc. Natl. Acad. Sci. U. S. A. 100 2003 6157 6162 (Pubitemid 36576947)
33. Y. Shibayama, A. Kawachi, S. Onimaru, J. Tokunaga, R. Ikeda, K. Nishida, S. Kuchiiwa, S. Nakagawa, N. Takamura, T. Motoya, Y. Takeda, and K. Yamada Effect of pre-treatment with St John's wort on nephrotoxicity of cisplatin in rats Life Sci. 81 2007 103 108 (Pubitemid 46921171)
34. +1 J. Pharmacol. Exp. Ther 290 1999 1363 1368 (Pubitemid 29400281)
35. N. Thirumoorthy, K.T. Manisenthil Kumar, A. Shyam Sundar, L. Panayappan, and M. Chatterjee Metallothionein: an overview World J. Gastroenterol. 13 2007 993 996 (Pubitemid 46510998)
36. D. Thomas, S.C. Tovey, T.J. Collins, M.D. Bootman, M.J. Berridge, and P. Lipp A comparison of fluorescent Ca2+ indicator properties and their use in measuring elementary and global Ca2+ signals Cell Calcium 28 2000 213 223
37. P. Tu, J. Gibon, and A. Bouron The TRPC6 channel activator hyperforin induces the release of zinc and calcium from mitochondria J. Neurochem. 112 2010 204 213
38. M. Vasak Advances in metallothionein structure and functions J. Trace Elem. Med. Biol. 19 2005 13 17 (Pubitemid 41253912)
39. A.K. West, J. Hidalgo, D. Eddins, E.D. Levin, and M. Aschner Metallothionein in the central nervous system: roles in protection, regeneration and cognition Neurotoxicology 29 2008 488 502