Camptothecin derivative-loaded poly(caprolactone-co-lactide)-b-PEG-b- poly(caprolactone-co-lactide) nanoparticles and their biodistribution in mice

Journal of Controlled Release

Volumn 96, Issue 1, 2004, Pages 135-148

  Zhang, Leyang ^a   Hu, Yong ^a   Jiang, Xiqun ^a   Yang, Changzheng ^a   Lu, Wei ^b   Yang, Yong Hua ^a  

^a NANJING UNIVERSITY   (China)

^b SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Block copolymers; Camptothecin; Drug delivery systems; Nanoparticles

Indexed keywords

ATOMIC FORCE MICROSCOPY; COPOLYMERIZATION; NANOSTRUCTURED MATERIALS; RING OPENING POLYMERIZATION; SYNTHESIS (CHEMICAL); TUMORS;

RING OPENING COPOLYMERIZATION; TRIBLOCK COPOLYMERS;

ORGANIC POLYMERS;

10 HYDROXYCAMPTOTHECIN; 10 HYDROXYCAMPTOTHECIN 10,20 DIISOBUTYL DICARBONATE; ANTINEOPLASTIC AGENT; CAMPTOTHECIN DERIVATIVE; COPOLYMER; LACTONE DERIVATIVE; NANOPARTICLE; POLY(CAPROLACTONE CO LACTIDE) BLOCK POLY(ETHYLENE GLYCOL) BLOCK POLY(CAPROLACTONE CO LACTIDE); UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATOMIC FORCE MICROSCOPY; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG RELEASE; DRUG SYNTHESIS; LIGHT SCATTERING; MOUSE; NONHUMAN; PARTICLE SIZE; POLYMERIZATION; PRECIPITATION; PRIORITY JOURNAL; RING OPENING; SUSTAINED DRUG RELEASE; TISSUE DISTRIBUTION; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; BIOLOGICAL AVAILABILITY; CAMPTOTHECIN; MICE; MICE, INBRED C57BL; NANOTECHNOLOGY; POLYESTERS; POLYETHYLENE GLYCOLS; TISSUE DISTRIBUTION;

EID: 1842525951     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2004.01.010     Document Type: Article

References (30)

1. Gref R., Minamitake Y., Peracchia M.T., Trebetskoy V.S., Torchilin V.P., Langer R. Biodegradable long-circulating polymeric nanospheres. Science. 263:1994;1600-1603.
2. Yasugi K., Nagasaki Y., Kato M., Kataoka K. Preparation and characterization of polymer micelles from poly(ethylene glycol)-poly(D,L- lactide) block copolymers as potential drug carrier. J. Control. Release. 62:1999;89-100.
3. Savić R., Luo L., Eisenberg A., Maysinger D. Micellar nanocontainers distribute to defined cytoplasmic organelles. Science. 300:2003;615-618.
4. Riley T., Stolnik S., Heald C.R., Xiong C.D., Garnett M.C., Illum L., Davis S.S. Physicochemical evaluation of nanoparticles assembled from poly(lactic acid)-poly(ethylene glycol) (PLA-PEG) block copolymers as drug delivery vehicles. Langmuir. 17:2001;3168-3174.
5. Kwon G.S., Okano T. Polymeric micelles as new drug carriers. Adv. Drug Deliv. Rev. 21:1996;107-116.
6. Moghimi S.M., Hunter A.C., Murray J.C. Long-circulating and target-specific nanoparticles: theory to practice. Pharmacol. Rev. 53:2001;283-318.
7. Gref R., Lueck M., Quellec P., Marchand M., Dellacherie E., Harnisch S., Blunk T., Müller R.H. 'Stealth' corona-core nanoparticles surface modified by polyethylene glycol (PEG): influences of the corona (PEG chain length and surface density) and of the core composition on phagocytic uptake and plasma protein adsorption. Colloids Surf., B Biointerfaces. 18:2000;301-313.
8. Zambaux M.F., Bonneaux F., Gref R., Dellacherie E., Vigneron C. MPEO-PLA nanoparticles: effect of MPEO content on some of their surface properties. J. Biomed. Mater. Res. 44:1999;109-115.
9. Maeda H., Wu J., Sawa T., Matsumura Y., Hori K. Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. J. Control. Release. 65:2000;271-284.
10. Kwon G.S., Suwa S., Yokoyama M., Okano T., Sakurai S., Kataoka K. Enhanced tumor accumulation and prolonged circulation times of micelle-forming poly(ethylene oxide-aspartate) block copolymer-adriamycin conjugates. J. Control. Release. 29:1994;17-23.
11. Yokoyama M., Fukushima S., Uehara R., Okamoto K., Kataoka K., Sakurai Y., Okano T. Characterization of physical entrapment and chemical conjugation of adriamycin in polymeric micelles and their design for in vivo delivery to a solid tumor. J. Control. Release. 50:1998;79-92.
12. Wall M.E., Wani M.C., Cook C.E., Palmer K.H., McPhail A.T., Sim G.A. Plant antitumor agents: I. The isolation and structure of camptothecin, a novel alkaloidal leukemia and tumour inhibitor from camptotheca acuminata. J. Am. Chem. Soc. 88:1966;3888-3890.
13. Jaxel C., Kohn K.W., Wani M.C., Wall M.E., Prommier Y. Structure-activity study of the actions of camptothecin derivatives on mammalian topoisomerase: I. Evidence for a specific receptor site and for a relation to antitumor activity. Cancer Res. 49:1989;1465-1469.
14. Rothenberg M.L. Topoisomerase I inhibitors: review and update. Ann. Oncol. 8:1997;837-855.
15. O'Leary J., Muggia F.M. Camptothecins: a review of their development and schedules of administration. Eur. J. Cancer. 34:1998;1500-1508.
16. Cao Z., Harris N., Kozielski A., Vardeman D., Stehlin J.S., Giovanella B. Alkyl esters of camptothecin and 9-nitrocamptothecin: synthesis, in vitro pharmacokinetics, toxicity, and antitumor activity. J. Med. Chem. 41:1998;31-37.
17. Zhao H., Lee C., Sai P., Choe Y.H., Boro M., Pendri A., Guan S., Greenwald R.B. 20-O-acylcamptothecin derivatives: evidence for lactone stabilization. J. Org. Chem. 65:2000;4601-4606.
18. Hatefi A., Amsden B. Camptothecin delivery methods. Pharm. Res. 19:2002;1389-1399.
19. Kim S.Y., Lee Y.M. Taxol-loaded block copolymer nanospheres composed of methoxy poly(ethylene glycol) and poly(ε-caprolactone) as novel anticancer drug carriers. Biomaterials. 22:2001;1697-1704.
20. Ertl B., Platzer P., Wirth M., Gabor F. Poly(D,L-lactic-co-glycolic acid) microspheres for sustained delivery and stabilization of camptothecin. J. Control. Release. 61:1999;305-317.
21. Shenderova A., Burke T.G., Schwendeman S.P. Stabilization of 10-hydroxycamptothecin in poly(lactide-co-glycolide) microsphere delivery vehicles. Pharm. Res. 14:1997;1406-1414.
22. Hu Y., Jiang X., Ding Y., Zhang L., Yang C., Zhang J., Chen J., Yang Y. Preparation and drug release behaviors of nimodipine-loaded poly(caprolactone)- poly(ethylene oxide)-polylactide amphiphilic copolymer nanoparticles. Biomaterials. 24:2003;2395-2404.
23. Ge H., Hu Y., Yang S., Jiang X., Yang C. Preparation, characterization, and drug release behaviors of drug-loaded ε-caprolactone/L-lactide copolymer nanoparticles. J. Appl. Polym. Sci. 75:2000;874-882.
24. Riley T., Stolnik S., Heald C.R., Xiong C.D., Garnett M.C., Illum L., Davis S.S., Purkiss S.C., Barlow R.J., Gellert P.R. Physicochemical evaluation of nanoparticles assembled from poly(lactic acid)-poly(ethylene glycol) (PLA-PEG) block copolymers as drug delivery vehicles. Langmuir. 17:2001;3168-3174.
25. Zhao Y., Liang H., Wang S., Wu C. Self-assembly of poly(caprolactone-b- ethylene oxide-b-caprolactone) via a microphase inversion in water. J. Phys. Chem., B. 105:2001;848-851.
26. Allen C., Maysinger D., Eisenberg A. Nano-engineering block copolymer aggregates for drug delivery. Colloids Surf., B Biointerfaces. 16:1999;3-27.
27. Soo P.L., Luo L., Maysinger D., Eisenberg A. Incorporation and release of hydrophobic probes in biocompatible polycaprolactone-block-poly(ethylene oxide) micelles: implications for drug delivery. Langmuir. 18:2002;9996-10004.
28. Chen D., Chen H., Bei J., Wang S. Morphology and biodegradation of microspheres of polyester-polyether block copolymer based on polycaprolactone/polylactide/poly(ethylene oxide). Polym. Int. 49:2000;269-276.
29. Yang S., Lu L., Cai Y., Zhu J., Liang B., Yang C. Body distribution in mice of intravenously injected camptothecin solid lipid nanoparticles and targeting effect on brain. J. Control. Release. 59:1999;299-307.
30. Calvo P., Gouritin B., Chacun H., Desmaele D., D'Angelo J., Noel J.P., Georgin D., Fattal E., Andreux J., Couvreur P. Long-circulating PEGylated polycyanoacrylate nanoparticles as new drug carrier for brain delivery. Pharm. Res. 18:2001;1157-1166.